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varianteffect.bsky.social
Atlas of Variant Effects Alliance
@varianteffect.bsky.social
560 followers 200 following 120 posts
Advancing the promise of the Human Genome Project by interpreting the landscape of human genetic variation.
https://www.varianteffect.org
https://www.linkedin.com/company/atlas-of-variant-effects-alliance
Posts Replies Media Videos
Reposted by Atlas of Variant Effects Alliance
muffley.bsky.social
Join us for a special @varianteffect.bsky.social Fireside Chat on Jan 6th, 2026 (9-10am Pacific) w/ @maitreya.bsky.social (@uwgenome.bsky.social) & @mehurles.bsky.social (@sangerinstitute.bsky.social)

Visit www.varianteffect.org/event/firesi...
for more info and to add this event to your calendar
The image is a promotional graphic for a "Fireside Chat" event organized by the Variant Effects Seminar Series and the AVE Alliance. The background is light gray, and the text is in dark gray and green. At the top, there is a stylized image of a fireplace with flames. Below, bold text reads "Fireside Chat," with an invitation to join on January 6th, 2026, featuring Dr. Maitreya Dunham and Dr. Matthew Hurles discussing MAVEs in clinical space and model organism systems. The date and time are highlighted in dark and light green ovals: "01.06.26" and "9:00AM (Pacific)." To the right, the Atlas of Variant Effects logo is displayed featuring stylized DNA strands formed by interwoven lines. At the bottom, there are two photos: on the left is Dr. Maitreya Dunham, with the text "Maitreya Dunham, University of Washington," and on the right is Dr. Matthew Hurles, with the text "Matthew Hurles, Wellcome Sanger Institute."
November 10, 2025 at 2:30 PM
varianteffect.bsky.social
Coming up!
Rewriting Cancer’s Script:
Insights from Saturation Genome Editing
🗓️ 25 November 2025 4 PM CET | 7 AM PST
@twistbioscience.com #Webinar
with @davidjadams.bsky.social @sangerinstitute.bsky.social
Register for this free webinar here:
tinyurl.com/RewritingCan...
November 10, 2025 at 2:34 PM
varianteffect.bsky.social
If you are planning to attend the Mutational Scanning Symposium next year in Melbourne, we recommend that you register as soon as possible to secure your spot!
🗓️ March 25-27, 2026
➡️ Register now
📝 Submit your abstract
🇦🇺 Apply for your Visa
🛫 Book your flight
ℹ️ ➡️ www.mss2026.org
#VariantEffect26
November 10, 2025 at 2:24 PM
Reposted by Atlas of Variant Effects Alliance
jingyour.bsky.social
🎙️ Next up Dec 2 in VESS!

Thea Schulze (Lindorff-Larsen Lab): Predicting mutated protein abundance @tkschulze.bsky.social

Taylor Mighell (Lehner Lab): Massive mutagenesis to understand GPCRs @taylor-mighell.bsky.social

🔗 More info at varianteffect.org/seminar-series
@varianteffect.bsky.social
November 4, 2025 at 6:31 PM
varianteffect.bsky.social
2026 Mutational Scanning Symposium & Workshop will be here before you know it! Register now to secure your spot and get a ticket 🎟️ for the conference dinner at Melbourne Museum! 🦕 tinyurl.com/MSS26Registr... #VariantEffect26 #Dinosaurs #RegisterNow
November 4, 2025 at 3:11 PM
varianteffect.bsky.social
🗓️Abstract Deadline Extended
to December 1st, 2025!
#VariantEffect26
ℹ️https://www.mss2026.org
November 3, 2025 at 2:30 PM
varianteffect.bsky.social
Coming up next week!
Free! No registration required!
ℹ️ www.varianteffect.org/seminar-seri...
October 31, 2025 at 9:24 PM
varianteffect.bsky.social
We have an incredible speaker line-up for next years Mutational Scanning Symposium 🤩. Register now and submit your abstract before the deadline next week!
ℹ️ www.mss2026.org
#VariantEffect26 #FOMO #Functional #Genomics #Symposium #Abstract #Deadline
October 31, 2025 at 2:11 PM
varianteffect.bsky.social
brotmanbaty.org/news/q-and-a... @brotmanbaty.bsky.social Q&A with #VariantEffect26 co-organizer Rehan Villani.
October 17, 2025 at 6:10 PM
varianteffect.bsky.social
Join us for the 9th Annual Mutational Scanning Symposium! #VariantEffect26
When: March 25-27, 2026
Where: Melbourne, Australia (and online!)
Be sure to submit your abstract by Nov 2nd 2025
ℹ️https://www.mss2026.org
October 16, 2025 at 2:21 PM
varianteffect.bsky.social
We are #Hiring! Note the close date of tomorrow October 14th!
sangerinstitute.bsky.social Wellcome Sanger Institute @sangerinstitute.bsky.social · Oct 2
This role, based at Sanger, will lead on the communications for the Atlas of Variant Effects Alliance - an initiative that is mapping the effects of all the possible variants of human genes 🧬

This is a part-time role, closing on 14th Oct.
More info ⤵️
sanger.wd103.myworkdayjobs.com/WellcomeSang...
October 13, 2025 at 7:40 PM
varianteffect.bsky.social
📣 We are #Hiring
🌟 Scientific Communications Manager -Part Time
🔹 Communications role for our Global Alliance!
🔹 Hinxton, Cambridgeshire UK and hybrid
🔹 Part-time
🔹 Closing on Oct. 14th (TOMORROW!)
➡️https://tinyurl.com/CommunicationsJob
@sangerinstitute.bsky.social
#ScienceJobs #Communications
October 13, 2025 at 7:26 PM
varianteffect.bsky.social
Be sure to check out our monthly Seminar Series!

🔹Upcoming speakers www.varianteffect.org/seminar-seri...

🔹Previous speakers www.varianteffect.org/previous-sem...

#Seminar #Series #Science #FunctionalGenomics
The image depicts an illustration of three people engaged in a virtual seminar setup. In the center, a large computer monitor displays a person in a green shirt, speaking and gesturing with their right hand. The screen includes a "LIVE" label and various digital interface elements. On the left, a person wearing a red shirt and headphones sits at a desk, using a laptop. On the right, another person with glasses and headphones is seated in a cross-legged position, holding a laptop. Surrounding elements include a bookshelf, a clock, a chat bubble, and a potted plant. The background is a light gray color with abstract shapes. In brief: Illustration of three people participating in a virtual seminar, with a large monitor, laptops, and digital interface elements. Illustration by pikisuperstar (Freepik)
October 11, 2025 at 2:16 PM
Reposted by Atlas of Variant Effects Alliance
kroman.bsky.social
🎥 My Variant Effects Seminar Series (VESS) talk is now on YouTube! I discuss how DropSynth-based gene synthesis reveals how bacterial DHFR variants evolve antibiotic resistance. Thanks to @varianteffect.bsky.social for the invite!

🔗 www.youtube.com/watch?v=KiA9...

#VESS #VariantEffects #DropSynth
"Large-scale synthetic gene libraries for decoding variant effects in antibiotic resistance"
YouTube video by Variant Effects
www.youtube.com
October 10, 2025 at 11:26 PM
Reposted by Atlas of Variant Effects Alliance
jingyour.bsky.social
Coming up next in the VESS (Nov 4):

Population genetics × variant effects:

🧬 Nikhil Milind (Stanford) on gene dosage and complex traits @nikhilmilind.dev
🧬 Leslie Smith (U Florida) on equitable ML in cancer genomics

www.varianteffect.org/seminar-seri...
@varianteffect.bsky.social
October 10, 2025 at 2:43 PM
varianteffect.bsky.social
🌏 🧬 Join the global functional genomics community in Melbourne this March for MSS26! The 9th Annual Mutational Scanning Symposium #VariantEffect26 runs March 25–27, 2026 at the Aikenhead Centre for Medical Discovery.
🗓️ Early bird registration & abstract submissions close Nov 2, 2025.
www.mss2026.org
MSS26
Mutational Scanning Symposium 2026, 25-27 March, Melbourne
www.mss2026.org
October 10, 2025 at 2:40 PM
varianteffect.bsky.social
🌟 Scientific Communications Manager -Part Time
📣 We are #Hiring
🔹 Communications role for our Global Alliance!
🔹 Hinxton, Cambridgeshire UK and hybrid
🔹 Part-time
🔹 Closing on Oct. 14th

Learn more and apply!
@sangerinstitute.bsky.social

www.linkedin.com/posts/atlas-...
Scientific Communications Manager -Part Time | Atlas of Variant Effects Alliance
🌟 Scientific Communications Manager -Part Time 📣 We are #Hiring and we'd love to have you on our team! 🔹 Communications role for our Global Alliance! 🔹 Hinxton, Cambridgeshire UK and hybrid 🔹 Part-t...
www.linkedin.com
October 10, 2025 at 2:39 PM
varianteffect.bsky.social
🌏 🧬 Join the global functional genomics community in Melbourne this March for MSS26! The 9th Annual Mutational Scanning Symposium #VariantEffect26 runs March 25–27, 2026 at the Aikenhead Centre for Medical Discovery.
Abstract submissions are open and will close 2 November 2025. www.mss2026.org
October 8, 2025 at 2:37 PM
varianteffect.bsky.social
Variant Effects Seminar Series
October and November lineup! Join us!
ℹ️https://www.varianteffect.org/seminar-series/
October 3, 2025 at 1:50 PM
Reposted by Atlas of Variant Effects Alliance
sangerinstitute.bsky.social
This role, based at Sanger, will lead on the communications for the Atlas of Variant Effects Alliance - an initiative that is mapping the effects of all the possible variants of human genes 🧬

This is a part-time role, closing on 14th Oct.
More info ⤵️
sanger.wd103.myworkdayjobs.com/WellcomeSang...
October 2, 2025 at 10:25 AM
Reposted by Atlas of Variant Effects Alliance
ee-reh-neh.bsky.social
I'm stoked to be organising next year's MSS right here in beautiful Melbourne! We know Australia is very far away, and we're working hard to make sure we can support as many ECRs to attend as possible, so please do register and apply for a travel award!
varianteffect.bsky.social Atlas of Variant Effects Alliance @varianteffect.bsky.social · Sep 26
📣Call for Abstracts
for the Mutational Scanning Symposium! #VariantEffect26
🗓️ March 25-27, 2026
📍 Melbourne, Australia (and online!)
📝 Submit your abstract (deadline is Nov 2nd, 2025!)
➡️ Registration is also now open!!
ℹ️ www.mss2026.org

#FunctionalGenomics #Symposium #Australia #CallForAbstracts
October 2, 2025 at 1:47 AM
varianteffect.bsky.social
We are #Hiring!
Communications role for our Global Alliance! 🌍🧬
Please share this post with your network, or apply if you are interested!
📍 Location: Hinxton, England
🕒 Part-time role
ℹ️ sanger.wd103.myworkdayjobs.com/en-US/Wellco...

#ScienceJobs #Communications #Genomics
#PartTimeRole #UKJobs
October 1, 2025 at 1:52 PM
varianteffect.bsky.social
We are hiring! Communications role for our Global Alliance! sanger.wd103.myworkdayjobs.com/en-US/Wellco... #job #hiring #Communications Hinxton, Cambridgeshire UK
Scientific Communications Manager -Part Time
Do you want to help us improve human health and understand life on Earth? Make your mark by shaping the future to enable or deliver life-changing science to solve some of humanity’s greatest challenge...
sanger.wd103.myworkdayjobs.com
September 30, 2025 at 7:57 PM
varianteffect.bsky.social
📣Call for Abstracts
for the Mutational Scanning Symposium! #VariantEffect26
🗓️ March 25-27, 2026
📍 Melbourne, Australia (and online!)
📝 Submit your abstract (deadline is Nov 2nd, 2025!)
➡️ Registration is also now open!!
ℹ️ www.mss2026.org

#FunctionalGenomics #Symposium #Australia #CallForAbstracts
September 26, 2025 at 1:52 PM
varianteffect.bsky.social
🧬 Out this month in Nature Reviews Cardiology: A powerful look at how multiplexed assays of variant effects (MAVEs) are reshaping our understanding of cardiovascular disease genetics. Contributors include members of the AVE Alliance.
📑 www.nature.com/articles/s41...
#Cardiology #FunctionalGenomics
Creating an atlas of variant effects to resolve variants of uncertain significance and guide cardiovascular medicine - Nature Reviews Cardiology
In this Review, Roden and co-workers describe how multiplexed assays of variant effects can be used for high-throughput functional assessment of nearly all coding variants in a target sequence to impr...
www.nature.com
September 19, 2025 at 1:04 PM