Andrew Steele
@statto.bsky.social
Ageing biologist (aren’t we all?)
My book: https://ageless.link/
My videos: https://www.youtube.com/DrAndrewSteele
My website: https://andrewsteele.co.uk/
Location: Berlin, DE
My book: https://ageless.link/
My videos: https://www.youtube.com/DrAndrewSteele
My website: https://andrewsteele.co.uk/
Location: Berlin, DE
And, of course, AI can help with both of these and more. There’s a huge amount of potential here and I’m definitely going to explore some ideas!
November 14, 2025 at 8:31 AM
And, of course, AI can help with both of these and more. There’s a huge amount of potential here and I’m definitely going to explore some ideas!
It was a pleasure to attend the EHiN conference in Oslo this week and talk longevity with e-health experts.
The second picture is me signing a copy of Ageless for the Norwegian Health Minister, Jan Christian Vestre! (I also signed a copy for Danish Ældreminister Mette Kierkegaard but no pic sadly!)
The second picture is me signing a copy of Ageless for the Norwegian Health Minister, Jan Christian Vestre! (I also signed a copy for Danish Ældreminister Mette Kierkegaard but no pic sadly!)
November 14, 2025 at 8:28 AM
It was a pleasure to attend the EHiN conference in Oslo this week and talk longevity with e-health experts.
The second picture is me signing a copy of Ageless for the Norwegian Health Minister, Jan Christian Vestre! (I also signed a copy for Danish Ældreminister Mette Kierkegaard but no pic sadly!)
The second picture is me signing a copy of Ageless for the Norwegian Health Minister, Jan Christian Vestre! (I also signed a copy for Danish Ældreminister Mette Kierkegaard but no pic sadly!)
Today I’m at a big Norwegian medical conference, and they’ve bought a copy of my book for every speaker!
Thanks, EHiN!
Thanks, EHiN!
November 11, 2025 at 9:12 AM
Today I’m at a big Norwegian medical conference, and they’ve bought a copy of my book for every speaker!
Thanks, EHiN!
Thanks, EHiN!
Including an article on longevity science and scams by some guy called Andrew Steele…
October 2, 2025 at 5:29 PM
Including an article on longevity science and scams by some guy called Andrew Steele…
(The reason it’s ultra-wide is that they filmed it on an anamorphic lens usually used in movies…I think it looks amazing!)
October 2, 2025 at 11:16 AM
(The reason it’s ultra-wide is that they filmed it on an anamorphic lens usually used in movies…I think it looks amazing!)
New ITP paper just dropped! 🧪 #longevityscience
• Epicatechin, a flavanol found in cocoa, increased average lifespan by 5% in male mice.
• Halofuginone, a compound that simulates protein restriction, +9%, again only in males.
• Mitoglitazone, an experimental diabetes drug, also +9% in males only.
• Epicatechin, a flavanol found in cocoa, increased average lifespan by 5% in male mice.
• Halofuginone, a compound that simulates protein restriction, +9%, again only in males.
• Mitoglitazone, an experimental diabetes drug, also +9% in males only.
September 22, 2025 at 12:47 PM
New ITP paper just dropped! 🧪 #longevityscience
• Epicatechin, a flavanol found in cocoa, increased average lifespan by 5% in male mice.
• Halofuginone, a compound that simulates protein restriction, +9%, again only in males.
• Mitoglitazone, an experimental diabetes drug, also +9% in males only.
• Epicatechin, a flavanol found in cocoa, increased average lifespan by 5% in male mice.
• Halofuginone, a compound that simulates protein restriction, +9%, again only in males.
• Mitoglitazone, an experimental diabetes drug, also +9% in males only.
Here’s a taster of the new podcast from @crick.ac.uk.
Do check out the full episode—it’s my dream panel of brilliant longevity experts, Profs Linda Partridge and Lynne Cox, Brian Cox hosting, and Paul Nurse who I think has a Nobel Prize or something? (And is also Director of The Crick.)
Do check out the full episode—it’s my dream panel of brilliant longevity experts, Profs Linda Partridge and Lynne Cox, Brian Cox hosting, and Paul Nurse who I think has a Nobel Prize or something? (And is also Director of The Crick.)
September 17, 2025 at 2:37 PM
Here’s a taster of the new podcast from @crick.ac.uk.
Do check out the full episode—it’s my dream panel of brilliant longevity experts, Profs Linda Partridge and Lynne Cox, Brian Cox hosting, and Paul Nurse who I think has a Nobel Prize or something? (And is also Director of The Crick.)
Do check out the full episode—it’s my dream panel of brilliant longevity experts, Profs Linda Partridge and Lynne Cox, Brian Cox hosting, and Paul Nurse who I think has a Nobel Prize or something? (And is also Director of The Crick.)
When I asked Google’s Gemini to ‘show thinking’ it seemed to be thinking the quiet part out loud…
September 3, 2025 at 9:45 PM
When I asked Google’s Gemini to ‘show thinking’ it seemed to be thinking the quiet part out loud…
If Xi and Putin want to live to 150, I would suggest they invest a decent fraction of their countries’ GDPs into longevity research.
September 3, 2025 at 6:27 PM
If Xi and Putin want to live to 150, I would suggest they invest a decent fraction of their countries’ GDPs into longevity research.
Big props to MILES Car & Van Sharing—I got in touch with their customer support because the app didn’t work on @grapheneos.org, ended up chatting with someone who was considering the switch to Graphene (!!) and…the developers have now updated the app to work on secure phones!
August 22, 2025 at 10:42 AM
Big props to MILES Car & Van Sharing—I got in touch with their customer support because the app didn’t work on @grapheneos.org, ended up chatting with someone who was considering the switch to Graphene (!!) and…the developers have now updated the app to work on secure phones!
I think the problem here is that they’re giving it pretty healthcare-expert worded input so it’s not surprising to me that the best next words to predict are more sensible than the example I tried.
Also, none of the bits of HealthBench seem to relate to general health advice.
Also, none of the bits of HealthBench seem to relate to general health advice.
July 20, 2025 at 1:44 PM
I think the problem here is that they’re giving it pretty healthcare-expert worded input so it’s not surprising to me that the best next words to predict are more sensible than the example I tried.
Also, none of the bits of HealthBench seem to relate to general health advice.
Also, none of the bits of HealthBench seem to relate to general health advice.
Then I told it I didn’t want to lower my cholesterol…and it validated my concerns, going hard against expert consensus!
(Check the link above for its full answer if you’re interested—but it was basically wellness grifter talking points.)
(Check the link above for its full answer if you’re interested—but it was basically wellness grifter talking points.)
July 20, 2025 at 1:38 PM
Then I told it I didn’t want to lower my cholesterol…and it validated my concerns, going hard against expert consensus!
(Check the link above for its full answer if you’re interested—but it was basically wellness grifter talking points.)
(Check the link above for its full answer if you’re interested—but it was basically wellness grifter talking points.)
Then, the supplements themselves… The evidence for omega-3 is pretty borderline, CoQ10 and magnesium even moreso…and it’s only at 4 and 5 that it starts giving evidence-based recommendations.
And the rest of the list is essentially BS! Garlic extract?! Resveratrol?!?
And the rest of the list is essentially BS! Garlic extract?! Resveratrol?!?
July 20, 2025 at 1:37 PM
Then, the supplements themselves… The evidence for omega-3 is pretty borderline, CoQ10 and magnesium even moreso…and it’s only at 4 and 5 that it starts giving evidence-based recommendations.
And the rest of the list is essentially BS! Garlic extract?! Resveratrol?!?
And the rest of the list is essentially BS! Garlic extract?! Resveratrol?!?
Right at the top of this answer, it should say ‘supplements probably won’t help heart health, other factors like diet and exercise are more important for most people’. It should give caveats about your medical history and family history… But no, straight in with supplements!
July 20, 2025 at 1:37 PM
Right at the top of this answer, it should say ‘supplements probably won’t help heart health, other factors like diet and exercise are more important for most people’. It should give caveats about your medical history and family history… But no, straight in with supplements!
According to @economist.com, web search traffic is down over the last couple of years—due to people turning to AI rather than Google
The search category falling the fastest is health—and that worries me, because I don’t think AI is ready for the prime-time here. 🧪 #health #ai
THREAD INCOMING
The search category falling the fastest is health—and that worries me, because I don’t think AI is ready for the prime-time here. 🧪 #health #ai
THREAD INCOMING
July 20, 2025 at 1:33 PM
According to @economist.com, web search traffic is down over the last couple of years—due to people turning to AI rather than Google
The search category falling the fastest is health—and that worries me, because I don’t think AI is ready for the prime-time here. 🧪 #health #ai
THREAD INCOMING
The search category falling the fastest is health—and that worries me, because I don’t think AI is ready for the prime-time here. 🧪 #health #ai
THREAD INCOMING
July: complete! 7/12ths done. :)
Today and tomorrow are like the only sunny days last week or this. I did *not* expect July to be the month where finding a sunny day would be tough! But Berlin summer this year has left something to be desired…
Today and tomorrow are like the only sunny days last week or this. I did *not* expect July to be the month where finding a sunny day would be tough! But Berlin summer this year has left something to be desired…
July 19, 2025 at 12:43 PM
July: complete! 7/12ths done. :)
Today and tomorrow are like the only sunny days last week or this. I did *not* expect July to be the month where finding a sunny day would be tough! But Berlin summer this year has left something to be desired…
Today and tomorrow are like the only sunny days last week or this. I did *not* expect July to be the month where finding a sunny day would be tough! But Berlin summer this year has left something to be desired…
.@scheibyeknudsenlab.bsky.social tells Longevity Summit Dublin that how old you look is a remarkably good predictor of risk of death: 30,000 hospital admissions had their photo taken and those survival curves in the bottom right show huge differences in survival in people with different facial ages!
July 4, 2025 at 11:34 AM
.@scheibyeknudsenlab.bsky.social tells Longevity Summit Dublin that how old you look is a remarkably good predictor of risk of death: 30,000 hospital admissions had their photo taken and those survival curves in the bottom right show huge differences in survival in people with different facial ages!
I’ve just noticed that, if you don’t want Meta AI to go through slurping up all your WhatsApp messages, you have to go through and turn this on *for every chat you’re in*.
Can everyone please move to @signal.org already? This is getting absurd!
Can everyone please move to @signal.org already? This is getting absurd!
June 26, 2025 at 9:21 AM
I’ve just noticed that, if you don’t want Meta AI to go through slurping up all your WhatsApp messages, you have to go through and turn this on *for every chat you’re in*.
Can everyone please move to @signal.org already? This is getting absurd!
Can everyone please move to @signal.org already? This is getting absurd!
With the solstice yesterday, I am now half-way through a photo project: take a picture from this exact spot every month in 2025!
This is January–June, each picture taken as close to the 21st as weather and my being in Berlin allows.
Can’t wait to find out what happens next!
This is January–June, each picture taken as close to the 21st as weather and my being in Berlin allows.
Can’t wait to find out what happens next!
June 22, 2025 at 8:29 AM
With the solstice yesterday, I am now half-way through a photo project: take a picture from this exact spot every month in 2025!
This is January–June, each picture taken as close to the 21st as weather and my being in Berlin allows.
Can’t wait to find out what happens next!
This is January–June, each picture taken as close to the 21st as weather and my being in Berlin allows.
Can’t wait to find out what happens next!
The days will start getting shorter…
…wait for it…
…now!
Summer solstice 2025, June 21st, 02:42 UTC (03:42 BST, 04:42 CEST).
This means the sun will be higher and brighter today than any other day this year—so, UV me says: wear your sunscreen!
…wait for it…
…now!
Summer solstice 2025, June 21st, 02:42 UTC (03:42 BST, 04:42 CEST).
This means the sun will be higher and brighter today than any other day this year—so, UV me says: wear your sunscreen!
June 21, 2025 at 2:42 AM
The days will start getting shorter…
…wait for it…
…now!
Summer solstice 2025, June 21st, 02:42 UTC (03:42 BST, 04:42 CEST).
This means the sun will be higher and brighter today than any other day this year—so, UV me says: wear your sunscreen!
…wait for it…
…now!
Summer solstice 2025, June 21st, 02:42 UTC (03:42 BST, 04:42 CEST).
This means the sun will be higher and brighter today than any other day this year—so, UV me says: wear your sunscreen!
Bonjour, Paris!
Cycled to a breakfast meeting (amazing way to commute and see the city!), now to chat longevity science and AI at the @himssglobal.bsky.social conference!
Cycled to a breakfast meeting (amazing way to commute and see the city!), now to chat longevity science and AI at the @himssglobal.bsky.social conference!
June 12, 2025 at 10:31 AM
Bonjour, Paris!
Cycled to a breakfast meeting (amazing way to commute and see the city!), now to chat longevity science and AI at the @himssglobal.bsky.social conference!
Cycled to a breakfast meeting (amazing way to commute and see the city!), now to chat longevity science and AI at the @himssglobal.bsky.social conference!
It’s an interesting question, but a challenging one to answer: with three drugs, trying a few different doses of each in combination results in very big experiments, very fast. eg trying three different doses of each in combination would be 27 separate experiments!
May 30, 2025 at 10:29 AM
It’s an interesting question, but a challenging one to answer: with three drugs, trying a few different doses of each in combination results in very big experiments, very fast. eg trying three different doses of each in combination would be 27 separate experiments!
Previous top-performing rapamycin + something combos were diabetes drugs acarbose and metformin, as you can see from this graph from LEVF’s RAID database:
May 30, 2025 at 10:27 AM
Previous top-performing rapamycin + something combos were diabetes drugs acarbose and metformin, as you can see from this graph from LEVF’s RAID database:
Rapamycin makes cells think the animal is eating less food, causing recycling of old and broken cellular components. But rapa only hits one of the cells’ nutrient sensors, so the idea is to stop compensatory ‘huh, there is food really!’ signals getting through by another route.
May 30, 2025 at 10:26 AM
Rapamycin makes cells think the animal is eating less food, causing recycling of old and broken cellular components. But rapa only hits one of the cells’ nutrient sensors, so the idea is to stop compensatory ‘huh, there is food really!’ signals getting through by another route.
New 30% mouse lifespan extension paper just dropped! 🧪 #aging #longevity
Another example of rapamycin + something increasing mouse lifespan more than rapamycin or something alone.
In this case, the something is trametinib, an anti-cancer drug:
Another example of rapamycin + something increasing mouse lifespan more than rapamycin or something alone.
In this case, the something is trametinib, an anti-cancer drug:
May 30, 2025 at 10:26 AM
New 30% mouse lifespan extension paper just dropped! 🧪 #aging #longevity
Another example of rapamycin + something increasing mouse lifespan more than rapamycin or something alone.
In this case, the something is trametinib, an anti-cancer drug:
Another example of rapamycin + something increasing mouse lifespan more than rapamycin or something alone.
In this case, the something is trametinib, an anti-cancer drug: