Tyler Kent
@tylervkent.bsky.social
Postdoc @ University of Chicago Ecology & Evolution
Evolutionary genomics mostly
Evolutionary genomics mostly
Reposted by Tyler Kent
Congrats @jeffgroh.bsky.social et al. Some avocado trees open female-phase flowers in the morning & then male in afternoon. Others show complementary pattern (m->f), to synchronize pollination of two types. Jeff show this to be a >45Mya polymorphism at a transcription factor across 100s of species.
Balanced polymorphism in a floral transcription factor underlies an ancient rhythm of daily sex alternation in avocado https://www.biorxiv.org/content/10.64898/2025.12.22.695989v1
December 25, 2025 at 6:47 PM
Congrats @jeffgroh.bsky.social et al. Some avocado trees open female-phase flowers in the morning & then male in afternoon. Others show complementary pattern (m->f), to synchronize pollination of two types. Jeff show this to be a >45Mya polymorphism at a transcription factor across 100s of species.
Reposted by Tyler Kent
Do extra chromosome sets mask bad mutations? Simulations show tetraploids often carry higher genetic load than diploids, depending on dominance, demography, and drift—with important implications for fitness and conservation.
academic.oup.com/evlett/artic...
academic.oup.com/evlett/artic...
The hidden threat: genetic load dynamics in tetraploids and diploids
Polyploid organisms often display unique evolutionary dynamics compared to diploids. One unresolved question is how polyploidy affects the accumulation of
academic.oup.com
December 18, 2025 at 12:59 PM
Do extra chromosome sets mask bad mutations? Simulations show tetraploids often carry higher genetic load than diploids, depending on dominance, demography, and drift—with important implications for fitness and conservation.
academic.oup.com/evlett/artic...
academic.oup.com/evlett/artic...
Reposted by Tyler Kent
🧬 Just out in Bioinformatics Advances: “tskit arg visualizer: Interactive plotting of ancestral recombination graphs.”
Read the full paper here: https://doi.org/10.1093/bioadv/vbaf302
Authors include: @kitchensjn.bsky.social, @yanwong.bsky.social
Read the full paper here: https://doi.org/10.1093/bioadv/vbaf302
Authors include: @kitchensjn.bsky.social, @yanwong.bsky.social
December 18, 2025 at 10:02 AM
🧬 Just out in Bioinformatics Advances: “tskit arg visualizer: Interactive plotting of ancestral recombination graphs.”
Read the full paper here: https://doi.org/10.1093/bioadv/vbaf302
Authors include: @kitchensjn.bsky.social, @yanwong.bsky.social
Read the full paper here: https://doi.org/10.1093/bioadv/vbaf302
Authors include: @kitchensjn.bsky.social, @yanwong.bsky.social
Reposted by Tyler Kent
Now out! How important is social experience in male mating behavior? @corrallopeza.bsky.social found that experienced males were more likely to coerce non-receptive females, but did not change overall preference onlinelibrary.wiley.com/doi/10.1002/... w/ @vdbijl.bsky.social @idarolti.bsky.social
December 11, 2025 at 3:47 PM
Now out! How important is social experience in male mating behavior? @corrallopeza.bsky.social found that experienced males were more likely to coerce non-receptive females, but did not change overall preference onlinelibrary.wiley.com/doi/10.1002/... w/ @vdbijl.bsky.social @idarolti.bsky.social
Reposted by Tyler Kent
I am currently searching for a new postdoctoral researcher to study the evolution, genetics, and physiology of cold acclimation and freezing tolerance in switchgrass at Michigan State University. This work will be funded by a newly funded five-year DOE grant. careers.msu.edu/jobs/researc...
Research Associate-Fixed Term - East Lansing, Michigan, United States
Position Summary
The Lowry Lab at Michigan State University is searching for a postdoctoral research associate to conduct molecular and physiological experiments to understand the causes of genetic va...
careers.msu.edu
November 20, 2025 at 2:50 PM
I am currently searching for a new postdoctoral researcher to study the evolution, genetics, and physiology of cold acclimation and freezing tolerance in switchgrass at Michigan State University. This work will be funded by a newly funded five-year DOE grant. careers.msu.edu/jobs/researc...
Reposted by Tyler Kent
We have TWO post-doctoral fellowships in the Biodiversity Centre at UBC next year! Am happy to chat if you might want to be hosted in my lab. biodiversity.ubc.ca/training-and... Deadline January 15th!
November 3, 2025 at 5:16 PM
We have TWO post-doctoral fellowships in the Biodiversity Centre at UBC next year! Am happy to chat if you might want to be hosted in my lab. biodiversity.ubc.ca/training-and... Deadline January 15th!
Reposted by Tyler Kent
Elevated mutation near crossovers inhibits the evolution of recombination https://www.biorxiv.org/content/10.1101/2025.11.01.685904v1
November 2, 2025 at 3:32 AM
Elevated mutation near crossovers inhibits the evolution of recombination https://www.biorxiv.org/content/10.1101/2025.11.01.685904v1
Reposted by Tyler Kent
Great to see that our mosquito cell atlas is now out in Cell. Amazing work from @oliviagoldman.net and @nadavshai.bsky.social to organise so much data and so many interesting stories into a single paper!
Excited to announce the final version of the Mosquito Cell Atlas is out now in @cellpress.bsky.social!! 🦟🩸
There is SO much left to find & investigate in this dataset (& the rich biology of the Aedes aegypti mosquito)! We hope this helps scientists in many fields!
www.cell.com/cell/fulltex...
There is SO much left to find & investigate in this dataset (& the rich biology of the Aedes aegypti mosquito)! We hope this helps scientists in many fields!
www.cell.com/cell/fulltex...
A single-nucleus transcriptomic atlas of the adult Aedes aegypti mosquito
A comprehensive single-nucleus RNA-seq atlas of >367,000 nuclei from male and female
Aedes aegypti mosquitoes reveals sexual dimorphism in sensory systems and brain cell
types and widespread co-expres...
www.cell.com
October 30, 2025 at 8:52 PM
Great to see that our mosquito cell atlas is now out in Cell. Amazing work from @oliviagoldman.net and @nadavshai.bsky.social to organise so much data and so many interesting stories into a single paper!
Reposted by Tyler Kent
The Johri Lab has an open postdoc position. Please send me an email, if interested. Start date is flexible. Please do share! Thank you in advance.
October 28, 2025 at 9:31 PM
The Johri Lab has an open postdoc position. Please send me an email, if interested. Start date is flexible. Please do share! Thank you in advance.
Reposted by Tyler Kent
The Hopkins Lab (hopkins-lab.com) at the University of Florida is looking to recruit a postdoc to work on the genetics of organ function and evolution across Drosophila and beyond. Please visit tinyurl.com/vcsjpmzz or email me for more info. And please RT or send to anyone who might be interested!
October 15, 2025 at 8:42 PM
The Hopkins Lab (hopkins-lab.com) at the University of Florida is looking to recruit a postdoc to work on the genetics of organ function and evolution across Drosophila and beyond. Please visit tinyurl.com/vcsjpmzz or email me for more info. And please RT or send to anyone who might be interested!
Reposted by Tyler Kent
Hey Yaniv Brandvain is not on Bluesky but his most recent biostats ebook is live ybrandvain.github.io/biostats/. His stats resources have been so helpful to me as I develop my own stats course, so check it out. Github repo here: github.com/ybrandvain/b...
Applied Biostatistics
ybrandvain.github.io
October 24, 2025 at 2:47 PM
Hey Yaniv Brandvain is not on Bluesky but his most recent biostats ebook is live ybrandvain.github.io/biostats/. His stats resources have been so helpful to me as I develop my own stats course, so check it out. Github repo here: github.com/ybrandvain/b...
Reposted by Tyler Kent
Separating selection from mutation in antibody language models https://www.biorxiv.org/content/10.1101/2025.10.21.683652v1
October 22, 2025 at 8:32 PM
Separating selection from mutation in antibody language models https://www.biorxiv.org/content/10.1101/2025.10.21.683652v1
Reposted by Tyler Kent
The Genomic Architecture of Local Adaptation in Two Connected Populations of Three-Spined Stickleback. https://www.biorxiv.org/content/10.1101/2025.10.21.683682v1
October 22, 2025 at 6:32 PM
The Genomic Architecture of Local Adaptation in Two Connected Populations of Three-Spined Stickleback. https://www.biorxiv.org/content/10.1101/2025.10.21.683682v1
Reposted by Tyler Kent
Reposted by Tyler Kent
One of the most exciting works of my career, years in the making. We used high-throughput precision genome editing to test the fitness effects of thousands of natural variants. Our findings challenge the long-held assumption that common variants are inconsequential.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Massively parallel interrogation of the fitness of natural variants in ancient signaling pathways reveals pervasive local adaptation
The nature of standing genetic variation remains a central debate in population genetics, with differing perspectives on whether common variants are almost always neutral as suggested by neutral and n...
www.biorxiv.org
October 22, 2025 at 5:46 PM
One of the most exciting works of my career, years in the making. We used high-throughput precision genome editing to test the fitness effects of thousands of natural variants. Our findings challenge the long-held assumption that common variants are inconsequential.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Tyler Kent
In a new paper led by Jiaqi Yang we trace the distribution of Denisovan introgressed DNA in ancient modern human genomes over time.
www.cell.com/current-biol...
www.cell.com/current-biol...
An early East Asian lineage with unexpectedly low Denisovan ancestry
Yang et al. study Denisovan ancestry in ancient and present-day humans. In contrast
to other East Asians, genomic comparisons suggest that the Jomon derived most of their
ancestry from a deep lineage ...
www.cell.com
October 20, 2025 at 7:39 PM
In a new paper led by Jiaqi Yang we trace the distribution of Denisovan introgressed DNA in ancient modern human genomes over time.
www.cell.com/current-biol...
www.cell.com/current-biol...
Reposted by Tyler Kent
We're excited to be recruiting an NIH funded postdoc to work in the Coop lab at UC Davis. We're specifically interested in candidates who are want to work at the intersection of human genetics, GWAS, and population genetics modeling. Please RT
October 15, 2025 at 3:53 PM
We're excited to be recruiting an NIH funded postdoc to work in the Coop lab at UC Davis. We're specifically interested in candidates who are want to work at the intersection of human genetics, GWAS, and population genetics modeling. Please RT
Reposted by Tyler Kent
#PhD Position: Interested in the evolutionary and ecological impacts of whole genome duplication?
Join Dr. Tia-Lynn Ashman @drtialynn.bsky.social
and I at the U. of Pittsburgh, to test what drives the competitive outcomes between diploids and #polyploids
Details: shorturl.at/nQ8UW
Join Dr. Tia-Lynn Ashman @drtialynn.bsky.social
and I at the U. of Pittsburgh, to test what drives the competitive outcomes between diploids and #polyploids
Details: shorturl.at/nQ8UW
October 20, 2025 at 4:17 PM
#PhD Position: Interested in the evolutionary and ecological impacts of whole genome duplication?
Join Dr. Tia-Lynn Ashman @drtialynn.bsky.social
and I at the U. of Pittsburgh, to test what drives the competitive outcomes between diploids and #polyploids
Details: shorturl.at/nQ8UW
Join Dr. Tia-Lynn Ashman @drtialynn.bsky.social
and I at the U. of Pittsburgh, to test what drives the competitive outcomes between diploids and #polyploids
Details: shorturl.at/nQ8UW
Reposted by Tyler Kent
Sharing our new paper, "Distinct haplotypes and reversed dominance at a single-gene balanced polymorphism controlling heterodichogamy in two genera of wingnuts". Genomics & evolution of a mating type system involving two morphs with alternating sexes in walnut relatives www.cell.com/current-biol...
Distinct haplotypes and reversed dominance at a single-gene balanced polymorphism controlling heterodichogamy in two genera of wingnuts
In most species within the walnut family, two genetically determined morphs alternate
between male and female flowering phases in time. Groh et al. identify a distinct
locus for this dimorphism in two...
www.cell.com
October 16, 2025 at 3:43 PM
Sharing our new paper, "Distinct haplotypes and reversed dominance at a single-gene balanced polymorphism controlling heterodichogamy in two genera of wingnuts". Genomics & evolution of a mating type system involving two morphs with alternating sexes in walnut relatives www.cell.com/current-biol...
Reposted by Tyler Kent
Now available in Systematic Biology, a new paper (and R package) in which we outline an approach to account for non-independence in comparative analyses of lineage-pair traits academic.oup.com/sysbio/advan...
The Comparative Analysis of Lineage-Pair Traits
Abstract. For many questions in ecology and evolution, the most relevant data to consider are attributes of lineage pairs. Comparative tests for causal rel
academic.oup.com
October 13, 2025 at 6:46 PM
Now available in Systematic Biology, a new paper (and R package) in which we outline an approach to account for non-independence in comparative analyses of lineage-pair traits academic.oup.com/sysbio/advan...
Reposted by Tyler Kent
I am hiring a postdoc to examine the genomic and evolutionary basis of plant microbiome variation in legumes. There are opportunities to gain teaching experience. Chicago is a great city to live in! Please help spread the word.
share.google/gukbzS1zdIx6...
share.google/gukbzS1zdIx6...
Postdoctoral Researcher in Plant Evolutionary Genomics
The postdoctoral researcher will work in Dr. Michael Grillo’s plant evolutionary genetics lab. The goal of this research project is to understand the genomic basis of plant-microbiome variation in leg...
share.google
October 10, 2025 at 6:11 PM
I am hiring a postdoc to examine the genomic and evolutionary basis of plant microbiome variation in legumes. There are opportunities to gain teaching experience. Chicago is a great city to live in! Please help spread the word.
share.google/gukbzS1zdIx6...
share.google/gukbzS1zdIx6...
Reposted by Tyler Kent
For “Reflections on the history of modeling and theory”, @sarperotto.bsky.social and I met with Joel Cohen. We learn how he navigated math and biology, the value of embracing ignorance, and what is a population. Or really, what _isn't_ a population: www.youtube.com/watch?v=RCt9...
@smtpb.bsky.social
@smtpb.bsky.social
Reflections on Modeling and Theory in Population Biology: Joel Cohen
YouTube video by SMTPB
www.youtube.com
June 26, 2025 at 3:31 PM
For “Reflections on the history of modeling and theory”, @sarperotto.bsky.social and I met with Joel Cohen. We learn how he navigated math and biology, the value of embracing ignorance, and what is a population. Or really, what _isn't_ a population: www.youtube.com/watch?v=RCt9...
@smtpb.bsky.social
@smtpb.bsky.social
Reposted by Tyler Kent
New preprint led by grad student, Yu Mo! We introduce new software to calculate evolutionary rates of quantitative characters in the presence of discordance
1/
www.biorxiv.org/content/10.1...
1/
www.biorxiv.org/content/10.1...
Estimating the rate of quantitative trait evolution in the presence of gene tree discordance by calculating likelihoods across trees
Quantitative traits provide insights into how phenotypes evolve across species. However, standard comparative methods often assume a single species tree and overlook the discordant gene tree histories...
www.biorxiv.org
October 7, 2025 at 3:10 PM
New preprint led by grad student, Yu Mo! We introduce new software to calculate evolutionary rates of quantitative characters in the presence of discordance
1/
www.biorxiv.org/content/10.1...
1/
www.biorxiv.org/content/10.1...
Reposted by Tyler Kent
New paper by former MSc student @christeinecke.bsky.social! ⭐ A behemoth effort to apply artificial selection on clonal reproduction in #Mimulus guttatus. We show that clonality evolves quickly, but not symmetrically in both directions, and multivariate life history traits are altered too! 🧪🌾
Life-history evolution under artificial selection in a clonal plant https://www.biorxiv.org/content/10.1101/2025.10.01.679824v1
October 2, 2025 at 11:50 AM
New paper by former MSc student @christeinecke.bsky.social! ⭐ A behemoth effort to apply artificial selection on clonal reproduction in #Mimulus guttatus. We show that clonality evolves quickly, but not symmetrically in both directions, and multivariate life history traits are altered too! 🧪🌾
Reposted by Tyler Kent
Human-mediated land-use and climate change occur simultaneously, but how do they interact to shape adaptive dynamics? Super excited to share the first paper from the Kreiner lab, led by postdoc extraordinaire @rpineau.bsky.social
October 6, 2025 at 3:13 PM
Human-mediated land-use and climate change occur simultaneously, but how do they interact to shape adaptive dynamics? Super excited to share the first paper from the Kreiner lab, led by postdoc extraordinaire @rpineau.bsky.social