Kristen Zuloaga
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zuloagalab.bsky.social
Kristen Zuloaga
@zuloagalab.bsky.social
Professor and Director of Graduate Studies at Albany Medical College (views my own). Sex differences, menopause, metabolic and vascular contributions to dementia. Science mom, yoga and plant lover.

http://www.zuloagalab.com/
Pinned
Check out our new paper led by Charly Abi Ghanem showing interactions between menopause & high fat diet in AD👇
alz-journals.onlinelibrary.wiley.com/doi/10.1002/...

Thx to @alzassociation.bsky.social @brightfocus.bsky.social & NINDS for funding!

Thx to collaborators Damian Zuloaga & Sally Temple
Interactions between menopause and high‐fat diet on cognition and pathology in a mouse model of Alzheimer's disease
INTRODUCTION Post-menopausal women constitute about two-thirds of those with Alzheimer's disease (AD). Menopause increases dementia risk by heightening the likelihood of metabolic disease, a well-kn...
alz-journals.onlinelibrary.wiley.com
Happy news! I was promoted to Full Professor last month! 🎉

Thank you so much to my letter writers, my former mentors, my colleagues who make going to work everyday fun, my collaborators (including my amazing husband Damian Zuloaga), and of course my rockstar lab members (past and present)! ❤️
March 20, 2025 at 11:24 AM
Check out our new paper led by Charly Abi Ghanem showing interactions between menopause & high fat diet in AD👇
alz-journals.onlinelibrary.wiley.com/doi/10.1002/...

Thx to @alzassociation.bsky.social @brightfocus.bsky.social & NINDS for funding!

Thx to collaborators Damian Zuloaga & Sally Temple
Interactions between menopause and high‐fat diet on cognition and pathology in a mouse model of Alzheimer's disease
INTRODUCTION Post-menopausal women constitute about two-thirds of those with Alzheimer's disease (AD). Menopause increases dementia risk by heightening the likelihood of metabolic disease, a well-kn...
alz-journals.onlinelibrary.wiley.com
March 20, 2025 at 10:54 AM
Reposted by Kristen Zuloaga
We’re Standing Up for Science – because science is for everyone. Thank you Rep Paul Tonko @reppaultonko.bsky.social for joining us at the NY State Capitol at Albany!
#standupforscience2025#sciencenotsilence#scienceforall #AcademicSky #science #ScienceSky 🧪
March 1, 2025 at 7:31 PM
Reposted by Kristen Zuloaga
Our latest in PNAS! 🎉

ATP-sensitive potassium channels alter glycolytic flux to modulate cortical activity and sleep

Take home message?

KATP channels are metabolic sensors under circadian control that gate glycolytic flux, arousal, & sleep/wake transitions.

www.pnas.org/doi/10.1073/...
ATP-sensitive potassium channels alter glycolytic flux to modulate cortical activity and sleep | PNAS
Metabolism plays a key role in the maintenance of sleep/wake states. Brain lactate fluctuations are a biomarker of sleep/wake transitions, where in...
www.pnas.org
February 18, 2025 at 7:48 PM
Reposted by Kristen Zuloaga
New publication from my PhD research looking at influences of sex on brain health outcomes in a rodent model of Alzheimer’s disease (AD) risk 🎉: link.springer.com/article/10.1...

Big thank you to the best co-authors, @liisagalea.bsky.social, Melike Cevizci, and Stephanie Lieblich 🙏
Sex-specific influences of APOEε4 genotype on hippocampal neurogenesis and progenitor cells in middle-aged rats - Biology of Sex Differences
Background Alzheimer’s disease (AD) disproportionately and uniquely affects females, and these sex differences are further exacerbated by the presence of Apolipoprotein (APOE) ε4 alleles, the top gene...
link.springer.com
February 11, 2025 at 8:06 PM
Thank you so much to our local news CBS6 for featuring our lab’s research this week! The interview was so fun! 👇

cbs6albany.com/news/wellnes...
Albany researchers explore menopause-dementia link with $4M NIH grant
Researchers at Albany Medical Center are investigating a potential link between menopause and dementia, a study driven by personal connections to the disease.
cbs6albany.com
December 20, 2024 at 11:37 AM
Reposted by Kristen Zuloaga
it's big, and it's a review of 601 papers on the topic - but here's an update on Neuroinflammation in Alzheimer's Disease
www.nature.com/articles/s41...

led by Michael Heneka, published in @natrevimmunol.bsky.social today

(MANY more authors listed and linked below)
Neuroinflammation in Alzheimer disease - Nature Reviews Immunology
This Review provides an in-depth examination of how inflammation contributes to neurodegeneration in Alzheimer disease. The authors explore the impact of extrinsic factors, such as brain trauma, diet ...
www.nature.com
December 10, 2024 at 3:03 AM
Thank you so much to @americanheart.bsky.social for funding my PhD student Emily Groom’s fellowship!! 🎉

So proud of Emily! Her project focuses on effects of adolescent stress on vascular contributions to ADRD

Thx to our collaborators @gabbyfredman.bsky.social, Damian Zuloaga, & Kevin Pumiglia.
December 3, 2024 at 8:59 PM
Reposted by Kristen Zuloaga
Hello Bluesky Fam! Come join the monthly Ann S. Bowers Women’s Brain Health Initiative Seminar Series for the latest science pairing women’s health + data science. With a global audience of 500 registrants from 35+ countries it’s become an amazing watering hole for the exchange of ideas. 👇🏼👇🏼👇🏼
December 3, 2024 at 12:31 AM
Reposted by Kristen Zuloaga
🧠 barriers & neurovasculature starter pack - please reply here if you are not on it yet & would like to be added 😊 go.bsky.app/RB6RXKy
November 15, 2024 at 3:30 AM
Reposted by Kristen Zuloaga
Our latest review-with @bonniee-leee.bsky.social where we pour our ❤️🧠 & soul to outline our position on why we are so passionate about harnessing the power of sex differences & within sex diff to propel precision medicine forward let us know if we convince you www.nature.com/articles/s41...
Leveraging research into sex differences and steroid hormones to improve brain health - Nature Reviews Endocrinology
This Review outlines how the effects of steroid hormones on hippocampal neuroplasticity across the adult lifespan differ between the sexes, highlighting the importance of considering sex and steroid h...
www.nature.com
November 26, 2024 at 3:11 AM
Reposted by Kristen Zuloaga
Someone had to do it! I created a starter pack for #Alzheimer’s #dementia #ADRD researchers on Bluesky. Please let me know who I left out! Hoping more and more of us will join Bluesky

go.bsky.app/22DpUEy
November 15, 2024 at 6:18 PM
Reposted by Kristen Zuloaga
Sharing again as I have added a at least 20 newbies and people how I just found out were here. Just need to get that Giles Yeo over here now go.bsky.app/NRoqMvp
November 16, 2024 at 4:50 PM
Reposted by Kristen Zuloaga
Extremely proud of Rebecca Wallings & Team in #TanseyLab3.0 for these high-impact findings in @sciencetranslationalmedicine www.science.org/doi/10.1126/...
The R1441C-Lrrk2 mutation induces myeloid immune cell exhaustion in an age- and sex-dependent manner in mice
The R1441C-Lrrk2 mutation causes age-acquired immune exhaustion in mouse macrophages in a sex-dependent manner.
www.science.org
November 24, 2024 at 8:56 PM
Reposted by Kristen Zuloaga
Aging starter pack!

go.bsky.app/5UXXaDA
November 22, 2024 at 4:23 AM
Reposted by Kristen Zuloaga
Welcome to Bluesky @mikelehman.bsky.social

70+ people in the starter pack now so worth checking out again as lots of newbies added 😀

go.bsky.app/T3VKPCw
November 22, 2024 at 10:22 AM
Reposted by Kristen Zuloaga
Here’s our new review lead by @rominagl4.bsky.social on the roller coaster of central & peripheral inflammatory signalling during pregnancy & the postpartum & it’s relation to psychiatric disease risk in short term & neurodegenerative in long term www.sciencedirect.com/science/arti...
Inflammatory signalling during the perinatal period: Implications for short- and long-term disease risk
During pregnancy and the postpartum, there are dynamic fluctuations in steroid and peptide hormone levels as well as inflammatory signalling. These ch…
www.sciencedirect.com
November 22, 2024 at 12:12 PM
We have openings at all levels (PhD student, tech, postdocs)
Read below about our newest project! 👇

www.albanymed.org/news/4m-nih-...

PhD deadline to apply is Dec 1st: www.amc.edu/education/ba...

Tech and postdoc app info here: www.zuloagalab.com/join-our-tea...
$4M NIH Grant Awarded for Dementia Research
Albany Medical College's Kristen Zuloaga, PhD received a $4 million NIH grant to study how menopause impacts dementia and to test a potential new treatment.
www.albanymed.org
November 21, 2024 at 12:22 PM
Reposted by Kristen Zuloaga
Interested in a PhD or MS in Neuroscience?

PhD applications are due Dec 1st!
No GREs
We value and welcome diversity!

Apply to @AlbanyMed! 👇

#NeuroPhD #phdlife #NeurosciencePHD
November 20, 2024 at 11:40 PM