Andrew Steele
@statto.bsky.social
Ageing biologist (aren’t we all?)
Author of https://ageless.link/
Presenter of https://www.youtube.com/DrAndrewSteele
Founder of @thelongevityinitiative.org
Author of https://ageless.link/
Presenter of https://www.youtube.com/DrAndrewSteele
Founder of @thelongevityinitiative.org
Pinned
Andrew Steele
@statto.bsky.social
· Oct 23
Hi! I’m a longevity scientist, writer and campaigner. #introduction
My book, Ageless, is out in paperback! ‘A tour de force of anti-ageing science’ – The Times ageless.link
Or, check out my YouTube channel! This is a video on the most promising longevity drugs: youtu.be/RODwPAdtrw8
My book, Ageless, is out in paperback! ‘A tour de force of anti-ageing science’ – The Times ageless.link
Or, check out my YouTube channel! This is a video on the most promising longevity drugs: youtu.be/RODwPAdtrw8
Reposted by Andrew Steele
And Peter Attia MD telling Epstein the biggest problem with being his friend is he can’t tell anyone about the life he lives. Nice.
January 31, 2026 at 7:11 AM
And Peter Attia MD telling Epstein the biggest problem with being his friend is he can’t tell anyone about the life he lives. Nice.
Reposted by Andrew Steele
Here is Peter Attia MD emailing Epstein’s assistant claiming he goes into “JE withdrawal” when he doesn’t see him.
January 31, 2026 at 6:50 AM
Here is Peter Attia MD emailing Epstein’s assistant claiming he goes into “JE withdrawal” when he doesn’t see him.
Reposted by Andrew Steele
Oh look, according to Peter Attia MD “pussy is low carb” something that is totally normal for a doctor to say to Epstein, who had previously been convicted of procuring a child for prostitution
January 31, 2026 at 4:04 PM
Oh look, according to Peter Attia MD “pussy is low carb” something that is totally normal for a doctor to say to Epstein, who had previously been convicted of procuring a child for prostitution
Great to see this longer cut of my chat with @bigthink.com out—if you saw the first video and wished that there was a bit more detail, or if you missed it and are looking for a 20-minute intro to longevity science, check this out!
Why even the healthiest people hit a wall at age 70 | Andrew Steele
YouTube video by Big Think Clips
www.youtube.com
January 30, 2026 at 12:31 PM
Great to see this longer cut of my chat with @bigthink.com out—if you saw the first video and wished that there was a bit more detail, or if you missed it and are looking for a 20-minute intro to longevity science, check this out!
⚠️ If you’re reading this, you’ve been infected! ⚠️
Around 90% of us have been infected by the Epstein–Barr virus…and then, it lingers in our bodies for the rest of our lives.
This fascinating paper digs into some of the long-term consequences of this infection, from cancer to multiple sclerosis.
Around 90% of us have been infected by the Epstein–Barr virus…and then, it lingers in our bodies for the rest of our lives.
This fascinating paper digs into some of the long-term consequences of this infection, from cancer to multiple sclerosis.
Population-scale sequencing resolves determinants of persistent EBV DNA - Nature
Population-scale WGS reveals genetic determinants of persistent EBV DNA, linking immune regulation—especially antigen processing and MHC class II variation—to EBV persistence and heterogeneous di...
www.nature.com
January 29, 2026 at 9:32 AM
⚠️ If you’re reading this, you’ve been infected! ⚠️
Around 90% of us have been infected by the Epstein–Barr virus…and then, it lingers in our bodies for the rest of our lives.
This fascinating paper digs into some of the long-term consequences of this infection, from cancer to multiple sclerosis.
Around 90% of us have been infected by the Epstein–Barr virus…and then, it lingers in our bodies for the rest of our lives.
This fascinating paper digs into some of the long-term consequences of this infection, from cancer to multiple sclerosis.
It’s World Economic Forum week in Davos, so please do check out the video I made last time I was there!
It asks whether billionaires will live forever—and explores inequality in longevity treatments more generally too.
It also features a cameo from @ordinarythings.bsky.social!
It asks whether billionaires will live forever—and explores inequality in longevity treatments more generally too.
It also features a cameo from @ordinarythings.bsky.social!
Will billionaires live forever? (feat. @OrdinaryThings!)
YouTube video by Andrew Steele
www.youtube.com
January 20, 2026 at 8:01 AM
It’s World Economic Forum week in Davos, so please do check out the video I made last time I was there!
It asks whether billionaires will live forever—and explores inequality in longevity treatments more generally too.
It also features a cameo from @ordinarythings.bsky.social!
It asks whether billionaires will live forever—and explores inequality in longevity treatments more generally too.
It also features a cameo from @ordinarythings.bsky.social!
Reposted by Andrew Steele
In the last installment of our end-of-year series of expert roundups, we asked six prominent figures in longevity advocacy to share their thoughts on the movement’s ups and downs in 2025 and its prospects going into 2026.
lifespan.io/news/longevi... @statto.bsky.social
By: @arkadimazin.bsky.social
lifespan.io/news/longevi... @statto.bsky.social
By: @arkadimazin.bsky.social
Longevity Advocacy in 2025: The Expert Roundup
The last installment in our end-of-year series of expert roundups might be the least flashy, but it is arguably no less important than the previous […]
lifespan.io
January 16, 2026 at 2:43 PM
In the last installment of our end-of-year series of expert roundups, we asked six prominent figures in longevity advocacy to share their thoughts on the movement’s ups and downs in 2025 and its prospects going into 2026.
lifespan.io/news/longevi... @statto.bsky.social
By: @arkadimazin.bsky.social
lifespan.io/news/longevi... @statto.bsky.social
By: @arkadimazin.bsky.social
Very interesting to see @fda.gov coming out in favour of increased use of Bayesian methods in clinical trials.
This could be very beneficial—in general, I think medicine could benefit from being less binary and more Bayesian—but of course a lot depends on the priors used…
This could be very beneficial—in general, I think medicine could benefit from being less binary and more Bayesian—but of course a lot depends on the priors used…
January 15, 2026 at 2:21 PM
Very interesting to see @fda.gov coming out in favour of increased use of Bayesian methods in clinical trials.
This could be very beneficial—in general, I think medicine could benefit from being less binary and more Bayesian—but of course a lot depends on the priors used…
This could be very beneficial—in general, I think medicine could benefit from being less binary and more Bayesian—but of course a lot depends on the priors used…
Reposted by Andrew Steele
The FDA Commissioner advocating for Bayesian design and analysis is a thrill to see. www.fda.gov/news-events/... #StatsSky #Statistics #bayes #clinicaltrial #pharma #rct @fda.gov
January 15, 2026 at 1:58 PM
The FDA Commissioner advocating for Bayesian design and analysis is a thrill to see. www.fda.gov/news-events/... #StatsSky #Statistics #bayes #clinicaltrial #pharma #rct @fda.gov
How’s about we try to reduce non-age-adjusted cancer death rates by developing treatments for ageing?
Global deaths from cancer have increased, but the world has made progress against it—
January 14, 2026 at 10:57 AM
How’s about we try to reduce non-age-adjusted cancer death rates by developing treatments for ageing?
The first leukemia patient has received CAR-T cell therapy on the NHS!
Oscar’s haematologist said ‘Usually, this type of leukaemia is very aggressive and adult patients don’t live beyond six to eight months. With this therapy, we are able to offer them years and potentially a cure.’
Oscar’s haematologist said ‘Usually, this type of leukaemia is very aggressive and adult patients don’t live beyond six to eight months. With this therapy, we are able to offer them years and potentially a cure.’
First leukaemia patient to get pioneering drug on NHS says it is 'very sci-fi'
Oscar Murphy has an aggressive form of the blood cancer and is the first to get CAR-T therapy in the UK.
www.bbc.com
January 14, 2026 at 8:24 AM
The first leukemia patient has received CAR-T cell therapy on the NHS!
Oscar’s haematologist said ‘Usually, this type of leukaemia is very aggressive and adult patients don’t live beyond six to eight months. With this therapy, we are able to offer them years and potentially a cure.’
Oscar’s haematologist said ‘Usually, this type of leukaemia is very aggressive and adult patients don’t live beyond six to eight months. With this therapy, we are able to offer them years and potentially a cure.’
Reposted by Andrew Steele
Why does the word ‘longevity’ seem to be everywhere at the moment?
The final piece in our round-up of the last year in longevity looks at how ageing, wellness and biohacking cropped up in the media, pop culture and…in discussions between Putin and Xi?
Please enjoy this Friday read:
The final piece in our round-up of the last year in longevity looks at how ageing, wellness and biohacking cropped up in the media, pop culture and…in discussions between Putin and Xi?
Please enjoy this Friday read:
Netflix and immortal dictators: Longevity’s biggest year yet
From Bryan Johnson's viral biohacking to Putin and Xi discussing living to 150, 2025's biggest longevity stories—and whether hype is helping or hurting science.
thelongevityinitiative.org
January 9, 2026 at 2:33 PM
Why does the word ‘longevity’ seem to be everywhere at the moment?
The final piece in our round-up of the last year in longevity looks at how ageing, wellness and biohacking cropped up in the media, pop culture and…in discussions between Putin and Xi?
Please enjoy this Friday read:
The final piece in our round-up of the last year in longevity looks at how ageing, wellness and biohacking cropped up in the media, pop culture and…in discussions between Putin and Xi?
Please enjoy this Friday read:
Reposted by Andrew Steele
Polaris is not always the North Star. Due to Earth's precession, over the course of 26,000 years, Polaris, Alderamin, Vega, and Thuban take turns as the closest prominent star to the celestial pole.
January 7, 2026 at 10:46 PM
Polaris is not always the North Star. Due to Earth's precession, over the course of 26,000 years, Polaris, Alderamin, Vega, and Thuban take turns as the closest prominent star to the celestial pole.
Reposted by Andrew Steele
Longevity clinics grow in popularity while biohackers are hospitalised by peptide injections—and does Ozempic slow the ageing process?
We take a look at the last year in longevity medicine:
We take a look at the last year in longevity medicine:
Does Ozempic slow ageing? Plus longevity clinics, peptides
Longevity clinics take off while biohackers at RAADFest are hospitalised after unregulated peptide injections: we review 2025 in longevity medicine.
thelongevityinitiative.org
January 8, 2026 at 3:01 PM
Longevity clinics grow in popularity while biohackers are hospitalised by peptide injections—and does Ozempic slow the ageing process?
We take a look at the last year in longevity medicine:
We take a look at the last year in longevity medicine:
Remarkable result: LLMs memorise huge chunks of books verbatim, and trivial prompt engineering can encourage them to spit out the text.
This is interesting because:
• I wouldn’t necessarily have expected them to ‘store’ this much word-for-word in their structure—more pick up the ‘ideas’ from texts.
This is interesting because:
• I wouldn’t necessarily have expected them to ‘store’ this much word-for-word in their structure—more pick up the ‘ideas’ from texts.
We extracted (parts of) 12 books in experiments with 4 frontier-lab, production LLMs.
We prompted the LLMs with a short prefix of a book and asked them to complete the rest. For Harry Potter and the Sorcerer’s Stone, we extracted 95.8% of the book from jailbroken Claude 3.7 Sonnet.
We prompted the LLMs with a short prefix of a book and asked them to complete the rest. For Harry Potter and the Sorcerer’s Stone, we extracted 95.8% of the book from jailbroken Claude 3.7 Sonnet.
January 8, 2026 at 4:54 PM
Remarkable result: LLMs memorise huge chunks of books verbatim, and trivial prompt engineering can encourage them to spit out the text.
This is interesting because:
• I wouldn’t necessarily have expected them to ‘store’ this much word-for-word in their structure—more pick up the ‘ideas’ from texts.
This is interesting because:
• I wouldn’t necessarily have expected them to ‘store’ this much word-for-word in their structure—more pick up the ‘ideas’ from texts.
‘The fact that people with obesity rebound more slowly on some other program nobody is offering you and which doesn’t scale is irrelevant and highlighting it is basically a sort of moral judgement on the failure of one billion people.’
Great piece.
Great piece.
If you stop taking blood pressure meds, your BP goes up. We call that medicine. If you stop taking GLP-1s, your weight goes up. Scientists are calling it "weight recidivism"—a term for convicted criminals.
Why is obesity still treated as a moral failure?
open.substack.com/pub/overmatt...
Why is obesity still treated as a moral failure?
open.substack.com/pub/overmatt...
The moral panic about GLP-1 rebound
Scientists and journalists are piling on the misery about the weight regain after medication
open.substack.com
January 8, 2026 at 4:40 PM
‘The fact that people with obesity rebound more slowly on some other program nobody is offering you and which doesn’t scale is irrelevant and highlighting it is basically a sort of moral judgement on the failure of one billion people.’
Great piece.
Great piece.
Reposted by Andrew Steele
Excited to see this develop 🙌🏻 Super initiative, punchy and engaging pieces, and big vision. Wouldn't expect anything else from @statto.bsky.social! 👏🏼
Go strong!
Go strong!
Hi! We are The Longevity Initiative, a new think tank and educational organisation working towards a world free from age-related disease, where longevity medicines are accessible to everyone.
Find out more at our website, thelongevityinitiative.org 🐢
Find out more at our website, thelongevityinitiative.org 🐢
The Longevity Initiative
Learn how longevity science could help us all live healthier for longer—and what extending healthspan means for policy, ageing, and the economy.
thelongevityinitiative.org
January 7, 2026 at 5:51 PM
Excited to see this develop 🙌🏻 Super initiative, punchy and engaging pieces, and big vision. Wouldn't expect anything else from @statto.bsky.social! 👏🏼
Go strong!
Go strong!
Checking something in my book and came across this note…I’m proud of past-me for including this pedantry!
The statistic it’s referring to is ‘A 20-year-old today has better odds of having a living grandmother than a 20-year-old in the 1800s did of having a living mother.’
The statistic it’s referring to is ‘A 20-year-old today has better odds of having a living grandmother than a 20-year-old in the 1800s did of having a living mother.’
January 7, 2026 at 10:06 AM
Checking something in my book and came across this note…I’m proud of past-me for including this pedantry!
The statistic it’s referring to is ‘A 20-year-old today has better odds of having a living grandmother than a 20-year-old in the 1800s did of having a living mother.’
The statistic it’s referring to is ‘A 20-year-old today has better odds of having a living grandmother than a 20-year-old in the 1800s did of having a living mother.’
Reposted by Andrew Steele
Live longer, hopefully healthier?
Check out our first news article from @thelongevityinitiative.org: a round-up of longevity science in 2025!
There will be more posts this week on longevity in business, research funding, medicine and comms and policy (Netflix docs and Putin hot-mics, anyone?) so please follow to be first to hear!
There will be more posts this week on longevity in business, research funding, medicine and comms and policy (Netflix docs and Putin hot-mics, anyone?) so please follow to be first to hear!
To kick off 2026, we’re publishing a week of articles looking back at 2025 in longevity.
The first is 2025 in longevity science—two new drug cocktails make mice live longer, plus clocks to measure the age of your organs and ‘extracellular vesicles’ improve signs of ageing in monkeys.
Read it here:
The first is 2025 in longevity science—two new drug cocktails make mice live longer, plus clocks to measure the age of your organs and ‘extracellular vesicles’ improve signs of ageing in monkeys.
Read it here:
January 6, 2026 at 5:02 PM
Live longer, hopefully healthier?
Reposted by Andrew Steele
Billion-dollar bets on cellular reprogramming, biotech's rough year, and early FDA success for healthy lifespan extension in dogs.
The biggest business news in longevity in the last year:
The biggest business news in longevity in the last year:
The business of longevity in 2025: big bets amid biotech bust
Billion-dollar bets on cellular reprogramming, biotech's rough year, and early FDA success for healthy lifespan extension in dogs.
thelongevityinitiative.org
January 6, 2026 at 4:04 PM
Billion-dollar bets on cellular reprogramming, biotech's rough year, and early FDA success for healthy lifespan extension in dogs.
The biggest business news in longevity in the last year:
The biggest business news in longevity in the last year:
Check out our first news article from @thelongevityinitiative.org: a round-up of longevity science in 2025!
There will be more posts this week on longevity in business, research funding, medicine and comms and policy (Netflix docs and Putin hot-mics, anyone?) so please follow to be first to hear!
There will be more posts this week on longevity in business, research funding, medicine and comms and policy (Netflix docs and Putin hot-mics, anyone?) so please follow to be first to hear!
To kick off 2026, we’re publishing a week of articles looking back at 2025 in longevity.
The first is 2025 in longevity science—two new drug cocktails make mice live longer, plus clocks to measure the age of your organs and ‘extracellular vesicles’ improve signs of ageing in monkeys.
Read it here:
The first is 2025 in longevity science—two new drug cocktails make mice live longer, plus clocks to measure the age of your organs and ‘extracellular vesicles’ improve signs of ageing in monkeys.
Read it here:
2025 in longevity: mice live 30% longer, human organ clocks
Two new drug cocktails make mice live longer—plus clocks to measure the age of your organs, and ‘extracellular vesicles’ improve signs of ageing in monkeys.
thelongevityinitiative.org
January 5, 2026 at 4:41 PM
Check out our first news article from @thelongevityinitiative.org: a round-up of longevity science in 2025!
There will be more posts this week on longevity in business, research funding, medicine and comms and policy (Netflix docs and Putin hot-mics, anyone?) so please follow to be first to hear!
There will be more posts this week on longevity in business, research funding, medicine and comms and policy (Netflix docs and Putin hot-mics, anyone?) so please follow to be first to hear!
The future of health depends on longevity science.
Progress in science depends on better policy, regulation and funding—that’s why I founded @thelongevityinitiative.org with @kshoylev.bsky.social.
Help us build the infrastructure for improved longevity policy and education in 2026.
Link below 👇
Progress in science depends on better policy, regulation and funding—that’s why I founded @thelongevityinitiative.org with @kshoylev.bsky.social.
Help us build the infrastructure for improved longevity policy and education in 2026.
Link below 👇
December 31, 2025 at 6:51 PM
The future of health depends on longevity science.
Progress in science depends on better policy, regulation and funding—that’s why I founded @thelongevityinitiative.org with @kshoylev.bsky.social.
Help us build the infrastructure for improved longevity policy and education in 2026.
Link below 👇
Progress in science depends on better policy, regulation and funding—that’s why I founded @thelongevityinitiative.org with @kshoylev.bsky.social.
Help us build the infrastructure for improved longevity policy and education in 2026.
Link below 👇
Reposted by Andrew Steele
There are just hours of 2025 remaining…so it’s your last chance to support The LI before the end of the tax year!
Donations intended to support @thelongevityinitiative.org can be made via Vitalism Charitable Foundation, a 501(c)(3) nonprofit.
Donate here:
Donations intended to support @thelongevityinitiative.org can be made via Vitalism Charitable Foundation, a 501(c)(3) nonprofit.
Donate here:
Donate – The Longevity Initiative
Help us build a future of longevity, healthier lives for all with longevity education and policy.
thelongevityinitiative.org
December 31, 2025 at 3:34 PM
There are just hours of 2025 remaining…so it’s your last chance to support The LI before the end of the tax year!
Donations intended to support @thelongevityinitiative.org can be made via Vitalism Charitable Foundation, a 501(c)(3) nonprofit.
Donate here:
Donations intended to support @thelongevityinitiative.org can be made via Vitalism Charitable Foundation, a 501(c)(3) nonprofit.
Donate here:
Reposted by Andrew Steele
The majority of poor health and deaths globally are caused by diseases that become common with age.
But public policy has yet to catch up with ageing science, and longevity research is underappreciated, and underfunded.
We exist to change that.
Support us here:
But public policy has yet to catch up with ageing science, and longevity research is underappreciated, and underfunded.
We exist to change that.
Support us here:
Donate – The Longevity Initiative
Help us build a future of longevity, healthier lives for all with longevity education and policy.
thelongevityinitiative.org
December 31, 2025 at 12:41 PM
The majority of poor health and deaths globally are caused by diseases that become common with age.
But public policy has yet to catch up with ageing science, and longevity research is underappreciated, and underfunded.
We exist to change that.
Support us here:
But public policy has yet to catch up with ageing science, and longevity research is underappreciated, and underfunded.
We exist to change that.
Support us here:
Things you can do to live a longer, healthier life:
1. Eat a balanced diet
2. Exercise
3. Follow @thelongevityinitiative.org
4. Sign up for our newsletter at thelongevityinitiative.org/news/
5. Tell friends and family to do the same (because living a long, healthy life will be no fun without them!)
1. Eat a balanced diet
2. Exercise
3. Follow @thelongevityinitiative.org
4. Sign up for our newsletter at thelongevityinitiative.org/news/
5. Tell friends and family to do the same (because living a long, healthy life will be no fun without them!)
News – The Longevity Initiative
thelongevityinitiative.org
December 30, 2025 at 2:18 PM
Things you can do to live a longer, healthier life:
1. Eat a balanced diet
2. Exercise
3. Follow @thelongevityinitiative.org
4. Sign up for our newsletter at thelongevityinitiative.org/news/
5. Tell friends and family to do the same (because living a long, healthy life will be no fun without them!)
1. Eat a balanced diet
2. Exercise
3. Follow @thelongevityinitiative.org
4. Sign up for our newsletter at thelongevityinitiative.org/news/
5. Tell friends and family to do the same (because living a long, healthy life will be no fun without them!)