Zechner Lab
@zechnerlab.bsky.social
Research group at SISSA / Trieste. Interested in stochastic processes in biology & biophysics. Posts by C. Zechner.
Reposted by Zechner Lab
Two 2-year postdoc positions in my theory group — for studying the interplay between metabolism and morphogenesis at the edge of the Calanques and the Mediterranean. More information can be found on: euraxess.ec.europa.eu/jobs/381176
#biophysics
#biophysics
Postdoc in Theoretical Biophysics
Two postdoc positions (each for two years, funded by Amidex Foundation) are available in theoretical biophysics within the theory group at DyNaMo (Aix-Marseille University).
euraxess.ec.europa.eu
October 27, 2025 at 4:19 PM
Two 2-year postdoc positions in my theory group — for studying the interplay between metabolism and morphogenesis at the edge of the Calanques and the Mediterranean. More information can be found on: euraxess.ec.europa.eu/jobs/381176
#biophysics
#biophysics
Reposted by Zechner Lab
Really excited to share our latest work led by @mattiaubertini.bsky.social and @nesslfy.bsky.social: we report that cohesin loop extrusion creates rare but long-lived encounters between genomic sequences which underlie efficient enhancer-promoter communication.
www.biorxiv.org/content/10.1...
A🧵👇
www.biorxiv.org/content/10.1...
A🧵👇
September 24, 2025 at 9:45 PM
Really excited to share our latest work led by @mattiaubertini.bsky.social and @nesslfy.bsky.social: we report that cohesin loop extrusion creates rare but long-lived encounters between genomic sequences which underlie efficient enhancer-promoter communication.
www.biorxiv.org/content/10.1...
A🧵👇
www.biorxiv.org/content/10.1...
A🧵👇
Reposted by Zechner Lab
Thanks a lot to @elisecutts.bsky.social for nicely highlighting and putting in context our article! It was very interesting to discuss together, notably about the analogies between the emergence of order in Hydra and other physical phenomena.
Hydra are ~basically~ immortal.
Shred 50 of the lil guys to bits and pack their cells in a blob, and that blob will grow into a new Hydra... albeit with a few extra heads!
This week's post is a Q&A @anaisbailles.bsky.social @mpi-cbg.de about the physics of how Hydra coax order from chaos.🧪⚛️
Shred 50 of the lil guys to bits and pack their cells in a blob, and that blob will grow into a new Hydra... albeit with a few extra heads!
This week's post is a Q&A @anaisbailles.bsky.social @mpi-cbg.de about the physics of how Hydra coax order from chaos.🧪⚛️
Hydra are a cosmos in a cuvette
Anaïs Bailles on astrophysics and immortal animals
www.reviewertoo.com
September 12, 2025 at 1:56 PM
Thanks a lot to @elisecutts.bsky.social for nicely highlighting and putting in context our article! It was very interesting to discuss together, notably about the analogies between the emergence of order in Hydra and other physical phenomena.
Reposted by Zechner Lab
Great work! Congratulations you all & especially to
@carldmodes.bsky.social who joined today after a lot of arm twisting by Caren...
@carldmodes.bsky.social who joined today after a lot of arm twisting by Caren...
The Friday second try: After intense work, especially in the last year, this work is finally ready to be seen by the public. Led by @apramos.bsky.social and great collaboration with @carldmodes.bsky.social group especially @liormoneta.bsky.social : www.biorxiv.org/content/10.1...
The Optic cup is actively shape programmed by independently patterned apical forces
During morphogenesis, initially flat tissues often must transition into complex 3D shapes, reminiscent of shape-programmable systems in physics and engineering. One key question in developmental biolo...
www.biorxiv.org
August 22, 2025 at 2:13 PM
Great work! Congratulations you all & especially to
@carldmodes.bsky.social who joined today after a lot of arm twisting by Caren...
@carldmodes.bsky.social who joined today after a lot of arm twisting by Caren...
Reposted by Zechner Lab
Out today in @nature.com: Together with the Honigmann, Shevchenko, Drobot and Hof labs, we present a general workflow for imaging the localization and transport of individual lipids in cells and mapping their metabolism.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
August 21, 2025 at 5:19 AM
Out today in @nature.com: Together with the Honigmann, Shevchenko, Drobot and Hof labs, we present a general workflow for imaging the localization and transport of individual lipids in cells and mapping their metabolism.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Zechner Lab
Our beautiful Hydra made the cover!!! 😍😍😍
An experiment performed by Pavel Mejstrik with a HCR protocol by @giuliaserafini.bsky.social, @paveltomancak.bsky.social lab @mpi-cbg.de
Actin fibers in blue, nuclei in orange.
An experiment performed by Pavel Mejstrik with a HCR protocol by @giuliaserafini.bsky.social, @paveltomancak.bsky.social lab @mpi-cbg.de
Actin fibers in blue, nuclei in orange.
August 13, 2025 at 8:51 AM
Our beautiful Hydra made the cover!!! 😍😍😍
An experiment performed by Pavel Mejstrik with a HCR protocol by @giuliaserafini.bsky.social, @paveltomancak.bsky.social lab @mpi-cbg.de
Actin fibers in blue, nuclei in orange.
An experiment performed by Pavel Mejstrik with a HCR protocol by @giuliaserafini.bsky.social, @paveltomancak.bsky.social lab @mpi-cbg.de
Actin fibers in blue, nuclei in orange.
Reposted by Zechner Lab
Our first #Hydra paper. @anaisbailles.bsky.social all the way, with crucial theory contributions from Carl Modes and @zechnerlab.bsky.social Hydra maintenance by Heino Andreas and HCR by Giulia Serafini. Teamwork. Many thanks to the generous Hydra research community.
Very happy that the first article from my postdoc work in the Tomancak lab is now published @PNAS! www.pnas.org/doi/10.1073/.... We studied the self-organization of actin in aggregates made from Hydra cells. Thread below (1/9)
August 6, 2025 at 3:13 PM
Our first #Hydra paper. @anaisbailles.bsky.social all the way, with crucial theory contributions from Carl Modes and @zechnerlab.bsky.social Hydra maintenance by Heino Andreas and HCR by Giulia Serafini. Teamwork. Many thanks to the generous Hydra research community.
Reposted by Zechner Lab
Stretching the immortal Hydra. Publication by @paveltomancak.bsky.social group with Carl Modes @mpi-cbg.de & @zechnerlab.bsky.social shows how cells can create a new organism from scratch by coordinating their mechanical properties. @anaisbailles.bsky.social @pnas.org www.mpi-cbg.de/news-outreac...
Stretching the immortal Hydra
Dresden researchers show how cells can create a new organism from scratch by coordinating their mechanical properties.
www.mpi-cbg.de
August 5, 2025 at 12:45 PM
Stretching the immortal Hydra. Publication by @paveltomancak.bsky.social group with Carl Modes @mpi-cbg.de & @zechnerlab.bsky.social shows how cells can create a new organism from scratch by coordinating their mechanical properties. @anaisbailles.bsky.social @pnas.org www.mpi-cbg.de/news-outreac...
Reposted by Zechner Lab
Novel Research in Biological Artificial Intelligence: Expressions of interest and nominations for a Max Planck Director to lead research in the field of Biological Artificial Intelligence @mpi-cbg.de and @csbdresden.bsky.social. More information: www.mpi-cbg.de/news-outreac...
Novel Research in Biological Artificial Intelligence
Expressions of interest and nominations for a Max Planck Director to lead research in the field of Biological Artificial Intelligence.
www.mpi-cbg.de
June 26, 2025 at 11:26 AM
Novel Research in Biological Artificial Intelligence: Expressions of interest and nominations for a Max Planck Director to lead research in the field of Biological Artificial Intelligence @mpi-cbg.de and @csbdresden.bsky.social. More information: www.mpi-cbg.de/news-outreac...
Reposted by Zechner Lab
We are searching for an AI researcher in lab automation, statistical ML and (theoretical) physics AI for bio/med. Expression of interest and nominations welcome!!!
Novel Research in Biological Artificial Intelligence: Expressions of interest and nominations for a Max Planck Director to lead research in the field of Biological Artificial Intelligence @mpi-cbg.de and @csbdresden.bsky.social. More information: www.mpi-cbg.de/news-outreac...
Novel Research in Biological Artificial Intelligence
Expressions of interest and nominations for a Max Planck Director to lead research in the field of Biological Artificial Intelligence.
www.mpi-cbg.de
June 26, 2025 at 9:10 PM
We are searching for an AI researcher in lab automation, statistical ML and (theoretical) physics AI for bio/med. Expression of interest and nominations welcome!!!
Reposted by Zechner Lab
We are looking for a research assistant to join our lab and support ongoing projects with genome engineering in mouse embryonic stem cells! Please get in touch if you are interested.
www.fmi.ch/education-ca...
www.fmi.ch/education-ca...
Friedrich Miescher Institute, open position
Friedrich Miescher Institute, open position
www.fmi.ch
June 26, 2025 at 3:04 PM
We are looking for a research assistant to join our lab and support ongoing projects with genome engineering in mouse embryonic stem cells! Please get in touch if you are interested.
www.fmi.ch/education-ca...
www.fmi.ch/education-ca...
Reposted by Zechner Lab
(1/n) Thread @matteomazzocca.bsky.social @domenicnarducci.bsky.social Simon Grosse-Holz @jessematthias.bsky.social preprint
Q: how does chromatin move?
Using MINFLUX, SPT & SRLCI, we track chromatin dynamics across 7 orders of magnitude in time to provide answers www.biorxiv.org/content/10.1...
Q: how does chromatin move?
Using MINFLUX, SPT & SRLCI, we track chromatin dynamics across 7 orders of magnitude in time to provide answers www.biorxiv.org/content/10.1...
May 15, 2025 at 12:37 PM
(1/n) Thread @matteomazzocca.bsky.social @domenicnarducci.bsky.social Simon Grosse-Holz @jessematthias.bsky.social preprint
Q: how does chromatin move?
Using MINFLUX, SPT & SRLCI, we track chromatin dynamics across 7 orders of magnitude in time to provide answers www.biorxiv.org/content/10.1...
Q: how does chromatin move?
Using MINFLUX, SPT & SRLCI, we track chromatin dynamics across 7 orders of magnitude in time to provide answers www.biorxiv.org/content/10.1...
Many congratulations to Anne for defending her PhD this week…excellent results and presentation! We wish you all the best for your future career!
March 28, 2025 at 8:51 AM
Many congratulations to Anne for defending her PhD this week…excellent results and presentation! We wish you all the best for your future career!
Reposted by Zechner Lab
We are finalizing the program of the @cecamevents.bsky.social RNA modelling across scales www.cecam.org/workshop-det... at SISSA, Trieste, Italy, May 19-22. Please note that we still have a few slots for in person attendance. We will accept applications for the next few weeks, until fully booked!
March 27, 2025 at 5:15 PM
We are finalizing the program of the @cecamevents.bsky.social RNA modelling across scales www.cecam.org/workshop-det... at SISSA, Trieste, Italy, May 19-22. Please note that we still have a few slots for in person attendance. We will accept applications for the next few weeks, until fully booked!
Reposted by Zechner Lab
Come to #Prague for #Woodstock2025. What is it? A scientific conference unlike any other. Think #BurningMan or #MusicFestival but #science themed. It'll have two parts - decentralised sessions spread in #Prague (sightsee as you move around) & #campsite event to wrap it up (1/7)
March 2, 2025 at 11:52 AM
Come to #Prague for #Woodstock2025. What is it? A scientific conference unlike any other. Think #BurningMan or #MusicFestival but #science themed. It'll have two parts - decentralised sessions spread in #Prague (sightsee as you move around) & #campsite event to wrap it up (1/7)
Reposted by Zechner Lab
"Cacio e pepe" physics: In arxiv.org/abs/2501.00536v1, eight Italian scientists from the Max Planck Institute for the Physics of Complex Systems explain the physics behind a perfect dish of "cacio e pepe" and how to eschew the dreaded "mozzarella phase" - work featured @nytimes.com.
January 29, 2025 at 8:50 PM
"Cacio e pepe" physics: In arxiv.org/abs/2501.00536v1, eight Italian scientists from the Max Planck Institute for the Physics of Complex Systems explain the physics behind a perfect dish of "cacio e pepe" and how to eschew the dreaded "mozzarella phase" - work featured @nytimes.com.
Congratulations Tommaso for an excellent PhD defense! Very well done!
February 13, 2025 at 4:56 PM
Congratulations Tommaso for an excellent PhD defense! Very well done!
Excited to share our new work with Frank Jülicher on noise control & concentration buffering in intracellular condensates! There has been confusion about these concepts, which we aim to address in this paper.
www.cell.com/cell-systems...
www.cell.com/cell-systems...
February 12, 2025 at 8:47 AM
Excited to share our new work with Frank Jülicher on noise control & concentration buffering in intracellular condensates! There has been confusion about these concepts, which we aim to address in this paper.
www.cell.com/cell-systems...
www.cell.com/cell-systems...
Reposted by Zechner Lab
Starting the new season of seminars in Molecular and Statistical Biophysics at SISSA! Gareth Tribello today gave a talk with title “Reconnaissance Metadynamics Rides Again”
February 4, 2025 at 8:22 PM
Starting the new season of seminars in Molecular and Statistical Biophysics at SISSA! Gareth Tribello today gave a talk with title “Reconnaissance Metadynamics Rides Again”
Please share! There are two postdoc opportunities at the Molecular and Statistical Biophysics group at SISSA. Join us in beautiful Trieste! More information at msb.sissa.it/join-us/
January 17, 2025 at 11:13 AM
Please share! There are two postdoc opportunities at the Molecular and Statistical Biophysics group at SISSA. Join us in beautiful Trieste! More information at msb.sissa.it/join-us/
Reposted by Zechner Lab
Excited to share James Jusuf's preprint:
By integrating Micro-C with SuperRes Live-Imaging we can calibrate genomics&imaging to perform absolute quantification of looping (e.g. this loop is present 3%)
We quantify mESC 36k loops: are generally rare (2.3%)
www.biorxiv.org/content/10.1...
By integrating Micro-C with SuperRes Live-Imaging we can calibrate genomics&imaging to perform absolute quantification of looping (e.g. this loop is present 3%)
We quantify mESC 36k loops:
www.biorxiv.org/content/10.1...
January 16, 2025 at 1:35 PM
Excited to share James Jusuf's preprint:
By integrating Micro-C with SuperRes Live-Imaging we can calibrate genomics&imaging to perform absolute quantification of looping (e.g. this loop is present 3%)
We quantify mESC 36k loops: are generally rare (2.3%)
www.biorxiv.org/content/10.1...
By integrating Micro-C with SuperRes Live-Imaging we can calibrate genomics&imaging to perform absolute quantification of looping (e.g. this loop is present 3%)
We quantify mESC 36k loops:
www.biorxiv.org/content/10.1...
Reposted by Zechner Lab
📢 Post-doc opportunity alert! Join the Molecular and Statistical Biophysics group at SISSA. Choose your mentor from Giovanni Bussi, Cristian Micheletti, or Angelo Rosa, or collaborate across these groups. www.bussilab.org/joinus#postd... #joinus Please reshare!
Join Us
RNA, molecular dynamics, and more
www.bussilab.org
January 15, 2025 at 1:28 PM
📢 Post-doc opportunity alert! Join the Molecular and Statistical Biophysics group at SISSA. Choose your mentor from Giovanni Bussi, Cristian Micheletti, or Angelo Rosa, or collaborate across these groups. www.bussilab.org/joinus#postd... #joinus Please reshare!
Exciting news! As of today, our group is part of SISSA in Trieste. Time to say THANK YOU to all current and past group members, collaborators and mentors and to @mpicbg.bsky.social for hosting us for 8 amazing years! If you are interested in working with us in Trieste, please get in touch!
December 2, 2024 at 3:08 PM
Exciting news! As of today, our group is part of SISSA in Trieste. Time to say THANK YOU to all current and past group members, collaborators and mentors and to @mpicbg.bsky.social for hosting us for 8 amazing years! If you are interested in working with us in Trieste, please get in touch!