Thomas Andrillon
@thomasandrillon.bsky.social
Studying the stream of consciousness during sleep and wakefulness
Neuroscientist at the Paris Brain Institute
Chargé de Recherche Inserm
Adjunct Senior Research Fellow at Monash University
Co-Editor-in-Chief of Neuroscience of Consciousness (OUP)
Neuroscientist at the Paris Brain Institute
Chargé de Recherche Inserm
Adjunct Senior Research Fellow at Monash University
Co-Editor-in-Chief of Neuroscience of Consciousness (OUP)
Check out this new model from @ivanmindlin.bsky.social, @rherzoga.bsky.social and friends showing that a local homeostatic inhibition allows for a broader repertoire of states, including spatial mosaics of wake and sleep-like activity.
Could this be the basis of the phenomenon of local sleep?
🧠🧪💤
Could this be the basis of the phenomenon of local sleep?
🧠🧪💤
📄Very happy to share our new pre-print!! 🧠
We introduce a homeostatic inhibitory plasticity rule into the Dynamic Mean Field (DMF) model which stabilizes firing rates and expands the model’s dynamical repertoire—for example, enabling slow-wave activity.
www.biorxiv.org/content/10.6...
⬇️⬇️⬇️
1/5
We introduce a homeostatic inhibitory plasticity rule into the Dynamic Mean Field (DMF) model which stabilizes firing rates and expands the model’s dynamical repertoire—for example, enabling slow-wave activity.
www.biorxiv.org/content/10.6...
⬇️⬇️⬇️
1/5
The impact of homeostatic inhibitory plasticity in a generative biophysical model
A main characteristic of biological systems is their capacity to dynamically adapt to environmental changes. In the brain, synaptic plasticity enables the strengthening or weakening of connections bet...
www.biorxiv.org
January 14, 2026 at 8:12 PM
Check out this new model from @ivanmindlin.bsky.social, @rherzoga.bsky.social and friends showing that a local homeostatic inhibition allows for a broader repertoire of states, including spatial mosaics of wake and sleep-like activity.
Could this be the basis of the phenomenon of local sleep?
🧠🧪💤
Could this be the basis of the phenomenon of local sleep?
🧠🧪💤
Reposted by Thomas Andrillon
📄Very happy to share our new pre-print!! 🧠
We introduce a homeostatic inhibitory plasticity rule into the Dynamic Mean Field (DMF) model which stabilizes firing rates and expands the model’s dynamical repertoire—for example, enabling slow-wave activity.
www.biorxiv.org/content/10.6...
⬇️⬇️⬇️
1/5
We introduce a homeostatic inhibitory plasticity rule into the Dynamic Mean Field (DMF) model which stabilizes firing rates and expands the model’s dynamical repertoire—for example, enabling slow-wave activity.
www.biorxiv.org/content/10.6...
⬇️⬇️⬇️
1/5
The impact of homeostatic inhibitory plasticity in a generative biophysical model
A main characteristic of biological systems is their capacity to dynamically adapt to environmental changes. In the brain, synaptic plasticity enables the strengthening or weakening of connections bet...
www.biorxiv.org
January 14, 2026 at 7:03 PM
📄Very happy to share our new pre-print!! 🧠
We introduce a homeostatic inhibitory plasticity rule into the Dynamic Mean Field (DMF) model which stabilizes firing rates and expands the model’s dynamical repertoire—for example, enabling slow-wave activity.
www.biorxiv.org/content/10.6...
⬇️⬇️⬇️
1/5
We introduce a homeostatic inhibitory plasticity rule into the Dynamic Mean Field (DMF) model which stabilizes firing rates and expands the model’s dynamical repertoire—for example, enabling slow-wave activity.
www.biorxiv.org/content/10.6...
⬇️⬇️⬇️
1/5
Reposted by Thomas Andrillon
A new comparative study of seven lizard species, including chameleons and bearded dragons, finds an ancient sleep rhythm conserved over millennia.
By Lauren Schenkman
www.thetransmitter.org/sleep/snoozi...
By Lauren Schenkman
www.thetransmitter.org/sleep/snoozi...
December 29, 2025 at 6:34 PM
A new comparative study of seven lizard species, including chameleons and bearded dragons, finds an ancient sleep rhythm conserved over millennia.
By Lauren Schenkman
www.thetransmitter.org/sleep/snoozi...
By Lauren Schenkman
www.thetransmitter.org/sleep/snoozi...
After 35 days at sea, Alexia and her team are passing Cape Horn!
Looping the loop!!!
Looping the loop!!!
January 6, 2026 at 1:55 PM
After 35 days at sea, Alexia and her team are passing Cape Horn!
Looping the loop!!!
Looping the loop!!!
This is the first article I read after my wife gave birth. It goes without saying it resonated deeply with what she told me of her experience and what I witnessed.
A beautiful and important piece. Have a look!
A beautiful and important piece. Have a look!
🚨 New article in #NCONSC
Reimagining pain as an allostatic imperative: perspectives from contemplative traditions
academic.oup.com/nc/article/2...
#consciousness
🧠🧪
Reimagining pain as an allostatic imperative: perspectives from contemplative traditions
academic.oup.com/nc/article/2...
#consciousness
🧠🧪
Reimagining pain as an allostatic imperative: perspectives from contemplative traditions
Abstract. The motivational force of pain is undeniable. But what pain commands us to do, how we might satisfy this command, and if our experience of pain i
academic.oup.com
January 5, 2026 at 3:41 PM
This is the first article I read after my wife gave birth. It goes without saying it resonated deeply with what she told me of her experience and what I witnessed.
A beautiful and important piece. Have a look!
A beautiful and important piece. Have a look!
Reposted by Thomas Andrillon
🚨 New article in #NCONSC
Functional connectivity drifts during sleep as a marker of fluctuations in the level of consciousness
academic.oup.com/nc/article/2...
#consciousness
🧠🧪
Functional connectivity drifts during sleep as a marker of fluctuations in the level of consciousness
academic.oup.com/nc/article/2...
#consciousness
🧠🧪
Functional connectivity drifts during sleep as a marker of fluctuations in the level of consciousness
Abstract. During the wake–sleep cycle, consciousness waxes and wanes, and this is thought to be reflected in varying levels of integration between brain ar
academic.oup.com
January 5, 2026 at 3:38 PM
🚨 New article in #NCONSC
Functional connectivity drifts during sleep as a marker of fluctuations in the level of consciousness
academic.oup.com/nc/article/2...
#consciousness
🧠🧪
Functional connectivity drifts during sleep as a marker of fluctuations in the level of consciousness
academic.oup.com/nc/article/2...
#consciousness
🧠🧪
Ever had someone ask "What are you thinking about?" and your honest answer was "Actually, nothing"?
In this essay for @psyche.co, I explain why "mind blanking" is more than just a glitch: it’s a window into how our brains toggle between being awake and asleep.
🧠🧪💤
psyche.co/ideas/what-y...
In this essay for @psyche.co, I explain why "mind blanking" is more than just a glitch: it’s a window into how our brains toggle between being awake and asleep.
🧠🧪💤
psyche.co/ideas/what-y...
What your mind’s blank moments reveal about consciousness | Psyche Ideas
Scientists are uncovering the nature of an elusive mental experience that challenges what it means to be conscious
psyche.co
January 5, 2026 at 1:17 PM
Ever had someone ask "What are you thinking about?" and your honest answer was "Actually, nothing"?
In this essay for @psyche.co, I explain why "mind blanking" is more than just a glitch: it’s a window into how our brains toggle between being awake and asleep.
🧠🧪💤
psyche.co/ideas/what-y...
In this essay for @psyche.co, I explain why "mind blanking" is more than just a glitch: it’s a window into how our brains toggle between being awake and asleep.
🧠🧪💤
psyche.co/ideas/what-y...
Infra-slow brain rhythms found in sleep in lizards, humans, rats and pigeons!
www.nature.com/articles/s41...
Congrats @antbergel.bsky.social!
www.nature.com/articles/s41...
Congrats @antbergel.bsky.social!
Sleep-dependent infraslow rhythms are evolutionarily conserved across reptiles and mammals - Nature Neuroscience
Bergel et al. show that an infraslow rhythm connecting the brain and body during sleep is shared by lizards, mammals and birds, revealing an ancestral process and reshaping our understanding of the ev...
www.nature.com
December 30, 2025 at 7:44 AM
Infra-slow brain rhythms found in sleep in lizards, humans, rats and pigeons!
www.nature.com/articles/s41...
Congrats @antbergel.bsky.social!
www.nature.com/articles/s41...
Congrats @antbergel.bsky.social!
What happens in your brain when you blank out?
Read a summary of our recent paper by @institutducerveau.bsky.social
parisbraininstitute.org/not-thinking...
Read a summary of our recent paper by @institutducerveau.bsky.social
parisbraininstitute.org/not-thinking...
December 29, 2025 at 9:45 PM
What happens in your brain when you blank out?
Read a summary of our recent paper by @institutducerveau.bsky.social
parisbraininstitute.org/not-thinking...
Read a summary of our recent paper by @institutducerveau.bsky.social
parisbraininstitute.org/not-thinking...
🚨 New paper in @pnas.org to end 2025 with a bang!🚨
Behavioral, experiential, and physiological signatures of mind blanking
www.pnas.org/doi/10.1073/...
with Esteban Munoz-Musat, @arthurlecoz.bsky.social @corcorana.bsky.social, Laouen Belloli and Lionel Naccache
Illustration: Ana Yael.
1/n
Behavioral, experiential, and physiological signatures of mind blanking
www.pnas.org/doi/10.1073/...
with Esteban Munoz-Musat, @arthurlecoz.bsky.social @corcorana.bsky.social, Laouen Belloli and Lionel Naccache
Illustration: Ana Yael.
1/n
December 29, 2025 at 10:11 AM
🚨 New paper in @pnas.org to end 2025 with a bang!🚨
Behavioral, experiential, and physiological signatures of mind blanking
www.pnas.org/doi/10.1073/...
with Esteban Munoz-Musat, @arthurlecoz.bsky.social @corcorana.bsky.social, Laouen Belloli and Lionel Naccache
Illustration: Ana Yael.
1/n
Behavioral, experiential, and physiological signatures of mind blanking
www.pnas.org/doi/10.1073/...
with Esteban Munoz-Musat, @arthurlecoz.bsky.social @corcorana.bsky.social, Laouen Belloli and Lionel Naccache
Illustration: Ana Yael.
1/n
Reposted by Thomas Andrillon
Our recent research on mind wandering is featured in Cerveau et Psycho, a French magazine on brain and cognition. Thanks, Thomas ;)
Article (FR): stm.cairn.info/magazine-cer...
#MindWandering #Neuroscience
@thomasandrillon.bsky.social
Article (FR): stm.cairn.info/magazine-cer...
#MindWandering #Neuroscience
@thomasandrillon.bsky.social
stm.cairn.info
December 20, 2025 at 12:51 PM
Our recent research on mind wandering is featured in Cerveau et Psycho, a French magazine on brain and cognition. Thanks, Thomas ;)
Article (FR): stm.cairn.info/magazine-cer...
#MindWandering #Neuroscience
@thomasandrillon.bsky.social
Article (FR): stm.cairn.info/magazine-cer...
#MindWandering #Neuroscience
@thomasandrillon.bsky.social
That's just amazing!
Very neat analysis of the current debate and a strong proposal to overcome the apparent aporia. Well done!
Very neat analysis of the current debate and a strong proposal to overcome the apparent aporia. Well done!
🎊📜 NEW PAPER 📜🎊
Can we seriously build synthetic consciousness?
And if so, where do we start?
I’m super excited to present recent publication in Neuroscience & Biobehavioral Reviews where @jaanaru.bsky.social and I confront this challenge head on.
1/n
Can we seriously build synthetic consciousness?
And if so, where do we start?
I’m super excited to present recent publication in Neuroscience & Biobehavioral Reviews where @jaanaru.bsky.social and I confront this challenge head on.
1/n
On biological and artificial consciousness: A case for biological computationalism
The rapid advances in the capabilities of Large Language Models (LLMs) have galvanised public and scientific debates over whether artificial systems m…
sciencedirect.com
December 18, 2025 at 10:40 PM
That's just amazing!
Very neat analysis of the current debate and a strong proposal to overcome the apparent aporia. Well done!
Very neat analysis of the current debate and a strong proposal to overcome the apparent aporia. Well done!
Reposted by Thomas Andrillon
🎊📜 NEW PAPER 📜🎊
Can we seriously build synthetic consciousness?
And if so, where do we start?
I’m super excited to present recent publication in Neuroscience & Biobehavioral Reviews where @jaanaru.bsky.social and I confront this challenge head on.
1/n
Can we seriously build synthetic consciousness?
And if so, where do we start?
I’m super excited to present recent publication in Neuroscience & Biobehavioral Reviews where @jaanaru.bsky.social and I confront this challenge head on.
1/n
On biological and artificial consciousness: A case for biological computationalism
The rapid advances in the capabilities of Large Language Models (LLMs) have galvanised public and scientific debates over whether artificial systems m…
sciencedirect.com
December 18, 2025 at 5:26 PM
🎊📜 NEW PAPER 📜🎊
Can we seriously build synthetic consciousness?
And if so, where do we start?
I’m super excited to present recent publication in Neuroscience & Biobehavioral Reviews where @jaanaru.bsky.social and I confront this challenge head on.
1/n
Can we seriously build synthetic consciousness?
And if so, where do we start?
I’m super excited to present recent publication in Neuroscience & Biobehavioral Reviews where @jaanaru.bsky.social and I confront this challenge head on.
1/n
Reposted by Thomas Andrillon
A hippocampal ‘sharp-wave sleep’ state that is dissociable from cortical sleep
www.nature.com/articles/s41...
www.nature.com/articles/s41...
A hippocampal ‘sharp-wave sleep’ state that is dissociable from cortical sleep - Nature Neuroscience
Through continuous multiday recordings in rats, the authors reveal that hippocampal sharp waves reflect sleep need and define a homeostatically regulated sleep state that enables the hippocampus to di...
www.nature.com
December 14, 2025 at 9:07 PM
A hippocampal ‘sharp-wave sleep’ state that is dissociable from cortical sleep
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Thomas Andrillon
If you analyse time-resolved data (M/EEG, iEEG, pupillometry, force recordings…) and feel limited by cluster-based permutation tests (CBPTs); especially when trying to determine when an effect starts or ends; you may want to try our new R package: lnalborczyk.github.io/neurogam/
#rstats #brms #EEG
#rstats #brms #EEG
Modelling time-resolved electrophysiological data with Bayesian generalised additive multilevel models
Providing utility functions for fitting Bayesian generalised additive multilevel models (BGAMMs) to time-resolved data (e.g., M/EEG, pupillometry, mouse-tracking, etc) and identifying clusters.
lnalborczyk.github.io
December 11, 2025 at 11:38 AM
If you analyse time-resolved data (M/EEG, iEEG, pupillometry, force recordings…) and feel limited by cluster-based permutation tests (CBPTs); especially when trying to determine when an effect starts or ends; you may want to try our new R package: lnalborczyk.github.io/neurogam/
#rstats #brms #EEG
#rstats #brms #EEG
"Research will be shared exclusively outside traditional journals"
This is quite a statement!
This is quite a statement!
This is HUGE! (Read it!!). I'll be cheering Doris and Astera Neuro on the entire way. Doris is a genius, both in the scope of her vision and in making things happen (that combination is rare). SO EXCITING! I can't wait to see what Astera Neuro discovers.
astera.org/neuroscienti...
astera.org/neuroscienti...
Neuroscientist Doris Tsao joins Astera to lead its new neuroscience program - Astera
The Astera Institute is excited to launch a major new neuroscience research effort led by Dr. Doris Tsao, who will be joining as Chief Scientist for Astera Neuro. We seek to understand one of the deep...
astera.org
December 10, 2025 at 8:32 PM
"Research will be shared exclusively outside traditional journals"
This is quite a statement!
This is quite a statement!
Not even a week after departure, they are already at the equator!
What a team!
What a team!
December 5, 2025 at 8:45 PM
Not even a week after departure, they are already at the equator!
What a team!
What a team!
Reposted by Thomas Andrillon
Very excited to share the first preprint of my PhD thesis!
Together with @tschreiner.bsky.social, we investigated how respiration coordinates signature neural expressions of successful remembering during memory retrieval. 🫁🧠
🧵(1/8)
Together with @tschreiner.bsky.social, we investigated how respiration coordinates signature neural expressions of successful remembering during memory retrieval. 🫁🧠
🧵(1/8)
Respiration shapes the neural dynamics of successful remembering in humans. https://www.biorxiv.org/content/10.1101/2025.04.17.649286v1
April 24, 2025 at 9:35 AM
Very excited to share the first preprint of my PhD thesis!
Together with @tschreiner.bsky.social, we investigated how respiration coordinates signature neural expressions of successful remembering during memory retrieval. 🫁🧠
🧵(1/8)
Together with @tschreiner.bsky.social, we investigated how respiration coordinates signature neural expressions of successful remembering during memory retrieval. 🫁🧠
🧵(1/8)
Reposted by Thomas Andrillon
😴🧠Next week for the QBio FRESK seminars, we will listen to Thomas Andrillon (ICM) about "Sleep : a window onto consciousness"
@thomasandrillon.bsky.social
@institutducerveau.bsky.social
qbio.ens.psl.eu/en/events/ex...
@thomasandrillon.bsky.social
@institutducerveau.bsky.social
qbio.ens.psl.eu/en/events/ex...
External seminar - Thomas Andrillon (ICM) | QBio
:
qbio.ens.psl.eu
December 4, 2025 at 10:51 AM
😴🧠Next week for the QBio FRESK seminars, we will listen to Thomas Andrillon (ICM) about "Sleep : a window onto consciousness"
@thomasandrillon.bsky.social
@institutducerveau.bsky.social
qbio.ens.psl.eu/en/events/ex...
@thomasandrillon.bsky.social
@institutducerveau.bsky.social
qbio.ens.psl.eu/en/events/ex...
Reposted by Thomas Andrillon
My very first paper is finally out in @pnas.org, with Catherine Tallon-Baudry and Patrick Haggard! Interoception, exteroception, the self and more, it's got it all.
Also it should go open access at some point
www.pnas.org/doi/10.1073/...
Also it should go open access at some point
www.pnas.org/doi/10.1073/...
Interoception vs. Exteroception: Cardiac interoception competes with tactile perception, yet also facilitates self-relevance encoding | PNAS
Internal bodily signals, notably the heartbeat, influence our perception of the external
world—but the nature of this influence remains unclear. Di...
www.pnas.org
December 3, 2025 at 9:35 AM
My very first paper is finally out in @pnas.org, with Catherine Tallon-Baudry and Patrick Haggard! Interoception, exteroception, the self and more, it's got it all.
Also it should go open access at some point
www.pnas.org/doi/10.1073/...
Also it should go open access at some point
www.pnas.org/doi/10.1073/...
Reposted by Thomas Andrillon
Good piece by @kohitij.bsky.social on why neuroscientists use an "outdated" vision model. Neuroscience is different than AI and that's ok! medium.com/@kohitij_716...
Why AlexNet Died in AI but Lingers in Neuroscience — Through the Lens of Popper and Kuhn
When I talk to any of my machine learning researcher colleagues in 2025, they tell me that a model from 2023 is prehistoric. In AI, a year…
medium.com
December 3, 2025 at 2:53 PM
Good piece by @kohitij.bsky.social on why neuroscientists use an "outdated" vision model. Neuroscience is different than AI and that's ok! medium.com/@kohitij_716...
🚨 New preprint on cortical slowing, stroke, and attention
**Sleep-like slow waves in wakefulness index post-stroke behavioural alterations**
Link:
www.biorxiv.org/content/10.1...
@dreamteamicm.bsky.social @institutducerveau.bsky.social
🧠🧪💤
**Sleep-like slow waves in wakefulness index post-stroke behavioural alterations**
Link:
www.biorxiv.org/content/10.1...
@dreamteamicm.bsky.social @institutducerveau.bsky.social
🧠🧪💤
Sleep-like slow waves in wakefulness index post-stroke behavioural alterations
Increases in high-amplitude, low-frequency EEG oscillations during non-rapid eye movement (NREM) sleep serve as markers of neuronal silencing, which disrupts functional connectivity and is associated ...
www.biorxiv.org
December 2, 2025 at 3:34 PM
🚨 New preprint on cortical slowing, stroke, and attention
**Sleep-like slow waves in wakefulness index post-stroke behavioural alterations**
Link:
www.biorxiv.org/content/10.1...
@dreamteamicm.bsky.social @institutducerveau.bsky.social
🧠🧪💤
**Sleep-like slow waves in wakefulness index post-stroke behavioural alterations**
Link:
www.biorxiv.org/content/10.1...
@dreamteamicm.bsky.social @institutducerveau.bsky.social
🧠🧪💤
“Leave the lab! Escape the ivory tower!” they said.
Hold our EEGs!
@dreamteamicm.bsky.social is teaming up with Alexia Barrier and The Famous Project, the first all-female crew racing the Trophée Jules Verne!
We’ll track their brain activity across 40 days at sea!
@institutducerveau.bsky.social
Hold our EEGs!
@dreamteamicm.bsky.social is teaming up with Alexia Barrier and The Famous Project, the first all-female crew racing the Trophée Jules Verne!
We’ll track their brain activity across 40 days at sea!
@institutducerveau.bsky.social
November 29, 2025 at 2:35 PM
“Leave the lab! Escape the ivory tower!” they said.
Hold our EEGs!
@dreamteamicm.bsky.social is teaming up with Alexia Barrier and The Famous Project, the first all-female crew racing the Trophée Jules Verne!
We’ll track their brain activity across 40 days at sea!
@institutducerveau.bsky.social
Hold our EEGs!
@dreamteamicm.bsky.social is teaming up with Alexia Barrier and The Famous Project, the first all-female crew racing the Trophée Jules Verne!
We’ll track their brain activity across 40 days at sea!
@institutducerveau.bsky.social
Reposted by Thomas Andrillon
Another cool study modelling shared somatosensory and visual representations during naturalistic video watching 👇
'Vicarious body maps bridge vision and touch in the human brain'
www.nature.com/articles/s41...
'Vicarious body maps bridge vision and touch in the human brain'
www.nature.com/articles/s41...
Vicarious body maps bridge vision and touch in the human brain - Nature
A mode of brain organization that connects visual and bodily reference frames may translate raw sensory impressions into more abstract formats that are useful for action, social cognition and semantic...
www.nature.com
November 27, 2025 at 10:25 PM
Another cool study modelling shared somatosensory and visual representations during naturalistic video watching 👇
'Vicarious body maps bridge vision and touch in the human brain'
www.nature.com/articles/s41...
'Vicarious body maps bridge vision and touch in the human brain'
www.nature.com/articles/s41...
Reposted by Thomas Andrillon
Sleep supports brain health partly by regulating fluid dynamics to clear waste. @ulvlarsen.bsky.social &co probe the relation between #sleep & fluid movement in the human #brain, finding that #SleepPressure & intensity have distinct effects on brain pulsations @plosbiology.org 🧪 plos.io/3XQWCL6
November 25, 2025 at 5:40 PM
Sleep supports brain health partly by regulating fluid dynamics to clear waste. @ulvlarsen.bsky.social &co probe the relation between #sleep & fluid movement in the human #brain, finding that #SleepPressure & intensity have distinct effects on brain pulsations @plosbiology.org 🧪 plos.io/3XQWCL6