Sjoerd Wanrooij
@wanrooij20.bsky.social
Group Leader at Umeå University | Researching mitochondrial biology with a focus on mtDNA | Investigating the cellular functions of G-quadruplex DNA structures
Reposted by Sjoerd Wanrooij
Travelling to the future again. This thursday, we will be nosy and learn about mitochondria and their friendships.
February 10, 2026 at 11:07 PM
Travelling to the future again. This thursday, we will be nosy and learn about mitochondria and their friendships.
Reposted by Sjoerd Wanrooij
Tomorrow. See you there?
Thinking about remodeling? Mitochondria do that too... and our speaker knows all about it.
This thursday, usual time and place.
See you there?
This thursday, usual time and place.
See you there?
February 4, 2026 at 11:45 AM
Tomorrow. See you there?
Reposted by Sjoerd Wanrooij
Thinking about remodeling? Mitochondria do that too... and our speaker knows all about it.
This thursday, usual time and place.
See you there?
This thursday, usual time and place.
See you there?
February 2, 2026 at 11:32 AM
Thinking about remodeling? Mitochondria do that too... and our speaker knows all about it.
This thursday, usual time and place.
See you there?
This thursday, usual time and place.
See you there?
Reposted by Sjoerd Wanrooij
5 years of MITOtalks!
Feels like it was yesterday when @wanrooij20.bsky.social
and @nunoraimundo.bsky.social
opened the first MITOtalk to introduce
@frezzalab.bsky.social.
But it turns out FIVE YEARS have passed. That's 57 MITOtalks, 44 MITOchats, 6000+ followers.
Onwards and upwards!
Feels like it was yesterday when @wanrooij20.bsky.social
and @nunoraimundo.bsky.social
opened the first MITOtalk to introduce
@frezzalab.bsky.social.
But it turns out FIVE YEARS have passed. That's 57 MITOtalks, 44 MITOchats, 6000+ followers.
Onwards and upwards!
January 21, 2026 at 4:50 PM
5 years of MITOtalks!
Feels like it was yesterday when @wanrooij20.bsky.social
and @nunoraimundo.bsky.social
opened the first MITOtalk to introduce
@frezzalab.bsky.social.
But it turns out FIVE YEARS have passed. That's 57 MITOtalks, 44 MITOchats, 6000+ followers.
Onwards and upwards!
Feels like it was yesterday when @wanrooij20.bsky.social
and @nunoraimundo.bsky.social
opened the first MITOtalk to introduce
@frezzalab.bsky.social.
But it turns out FIVE YEARS have passed. That's 57 MITOtalks, 44 MITOchats, 6000+ followers.
Onwards and upwards!
Reposted by Sjoerd Wanrooij
The MITOscience of tomorrow is back.
Three short mitochats presented by
Débora Santos Rocha @deborasrocha.bsky.social ,
Valentin L’Hôte @valentinlhote.bsky.social and
Marijana Croon @marijanacroon.bsky.social
Visit mitotalks.org for zoom link details.
Will you time travel with us?
Three short mitochats presented by
Débora Santos Rocha @deborasrocha.bsky.social ,
Valentin L’Hôte @valentinlhote.bsky.social and
Marijana Croon @marijanacroon.bsky.social
Visit mitotalks.org for zoom link details.
Will you time travel with us?
January 14, 2026 at 3:14 PM
The MITOscience of tomorrow is back.
Three short mitochats presented by
Débora Santos Rocha @deborasrocha.bsky.social ,
Valentin L’Hôte @valentinlhote.bsky.social and
Marijana Croon @marijanacroon.bsky.social
Visit mitotalks.org for zoom link details.
Will you time travel with us?
Three short mitochats presented by
Débora Santos Rocha @deborasrocha.bsky.social ,
Valentin L’Hôte @valentinlhote.bsky.social and
Marijana Croon @marijanacroon.bsky.social
Visit mitotalks.org for zoom link details.
Will you time travel with us?
Reposted by Sjoerd Wanrooij
In case you overloaded mitochondria and peroxisomes during your holidays, know that they are talking about it... and our speaker Peter Kim overheard the conversation.
This thursday, usual time and place. See you there?
This thursday, usual time and place. See you there?
January 6, 2026 at 5:23 PM
In case you overloaded mitochondria and peroxisomes during your holidays, know that they are talking about it... and our speaker Peter Kim overheard the conversation.
This thursday, usual time and place. See you there?
This thursday, usual time and place. See you there?
Reposted by Sjoerd Wanrooij
MITOchats are all about early career researchers and - of course - mitochondria! Join us tomorrow for three short talks delivered by Julia Riley @joulesriley.bsky.social, Eleonora Stronati, and Joan Blanco-Fernandez @joanblanco.bsky.social. See mitotalks.org for zoom link.
December 10, 2025 at 7:49 PM
MITOchats are all about early career researchers and - of course - mitochondria! Join us tomorrow for three short talks delivered by Julia Riley @joulesriley.bsky.social, Eleonora Stronati, and Joan Blanco-Fernandez @joanblanco.bsky.social. See mitotalks.org for zoom link.
Reposted by Sjoerd Wanrooij
the MITOscience of tomorrow is back.
December 9, 2025 at 9:53 AM
the MITOscience of tomorrow is back.
Reposted by Sjoerd Wanrooij
Last MitoTALK of 2025!
Ewa Warczak
@bomba_ewa
From Synthesis to Stability: Understanding the Lifecycle of Mitochondrial Proteins
Thursday, December 4, usual time.
See you there?
mitotalks.org
Ewa Warczak
@bomba_ewa
From Synthesis to Stability: Understanding the Lifecycle of Mitochondrial Proteins
Thursday, December 4, usual time.
See you there?
mitotalks.org
December 4, 2025 at 1:07 AM
Last MitoTALK of 2025!
Ewa Warczak
@bomba_ewa
From Synthesis to Stability: Understanding the Lifecycle of Mitochondrial Proteins
Thursday, December 4, usual time.
See you there?
mitotalks.org
Ewa Warczak
@bomba_ewa
From Synthesis to Stability: Understanding the Lifecycle of Mitochondrial Proteins
Thursday, December 4, usual time.
See you there?
mitotalks.org
Reposted by Sjoerd Wanrooij
Thanks for coming, Björn!
🔬 MedChem Seminar Series
Today we welcomed Björn Forsberg (Linköping University) for an excellent talk:
“Methods for Quantified Feature Detection in Cryo-EM Reconstructions.”
👉 More on Björn's research: liu.se/en/employee/...
📅 More seminars: www.umu.se/en/departmen...
#CryoEM #StructuralBiology
Today we welcomed Björn Forsberg (Linköping University) for an excellent talk:
“Methods for Quantified Feature Detection in Cryo-EM Reconstructions.”
👉 More on Björn's research: liu.se/en/employee/...
📅 More seminars: www.umu.se/en/departmen...
#CryoEM #StructuralBiology
Björn Forsberg
Structural bioinformatics studies biology through data. We develop and use new tools to study cryo-EM reconstructions and data to understand molecular life.
liu.se
November 18, 2025 at 3:35 PM
Thanks for coming, Björn!
Reposted by Sjoerd Wanrooij
We’re live!
The Department of Medical Biochemistry & Biophysics at @umeauniversitet.bsky.social explores life at the molecular level: infection and structural biology, gene expression, mitochondria, neurodegeneration & biophysics for climate change.
Follow for updates & collaboration!
#Biochemistry
The Department of Medical Biochemistry & Biophysics at @umeauniversitet.bsky.social explores life at the molecular level: infection and structural biology, gene expression, mitochondria, neurodegeneration & biophysics for climate change.
Follow for updates & collaboration!
#Biochemistry
November 13, 2025 at 9:59 AM
We’re live!
The Department of Medical Biochemistry & Biophysics at @umeauniversitet.bsky.social explores life at the molecular level: infection and structural biology, gene expression, mitochondria, neurodegeneration & biophysics for climate change.
Follow for updates & collaboration!
#Biochemistry
The Department of Medical Biochemistry & Biophysics at @umeauniversitet.bsky.social explores life at the molecular level: infection and structural biology, gene expression, mitochondria, neurodegeneration & biophysics for climate change.
Follow for updates & collaboration!
#Biochemistry
Reposted by Sjoerd Wanrooij
How's your juggling act? Mitochondria also have one, and the MITOtalk this week will be all about it.
See you there?
See you there?
November 4, 2025 at 2:11 PM
How's your juggling act? Mitochondria also have one, and the MITOtalk this week will be all about it.
See you there?
See you there?
Reposted by Sjoerd Wanrooij
Our new preprint is out 🥳🥳🥳
Henipaviruses, like Nipah and Hendra, package their genomes inside helical shells built by thousands of nucleoproteins. These nucleocapsids are essential to protect the viral RNA, but how do they ever let the polymerase in to read the sequence?
👇
Henipaviruses, like Nipah and Hendra, package their genomes inside helical shells built by thousands of nucleoproteins. These nucleocapsids are essential to protect the viral RNA, but how do they ever let the polymerase in to read the sequence?
👇
November 3, 2025 at 12:26 PM
Our new preprint is out 🥳🥳🥳
Henipaviruses, like Nipah and Hendra, package their genomes inside helical shells built by thousands of nucleoproteins. These nucleocapsids are essential to protect the viral RNA, but how do they ever let the polymerase in to read the sequence?
👇
Henipaviruses, like Nipah and Hendra, package their genomes inside helical shells built by thousands of nucleoproteins. These nucleocapsids are essential to protect the viral RNA, but how do they ever let the polymerase in to read the sequence?
👇
Reposted by Sjoerd Wanrooij
🚨 Postdoc position open!
Join us at Umeå University to study proteins that maintain mitochondrial DNA stability.
2-year fellowship | International research environment | Apply now!
🔗 umustipendie.varbi.com/en/what:job/...
#Postdoc #Mitochondria #Biochemistry #AcademicJobs
Join us at Umeå University to study proteins that maintain mitochondrial DNA stability.
2-year fellowship | International research environment | Apply now!
🔗 umustipendie.varbi.com/en/what:job/...
#Postdoc #Mitochondria #Biochemistry #AcademicJobs
Postdoctoral fellowship (2 years) to study proteins that maintain mitochondrial DNA
The Department of Medical Biochemistry and Biophysics is offering a postdoctoral scholarship within the project "Signaling of mitochondrial DNA instability". The scholarship is full-time for two year
umustipendie.varbi.com
October 22, 2025 at 11:20 AM
🚨 Postdoc position open!
Join us at Umeå University to study proteins that maintain mitochondrial DNA stability.
2-year fellowship | International research environment | Apply now!
🔗 umustipendie.varbi.com/en/what:job/...
#Postdoc #Mitochondria #Biochemistry #AcademicJobs
Join us at Umeå University to study proteins that maintain mitochondrial DNA stability.
2-year fellowship | International research environment | Apply now!
🔗 umustipendie.varbi.com/en/what:job/...
#Postdoc #Mitochondria #Biochemistry #AcademicJobs
Reposted by Sjoerd Wanrooij
Who wouldn't want a good workout for their mitochondria to be fit?? Learn with our speaker Kostas Tokatlidis how to get them fit!
We would tell you the time and place, but you know where to find this MITOtalk on October 2nd. Right?
We would tell you the time and place, but you know where to find this MITOtalk on October 2nd. Right?
September 30, 2025 at 3:22 PM
Who wouldn't want a good workout for their mitochondria to be fit?? Learn with our speaker Kostas Tokatlidis how to get them fit!
We would tell you the time and place, but you know where to find this MITOtalk on October 2nd. Right?
We would tell you the time and place, but you know where to find this MITOtalk on October 2nd. Right?
Reposted by Sjoerd Wanrooij
The future is visiting again! We are seeking applicants for the 7th season of MITOchats. Deadline for submission is October 17th. Visit www.mitotalks.org for details or submit your application at forms.gle/5D6vWE92yYCi...
September 25, 2025 at 9:59 PM
The future is visiting again! We are seeking applicants for the 7th season of MITOchats. Deadline for submission is October 17th. Visit www.mitotalks.org for details or submit your application at forms.gle/5D6vWE92yYCi...
Reposted by Sjoerd Wanrooij
(2/2) And from January 2026 onwards:
Jan 08 Peter Kim
Feb 05 Robin Klemm
March 05 Natalie Niemi
April 02 Henry Higgs
May 07 Eija Pirinen
June 04 Heidi McBride
usual time and place. See you there?
Jan 08 Peter Kim
Feb 05 Robin Klemm
March 05 Natalie Niemi
April 02 Henry Higgs
May 07 Eija Pirinen
June 04 Heidi McBride
usual time and place. See you there?
September 9, 2025 at 5:07 PM
(2/2) And from January 2026 onwards:
Jan 08 Peter Kim
Feb 05 Robin Klemm
March 05 Natalie Niemi
April 02 Henry Higgs
May 07 Eija Pirinen
June 04 Heidi McBride
usual time and place. See you there?
Jan 08 Peter Kim
Feb 05 Robin Klemm
March 05 Natalie Niemi
April 02 Henry Higgs
May 07 Eija Pirinen
June 04 Heidi McBride
usual time and place. See you there?
Reposted by Sjoerd Wanrooij
Now that the summer season is over, it's time for some MITObusiness. (1/2)
Oct 02 Kostas Tokatlidis
Nov 06 Hiromi Sesaki
Dec 04 Ewa Bomba-Warczak
Oct 02 Kostas Tokatlidis
Nov 06 Hiromi Sesaki
Dec 04 Ewa Bomba-Warczak
September 9, 2025 at 5:07 PM
Now that the summer season is over, it's time for some MITObusiness. (1/2)
Oct 02 Kostas Tokatlidis
Nov 06 Hiromi Sesaki
Dec 04 Ewa Bomba-Warczak
Oct 02 Kostas Tokatlidis
Nov 06 Hiromi Sesaki
Dec 04 Ewa Bomba-Warczak
Reposted by Sjoerd Wanrooij
Today!!! See you there?
Join us tomorrow (3 July) for our webinar with @mitotalks.bsky.social showcasing research from our recent Special Issue: Cell Biology of Mitochondria.
🗓️Thursday 3 July 2025, 16:00 BST
Register here: us02web.zoom.us/webinar/regi...
#webinar #mitochondria #cellbio
🗓️Thursday 3 July 2025, 16:00 BST
Register here: us02web.zoom.us/webinar/regi...
#webinar #mitochondria #cellbio
July 3, 2025 at 1:26 PM
Today!!! See you there?
Reposted by Sjoerd Wanrooij
📢One week to go until our webinar with @mitotalks.bsky.social focussed on all things #mitochondria.
Register here: us02web.zoom.us/webinar/regi...
Register here: us02web.zoom.us/webinar/regi...
June 26, 2025 at 2:25 PM
📢One week to go until our webinar with @mitotalks.bsky.social focussed on all things #mitochondria.
Register here: us02web.zoom.us/webinar/regi...
Register here: us02web.zoom.us/webinar/regi...
Reposted by Sjoerd Wanrooij
Our next #FocalPlaneFeatures webinar is in collaboration with @mitotalks.bsky.social. For this special webinar, Nuno Raimundo & @wanrooij20.bsky.social have selected 3 talks from @jcellsci.bsky.social's Special Issue: Cell Biology of Mitochondria.
📅3 July
focalplane.biologists.com/2025/06/09/m...
📅3 July
focalplane.biologists.com/2025/06/09/m...
June 9, 2025 at 2:47 PM
Our next #FocalPlaneFeatures webinar is in collaboration with @mitotalks.bsky.social. For this special webinar, Nuno Raimundo & @wanrooij20.bsky.social have selected 3 talks from @jcellsci.bsky.social's Special Issue: Cell Biology of Mitochondria.
📅3 July
focalplane.biologists.com/2025/06/09/m...
📅3 July
focalplane.biologists.com/2025/06/09/m...
Reposted by Sjoerd Wanrooij
Our newest paper on mitochondrial Topoisomerase 1 shows that Top1mt has only weak endoribonuclease activity and it therefore does not often generate deletions at incorporated ribonucleotides. This helps explain why ribonucleotides are tolerated in mtDNA. Read more:
academic.oup.com/nar/article-...
academic.oup.com/nar/article-...
The low endoribonuclease activity and lack of rNMP preference of human mitochondrial topoisomerase 1 protect against ribonucleotide-dependent deletions
Abstract. The incorporation of ribonucleotides (rNMPs) into the nuclear genome leads to severe genomic instability, including strand breaks and short 2–5 b
academic.oup.com
June 8, 2025 at 11:31 AM
Our newest paper on mitochondrial Topoisomerase 1 shows that Top1mt has only weak endoribonuclease activity and it therefore does not often generate deletions at incorporated ribonucleotides. This helps explain why ribonucleotides are tolerated in mtDNA. Read more:
academic.oup.com/nar/article-...
academic.oup.com/nar/article-...
Reposted by Sjoerd Wanrooij
MITOtalks and especially MITOchats have been playing with time travel. This week, instead of bringing the future over, we will get there faster: our speaker will tell us all about a mitochondrial progeria syndrome. Usual time and place.
June 4, 2025 at 2:38 PM
MITOtalks and especially MITOchats have been playing with time travel. This week, instead of bringing the future over, we will get there faster: our speaker will tell us all about a mitochondrial progeria syndrome. Usual time and place.
Reposted by Sjoerd Wanrooij
This thursday, we talk supply logistics, with lots of energy.
May 6, 2025 at 6:36 PM
This thursday, we talk supply logistics, with lots of energy.
Reposted by Sjoerd Wanrooij
Two mtDNA papers of ours in one PNAS issue:
#1 on the Y951N patient mutation of PolG, heroically spear-headed by Josefin Forslund
#2 revealing surprising dNTP imbalance & subsequent mtDNA depletion in RRM2B-deficient mice, a great collaboration with the Chabes lab
www.pnas.org/toc/pnas/122...
#1 on the Y951N patient mutation of PolG, heroically spear-headed by Josefin Forslund
#2 revealing surprising dNTP imbalance & subsequent mtDNA depletion in RRM2B-deficient mice, a great collaboration with the Chabes lab
www.pnas.org/toc/pnas/122...
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
www.pnas.org
April 22, 2025 at 6:41 PM
Two mtDNA papers of ours in one PNAS issue:
#1 on the Y951N patient mutation of PolG, heroically spear-headed by Josefin Forslund
#2 revealing surprising dNTP imbalance & subsequent mtDNA depletion in RRM2B-deficient mice, a great collaboration with the Chabes lab
www.pnas.org/toc/pnas/122...
#1 on the Y951N patient mutation of PolG, heroically spear-headed by Josefin Forslund
#2 revealing surprising dNTP imbalance & subsequent mtDNA depletion in RRM2B-deficient mice, a great collaboration with the Chabes lab
www.pnas.org/toc/pnas/122...