Victor Ambros
LightNews LightNews
vambros.bsky.social
Victor Ambros
@vambros.bsky.social
560 followers 26 following 55 posts
Biologist; Umass Chan Medical School
Posts Replies Media Videos
vambros.bsky.social
Very cool!
November 29, 2025 at 12:00 AM
vambros.bsky.social
pubmed.ncbi.nlm.nih.gov/41237758/ A thought-provoking perspective on animal development and tissue homeostasis.
Bridging single cells to organs: Mesoscale modules as fundamental units of tissue function - PubMed
Recent studies at molecular and genomic scales have enriched our understanding of life's most fundamental building block: the cell. However, bridging the gap between single-cell phenotypes and the emergent functions of tissues and organs remains a formidable challenge. Here, we suggest that the conc …
pubmed.ncbi.nlm.nih.gov
November 28, 2025 at 2:30 PM
Reposted by Victor Ambros
pnas.org
One of the most-viewed PNAS articles in the last week is “Neurodevelopmental disorder–linked Argonaute mutations permit delayed RISC formation and unusual shortening of miRNAs by 3′→5′ trimming.” Explore now: https://ow.ly/hwP450XxHM6

For more trending articles, visit https://ow.ly/q6Cl50XxHGN.
AGO1(ΔF180) retains the ability to form functionally mature RISCs.
November 25, 2025 at 10:00 PM
Reposted by Victor Ambros
pnas.org
All hail Caenorhabditis elegans, one of the most researched organisms on Earth. Collaborative data sharing in the nematode research community led to four Nobel Prize-winning discoveries about human development and disease. In PNAS: https://ow.ly/uNqU50Xyj4e
Caenorhabditis elegans, imaged with confocal laser scanning microscopy, and modeled by surface rendering software. Stock image.
November 26, 2025 at 7:01 PM
vambros.bsky.social
Where did he get that? Did he just make it up? (Does anyone know what is ‘Mortality Match’, indicated by the logo at upper left?) Sweden’s excess death rate was far greater than any of its neighbors in 2020 but got much better in 2021, presumably owing to vaccination among other factors.
jeremymberg.bsky.social Jeremy Berg @jeremymberg.bsky.social · Nov 24
Direktör Bhattacharya: Som forskare, när du ser negativa överdödsfall som börjar under ett allvarligt sjukdomsutbrott, får det dig att ifrågasätta antagandena i din modell?

1/2
An X post from NIH Director Bhattacharya showing substantial negative excess deaths in Sweden from 2000 to 2004.
November 25, 2025 at 1:01 PM
Reposted by Victor Ambros
umasschan.bsky.social
The Cure Alzheimer’s Fund has awarded Dorothy P. Schafer, PhD, more than $400,000 in funding over two years for her project studying ependymal cells and their potential connection to Alzheimer’s disease: direc.to/oamk

#Alzheimers #AlzheimersDisease @curealzheimersfund.bsky.social
Dorothy P. Schafer, PhD
November 24, 2025 at 2:57 PM
Reposted by Victor Ambros
odedrechavi.bsky.social
Read this inspiring perspectives coauthored by the Worm Resource directors and worm Nobel Laureates! 4 Nobel Prizes and how they were enabled by major NIH-supported research resources (the Caenorhabditis Genetics Center, WormBase, and WormAtlas) www.pnas.org/doi/10.1073/...
November 25, 2025 at 6:18 AM
Reposted by Victor Ambros
nature.com
Nature research paper: ZAK activation at the collided ribosome

go.nature.com/4a9cika
ZAK activation at the collided ribosome - Nature
The kinase ZAK is activated at collided ribosomes to mediate the ribotoxic stress response.
go.nature.com
November 25, 2025 at 10:56 AM
Reposted by Victor Ambros
mendell-lab.bsky.social
Regulated decay of microRNAs plays a critical role in controlling body size in mammals! Check out our new paper in @genesdev.bsky.social and see thread previously posted with our pre-print 👇 for more info. Congrats to Collette LaVigne, Jaeil Han, and all authors!
genesdev.cshlp.org/cgi/content/...
November 10, 2025 at 5:40 PM
vambros.bsky.social
www.statnews.com/2025/10/21/h...
The U.S. experiment with profit-driven health care has failed
“The market competition, managed care, and ‘corporate efficiency’ that economists prescribed as the cure for health care inflation instead accelerated it.”
www.statnews.com
October 22, 2025 at 11:30 AM
vambros.bsky.social
Droplet outbursts from onion cutting | PNAS www.pnas.org/doi/10.1073/...
Droplet outbursts from onion cutting | PNAS
Cutting onions often leads to tear-inducing aerosol release, yet the underlying mechanics remain poorly understood. In this work, via high-speed ch...
www.pnas.org
October 21, 2025 at 5:19 PM
vambros.bsky.social
Paul Simon's "Surprise". Produced by Brian Emo
odedrechavi.bsky.social Oded Rechavi @odedrechavi.bsky.social · Oct 20
I'm on a plane and I want to listen to a whole album, not just individual songs (old school!) - which album do you recommend?
October 20, 2025 at 3:40 PM
vambros.bsky.social
An excellent piece by Joachim Frank, 2017 Nobel Laureate in Chemistry, about how we must resist the Trump Administration's crackdown on universities.

www.usnews.com/opinion/arti...
www.usnews.com
October 12, 2025 at 3:47 PM
Reposted by Victor Ambros
pehjackson.bsky.social
UVA Faculty Senate passed a resolution strongly opposing the Trump “Compact.” We, at least, remain committed to the historic values and mission of the university.
Resolution Opposing the "Compact for Academic Excellence in Higher Education" WHEREAS the United States Secretary of Education has requested that the University of Virginia enter into a “Compact for Academic Excellence in Higher Education”, and WHEREAS the Compact contains provisions antithetical to the mission and traditions of the University, and WHEREAS the Compact contains provisions which endanger the independence and integrity of the University, and WHEREAS the compact likely violates state and federal law, and infringes upon the constitutional rights of members of the University community, and WHEREAS the University of Virginia exemplifies American academic values of the highest standard, including universal right to free speech and the cultivation of academic freedom; therefore BE IT RESOLVED that the Faculty Senate of the University of Virginia firmly opposes this Compact as written and calls upon Interim President Mahoney and the Board of Visitors to also reject this Compact outright as well as any similar proposal compromising the mission, values, and independence of the University.
October 3, 2025 at 9:51 PM
vambros.bsky.social
Are you an alum from one of the 9 schools Trump just attacked? Sign this alumni petition now to support your school, defend democracy, and build a grassroots movement for campus freedom across America. alumni.controlshift.app/petitions/tr...
STAND WITH YOUR SCHOOL: Trump attacks 9 universities. Sign the alumni petition now.
Are you an alum from one of the 9 schools Trump just attacked? Sign this alumni petition now to support your school, defend democracy, and build a grassroots movement for campus freedom across America...
alumni.controlshift.app
October 4, 2025 at 2:47 PM
vambros.bsky.social
Rachael, This is funny …. But is it real? Was the video posted by Trump? … No ! …. but … was it? …. No …. (!) … (?) Am I going nuts?
docsirianni.bsky.social Rachael Sirianni, PhD @docsirianni.bsky.social · Oct 3
Yes but also amidst this <surreal nightmare that is the collapse of our formerly free society> - and really gimme a break for a bit of humor bc it’s 24/7 misery at the moment - all I can think about this video is “More Cowbell” and I REALLY hope Christopher Walken has something to say about this
gtconway.bsky.social George Conway ⚖️🇺🇸 @gtconway.bsky.social · Oct 3
Signs of psychosis. No biggie
October 4, 2025 at 2:44 PM
Reposted by Victor Ambros
biologists.bsky.social
You can read Mark's 2024 @dev-journal.bsky.social Review article here: doi.org/10.1242/dev....
40 years since the Heidelberg genetic screen that revolutionized developmental and cell biology
ABSTRACT. Our current understanding of the molecular basis of embryonic development and the shared machinery underlying this remarkable process has its roots in three papers published 40 years ago, wh...
doi.org
October 3, 2025 at 4:13 PM
Reposted by Victor Ambros
cdelawalla.bsky.social
Our officials statement on the Compact.
standupforscience.bsky.social Stand Up for Science! @standupforscience.bsky.social · Oct 2
READ ⬇️ Stand Up For Science Statement on Compact Corrupting Higher Education.
10/2/2025: Stand Up For Science Statement on Compact Corrupting Higher Education. Washington, D.C. — Today, the administration has unveiled their proposed "compact" for higher education. This document is antithetical to the free academic inquiry that forms the foundation of American excellence in higher education. Further, while the compact is framed as a way to promote fairness in higher education, this compact runs counter to the scientific method by prioritizing federal grant funding to go to universities who have signed, rather than proposals that have been selected by experts. We call on university leaders to unite and reject this overreach of executive power by the White House. The compact lies in the context of an ongoing and multi-pronged attack on the integrity of the American scientific ecosystem, but this also tangibly represents the President seizing control of public spaces and higher education. Each university represents a beacon of free thought, vibrant educational empowerment, and public enrichment, and we must demand President Trump stay out of dictating universities. "Trump's compact is yet another form of attack on the American institutions that provide evidence that counter's the core belief of MAGA — racism, misogyny, and regression of the human race to name a few. If universities agree to these terms, academic freedom in America will be over," says Colette Delawalla Founder and Director of Stand Up For Science. She continues "when the White House takes over what is defined as 'truth' regardless of scientific evidence, we are no longer in a free nation. Universities must understanding the seriousness of this moment and respond accordingly." Stand Up For Science will reliably sound the alarm when science and scientists are under attack, and our platform empowers scientists to speak out and organize against corruption of American science. The proposing of this document represents an extreme authoritarian escalation for American higher education. It is crucial that university leaders, congress and the public stand together to protect higher education from this attack.
October 2, 2025 at 6:06 PM
Reposted by Victor Ambros
docsirianni.bsky.social
I am not a political pawn. I am a living, breathing human being who has dedicated her life to a scientific problem that I believe matters for human health. The article below tells our story; I hope you will read it and share it www.nytimes.com/2025/09/14/m...
Trump Is Shutting Down the War On Cancer
www.nytimes.com
September 14, 2025 at 2:26 PM
Reposted by Victor Ambros
jeremymberg.bsky.social
Powerful new article in NYT Magazine on cancer research

[Gift Link]

www.nytimes.com/2025/09/14/m...
Trump Is Shutting Down the War On Cancer
www.nytimes.com
September 14, 2025 at 5:15 PM
vambros.bsky.social
Went for a run, lovely voice of Patty Scialfa in my ears, the singer-songwriter’s gorgeous album, ‘Rumble Doll’ — my favorite solo album by a member of the E Street Band (other than Bruce).
September 9, 2025 at 9:50 PM
Reposted by Victor Ambros
neuroscinikolai.bsky.social
Been having a lot of fun lately listening to the Night Science Podcast after stumbling on it from the article series by @itaiyanai.bsky.social and Martin Lercher, definitely recommend it if you have a passing interest in the creative aspects of how the scientific process is conducted 😄
September 8, 2025 at 7:55 AM
vambros.bsky.social
Sad to hear that David Baltimore died. I am one of hundreds of scientists that David generously mentored, supported, and inspired. His influence on each of us was deep and lasting, and his impact on the world immeasurable. Arguably David Baltimore is one of the greatest scientists of any generation.
September 7, 2025 at 9:50 PM
vambros.bsky.social
fb.watch/BX4G9O8w8t/?
fb.watch
September 5, 2025 at 9:42 PM
vambros.bsky.social
“A scheduler for rhythmic gene expression”
Gaidatzis, Graf-Landua, Woelk, Brancati, Hauser, Meeuse, Nahar, Braun, van der Does, Aluri, Kohler, Smallwood and Helge Grosshans
bioRxiv. 4 September 2025, , 10.1101/2025.09.04.674194
biorxiv.org/content/earl...
September 5, 2025 at 11:13 AM