Thea Jacobs
@theajacobs.bsky.social
Postdoc in the Luschnig lab. Flyologist 🪰 here to share my excitement about actomyosin.
Check out how contractility controls paracellular permeability here: https://shorturl.at/Wnb2n
Check out how contractility controls paracellular permeability here: https://shorturl.at/Wnb2n
Reposted by Thea Jacobs
Job Alert! The Institute for Neuro- and Behavioural Biology at the Faculty of Biology @uni-muenster.de invites applications for a Full Professorship (W3) in “Systems Neuroscience” - Highly attractive research environment at the Multiscale Imaging Center. Apply by January 5th. See shorturl.at/VczFp
November 12, 2025 at 5:42 PM
Job Alert! The Institute for Neuro- and Behavioural Biology at the Faculty of Biology @uni-muenster.de invites applications for a Full Professorship (W3) in “Systems Neuroscience” - Highly attractive research environment at the Multiscale Imaging Center. Apply by January 5th. See shorturl.at/VczFp
Reposted by Thea Jacobs
Excited to embark on this scientific journey with Ewa Paluch and Daniel StJohnston to understand fundamentals of epithelial tissue and cell shapes! Thank you to @erc.europa.eu for the support!
🚀 Exciting news! ERC Synergy Grant of €8.5 million to Sara Wickström @sarawickstrom.bsky.social, Daniel St Jonston @gurdoninstitute.bsky.social and Ewa Paluch @universitypress.cambridge.org! This highly interdisciplinary project will boost our understanding of tissue biology. #ERCSyG @erc.europa.eu
November 6, 2025 at 12:14 PM
Excited to embark on this scientific journey with Ewa Paluch and Daniel StJohnston to understand fundamentals of epithelial tissue and cell shapes! Thank you to @erc.europa.eu for the support!
Reposted by Thea Jacobs
Mark your calendars! The next SFB 1348 International Meeting will take place in #Münster from May 27-29, 2026, with a focus on #Mechanochemical signals at cellular interfaces. Stay tuned for more details and updates at www.uni-muenster.de/SFB1348/en/m...
October 27, 2025 at 7:00 AM
Mark your calendars! The next SFB 1348 International Meeting will take place in #Münster from May 27-29, 2026, with a focus on #Mechanochemical signals at cellular interfaces. Stay tuned for more details and updates at www.uni-muenster.de/SFB1348/en/m...
Reposted by Thea Jacobs
Approximately 14,000 visitors attended the “Lange Nacht der Universitätsmedizin Münster”, which marked the highlight of the anniversary year celebrating 100 years of the Faculty of Medicine and the University Hospital. www.uni-muenster.de/Cells-in-Mot...
@sfb1348.bsky.social @uni-muenster.de
@sfb1348.bsky.social @uni-muenster.de
Photo gallery: “Lange Nacht der Universitätsmedizin” – Impressions from the Multiscale Imaging Centre
On September 12, 2025, the University and University Hospital Münster opened their doors to the public during the “Lange Nacht der Universitätsmedizin”. At the Multiscale Imaging Centre, many visitors...
www.uni-muenster.de
September 16, 2025 at 6:55 AM
Approximately 14,000 visitors attended the “Lange Nacht der Universitätsmedizin Münster”, which marked the highlight of the anniversary year celebrating 100 years of the Faculty of Medicine and the University Hospital. www.uni-muenster.de/Cells-in-Mot...
@sfb1348.bsky.social @uni-muenster.de
@sfb1348.bsky.social @uni-muenster.de
Reposted by Thea Jacobs
Besuchen Sie uns zur „Langen Nacht der Unimedizin Münster“ am 12. September 2025! Zahlreiche Forschungsgruppen aus der Zell-Dynamik- und Imaging-Community der @uni-muenster.de und @sfb1348.bsky.social öffnen ihre Labore für die Öffentlichkeit!
lange-nacht-muenster.de
lange-nacht-muenster.de
Lange Nacht der Universitätsmedizin Münster - Lange Nacht - 100 Jahre Universitätsmedizin Münster
Über 12.000 Menschen aus 100 Ländern, 150 Berufe, mehr als 30 Ausbildungsgänge – willkommen in der lebendigen Welt der Universitätsmedizin. Willkommen zur Entdecken Sie die Universitätsmedizin Münster...
lange-nacht-muenster.de
September 9, 2025 at 2:07 PM
Besuchen Sie uns zur „Langen Nacht der Unimedizin Münster“ am 12. September 2025! Zahlreiche Forschungsgruppen aus der Zell-Dynamik- und Imaging-Community der @uni-muenster.de und @sfb1348.bsky.social öffnen ihre Labore für die Öffentlichkeit!
lange-nacht-muenster.de
lange-nacht-muenster.de
Super cool work from our institute!
Epithelial tissues cover the inner and outer surfaces of the body. A study by the working group of cell biologist Prof Carsten Grashoff now provides insight into the molecular details underlying the formation of the connections between epithelial cells. #Biology
How epithelial junctions mature: Study shows conformational transition in key protein
Epithelial tissues cover the inner and outer surfaces of the body. A study by the working group of cell biologist Prof. Carsten Grashoff now provides insight into the molecular details underlying the ...
www.uni-muenster.de
September 10, 2025 at 8:10 AM
Super cool work from our institute!
Reposted by Thea Jacobs
Supracellular control and coordination of tissue morphogenesis, through supracellular actomyosin assemblies, that is what my lab @cellbiol-mrclmb.bsky.social @pdncambridge.bsky.social and I like to dig into at the moment! Fascinating and beautiful! journals.biologists.com/dev/article/...
August 27, 2025 at 12:33 PM
Supracellular control and coordination of tissue morphogenesis, through supracellular actomyosin assemblies, that is what my lab @cellbiol-mrclmb.bsky.social @pdncambridge.bsky.social and I like to dig into at the moment! Fascinating and beautiful! journals.biologists.com/dev/article/...
Reposted by Thea Jacobs
pYtags - our in vivo biosensors for receptor tyrosine kinases - in all their beauty on the cover of Cell Reports! Read more here: www.cell.com/cell-reports...
July 22, 2025 at 8:52 PM
pYtags - our in vivo biosensors for receptor tyrosine kinases - in all their beauty on the cover of Cell Reports! Read more here: www.cell.com/cell-reports...
Reposted by Thea Jacobs
🥁 New article 📢: #Mechanobiology of #development during #Drosophila #gastrulation using #Brillouin microscopy, now in @natcomms.nature.com : rdcu.be/ev6ZX
Collab. w/ @Prevedel_Lab @embl.org , Maria Leptin @marialep.bsky.social, @abhisha-thayambath.bsky.social, Julio Belmonte @ncstate.bsky.social
Collab. w/ @Prevedel_Lab @embl.org , Maria Leptin @marialep.bsky.social, @abhisha-thayambath.bsky.social, Julio Belmonte @ncstate.bsky.social
July 15, 2025 at 2:12 PM
🥁 New article 📢: #Mechanobiology of #development during #Drosophila #gastrulation using #Brillouin microscopy, now in @natcomms.nature.com : rdcu.be/ev6ZX
Collab. w/ @Prevedel_Lab @embl.org , Maria Leptin @marialep.bsky.social, @abhisha-thayambath.bsky.social, Julio Belmonte @ncstate.bsky.social
Collab. w/ @Prevedel_Lab @embl.org , Maria Leptin @marialep.bsky.social, @abhisha-thayambath.bsky.social, Julio Belmonte @ncstate.bsky.social
Reposted by Thea Jacobs
Using a simple model – #FruitFly eggs – biologist @theajacobs.bsky.social is investigating how cells build connections, and thus form tissues that only allow certain substances or cells to pass through. Here, she provides insight into her day-to-day research. @sfb1348.bsky.social
uni.ms/d3ry0
uni.ms/d3ry0
How does the yolk get into the egg? Studies on the fruit fly | Thea Jacobs
Cells build connections in organisms, and thus, form tissues that only allow certain substances or cells to pass through. In her doctoral thesis, biologist Thea Jacobs has carried out investigations o...
uni.ms
July 11, 2025 at 10:45 AM
Using a simple model – #FruitFly eggs – biologist @theajacobs.bsky.social is investigating how cells build connections, and thus form tissues that only allow certain substances or cells to pass through. Here, she provides insight into her day-to-day research. @sfb1348.bsky.social
uni.ms/d3ry0
uni.ms/d3ry0
Reposted by Thea Jacobs
Neurobiologist Bente Winkler @b-wink.bsky.social investigates how the brain reacts to #neuroinflammation. For this, she is using genetically modified #Drosophila flies that enable an artificial activation of the immune system. Read more: uni.ms/48q7k
Inflammation in the brain: My research on the fruit fly | Bente Winkler
Neurobiologist Dr Bente Winkler is investigating how fruit fly brains react to inflammation. To do this, she is using genetically modified fruit flies in which a reaction of the immune system can be a...
uni.ms
July 11, 2025 at 8:38 AM
Neurobiologist Bente Winkler @b-wink.bsky.social investigates how the brain reacts to #neuroinflammation. For this, she is using genetically modified #Drosophila flies that enable an artificial activation of the immune system. Read more: uni.ms/48q7k
Reposted by Thea Jacobs
Exciting @sfb1348.bsky.social with Katja Rust (Philipps-University Marburg) on Thursday. She will speak about "A single-cell analysis of Hh and EGFR-RAS: Independent signaling pathways prevent tumorigenesis". More information: www.uni-muenster.de/SFB1348/en/i...
Everyone is welcome!
Everyone is welcome!
July 7, 2025 at 9:38 AM
Exciting @sfb1348.bsky.social with Katja Rust (Philipps-University Marburg) on Thursday. She will speak about "A single-cell analysis of Hh and EGFR-RAS: Independent signaling pathways prevent tumorigenesis". More information: www.uni-muenster.de/SFB1348/en/i...
Everyone is welcome!
Everyone is welcome!
It’s #FluorescenceFriday again!
@maikbischoff.bsky.social encouraged me to post more beautiful images, so I hope you enjoy this image of Ajuba at Tricellular Junctions in #Drosophila 🪰 want to know more? Click here: doi.org/10.1016/j.cu...
@maikbischoff.bsky.social encouraged me to post more beautiful images, so I hope you enjoy this image of Ajuba at Tricellular Junctions in #Drosophila 🪰 want to know more? Click here: doi.org/10.1016/j.cu...
July 4, 2025 at 12:08 PM
It’s #FluorescenceFriday again!
@maikbischoff.bsky.social encouraged me to post more beautiful images, so I hope you enjoy this image of Ajuba at Tricellular Junctions in #Drosophila 🪰 want to know more? Click here: doi.org/10.1016/j.cu...
@maikbischoff.bsky.social encouraged me to post more beautiful images, so I hope you enjoy this image of Ajuba at Tricellular Junctions in #Drosophila 🪰 want to know more? Click here: doi.org/10.1016/j.cu...
Reposted by Thea Jacobs
🥰 Self-supervised, label-free 3D cell imaging is here
Congrats to Cyril on this very cool first, first author publication 🏆! This started when he was a bachelor's student (and he's now completing his masters!).
And many thanks to my other awesome co-authors🙏
elifesciences.org/articles/99848
Congrats to Cyril on this very cool first, first author publication 🏆! This started when he was a bachelor's student (and he's now completing his masters!).
And many thanks to my other awesome co-authors🙏
elifesciences.org/articles/99848
Self-supervised, label-free 3D cell imaging is here
EPFL researchers introduce CellSeg3D, a self-supervised tool for 3D cell segmentation in fluorescence microscopy, eliminating the need for manual labeling and enhancing accessibility for various biolo...
actu.epfl.ch
June 24, 2025 at 5:53 PM
🥰 Self-supervised, label-free 3D cell imaging is here
Congrats to Cyril on this very cool first, first author publication 🏆! This started when he was a bachelor's student (and he's now completing his masters!).
And many thanks to my other awesome co-authors🙏
elifesciences.org/articles/99848
Congrats to Cyril on this very cool first, first author publication 🏆! This started when he was a bachelor's student (and he's now completing his masters!).
And many thanks to my other awesome co-authors🙏
elifesciences.org/articles/99848
Reposted by Thea Jacobs
Just one week to go ⏳ until the "Cellular Interfaces Across Scales: From Molecules to Tissue Dynamics" meeting @sfb1348.bsky.social @uni-muenster.de
We can't wait to see you there!
crc1348-conference.ycode.site
#DynamicCellularInterfaces #Münster
We can't wait to see you there!
crc1348-conference.ycode.site
#DynamicCellularInterfaces #Münster
April 29, 2025 at 3:25 PM
Just one week to go ⏳ until the "Cellular Interfaces Across Scales: From Molecules to Tissue Dynamics" meeting @sfb1348.bsky.social @uni-muenster.de
We can't wait to see you there!
crc1348-conference.ycode.site
#DynamicCellularInterfaces #Münster
We can't wait to see you there!
crc1348-conference.ycode.site
#DynamicCellularInterfaces #Münster
Reposted by Thea Jacobs
Great Dispatch article by @tarafinegan.bsky.social on our new paper by @theajacobs.bsky.social in @currentbiology.bsky.social - thanks for condensing our findings so clearly and nicely!
Epithelial biology: Holding the corners together: shorturl.at/cMziC
@sfb1348.bsky.social @uni-muenster.de
Epithelial biology: Holding the corners together: shorturl.at/cMziC
@sfb1348.bsky.social @uni-muenster.de
Epithelial biology: Holding the corners together
A new study reveals that the Drosophila follicular epithelium opens its permeability
barrier to allow passage of yolk to the oocyte by relaxing, not actively pulling open,
cell vertices. This work res...
www.cell.com
March 24, 2025 at 3:15 PM
Great Dispatch article by @tarafinegan.bsky.social on our new paper by @theajacobs.bsky.social in @currentbiology.bsky.social - thanks for condensing our findings so clearly and nicely!
Epithelial biology: Holding the corners together: shorturl.at/cMziC
@sfb1348.bsky.social @uni-muenster.de
Epithelial biology: Holding the corners together: shorturl.at/cMziC
@sfb1348.bsky.social @uni-muenster.de
Reposted by Thea Jacobs
This dot is a region that intersect multiple cell junctions in an epithelia. These dots act as tiny anchors of cell contacts and they’re critical for epithelial coherence during homeostasis AND development.
I’m @katecavanaugh.bsky.social and I’ll be your guide on this 🧵 about tricellular vertices.
I’m @katecavanaugh.bsky.social and I’ll be your guide on this 🧵 about tricellular vertices.
March 9, 2025 at 6:45 AM
This dot is a region that intersect multiple cell junctions in an epithelia. These dots act as tiny anchors of cell contacts and they’re critical for epithelial coherence during homeostasis AND development.
I’m @katecavanaugh.bsky.social and I’ll be your guide on this 🧵 about tricellular vertices.
I’m @katecavanaugh.bsky.social and I’ll be your guide on this 🧵 about tricellular vertices.
Reposted by Thea Jacobs
Paris Now #StandUpForScience
@standupforscience.bsky.social
@standupforscifr.bsky.social
compliments of sulekh.bsky.social one of our postdocs!
@standupforscience.bsky.social
@standupforscifr.bsky.social
compliments of sulekh.bsky.social one of our postdocs!
March 7, 2025 at 2:36 PM
Paris Now #StandUpForScience
@standupforscience.bsky.social
@standupforscifr.bsky.social
compliments of sulekh.bsky.social one of our postdocs!
@standupforscience.bsky.social
@standupforscifr.bsky.social
compliments of sulekh.bsky.social one of our postdocs!
Reposted by Thea Jacobs
Some happy news. Pleased to see our paper showing how afadin strengthens cytoskeletal engagement by the cadherin-catenin cell adhesion complex out in Science Advances: bit.ly/3EFpD6h
Afadin mediates cadherin-catenin complex clustering on F-actin linked to cooperative binding and filament curvature
Afadin strengthens adherens junctions by stabilizing cadherin-catenin complex clusters on curved F-actin.
bit.ly
February 18, 2025 at 3:37 AM
Some happy news. Pleased to see our paper showing how afadin strengthens cytoskeletal engagement by the cadherin-catenin cell adhesion complex out in Science Advances: bit.ly/3EFpD6h
Reposted by Thea Jacobs
#science - in the light of potential enshittification of #PubMed - Ihere's an European alternative to PubMed - www.europepmc.org
It's not censored or brought down by would-be-dictators.🧪
It's not censored or brought down by would-be-dictators.🧪
March 2, 2025 at 11:59 AM
#science - in the light of potential enshittification of #PubMed - Ihere's an European alternative to PubMed - www.europepmc.org
It's not censored or brought down by would-be-dictators.🧪
It's not censored or brought down by would-be-dictators.🧪
Reposted by Thea Jacobs
Our new paper by @theajacobs.bsky.social in @currentbiology.bsky.social shows how relaxation of tension, rather than active actomyosin-based force, allows opening of cell #vertices to increase #epithelial permeability shorturl.at/Wnb2n
@sfb1348.bsky.social @uni-muenster.de
@sfb1348.bsky.social @uni-muenster.de
Rho/Rok-dependent regulation of actomyosin contractility at tricellular junctions restricts epithelial permeability in Drosophila
Cell vertices integrate forces in epithelia and play key roles in regulating barrier
function. Jacobs et al. show that modulation of actomyosin contractility at cell vertices
controls tricellular junc...
www.cell.com
February 17, 2025 at 4:01 PM
Our new paper by @theajacobs.bsky.social in @currentbiology.bsky.social shows how relaxation of tension, rather than active actomyosin-based force, allows opening of cell #vertices to increase #epithelial permeability shorturl.at/Wnb2n
@sfb1348.bsky.social @uni-muenster.de
@sfb1348.bsky.social @uni-muenster.de
Reposted by Thea Jacobs
It's always mesmerizing seeing how these group of cells move.
ℹ️Border cells invading through nurse cells
ℹ️Drosophila S9 egg chambers
ℹ️Border cells invading through nurse cells
ℹ️Drosophila S9 egg chambers
January 21, 2025 at 10:56 AM
It's always mesmerizing seeing how these group of cells move.
ℹ️Border cells invading through nurse cells
ℹ️Drosophila S9 egg chambers
ℹ️Border cells invading through nurse cells
ℹ️Drosophila S9 egg chambers
#fluorescentfriday with a Drosophila ovariole stained for E-Cad (cyan) and F-Actin (magenta). We use the follicle epithelium as a model to study junction remodelling and barrier formation. Check out our preprint on how Rok regulates paracellular permeability: www.biorxiv.org/content/10.1...
November 22, 2024 at 9:14 AM
#fluorescentfriday with a Drosophila ovariole stained for E-Cad (cyan) and F-Actin (magenta). We use the follicle epithelium as a model to study junction remodelling and barrier formation. Check out our preprint on how Rok regulates paracellular permeability: www.biorxiv.org/content/10.1...
Reposted by Thea Jacobs
5/ 🐣 With this technology at hand, we build the Virtual Embryo Zoo (virtual-embryo-zoo.sf.czbiohub.org), a showcase of cell-tracking datasets from 6 model organisms, including zebrafish and Drosophila. Explore them interactively, trace lineages, and download tracking data for further analysis! 🐠🐭
November 13, 2024 at 7:53 PM
5/ 🐣 With this technology at hand, we build the Virtual Embryo Zoo (virtual-embryo-zoo.sf.czbiohub.org), a showcase of cell-tracking datasets from 6 model organisms, including zebrafish and Drosophila. Explore them interactively, trace lineages, and download tracking data for further analysis! 🐠🐭