Xavier Graña Lab
@xaviergranalab.bsky.social
Professor, Fels Cancer Institute at Temple University School of Medicine. My lab works on #kinase and #phosphatase signaling during the #cellcycle in normal and #cancer cells.
Co-Director of Graduate and HUR Undergraduate Programs.
Co-Director of Graduate and HUR Undergraduate Programs.
Reposted by Xavier Graña Lab
Here we are, happy to join the community!
January 13, 2025 at 7:26 PM
Here we are, happy to join the community!
Reposted by Xavier Graña Lab
OK I am annoyed by these misleading science graphics
swiping a sequencing gel up and down?
playing a few frames of a timelapse movie ad nauseam?
nothing is explained
everything is 'spooky' and 'weird'
it all reflects the easy seduction of scientific illiteracy
swiping a sequencing gel up and down?
playing a few frames of a timelapse movie ad nauseam?
nothing is explained
everything is 'spooky' and 'weird'
it all reflects the easy seduction of scientific illiteracy
Doctors Thought They Knew What a Genetic Disease Is. They Were Wrong.
Mutations that happen throughout a person’s life may contribute to disease more than we realized.
www.theatlantic.com
January 4, 2025 at 6:28 AM
OK I am annoyed by these misleading science graphics
swiping a sequencing gel up and down?
playing a few frames of a timelapse movie ad nauseam?
nothing is explained
everything is 'spooky' and 'weird'
it all reflects the easy seduction of scientific illiteracy
swiping a sequencing gel up and down?
playing a few frames of a timelapse movie ad nauseam?
nothing is explained
everything is 'spooky' and 'weird'
it all reflects the easy seduction of scientific illiteracy
Reposted by Xavier Graña Lab
I can’t wait for 1-800-ALPHAFOLD wher eyou can just shout “Siri: Met-Asp-Arg…” and it will fold for you 🤣
December 20, 2024 at 11:13 AM
I can’t wait for 1-800-ALPHAFOLD wher eyou can just shout “Siri: Met-Asp-Arg…” and it will fold for you 🤣
Reposted by Xavier Graña Lab
Download our database of 313 different postdoctoral fellowships.
For each entry, we provide link to funder, description, amount, deadline, and eligibility criteria (e.g. citizenship).
Download our database here: research.jhu.edu/rdt/funding-...
For each entry, we provide link to funder, description, amount, deadline, and eligibility criteria (e.g. citizenship).
Download our database here: research.jhu.edu/rdt/funding-...
November 16, 2024 at 7:05 PM
Download our database of 313 different postdoctoral fellowships.
For each entry, we provide link to funder, description, amount, deadline, and eligibility criteria (e.g. citizenship).
Download our database here: research.jhu.edu/rdt/funding-...
For each entry, we provide link to funder, description, amount, deadline, and eligibility criteria (e.g. citizenship).
Download our database here: research.jhu.edu/rdt/funding-...
Reposted by Xavier Graña Lab
A chemical-genetic system to rapidly inhibit the PP2A-B56 phosphatase https://www.biorxiv.org/content/10.1101/2024.07.23.604754v1
A chemical-genetic system to rapidly inhibit the PP2A-B56 phosphatase https://www.biorxiv.org/content/10.1101/2024.07.23.604754v1
Serine-threonine phosphatases have been challenging to study because of the lack of specific inhibit
www.biorxiv.org
July 24, 2024 at 3:30 AM
A chemical-genetic system to rapidly inhibit the PP2A-B56 phosphatase https://www.biorxiv.org/content/10.1101/2024.07.23.604754v1
Reposted by Xavier Graña Lab
Very excited that our paper describing a critical role for the PNUTS-PP1 phosphatase complex in transcription pause release is up online! This was a massive team effort with @edimitrova.bsky.social and the rest of the @robklose.bsky.social lab www.cell.com/molecular-ce... A short thread: (1/8)
The PNUTS phosphatase complex controls transcription pause release
Kelley et al. discover that the PNUTS phosphatase complex plays an essential role
in gene transcription by controlling RNA polymerase II pause release. PNUTS achieves
this through its TND, which recog...
www.cell.com
November 26, 2024 at 4:18 PM
Very excited that our paper describing a critical role for the PNUTS-PP1 phosphatase complex in transcription pause release is up online! This was a massive team effort with @edimitrova.bsky.social and the rest of the @robklose.bsky.social lab www.cell.com/molecular-ce... A short thread: (1/8)
Reposted by Xavier Graña Lab
November 26, 2024 at 11:52 AM
Reposted by Xavier Graña Lab
Users working on #phosphatases. Keep up to date with all posts from the community. If you want adding/removing let me know. If you can't decide whether you should be included, then ask yourself - would I go to a phosphatase meeting in person? If yes, then sign up!
bsky.app/profile/did:...
bsky.app/profile/did:...
November 26, 2024 at 10:46 AM
Users working on #phosphatases. Keep up to date with all posts from the community. If you want adding/removing let me know. If you can't decide whether you should be included, then ask yourself - would I go to a phosphatase meeting in person? If yes, then sign up!
bsky.app/profile/did:...
bsky.app/profile/did:...
Reposted by Xavier Graña Lab
Understanding the origin of eukaryotic cells is one of the biggest puzzles in biology 🧩 As genomic data expand, painting a clear picture of LECA requires analytical resources and a commitment to data sharing. This paper led by T. R. emphasizes a community-driven approach to tackle this complexity.
What did the Last Eukaryotic Common Ancestor (#LECA) look like? Consensus View in #PLOSBiology; massive authorship including @AncestralState, @lauraeme.bsky.social, John Archbald, @andrewjroger.bsky.social, @dackslabecb.bsky.social, Jeremy Wideman. plos.io/4g0alq4
November 25, 2024 at 8:01 PM
Understanding the origin of eukaryotic cells is one of the biggest puzzles in biology 🧩 As genomic data expand, painting a clear picture of LECA requires analytical resources and a commitment to data sharing. This paper led by T. R. emphasizes a community-driven approach to tackle this complexity.
Reposted by Xavier Graña Lab
🎨 In case anyone need…
The NIH BioArt Source is an awesome library of *free* professionally drawn illustrations for scientific presentations or figures. Downloadable in HD. Thank you NIH for this invaluable tool 🙏!
Check it out 👇
bioart.niaid.nih.gov
The NIH BioArt Source is an awesome library of *free* professionally drawn illustrations for scientific presentations or figures. Downloadable in HD. Thank you NIH for this invaluable tool 🙏!
Check it out 👇
bioart.niaid.nih.gov
November 23, 2024 at 3:50 PM
🎨 In case anyone need…
The NIH BioArt Source is an awesome library of *free* professionally drawn illustrations for scientific presentations or figures. Downloadable in HD. Thank you NIH for this invaluable tool 🙏!
Check it out 👇
bioart.niaid.nih.gov
The NIH BioArt Source is an awesome library of *free* professionally drawn illustrations for scientific presentations or figures. Downloadable in HD. Thank you NIH for this invaluable tool 🙏!
Check it out 👇
bioart.niaid.nih.gov
Reposted by Xavier Graña Lab
Did you know there’s a site to search for starter packs of people to follow? Built by @mubashariqbal.com
blueskydirectory.com/starter-pack...
blueskydirectory.com/starter-pack...
Bluesky Starter Packs - Bluesky Directory
Browse a list of Bluesky Starter Packs. Discover and connect with your community on Bluesky
blueskydirectory.com
November 23, 2024 at 9:43 PM
Did you know there’s a site to search for starter packs of people to follow? Built by @mubashariqbal.com
blueskydirectory.com/starter-pack...
blueskydirectory.com/starter-pack...
Reposted by Xavier Graña Lab
“Like ‘old Twitter’: The scientific community finds a new home on @bsky.app
Commentary in #Science
www.science.org/content/arti...
Commentary in #Science
www.science.org/content/arti...
Like ‘old Twitter’: The scientific community finds a new home on Bluesky
After recent changes to Elon Musk’s X, a gradual migration turns into a stampede
www.science.org
November 24, 2024 at 3:02 PM
“Like ‘old Twitter’: The scientific community finds a new home on @bsky.app
Commentary in #Science
www.science.org/content/arti...
Commentary in #Science
www.science.org/content/arti...
Reposted by Xavier Graña Lab
"Dark TFs": new manuscript mapped 166 uncharacterized human transcription factors, finding half bind genomic "dark matter," often closed chromatin rich in transposable elements.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
November 19, 2024 at 11:41 PM
"Dark TFs": new manuscript mapped 166 uncharacterized human transcription factors, finding half bind genomic "dark matter," often closed chromatin rich in transposable elements.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Xavier Graña Lab
Exploiting cell cycle-dependent dephosphorylation for mitosis-specific protein recruitment.
Nice review #mitosis #CellCycle
www.nature.com/articles/s41...
Nice review #mitosis #CellCycle
www.nature.com/articles/s41...
Exploiting cell cycle-dependent dephosphorylation for mitosis-specific protein recruitment - Nature Reviews Molecular Cell Biology
In this Tools of the Trade article, Cao (Baskin lab) discusses the development of MARS, which enables mitosis-specific recruitment of enzymes to the plasma membrane, exploiting the cell cycle’s natura...
www.nature.com
November 20, 2024 at 10:29 PM
Exploiting cell cycle-dependent dephosphorylation for mitosis-specific protein recruitment.
Nice review #mitosis #CellCycle
www.nature.com/articles/s41...
Nice review #mitosis #CellCycle
www.nature.com/articles/s41...
Reposted by Xavier Graña Lab
A list of people interested in cell cycle entry and exit. Reply to this post if you want to be added. #senescence #cellcycle
go.bsky.app/7hEivbt
go.bsky.app/7hEivbt
November 17, 2024 at 6:32 PM
A list of people interested in cell cycle entry and exit. Reply to this post if you want to be added. #senescence #cellcycle
go.bsky.app/7hEivbt
go.bsky.app/7hEivbt
Reposted by Xavier Graña Lab
Looking to expand this group if you can help spread the word or add anyone I missed… @alexisbarr.bsky.social @dnatarheel.bsky.social @purvislab.bsky.social
A list of people interested in cell cycle entry and exit. Reply to this post if you want to be added. #senescence #cellcycle
go.bsky.app/7hEivbt
go.bsky.app/7hEivbt
November 17, 2024 at 7:46 PM
Looking to expand this group if you can help spread the word or add anyone I missed… @alexisbarr.bsky.social @dnatarheel.bsky.social @purvislab.bsky.social
Reposted by Xavier Graña Lab
Tough to abandon Twitter (can’t bring myself to call it “X”), but the time is well past.
November 16, 2024 at 12:02 AM
Tough to abandon Twitter (can’t bring myself to call it “X”), but the time is well past.
Hi, I started moving from X. I used www.sky-follower-bridge.dev. It help me find about 20% of the people who I was following on X. Thanks, Adrian.
Sky Follower Bridge
Instantly find and follow the same users from your 𝕏 followers on Bluesky
www.sky-follower-bridge.dev
November 18, 2024 at 12:01 AM
Hi, I started moving from X. I used www.sky-follower-bridge.dev. It help me find about 20% of the people who I was following on X. Thanks, Adrian.