Jason Withorn
@withornjason.bsky.social
5th year chemistry PhD candidate (biochemistry focused) in the Dr. Elizabeth Boon’s lab at Stony Brook University studying biofilm signaling in Pseudomonas aeruginosa.
Reposted by Jason Withorn
New work from the lab! Sometimes going beyond prototypical strains such as PAO1 or PA14 tells a more complex and nuanced story.
PqsE is conserved and functionally relevant in Pseudomonas aeruginosa https://www.biorxiv.org/content/10.1101/2025.05.16.654539v1
May 18, 2025 at 4:03 AM
New work from the lab! Sometimes going beyond prototypical strains such as PAO1 or PA14 tells a more complex and nuanced story.
Check out our latest Pre-print from the @groupboon.bsky.social!
Following the downstream signaling of NO-mediated biofilm dispersal, we examined the role of all components of the Gac Multi-Kinase Network and identified NahK (and RetS) have predominant control over regulating biofilm through RsmA!
Following the downstream signaling of NO-mediated biofilm dispersal, we examined the role of all components of the Gac Multi-Kinase Network and identified NahK (and RetS) have predominant control over regulating biofilm through RsmA!
Pseudomonas aeruginosa uses kinases NahK and RetS to control the motile-biofilm switch https://www.biorxiv.org/content/10.1101/2025.09.24.678285v1
September 25, 2025 at 5:50 PM
Check out our latest Pre-print from the @groupboon.bsky.social!
Following the downstream signaling of NO-mediated biofilm dispersal, we examined the role of all components of the Gac Multi-Kinase Network and identified NahK (and RetS) have predominant control over regulating biofilm through RsmA!
Following the downstream signaling of NO-mediated biofilm dispersal, we examined the role of all components of the Gac Multi-Kinase Network and identified NahK (and RetS) have predominant control over regulating biofilm through RsmA!
Reposted by Jason Withorn
The histidine kinase NahK in Pseudomonas aeruginosa is essential for nitric oxide-stress resistance in nutrient starved media https://www.biorxiv.org/content/10.1101/2025.07.03.662950v1
July 4, 2025 at 3:17 AM
The histidine kinase NahK in Pseudomonas aeruginosa is essential for nitric oxide-stress resistance in nutrient starved media https://www.biorxiv.org/content/10.1101/2025.07.03.662950v1
Reposted by Jason Withorn
Check out the latest preprint from our lab! 🎉🎉🎉
PhD student Sweta Anantharaman (not on BlueSky) investigated how the NahK signaling system plays a role in NO stress in differing nutrient conditions!
Sweta went above and beyond exploring new research areas in our laboratory! Excited for reviews!
PhD student Sweta Anantharaman (not on BlueSky) investigated how the NahK signaling system plays a role in NO stress in differing nutrient conditions!
Sweta went above and beyond exploring new research areas in our laboratory! Excited for reviews!
The histidine kinase NahK in Pseudomonas aeruginosa is essential for nitric oxide-stress resistance in nutrient starved media https://www.biorxiv.org/content/10.1101/2025.07.03.662950v1
July 13, 2025 at 9:15 PM
Check out the latest preprint from our lab! 🎉🎉🎉
PhD student Sweta Anantharaman (not on BlueSky) investigated how the NahK signaling system plays a role in NO stress in differing nutrient conditions!
Sweta went above and beyond exploring new research areas in our laboratory! Excited for reviews!
PhD student Sweta Anantharaman (not on BlueSky) investigated how the NahK signaling system plays a role in NO stress in differing nutrient conditions!
Sweta went above and beyond exploring new research areas in our laboratory! Excited for reviews!
Best part of being in Boston is getting the chance to meet up with @eboros.bsky.social alumni @jennchemm.bsky.social and Kirsten Martin!
June 9, 2025 at 12:25 PM
Best part of being in Boston is getting the chance to meet up with @eboros.bsky.social alumni @jennchemm.bsky.social and Kirsten Martin!
@groupboon.bsky.social goes to Boston! Can’t wait to hear about all the new exciting bacterial research over the next two days at @bostonbacteria.bsky.social!
June 8, 2025 at 11:25 AM
@groupboon.bsky.social goes to Boston! Can’t wait to hear about all the new exciting bacterial research over the next two days at @bostonbacteria.bsky.social!
Reposted by Jason Withorn
Congratulations to our undergraduate researchers, Xingyu Xiao and Simran Singh, on their selection to participate in the 2025 URECA Summer Research Program! This opportunity allows for a 10-week full-time summer research with an awarded stipend. Proud of you both! #TotheBoon
April 23, 2025 at 7:42 PM
Congratulations to our undergraduate researchers, Xingyu Xiao and Simran Singh, on their selection to participate in the 2025 URECA Summer Research Program! This opportunity allows for a 10-week full-time summer research with an awarded stipend. Proud of you both! #TotheBoon
Reposted by Jason Withorn
Congratulations to our very own @withornjason.bsky.social for winning the 2025 Stony Brook University President's Award to Distinguished Doctoral Students! We are very proud of you.
April 4, 2025 at 2:00 PM
Congratulations to our very own @withornjason.bsky.social for winning the 2025 Stony Brook University President's Award to Distinguished Doctoral Students! We are very proud of you.
Me my whole PhD: why do people look at polymicrobial systems. Just pick your favorite.
*does one polymicrobial experiment this week and finally sees the light
*does one polymicrobial experiment this week and finally sees the light
a man with glasses is surrounded by a glowing circle and the website pmitf.com is displayed below him
ALT: a man with glasses is surrounded by a glowing circle and the website pmitf.com is displayed below him
media.tenor.com
February 16, 2025 at 12:43 AM
Me my whole PhD: why do people look at polymicrobial systems. Just pick your favorite.
*does one polymicrobial experiment this week and finally sees the light
*does one polymicrobial experiment this week and finally sees the light
Reposted by Jason Withorn
Come join our faculty! We’re hiring.
February 13, 2025 at 9:18 PM
Come join our faculty! We’re hiring.
Reposted by Jason Withorn
Inhibitors of the PqsR Quorum-Sensing Receptor Reveal Differential Roles for PqsE and RhlI in Control of Phenazine Production https://www.biorxiv.org/content/10.1101/2025.02.10.637488v1
February 12, 2025 at 3:20 AM
Inhibitors of the PqsR Quorum-Sensing Receptor Reveal Differential Roles for PqsE and RhlI in Control of Phenazine Production https://www.biorxiv.org/content/10.1101/2025.02.10.637488v1
Reposted by Jason Withorn
ÅNGSTRÖM-RESOLUTION IMAGING OF CELL-SURFACE GLYCANS 🧬🎨🍬
The glycocalyx, our cells' sugar coat, holds secrets in immunology, cancer, viral infections, and more. Visualizing its molecular architecture was impossible… until now. #glycotime #microscopy
www.biorxiv.org/content/10.1...
The glycocalyx, our cells' sugar coat, holds secrets in immunology, cancer, viral infections, and more. Visualizing its molecular architecture was impossible… until now. #glycotime #microscopy
www.biorxiv.org/content/10.1...
February 10, 2025 at 8:21 AM
ÅNGSTRÖM-RESOLUTION IMAGING OF CELL-SURFACE GLYCANS 🧬🎨🍬
The glycocalyx, our cells' sugar coat, holds secrets in immunology, cancer, viral infections, and more. Visualizing its molecular architecture was impossible… until now. #glycotime #microscopy
www.biorxiv.org/content/10.1...
The glycocalyx, our cells' sugar coat, holds secrets in immunology, cancer, viral infections, and more. Visualizing its molecular architecture was impossible… until now. #glycotime #microscopy
www.biorxiv.org/content/10.1...
Reposted by Jason Withorn
The WHO research agenda for #AMR in human health has identified 40 research priorities to be addressed by 2030, focusing on bacterial and fungal pathogens critical for AMR. Target is to encourage evidence generation for effective AMR policy translation
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
February 4, 2025 at 9:02 AM
The WHO research agenda for #AMR in human health has identified 40 research priorities to be addressed by 2030, focusing on bacterial and fungal pathogens critical for AMR. Target is to encourage evidence generation for effective AMR policy translation
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Reposted by Jason Withorn
The @jrbour.bsky.social Lab establishes a potential chemical basis for a low-power, small-footprint inhaled nitric oxide (iNO) delivery system. @angewandtechemie.bsky.social. #wsuchemistry #ResearchInDetroit #ChemSky
onlinelibrary.wiley.com/doi/10.1002/...
onlinelibrary.wiley.com/doi/10.1002/...
On‐Demand Nitric Oxide Generation via Thermal Decomposition of N‐Trityl Dihyrdo‐1,2‐Oxazines
Inhaled nitric oxide (iNO) is a promising therapy for a variety of pulmonary conditions but is limited by the cost, portability, and safety limitations of the compressed gas cylinders used in convent...
onlinelibrary.wiley.com
February 3, 2025 at 3:48 PM
The @jrbour.bsky.social Lab establishes a potential chemical basis for a low-power, small-footprint inhaled nitric oxide (iNO) delivery system. @angewandtechemie.bsky.social. #wsuchemistry #ResearchInDetroit #ChemSky
onlinelibrary.wiley.com/doi/10.1002/...
onlinelibrary.wiley.com/doi/10.1002/...
Reposted by Jason Withorn
SAVE THE DATE ‼️ 📆 📢
BBM 2025 will be held on June 9-10th at the Harvard Science Center feat. the one and only Dr. Petra Levin as keynote! We can't wait to see you there.
Registration and scholarship applications open next week.
BBM 2025 will be held on June 9-10th at the Harvard Science Center feat. the one and only Dr. Petra Levin as keynote! We can't wait to see you there.
Registration and scholarship applications open next week.
February 1, 2025 at 3:05 PM
SAVE THE DATE ‼️ 📆 📢
BBM 2025 will be held on June 9-10th at the Harvard Science Center feat. the one and only Dr. Petra Levin as keynote! We can't wait to see you there.
Registration and scholarship applications open next week.
BBM 2025 will be held on June 9-10th at the Harvard Science Center feat. the one and only Dr. Petra Levin as keynote! We can't wait to see you there.
Registration and scholarship applications open next week.
Reposted by Jason Withorn
I am looking for a research associate - a recent college grad with BS or equivalent. Apply online!
searchjobs.dartmouth.edu/postings/77394
searchjobs.dartmouth.edu/postings/77394
Laboratory Technician III
To set up and conduct a variety of laboratory tests and experiments by applying established methods, procedures, and techniques in support of research studies directed at understanding bacterial biofi...
searchjobs.dartmouth.edu
January 29, 2025 at 9:58 PM
I am looking for a research associate - a recent college grad with BS or equivalent. Apply online!
searchjobs.dartmouth.edu/postings/77394
searchjobs.dartmouth.edu/postings/77394
Reposted by Jason Withorn
A new direction for research in the lab around carbon sequestration!
irving.dartmouth.edu/news/2025/01...
irving.dartmouth.edu/news/2025/01...
Two Professors Receive $100,000 Pilot Grant to Enhance Understanding
Two Dartmouth faculty members have been awarded a $100,000 pilot grant to deepen our understanding of the role of marine microbes in carbon sequestration.
irving.dartmouth.edu
January 20, 2025 at 7:33 PM
A new direction for research in the lab around carbon sequestration!
irving.dartmouth.edu/news/2025/01...
irving.dartmouth.edu/news/2025/01...
Last week our NIH T32 Chem Bio Training Program (CBTP) had our biannual retreat here at @stonybrooku.bsky.social
Resume workshops, poster sessions, meetings with the external advisory committee.
Busy week, glad to be back in the lab!
Resume workshops, poster sessions, meetings with the external advisory committee.
Busy week, glad to be back in the lab!
January 13, 2025 at 2:48 PM
Last week our NIH T32 Chem Bio Training Program (CBTP) had our biannual retreat here at @stonybrooku.bsky.social
Resume workshops, poster sessions, meetings with the external advisory committee.
Busy week, glad to be back in the lab!
Resume workshops, poster sessions, meetings with the external advisory committee.
Busy week, glad to be back in the lab!
Cool work to come out of @stonybrooku.bsky.social Pharm (J. Seeliger Lab)!
Lia was my “Big Sib” through our NIH T32 program here. Definetly worth giving it a read!
Lia was my “Big Sib” through our NIH T32 program here. Definetly worth giving it a read!
Metabolic tagging reveals surface-associated lipoproteins in mycobacteria https://www.biorxiv.org/content/10.1101/2025.01.07.631728v1
January 9, 2025 at 3:39 AM
Cool work to come out of @stonybrooku.bsky.social Pharm (J. Seeliger Lab)!
Lia was my “Big Sib” through our NIH T32 program here. Definetly worth giving it a read!
Lia was my “Big Sib” through our NIH T32 program here. Definetly worth giving it a read!
Proud Mentor Alert 🚨
Natalie Osorio, a high school student I had the pleasure of mentoring this summer through @stonybrooku.bsky.social Simons Stem Scholars Program, advanced to the next stage of the Regeneron Talent Search!
Fingers crossed 🤞🏻 Super proud regardless!
Natalie Osorio, a high school student I had the pleasure of mentoring this summer through @stonybrooku.bsky.social Simons Stem Scholars Program, advanced to the next stage of the Regeneron Talent Search!
Fingers crossed 🤞🏻 Super proud regardless!
January 8, 2025 at 9:48 PM
Proud Mentor Alert 🚨
Natalie Osorio, a high school student I had the pleasure of mentoring this summer through @stonybrooku.bsky.social Simons Stem Scholars Program, advanced to the next stage of the Regeneron Talent Search!
Fingers crossed 🤞🏻 Super proud regardless!
Natalie Osorio, a high school student I had the pleasure of mentoring this summer through @stonybrooku.bsky.social Simons Stem Scholars Program, advanced to the next stage of the Regeneron Talent Search!
Fingers crossed 🤞🏻 Super proud regardless!
A nice little biofilm contamination for @contamclub.bsky.social. Popped up on a stack of LB plates left on the bench top. Love to see the wrinkles!
January 7, 2025 at 9:32 PM
A nice little biofilm contamination for @contamclub.bsky.social. Popped up on a stack of LB plates left on the bench top. Love to see the wrinkles!
Reposted by Jason Withorn
Cool #T6SS work by the @basler-lab.bsky.social
Intraspecies competition and the role of multiple T6SS machines
Check at journals.asm.org/doi/epub/10....
Intraspecies competition and the role of multiple T6SS machines
Check at journals.asm.org/doi/epub/10....
December 11, 2024 at 12:36 AM
Cool #T6SS work by the @basler-lab.bsky.social
Intraspecies competition and the role of multiple T6SS machines
Check at journals.asm.org/doi/epub/10....
Intraspecies competition and the role of multiple T6SS machines
Check at journals.asm.org/doi/epub/10....
Man oh man is today one of those days where lab is finding new ways to make me go 🙃
December 10, 2024 at 5:07 PM
Man oh man is today one of those days where lab is finding new ways to make me go 🙃
Reposted by Jason Withorn
Very elegant work by Matt Parsek and Dan Wozniak crew. See the @pnas.org paper by Zheng et al at doi.org/10.1073/pnas...
The surface matters when it comes to trigger Pseudomonas aeruginosa signalling through cdiGMP or cAMP
The surface matters when it comes to trigger Pseudomonas aeruginosa signalling through cdiGMP or cAMP
December 8, 2024 at 2:21 PM
Very elegant work by Matt Parsek and Dan Wozniak crew. See the @pnas.org paper by Zheng et al at doi.org/10.1073/pnas...
The surface matters when it comes to trigger Pseudomonas aeruginosa signalling through cdiGMP or cAMP
The surface matters when it comes to trigger Pseudomonas aeruginosa signalling through cdiGMP or cAMP
Reposted by Jason Withorn
On Fri Dec 13 15:00-17:00 CET join @krastevalab.bsky.social, George O'Toole, and me for the @asm.org Sweden Finland Lecture series 2024 mini-symposium on #biofilm and #c-di-GMP signaling!
#microsky🦠🧫
Zoom ki-se.zoom.us/j/6761509723...
#microsky🦠🧫
Zoom ki-se.zoom.us/j/6761509723...
December 9, 2024 at 9:14 AM
On Fri Dec 13 15:00-17:00 CET join @krastevalab.bsky.social, George O'Toole, and me for the @asm.org Sweden Finland Lecture series 2024 mini-symposium on #biofilm and #c-di-GMP signaling!
#microsky🦠🧫
Zoom ki-se.zoom.us/j/6761509723...
#microsky🦠🧫
Zoom ki-se.zoom.us/j/6761509723...