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thekatybrown.bsky.social
Katy Brown
@thekatybrown.bsky.social
1.5K followers 2.9K following 70 posts
Postdoc in computational genomics studying RNA viruses at Cambridge. She/Her https://orcid.org/0000-0002-8400-6922
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thekatybrown.bsky.social
Proud to have been a part of this! www.cell.com/cell/fulltex...
November 17, 2025 at 10:41 AM
thekatybrown.bsky.social
My paper is out! Uncovering hundreds of exogenous and endogenous RNA viral RdRp sequences amongst uncharacterised sequences in public protein databases. doi.org/10.1093/ve/v... 💻🧬 1/5 🧵
October 28, 2025 at 1:27 PM
Reposted by Katy Brown
denzquix.bsky.social
I translated "Jeff Jet: Abenteuer InfoHighway" as "Jeff Jet: Adventure on the InfoHighway" archive.org/details/jeff... - a German promotional adventure game for Hewlett Packard from 1995.
Title screen for "Jeff Jet: Adventure on the InfoHighway". Screenshot from "Jeff Jet: Adventure on the InfoHighway". In front of a green room that seems to be built out of giant circuit board pieces, there are close-up pictures of Jeff Jet and an NPC wearing glasses and a red sweater. A line of dialog is visible between them: "Good day to you!". Screenshot from "Jeff Jet: Adventure on the InfoHighway". The two main characters, Jeff and Donna, are standing near a road tunnel with a closed barrier gate in front of it and a guard standing by. There is a large truck loaded with gigantic ones and zeroes. The mouse cursor is hovering over these ones and zeroes, and the word "Bits" appears next to it. Screenshot from "Jeff Jet: Adventure on the InfoHighway". One of the main characters, Donna, stands in the middle of a large desert tent with visible patches and holes. A small office area has been set up behind her, with a woman sitting at a desk with a computer on it. There is an empty chair with a green coat lying on it in the foreground facing the desk. At the bottom of the screen, there is a row of inventory items. The mouse cursor is over one of them, a red and green magnet, with the word "Magnet" shown next to it.
September 22, 2025 at 4:47 PM
thekatybrown.bsky.social
Come to the BOKR session at 2:20 and see Charlotte Tumescheit @schnamo.bsky.social give a super interesting talk about improving prediction of molecular properties by incorporating ontologies. #ISMBECCB2025
July 23, 2025 at 1:30 PM
thekatybrown.bsky.social
Someone needs to implement an LLM to help select which talks to go to at #ISMBECCB2025
July 23, 2025 at 1:22 PM
thekatybrown.bsky.social
Come and see me in the ice rink if you want to plot phylogenies in matplotlib! Poster 206. GitHub.com/KatyBrown/plot_phylo #ISMBECCB2025
July 22, 2025 at 9:13 AM
Reposted by Katy Brown
mmarchin.bsky.social
I reformatted the #ISMBECCB2025 schedule a bit - in case anyone else wants to use it this way - ordered by day and start time:

csv: drive.google.com/file/d/1JyhT...

xlsx:
docs.google.com/spreadsheets...
ISMBECCB_2025_All_Detailed_Schedule.csv
drive.google.com
July 21, 2025 at 8:05 AM
thekatybrown.bsky.social
Excited for the ISMB/ECCB conference! I have two posters A520 today about an endogenous and exogenous virus I found in nematodes - and B206 tomorrow about my tool plot_phylo for drawing phylogenies in matplotlib. #ISMBECCB2025
July 21, 2025 at 8:04 AM
thekatybrown.bsky.social
Is it so much to ask for all my bullet points to be 1. the same size and 2. in a straight line?
July 9, 2025 at 11:08 AM
thekatybrown.bsky.social
I could do my job in half the time if we just picked a column delimiter and stuck with it and then no-one can use that symbol for anything else. Let's not use * to both delimit columns and represent a stop codon, or use a random number of spaces, or put "_" in our sequence IDs. 🖥️🧪
June 27, 2025 at 1:57 PM
Reposted by Katy Brown
plosbiology.org
From student to researcher, a #career in #science can come with a high price tag. @drcraigmc.bsky.social explores how wealth shapes opportunity in #STEM and proposes structural changes to support #equity and inclusion. 🧪
plos.io/4edGlY4
Too poor to science: How wealth determines who succeeds in STEM
From student to researcher, a career in science can come with a high price tag. This Perspective explores how persistent financial barriers limit who can succeed in science, revealing how wealth shape...
plos.io
June 24, 2025 at 9:41 AM
Reposted by Katy Brown
thatdocphoenix.com
There should be a ban on broadcasters using footage of “anonymous” (heads cropped out) larger people - who could nevertheless recognise themselves based on knowing their own bodies and clothes - to illustrate stories about obesity, fat or weight loss
June 23, 2025 at 10:56 AM
thekatybrown.bsky.social
Are you interested in using AI to decode RNA? Have a look at this brilliant new review from my friend @schnamo.bsky.social and her colleagues.
June 23, 2025 at 9:16 AM
thekatybrown.bsky.social
Just a reminder to please fill out this form if you’d be interest in an EVE / ERV meeting 📋🥳
thekatybrown.bsky.social Katy Brown @thekatybrown.bsky.social · May 27
I'm thinking of organising a meeting on endogenous viral elements (RNA, DNA and retroviral) - if you'd potentially be interested, please fill out the form here - forms.gle/wrCiWMw4yXZe... - so I can gauge interest. Please RT or share with anyone maybe interested! 🧪🧬🖥️🦠 #virology #bioinformatics
EVE Meeting Expression of Interest
forms.gle
June 4, 2025 at 8:19 AM
Reposted by Katy Brown
cryptogenomicon.bsky.social
NIH funding supporting the HMMER and Infernal software projects has been terminated. NIH states that our work, as well as all other federally funded research at Harvard, is of no benefit to the US.
May 22, 2025 at 12:42 PM
thekatybrown.bsky.social
@ariskatzourakis.bsky.social @robjgifford.bsky.social @lequimelab.eu @emma-harding.bsky.social
thekatybrown.bsky.social Katy Brown @thekatybrown.bsky.social · May 27
I'm thinking of organising a meeting on endogenous viral elements (RNA, DNA and retroviral) - if you'd potentially be interested, please fill out the form here - forms.gle/wrCiWMw4yXZe... - so I can gauge interest. Please RT or share with anyone maybe interested! 🧪🧬🖥️🦠 #virology #bioinformatics
EVE Meeting Expression of Interest
forms.gle
May 28, 2025 at 11:05 AM
thekatybrown.bsky.social
I'm thinking of organising a meeting on endogenous viral elements (RNA, DNA and retroviral) - if you'd potentially be interested, please fill out the form here - forms.gle/wrCiWMw4yXZe... - so I can gauge interest. Please RT or share with anyone maybe interested! 🧪🧬🖥️🦠 #virology #bioinformatics
EVE Meeting Expression of Interest
forms.gle
May 27, 2025 at 11:53 AM
Reposted by Katy Brown
denzquix.bsky.social
"Action in Hollywood" is one of several promotional games released in the 1990s for Bi-Fi Rolls, a salami-based snack originating in Germany and sold across Europe.
May 16, 2025 at 6:24 PM
Reposted by Katy Brown
denzquix.bsky.social
I translated "Bi-Fi: Action in Hollywood" (1994) for MS-DOS, one of the more ambitious and fully-developed promotional games of the era. Huge thanks to @sonneveld.bsky.social for helping me with the technical aspects on this one. archive.org/details/bifi...
The title screen for "Bi-Fi Roll: Action in Hollywood" (1994). The main character, Lukas, stands with his arms folded below the Bi-Fi Roll logo and beside a clapperboard reading "Action in Hollywood". A film reel of scenes from the game runs down the side of the screen. A scene from "Bi-Fi: Action in Hollywood". On a sci-fi set, the main character Lukas is talking to a man whose bottom half is trapped in a small hatch. There is a conversation menu with three options: "What are you doing in there?" "Want me to heave you out of there?" "How can I help?" A scene from "Bi-Fi: Action in Hollywood". Lukas is on the set of a movie featuring dinosaurs. He stands in front of a T-Rex three times his height. The T-Rex is wearing red glasses. A sign by the doo is similar to the design of the Jurassic Park logo, and reads "Dino Zoo". A scene from "Bi-Fi: Action in Hollywood". Lukas is standing in the doorway of the studio cafeteria. A couple of people are seated on the tables. The mouse cursor is hovering over a Bi-Fi Roll in the player's inventory and the action line reads "Eat Bi-Fi Roll".
May 16, 2025 at 6:18 PM
thekatybrown.bsky.social
Excited for #RdRpSummit2025 and #ViBioM2025! Just starting off now in Lisbon.
May 11, 2025 at 9:23 AM
Reposted by Katy Brown
rdrpsummit.bsky.social
Here we go! The #RdRpSummit2025 is live!
@ingrida.bsky.social
May 11, 2025 at 9:11 AM
Reposted by Katy Brown
denzquix.bsky.social
v1.0 of "King's Quest 1: Rubber Tree Edition" is up! Apply the mod here: denzquix.github.io/agi-patch/ You will need the files from the non-enhanced DOS version. The patched files will run in ScummVM under the "Fan AGI" option, or in DOSBox if you include other files from the original game folder.
denzquix.bsky.social denzquix @denzquix.bsky.social · Nov 14
Current project: a mod for King's Quest 1 (AGI) which adds >UNDO and circumvents softlocks, titled King's Quest: Rubber Tree Edition. A pre-release version was recently featured on stream by the inimitable @emmxyzzy.bsky.social
An edited demo clip of the King's Quest 1 "Rubber Tree Edition" mod, showing Graham falling from a giant beanstalk while climbing it, but the player types "undo" while he plummets, which instantly places him safely back where he fell from. A screenshot of the intro screen for the Rubber Tree Edition mod for King's Quest 1. It reads: Let it be Known that this Rendition of "KING'S QUEST" is an Unsanctioned MODIFICATION, concocted by THE ORDER OF THE RUBBER TREE. Acolytes of this elusive Sect do Conspire from the Shadows, manipulating Events to avert so-called UNWINNABLE SITUATIONS; Furthermore, they claim the right to overrule DEATH ITSELF via the use of the arcane incantation "UNDO". Those who Abide by this Sacrilegious "NERFING" do so at the Risk to their very Souls. Rubber Tree Edition version 1.0 Beta 2.
April 29, 2025 at 5:14 PM
Reposted by Katy Brown
martinsteinegger.bsky.social
Visit our posters at #RECOMB2025 for:

Structural: MSAs, Virus DB, Core Genes, Motif Discovery, Multimer Clustering & Search, pLM Foldseek, Environmental analysis

Metagenomics: Classification & Metabuli App

GPU-based & RNA search, Proteome clustering, Novel Ribozyme discovery

& get Marv stickers!
April 25, 2025 at 7:46 AM
thekatybrown.bsky.social
I've never related to a plant more.
April 8, 2025 at 1:08 PM
Reposted by Katy Brown
jomiles.bsky.social
It's also the day for my favorite meme!

If this aging Klingon warrior can get it right, so can anyone.
Jadzia Dax and Kor hugging: "Curzon, my beloved old friend." "I'm Jadzia now." "Jadzia, my beloved old friend!"
March 31, 2025 at 3:12 PM