This trial aimed to provide estimates of effect and feasibility of a physical activity intervention for hospitalized cancer survivors using smartwatches for goal-setting and feedback.

Purpose To evaluate the effectiveness of an evidence-based pre-, peri- and postoperative rehabilitation pathway (i.e. the REACT rehabilitation pathway) on disability in patients undergoing lumbar fusi...

Objective To investigate cost-effectiveness of pre-discharge home assessment visits for patients recovering after hip fracture. Design Cost-effectiveness analys...

Background Hospital-acquired deconditioning is a term used in clinical practice, describing a loss of physical and/or cognitive function associated with hospitalisation. Previous reviews have addresse...

AbstractBackground. There is relatively low uptake of remote monitoring on frailty virtual wards (Hospital at Home) compared to virtual wards caring for pe

Background Shoulder osteoarthritis is a common cause of pain, disability and difficulty sleeping. Patient information leaflets are produced by NHS Trusts with the aim of informing patients about the...

Reliable, well conducted and adequately reported research is essential for decision-making. This study uses an exploratory clustering approach to identify patterns (subgroups) of trials based on research conduct and reporting characteristics to better understand heterogeneity. Describing features of these subgroups may help elucidate mechanisms of poor planning and reporting that can be acted upon by the research community to improve the research practices. Estimating the impact of trials from specific subgroup classes on pooled treatment effects and overall certainty of evidence may inform conduct and interpretation of systematic reviews in the future.

In September 2024, WHO published its groundbreaking guidance on best practices for clinical trials - establishing, for the first time, a global framework applicable to the design and conduct of all cl...