Alan McNally

@alanmcn1.bsky.social

6.5K followers 610 following 1.9K posts

Head of the School of Infection, Inflammation & Immunology @ Uni Birmingham. Proud Scot. Oversaw a few Covid PCR tests

Videos

Alan McNally is a professor of microbial genomics at the University of Birmingham, UK. He works on the evolutionary genomics and antimicrobial resistance in bacterial pathogens.

Source: Wikipedia

Biology 75%

Medicine 8%

Posts Replies Media Videos

Reposted by Jonathan A. Eisen, Jesse M. Shapiro, Alan McNally

John Lees @johnlees.bacpop.org · 1d

How do bacterial pangenomes evolve, what controls their dynamics, why do they exist?
Fitting a mechanistic model to 450 species from allthebacteria.org suggesting fast vs slow gene exchange (i.e. amount of MGEs) is a major differentiating factor, correlated with phylogeny rather than lifestyle

Proportion of fast genes, as a trait mapped on the bacteria-wide phylogeny

Alan McNally @alanmcn1.bsky.social · 1d

As good as the 85 Bears. Just an incredible defensive display

Alan McNally @alanmcn1.bsky.social · 1d

Finally

Alan McNally @alanmcn1.bsky.social · 1d

Kenneth Walker winning the superbowl

Alan McNally @alanmcn1.bsky.social · 1d

If this guy was in the back garden I would shut the blinds.

Alan McNally @alanmcn1.bsky.social · 1d

Not a classic for the ages

Alan McNally @alanmcn1.bsky.social · 1d

Pregame celebrating America being 250 years old

The church in our village is 980 years old…………

Alan McNally @alanmcn1.bsky.social · 1d

Without naming your job, tell me something you say over and over again at work

“Oh for fucks sake”

Dr. Kat Napaaqtuk❄️ @napaaqtuk.bsky.social · 2d

Without naming your job, tell me something you say over and over again at work.

"Always wash your hands before you leave the lab"

Teddy Zartler @quantumtessera.bsky.social · 2d

"What's the method variability?"

Alan McNally @alanmcn1.bsky.social · 1d

Nailing my colours to the mast now. Go Seahawks!!!!

Reposted by Alan McNally

Dr. Kat Napaaqtuk❄️ @napaaqtuk.bsky.social · 2d

Without naming your job, tell me something you say over and over again at work.

"Always wash your hands before you leave the lab"

Teddy Zartler @quantumtessera.bsky.social · 2d

"What's the method variability?"

Martin Stoermer @martinstoermer.bsky.social · 2d

Without naming your job, tell me something you say over and over again at work.

“Have you read the SOP?”

Alan McNally @alanmcn1.bsky.social · 2d

Watched enough of this shite. Newcastle game it is

Alan McNally @alanmcn1.bsky.social · 2d

Christ this is dreadful. It’s like U18s versus U12s!!!!!

Reposted by Alan McNally

Blair Strang @strangviruslab.bsky.social · 2d

He should have gone 2 world cups ago. This is reminiscent of his final days as Glasgow coach; over coaching everything and trying to knock a square peg in a round hole. Did no one in Scotland check what the weather forecast was?!

Alan McNally @alanmcn1.bsky.social · 2d

I think we can all agree that Graham, Kinghorn and Van der Merwe start for Scotland

Alan McNally @alanmcn1.bsky.social · 2d

This is a diabolical, ill disciplined shambles of a performance

Alan McNally @alanmcn1.bsky.social · 2d

Oh FFS

Reposted by Alan McNally

All The Right Movies @alltherightmovies.com · 3d

BLAZING SADDLES was released 52 years ago today. Acclaimed as one of the great comedies of the 1970s, and among the most popular of director Mel Brooks, the story of how it was made is a cascading waterfall of creative alternatives...

1/36

Reposted by Alan McNally

Sam Horsfield @samuelhorsfield.bsky.social · 3d

At long last, my final PhD chapter is out: we developed a novel evolutionary simulator of bacterial pangenomes, Pansim, fitting it to data from >600K genomes using a likelihood-free framework, PopPUNK-mod, to explore neutral and adaptive pangenome dynamics www.biorxiv.org/content/10.6...

www.biorxiv.org

Reposted by Alan McNally

GIMM Institute @gimminstitute.bsky.social · 3d

GIMM Fest returns September 17–19 with three days dedicated to the future of science and health, this year focusing on microbes. 🦠

Join researchers and innovators for a programme designed to promote scientific exchange and collaboration.

Reposted by Alan McNally

Mark Gillies @5goalthriller.bsky.social · 4d

He looks like the notepad next to the landline.

Reposted by Alan McNally

Paul Bronks @slendersherbet.bsky.social · 4d

Sometimes I'm late because I sit like this for too long instead of getting ready.

Alan McNally @alanmcn1.bsky.social · 4d

Relax. Just the rugby lol

Alan McNally @alanmcn1.bsky.social · 4d

Paris. Now.

a group of cartoon characters are standing in front of a christmas tree and looking surprised .

ALT: a group of cartoon characters are standing in front of a christmas tree and looking surprised .

media.tenor.com

Reposted by Alan McNally

Prof Paula Salgado @pssalgado.bsky.social · 4d

Finally an official update from #MRC regarding grant application funding and severe cuts to funded research in rounds currently under review:
www.ukri.org/blog/mrc-fun...

Not that it gives any reassurance or details beyond a comprehensive list of what is suspended.

#UKsciencefunding

MRC funding update

An update on MRC funding during UKRI’s transition, what’s changing, and the next steps for paused opportunities and reopening timelines.

www.ukri.org

Reposted by Alan McNally

Paul Bronks @slendersherbet.bsky.social · 5d

"No I'm fine, you just make sure you get your fucking video first"

Reposted by Alan McNally

Jon Cooper @joncooper-us.bsky.social · 5d

Just sayin’.

Reposted by Alan McNally

Cameron Thrash @jcamthrash.bsky.social · 5d

Accurate plasmid reconstruction from metagenomics data using assembly–alignment graphs and contrastive learning www.nature.com/articles/s41... #jcampubs

Accurate plasmid reconstruction from metagenomics data using assembly–alignment graphs and contrastive learning - Nature Biotechnology

PlasMAAG uses cross-sample information to improve plasmid reconstruction from metagenomic samples.

www.nature.com

Reposted by Alan McNally, David Stott

Viz Comic @vizcomic.bsky.social · 5d

subscriptions >>> shop.viz.co.uk/viz353bs

WHAT A con these so-called
"notebooks" are. They're
just books without any words, and
yet most of them cost much more
than best-selling novels. If I was an
author, I'd just be sending blank
pages to my publisher and going
down the pub.
lan Shakespeare,
Funtingdon-on-the-Funt

Reposted by Jesse M. Shapiro, Simon Roux, Alan McNally

Dave Baltrus 🦦 @surtlab.bsky.social · 6d

Hey y’all,

New paper out from the lab in Microbial Genomics, starting down the rabbit hole of IS elements in Paeudomonas syringae

www.microbiologyresearch.org/content/jour...

Independent, ongoing clade-specific expansions of IS5 elements in Pseudomonas syringae

Insertion sequence (IS) elements are transposable regions of DNA present in a majority of bacterial genomes. It is hypothesized that differences in distributions of IS elements across bacterial strain...

www.microbiologyresearch.org

Reposted by Alan McNally

Chris Havergal @chrishavergal.bsky.social · 7d

University of Nottingham posts £85.3 million deficit for 2024-25 after massive writedown in value of Castle Meadow and King's Meadow campuses. Also news of a £39.9 million deficit at Swansea University timeshighereducation.com/news/notting... via @patrickjack.bsky.social

Nottingham posts £85 million deficit as value of campus plummets

For sale city centre site not worth as much as thought, says university, after accounts reveal scale of financial challenge

timeshighereducation.com

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