Miloš Tišma
@tismaa.bsky.social
Biology is life 🌱 Biophysics is a tool
Postdoc at Harvard Medical School | Joe Loparo Lab
PhD at TU Delft | Cees Dekker Lab
Postdoc at Harvard Medical School | Joe Loparo Lab
PhD at TU Delft | Cees Dekker Lab
Reposted by Miloš Tišma
Wow, what an honor!
The @biophysicalsoc.bsky.social awards me the esteemed '2026 Kazuhiko Kinosita Award in Single-Molecule Biophysics'
'for groundbreaking contributions to the field of nanobiology and single-molecule biophysics, from nanopores to SMC molecular motors'.
Feel honored, very thankful!
The @biophysicalsoc.bsky.social awards me the esteemed '2026 Kazuhiko Kinosita Award in Single-Molecule Biophysics'
'for groundbreaking contributions to the field of nanobiology and single-molecule biophysics, from nanopores to SMC molecular motors'.
Feel honored, very thankful!
September 23, 2025 at 9:05 PM
Wow, what an honor!
The @biophysicalsoc.bsky.social awards me the esteemed '2026 Kazuhiko Kinosita Award in Single-Molecule Biophysics'
'for groundbreaking contributions to the field of nanobiology and single-molecule biophysics, from nanopores to SMC molecular motors'.
Feel honored, very thankful!
The @biophysicalsoc.bsky.social awards me the esteemed '2026 Kazuhiko Kinosita Award in Single-Molecule Biophysics'
'for groundbreaking contributions to the field of nanobiology and single-molecule biophysics, from nanopores to SMC molecular motors'.
Feel honored, very thankful!
Absolutely preposterous size of a Giant Sequoia…
August 8, 2025 at 4:49 PM
Absolutely preposterous size of a Giant Sequoia…
Reposted by Miloš Tišma
Here's a new very exciting paper from our #CDlab: www.cell.com/cell-reports...
In an exemplary in vitro/in vivo study, 1st authors @btanalikwu.bsky.social & Alice Deshayes showed that dense linear protein arrays (e.g. telomeres) do stop loop-extruding SMCs!
Great collaboration with Marcand lab.
In an exemplary in vitro/in vivo study, 1st authors @btanalikwu.bsky.social & Alice Deshayes showed that dense linear protein arrays (e.g. telomeres) do stop loop-extruding SMCs!
Great collaboration with Marcand lab.
June 25, 2025 at 6:59 AM
Here's a new very exciting paper from our #CDlab: www.cell.com/cell-reports...
In an exemplary in vitro/in vivo study, 1st authors @btanalikwu.bsky.social & Alice Deshayes showed that dense linear protein arrays (e.g. telomeres) do stop loop-extruding SMCs!
Great collaboration with Marcand lab.
In an exemplary in vitro/in vivo study, 1st authors @btanalikwu.bsky.social & Alice Deshayes showed that dense linear protein arrays (e.g. telomeres) do stop loop-extruding SMCs!
Great collaboration with Marcand lab.
Wrapped up a GRC on Bacterial Cell Biology and Development last week in SNHU, New Hampshire.
A full week of talks on novel bacterial systems and new mechanistic details on eastablished systems.
Great chance to learn, connect with peers and enjoy science!
A full week of talks on novel bacterial systems and new mechanistic details on eastablished systems.
Great chance to learn, connect with peers and enjoy science!
June 9, 2025 at 2:56 PM
Wrapped up a GRC on Bacterial Cell Biology and Development last week in SNHU, New Hampshire.
A full week of talks on novel bacterial systems and new mechanistic details on eastablished systems.
Great chance to learn, connect with peers and enjoy science!
A full week of talks on novel bacterial systems and new mechanistic details on eastablished systems.
Great chance to learn, connect with peers and enjoy science!
Reposted by Miloš Tišma
We're excited to host two fantastic speakers at our next online @physicsoflifeuk.bsky.social ECR Seminar on Tuesday 15 April, 2–3 PM BST:
Tisma Milos and Thomas McLean
chaired by @veronicabiga.bsky.social
Please register below for the Zoom link:
lnkd.in/dSynrAe8
Tisma Milos and Thomas McLean
chaired by @veronicabiga.bsky.social
Please register below for the Zoom link:
lnkd.in/dSynrAe8
April 10, 2025 at 10:44 AM
We're excited to host two fantastic speakers at our next online @physicsoflifeuk.bsky.social ECR Seminar on Tuesday 15 April, 2–3 PM BST:
Tisma Milos and Thomas McLean
chaired by @veronicabiga.bsky.social
Please register below for the Zoom link:
lnkd.in/dSynrAe8
Tisma Milos and Thomas McLean
chaired by @veronicabiga.bsky.social
Please register below for the Zoom link:
lnkd.in/dSynrAe8
Just watched a podcast with Jiankui He, the first person to go. through with CRISPR editing in human babies in 2018.
He started a complex debate (both in productive and destructive ways) on ethics in science, future of gene editing and safety of current methods.
www.youtube.com/watch?v=ch03...
He started a complex debate (both in productive and destructive ways) on ethics in science, future of gene editing and safety of current methods.
www.youtube.com/watch?v=ch03...
The Man Who Used Gene Editing On Babies - Jiankui He
YouTube video by BioAcc Podcast
www.youtube.com
March 4, 2025 at 2:44 AM
Just watched a podcast with Jiankui He, the first person to go. through with CRISPR editing in human babies in 2018.
He started a complex debate (both in productive and destructive ways) on ethics in science, future of gene editing and safety of current methods.
www.youtube.com/watch?v=ch03...
He started a complex debate (both in productive and destructive ways) on ethics in science, future of gene editing and safety of current methods.
www.youtube.com/watch?v=ch03...
A lovely visit to Yale School of Medicine to see @leoschaerfen.bsky.social graduate with a spectacular PhD work.
🤩
🤩
March 1, 2025 at 11:58 AM
A lovely visit to Yale School of Medicine to see @leoschaerfen.bsky.social graduate with a spectacular PhD work.
🤩
🤩
Biologist-"Let me order some Biotin-11-dUTP"
Chemist-"Let me order some ((2R,3S,5R)-5-(2,4-dioxo-5-(3-(6-(5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)hexanamido)prop-1-yn-1-yl)-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxytetrahydrofuran-2-yl)methyl hydrogen triphosphate"
😅
Chemist-"Let me order some ((2R,3S,5R)-5-(2,4-dioxo-5-(3-(6-(5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)hexanamido)prop-1-yn-1-yl)-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxytetrahydrofuran-2-yl)methyl hydrogen triphosphate"
😅
February 25, 2025 at 7:20 PM
Biologist-"Let me order some Biotin-11-dUTP"
Chemist-"Let me order some ((2R,3S,5R)-5-(2,4-dioxo-5-(3-(6-(5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)hexanamido)prop-1-yn-1-yl)-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxytetrahydrofuran-2-yl)methyl hydrogen triphosphate"
😅
Chemist-"Let me order some ((2R,3S,5R)-5-(2,4-dioxo-5-(3-(6-(5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)hexanamido)prop-1-yn-1-yl)-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxytetrahydrofuran-2-yl)methyl hydrogen triphosphate"
😅
Reposted by Miloš Tišma
Legitmately thrilled to share our latest work, in which @fernpizza.bsky.social solved an experimental challenge in plasmid biology as old as the field: measuring how plasmids compete and evolve within individual cells!
February 21, 2025 at 8:42 PM
Legitmately thrilled to share our latest work, in which @fernpizza.bsky.social solved an experimental challenge in plasmid biology as old as the field: measuring how plasmids compete and evolve within individual cells!
Nice to see that Science(.org) supports and spreads awareness of the massive protests currently ongoing in Serbia!
Peaceful protests lead by Serbian University students (later joined by many others), have gathered more than 200 000 people on occasions!
www.science.org/content/arti...
Peaceful protests lead by Serbian University students (later joined by many others), have gathered more than 200 000 people on occasions!
www.science.org/content/arti...
Scientists rally in support of Serbia’s anticorruption protests
But some criticize “weak and formal” support for protests from scientific institutions
www.science.org
February 13, 2025 at 5:13 PM
Nice to see that Science(.org) supports and spreads awareness of the massive protests currently ongoing in Serbia!
Peaceful protests lead by Serbian University students (later joined by many others), have gathered more than 200 000 people on occasions!
www.science.org/content/arti...
Peaceful protests lead by Serbian University students (later joined by many others), have gathered more than 200 000 people on occasions!
www.science.org/content/arti...
This is so real 🤣🤣
I do not know the explanation of this but definitely resonates very well…
I do not know the explanation of this but definitely resonates very well…
January 30, 2025 at 3:25 AM
This is so real 🤣🤣
I do not know the explanation of this but definitely resonates very well…
I do not know the explanation of this but definitely resonates very well…
Reposted by Miloš Tišma
What is the multiscale structure of chromatin condensates? How does it shape thermodynamic and material properties?
We address this at near-atomistic resolution🔥🔥🔥 using cryoET (Rosen & Villa labs, led by H Zhou), a new multiscale model (K Russell) and cryoET-guided sims (J Huertas & J Maristany)
We address this at near-atomistic resolution🔥🔥🔥 using cryoET (Rosen & Villa labs, led by H Zhou), a new multiscale model (K Russell) and cryoET-guided sims (J Huertas & J Maristany)
January 23, 2025 at 9:32 AM
What is the multiscale structure of chromatin condensates? How does it shape thermodynamic and material properties?
We address this at near-atomistic resolution🔥🔥🔥 using cryoET (Rosen & Villa labs, led by H Zhou), a new multiscale model (K Russell) and cryoET-guided sims (J Huertas & J Maristany)
We address this at near-atomistic resolution🔥🔥🔥 using cryoET (Rosen & Villa labs, led by H Zhou), a new multiscale model (K Russell) and cryoET-guided sims (J Huertas & J Maristany)
Reposted by Miloš Tišma
Congrats to #CDlab graduate Miloš Tišma for winning a Rubicon grant to pursue postdoc research on antibiotic resistance at Harvard Medical School!
Glad to receive the trust and recognition in being awarded a Dutch NWO Rubicon Fellowship for important work on antibiotic resistance.
I will be tackling this problem using a combination of biophysics, biochemistry and microbiology in Joe Loparo lab at Harvard Medical School (Dept. of BCMP).
I will be tackling this problem using a combination of biophysics, biochemistry and microbiology in Joe Loparo lab at Harvard Medical School (Dept. of BCMP).
January 23, 2025 at 11:08 AM
Congrats to #CDlab graduate Miloš Tišma for winning a Rubicon grant to pursue postdoc research on antibiotic resistance at Harvard Medical School!
Glad to receive the trust and recognition in being awarded a Dutch NWO Rubicon Fellowship for important work on antibiotic resistance.
I will be tackling this problem using a combination of biophysics, biochemistry and microbiology in Joe Loparo lab at Harvard Medical School (Dept. of BCMP).
I will be tackling this problem using a combination of biophysics, biochemistry and microbiology in Joe Loparo lab at Harvard Medical School (Dept. of BCMP).
January 15, 2025 at 3:49 PM
Glad to receive the trust and recognition in being awarded a Dutch NWO Rubicon Fellowship for important work on antibiotic resistance.
I will be tackling this problem using a combination of biophysics, biochemistry and microbiology in Joe Loparo lab at Harvard Medical School (Dept. of BCMP).
I will be tackling this problem using a combination of biophysics, biochemistry and microbiology in Joe Loparo lab at Harvard Medical School (Dept. of BCMP).
Reposted by Miloš Tišma
About the price of a hefty GPU workstation, close to a student’s annual consumables cost in the lab, attendence to 5 conferences, full week of Krios data collection, cost of ~100 samples for proteomics data collection… so many things to better spend the money than these outrageous publishing fees.
oefff, paying 11253 euro as open access fee for publishing a single paper in Cell (@cp-cell.bsky.social) - that's an outrageous amount of money.
December 19, 2024 at 12:35 PM
About the price of a hefty GPU workstation, close to a student’s annual consumables cost in the lab, attendence to 5 conferences, full week of Krios data collection, cost of ~100 samples for proteomics data collection… so many things to better spend the money than these outrageous publishing fees.
Reposted by Miloš Tišma
The truth is nobody should care how many protein coding genes there are. The gene is a useful abstraction that loses its utility when defined precisely enough to count.
Exactly how many protein-coding genes are there in the human genome? The truth is no one knows. The numbers change based on what database you use as reference.
December 15, 2024 at 3:46 PM
The truth is nobody should care how many protein coding genes there are. The gene is a useful abstraction that loses its utility when defined precisely enough to count.
Reposted by Miloš Tišma
This will be me in a few months when i come back @btanalikwu.bsky.social and Jaco 🤣🙈
Revisiting the lab where you did your post doc and meeting your bench mates who're still there
November 30, 2024 at 4:09 AM
This will be me in a few months when i come back @btanalikwu.bsky.social and Jaco 🤣🙈
I hope this can inspire and motivate someone that distances that are often expected to happen as you walk your path through science, do not have to be harmful to your relationships and friendships ☺️
Nice to be featured in @natureportfolio.bsky.social Career Column for our personal story on how we kept in touch over the years.
From undergrad -> MSc -> PhDs and beyond
We added science to our friendships and in turn our friendships to our science!
doi: doi.org/10.1038/d415...
From undergrad -> MSc -> PhDs and beyond
We added science to our friendships and in turn our friendships to our science!
doi: doi.org/10.1038/d415...
Raising a glass to the Four Friends Doing Science journal club
Four researchers who left Serbia to pursue their careers rely on this group to keep in touch and to navigate life in science.
doi.org
November 28, 2024 at 5:18 PM
I hope this can inspire and motivate someone that distances that are often expected to happen as you walk your path through science, do not have to be harmful to your relationships and friendships ☺️
Nice to be featured in @natureportfolio.bsky.social Career Column for our personal story on how we kept in touch over the years.
From undergrad -> MSc -> PhDs and beyond
We added science to our friendships and in turn our friendships to our science!
doi: doi.org/10.1038/d415...
From undergrad -> MSc -> PhDs and beyond
We added science to our friendships and in turn our friendships to our science!
doi: doi.org/10.1038/d415...
Raising a glass to the Four Friends Doing Science journal club
Four researchers who left Serbia to pursue their careers rely on this group to keep in touch and to navigate life in science.
doi.org
November 28, 2024 at 5:16 PM
Nice to be featured in @natureportfolio.bsky.social Career Column for our personal story on how we kept in touch over the years.
From undergrad -> MSc -> PhDs and beyond
We added science to our friendships and in turn our friendships to our science!
doi: doi.org/10.1038/d415...
From undergrad -> MSc -> PhDs and beyond
We added science to our friendships and in turn our friendships to our science!
doi: doi.org/10.1038/d415...
Out today in Nucleic Acids Research! My final publication from @ceesdekker.bsky.social lab together with A.M. Gonzalez !
Together with @gruberlab.bsky.social in Lausanne, we show the interaction between supercoiled DNA and partitioning protein ParB.
Read full: doi.org/10.1093/nar/...
Together with @gruberlab.bsky.social in Lausanne, we show the interaction between supercoiled DNA and partitioning protein ParB.
Read full: doi.org/10.1093/nar/...
November 27, 2024 at 10:07 PM
Out today in Nucleic Acids Research! My final publication from @ceesdekker.bsky.social lab together with A.M. Gonzalez !
Together with @gruberlab.bsky.social in Lausanne, we show the interaction between supercoiled DNA and partitioning protein ParB.
Read full: doi.org/10.1093/nar/...
Together with @gruberlab.bsky.social in Lausanne, we show the interaction between supercoiled DNA and partitioning protein ParB.
Read full: doi.org/10.1093/nar/...
Reposted by Miloš Tišma
Latest #CDlab paper in Nucleic Acid Research:
academic.oup.com/nar/article/...
Great work by Alejandro Martin-Gonzalez,
@tismaa.bsky.social ea collaboring with @gruberlab.bsky.social, showing the interplay of DNA supercoiling & ParB condensation, 2 processes that set bacterial genome organization.
academic.oup.com/nar/article/...
Great work by Alejandro Martin-Gonzalez,
@tismaa.bsky.social ea collaboring with @gruberlab.bsky.social, showing the interplay of DNA supercoiling & ParB condensation, 2 processes that set bacterial genome organization.
November 27, 2024 at 6:50 PM
Latest #CDlab paper in Nucleic Acid Research:
academic.oup.com/nar/article/...
Great work by Alejandro Martin-Gonzalez,
@tismaa.bsky.social ea collaboring with @gruberlab.bsky.social, showing the interplay of DNA supercoiling & ParB condensation, 2 processes that set bacterial genome organization.
academic.oup.com/nar/article/...
Great work by Alejandro Martin-Gonzalez,
@tismaa.bsky.social ea collaboring with @gruberlab.bsky.social, showing the interplay of DNA supercoiling & ParB condensation, 2 processes that set bacterial genome organization.
AMR awareness week ends today, but still something to keep in mind always!
www.who.int/campaigns/wo...
www.who.int/campaigns/wo...
World Antimicrobial Awareness Week 2024
World Antimicrobial Awareness Week aims to increase awareness of global antimicrobial resistance (AMR) and to encourage best practices.
www.who.int
November 24, 2024 at 4:49 PM
AMR awareness week ends today, but still something to keep in mind always!
www.who.int/campaigns/wo...
www.who.int/campaigns/wo...
Reposted by Miloš Tišma
Sign of the times, no more bluebird on the biorxiv engagement tab..
November 24, 2024 at 9:59 AM
Sign of the times, no more bluebird on the biorxiv engagement tab..
The migration of scientists and researchers en masse to this platform is great!
Time to pick up my time here a bit🤩
Time to pick up my time here a bit🤩
November 24, 2024 at 4:36 PM
The migration of scientists and researchers en masse to this platform is great!
Time to pick up my time here a bit🤩
Time to pick up my time here a bit🤩