Signe Mežinska
@signemezinska.bsky.social
Bioethics, medical ethics and research ethics/integrity. Associate professor at the University of Latvia. FAMILY project https://family-project.eu/, BEYOND project https://beyondbadapples.eu/, TRUSTPARENCY project https://trustparency-project.eu/
Pinned
Signe Mežinska
@signemezinska.bsky.social
· May 12
ROSiE Case Collection: Responsible Open Science
This is a case collection for the ROSiE Training Materials for Responsible Open Science. Many cases included in this material are used in the ROSiE traditional and online training materials; however, ...
zenodo.org
The ROSiE Case Collection is a rich resource for exploring ethical issues in open science.
- Case studies + discussion questions
- Index by topic, field & research stage
🎞️ Animations for 6 cases!
🔗 Case Collection: zenodo.org/records/1079...
▶️ Animations: www.youtube.com/@rosieprojec...
- Case studies + discussion questions
- Index by topic, field & research stage
🎞️ Animations for 6 cases!
🔗 Case Collection: zenodo.org/records/1079...
▶️ Animations: www.youtube.com/@rosieprojec...
Great reading: "But the kids know, and they know that the other kids know, and they know that we don’t know shit. Children have always looked for a world without us. With the advent of the Internet, they have found one lying in the rubble." unpublishablepapers.substack.com/p/where-do-t...
Where Do the Children Play?
On the need for a world without us
unpublishablepapers.substack.com
November 15, 2025 at 11:52 AM
Great reading: "But the kids know, and they know that the other kids know, and they know that we don’t know shit. Children have always looked for a world without us. With the advent of the Internet, they have found one lying in the rubble." unpublishablepapers.substack.com/p/where-do-t...
JVLMA zinātniskā un radošā darba prorektore Diāna Zandberga līdz galam nesaprot studētāju mērķus:"Lūk, visi ieraudzīja tikai šo naudas summu, un tas kļuva par to varbūt pat mērķi, jo citus gadus visi stājās ar domu attīstīt sevi, sasniegt augstākus mākslinieciskus mērķus." www.lsm.lv/raksts/kultu...
Mūzikas akadēmija uzņem doktorantus bez finansējuma likumā paredzētajam atalgojumam
Jāzepa Vītola Latvijas Mūzikas akadēmija (JVLMA) uzņēmusi budžeta grupā doktorantus, pirms tam neaprēķinot, cik daudziem spēs maksāt 1000 eiro atalgojumu mēnesī, kā to nosaka jaunais doktorantūras mod...
www.lsm.lv
November 14, 2025 at 8:28 PM
JVLMA zinātniskā un radošā darba prorektore Diāna Zandberga līdz galam nesaprot studētāju mērķus:"Lūk, visi ieraudzīja tikai šo naudas summu, un tas kļuva par to varbūt pat mērķi, jo citus gadus visi stājās ar domu attīstīt sevi, sasniegt augstākus mākslinieciskus mērķus." www.lsm.lv/raksts/kultu...
Maastricht University has withdrawn a 2022 news release that claimed overweight and obesity cost Dutch society 79 billion euros annually, due to a calculation error. Additionally, questions have been raised about undisclosed conflicts of interest. nltimes.nl/2025/11/11/m...
Maastricht Uni retracts €79 billion obesity cost claim over conflict-of-interest
Maastricht University has withdrawn a 2022 news release claiming that overweight and obesity cost Dutch society 79 billion euros annually, after investigations revealed the figure was significantly in...
nltimes.nl
November 12, 2025 at 11:16 AM
Maastricht University has withdrawn a 2022 news release that claimed overweight and obesity cost Dutch society 79 billion euros annually, due to a calculation error. Additionally, questions have been raised about undisclosed conflicts of interest. nltimes.nl/2025/11/11/m...
This is alarming and unacceptable. Europe continues to uphold a strong ethical stance on embryo editing, while the US remains worryingly unpredictable. www.technologyreview.com/2025/10/31/1...
Here’s the latest company planning for gene-edited babies
Entrepreneurs say it’s time to safety-test designer baby technology.
www.technologyreview.com
November 9, 2025 at 8:02 AM
This is alarming and unacceptable. Europe continues to uphold a strong ethical stance on embryo editing, while the US remains worryingly unpredictable. www.technologyreview.com/2025/10/31/1...
Reposted by Signe Mežinska
⚖️ Signe Mežinska shared updates and new plans from Work Package 8: Ethical aspects and social consequences of intergenerational transmission of risk and prediction of mental illness.
@signemezinska.bsky.social @ivarsneiders.bsky.social
@signemezinska.bsky.social @ivarsneiders.bsky.social
November 7, 2025 at 10:45 AM
⚖️ Signe Mežinska shared updates and new plans from Work Package 8: Ethical aspects and social consequences of intergenerational transmission of risk and prediction of mental illness.
@signemezinska.bsky.social @ivarsneiders.bsky.social
@signemezinska.bsky.social @ivarsneiders.bsky.social
Reposted by Signe Mežinska
Man šķiet, ka uz visiem iebildumiem pret pretvardarbības konvenciju vislabāko atbildi sniedza labklājības ministrs Uldis Augulis pirms nieka diviem gadiem (no 4. minūtes). Šo tagad vajadzētu uz katra stūra nonstopā atskaņot.
replay.lsm.lv/lv/skaties/i...
replay.lsm.lv/lv/skaties/i...
Intervija ar labklājības ministru Uldi Auguli - REplay.lv
Ministru kabinets ārkārtas sēdē akceptēja 2024. gada valsts budžeta projektu un to pavadošos likumprojektus. Prioritātes nākamgad ir drošība, izglītība un veselība.Par to saruna ar labklājības ministr...
replay.lsm.lv
November 2, 2025 at 2:03 PM
Man šķiet, ka uz visiem iebildumiem pret pretvardarbības konvenciju vislabāko atbildi sniedza labklājības ministrs Uldis Augulis pirms nieka diviem gadiem (no 4. minūtes). Šo tagad vajadzētu uz katra stūra nonstopā atskaņot.
replay.lsm.lv/lv/skaties/i...
replay.lsm.lv/lv/skaties/i...
Reposted by Signe Mežinska
Sometimes it is not only about values, but also about optics. In Latvia we discuss local political gambles behind yesterday's vote for the country to leave the Istanbul Convention, from the outside, it is clear - Latvia follows Hungary, Slovakia and other countries that head East.
October 31, 2025 at 2:10 PM
Sometimes it is not only about values, but also about optics. In Latvia we discuss local political gambles behind yesterday's vote for the country to leave the Istanbul Convention, from the outside, it is clear - Latvia follows Hungary, Slovakia and other countries that head East.
Aizgāju gulēt Latvijā, pamodos Ungārijā. (Patiesībā jau sagaidīju balsojumu).
October 31, 2025 at 5:24 AM
Aizgāju gulēt Latvijā, pamodos Ungārijā. (Patiesībā jau sagaidīju balsojumu).
Šis ir ļoti satraucoši - pacientu drošības ignorēšana, pārprasta lojalitāte profesionālajā vidē un "gan jau būs labi" attieksme.
Nopietnu pārkāpumu un zināšanu trūkuma dēļ Somijā atņemtas tiesības praktizēt ārsta profesijā, bet tas neliedz Latvijā tikt pie amata reģionālajās slimnīcās vai arī savas ārsta prakses kādā no pašvaldības iestādēm.
🖥️ youtu.be/us5ooFYkc1A
🖥️ youtu.be/us5ooFYkc1A
October 28, 2025 at 9:33 AM
Šis ir ļoti satraucoši - pacientu drošības ignorēšana, pārprasta lojalitāte profesionālajā vidē un "gan jau būs labi" attieksme.
"Sorbonne University plans to leave the Times Higher Education (THE) Rankings [..] most of these rankings are “black boxes” whose methods not only raise ethical questions but also fail to cover the breadth and diversity of university contributions." sciencebusiness.net/news/univers...
Why Sorbonne pulled out of university ranking
France’s Sorbonne University plans to leave the Times Higher Education (THE) Rankings, adding its name to a growing number of universities rejecting lists that play one institution off against another...
sciencebusiness.net
October 20, 2025 at 6:57 PM
"Sorbonne University plans to leave the Times Higher Education (THE) Rankings [..] most of these rankings are “black boxes” whose methods not only raise ethical questions but also fail to cover the breadth and diversity of university contributions." sciencebusiness.net/news/univers...
Reposted by Signe Mežinska
"About 67% of all antidepressant and antipsychotic treatment episodes in the 700 included patients (mean age = 14.6 years, girls = 67%) were off-label."
link.springer.com/article/10.1...
link.springer.com/article/10.1...
Off-label drug use in children and adolescents treated with antidepressants and antipsychotics: results from a prospective multicenter trial - Child and Adolescent Psychiatry and Mental Health
Background/Objectives Off-label psychopharmacologic medication use is widespread in child and adolescent psychiatry, but little is known about its associated factors. This study aimed to assess freque...
link.springer.com
October 16, 2025 at 7:56 AM
"About 67% of all antidepressant and antipsychotic treatment episodes in the 700 included patients (mean age = 14.6 years, girls = 67%) were off-label."
link.springer.com/article/10.1...
link.springer.com/article/10.1...
Just a fact: During the 2024-2025 school year, PEN America recorded 6,870 instances of book bans across 23 states and 87 public school districts. pen.org/report/the-n...
The Normalization of Book Banning
This report offers a window into the complex and extensive climate of censorship between July 1, 2024 through June 30, 2025.
pen.org
October 15, 2025 at 12:31 PM
Just a fact: During the 2024-2025 school year, PEN America recorded 6,870 instances of book bans across 23 states and 87 public school districts. pen.org/report/the-n...
Reposted by Signe Mežinska
It occurred to me that we need Contributor Statements (like CRediT), except to describe various uses of Gen-AI in research. But like all decent thoughts, someone else had it first. I really like what this group has done. Their tool is useful: www.leidenmadtrics.nl/articles/gai...
#researchintegrity
#researchintegrity
GAIDeT: a practical taxonomy for declaring AI use in research and publishing
Transparency of AI use in academia matters for authors, editors, reviewers, readers and repository moderators. This blog post introduces GAIDeT, a taxonomy for the structured disclosure of Generative ...
www.leidenmadtrics.nl
October 14, 2025 at 10:35 PM
It occurred to me that we need Contributor Statements (like CRediT), except to describe various uses of Gen-AI in research. But like all decent thoughts, someone else had it first. I really like what this group has done. Their tool is useful: www.leidenmadtrics.nl/articles/gai...
#researchintegrity
#researchintegrity
Noteikti vērts noklausīties, lai labāk saprastu zinātnes būtību replay.lsm.lv/lv/klausies/...
Krustpunktā Lielā intervija: LU tenūrprofesors Vjačeslavs Kaščejevs - REplay.lv
Tematus, ko apspriest politiķi spēj atrast un mainīt zibens ātrumā. Vēl pirms īsa brīža šķēpi tika lauzti par fundamentālajiem pētījumiem zinātnē. Kā šajā situācija jūtas zinātnieki? Krustpunktā sarun...
replay.lsm.lv
October 7, 2025 at 4:12 PM
Noteikti vērts noklausīties, lai labāk saprastu zinātnes būtību replay.lsm.lv/lv/klausies/...
Reposted by Signe Mežinska
Recent MDPI paper including diagram of a bacterial cell with a mitochondrion 🤦♀️ The authors propose a mechanism for the toxicity of silver nanoparticles: "Ag+ ions in AgNPs bombard the bacterial mitochondria’s electron transport chain, resulting in cell death".
October 5, 2025 at 7:56 PM
Recent MDPI paper including diagram of a bacterial cell with a mitochondrion 🤦♀️ The authors propose a mechanism for the toxicity of silver nanoparticles: "Ag+ ions in AgNPs bombard the bacterial mitochondria’s electron transport chain, resulting in cell death".
Reposted by Signe Mežinska
Research: low productivity gains from AI may stem from employees using AI to produce "workslop", or low-effort, passable work that creates more work for others (Harvard Business Review)
Main Link | Techmeme Permalink
Main Link | Techmeme Permalink
September 23, 2025 at 8:30 AM
Research: low productivity gains from AI may stem from employees using AI to produce "workslop", or low-effort, passable work that creates more work for others (Harvard Business Review)
Main Link | Techmeme Permalink
Main Link | Techmeme Permalink
Reposted by Signe Mežinska
Can large language models stand in for human participants?
Many social scientists seem to think so, and are already using "silicon samples" in research.
One problem: depending on the analytic decisions made, you can basically get these samples to show any effect you want.
THREAD 🧵
Many social scientists seem to think so, and are already using "silicon samples" in research.
One problem: depending on the analytic decisions made, you can basically get these samples to show any effect you want.
THREAD 🧵
The threat of analytic flexibility in using large language models to simulate human data: A call to attention
Social scientists are now using large language models to create "silicon samples" - synthetic datasets intended to stand in for human respondents, aimed at revolutionising human subjects research. How...
arxiv.org
September 18, 2025 at 7:56 AM
Can large language models stand in for human participants?
Many social scientists seem to think so, and are already using "silicon samples" in research.
One problem: depending on the analytic decisions made, you can basically get these samples to show any effect you want.
THREAD 🧵
Many social scientists seem to think so, and are already using "silicon samples" in research.
One problem: depending on the analytic decisions made, you can basically get these samples to show any effect you want.
THREAD 🧵
Šodien gadījās runāt ar senioriem par pacientu tiesībām veselības aprūpē. Nekādi nepamet sajūta, cik ļoti aplami, ja jāstāsta senioriem par to, kā viņiem labāk aizstāvēt savas tiesības situācijās, kurās visu iesaistīto neapšaubāms pienākums jau sākotnēji būtu nodrošināt šo tiesību īstenošanu.
September 17, 2025 at 1:52 PM
Šodien gadījās runāt ar senioriem par pacientu tiesībām veselības aprūpē. Nekādi nepamet sajūta, cik ļoti aplami, ja jāstāsta senioriem par to, kā viņiem labāk aizstāvēt savas tiesības situācijās, kurās visu iesaistīto neapšaubāms pienākums jau sākotnēji būtu nodrošināt šo tiesību īstenošanu.
Reposted by Signe Mežinska
This is another wake-up call about what is happening with scientific literature, which is being flooded by template papers produced by paper mills. One example is the use of open-access databases like FAERS or NHANES, combined with analyses that rely on biased or incorrect methodologies.
Exclusive: Journal bans drug safety database papers as they flood the literature
celafon/iStockPhoto Starting around 2023, a curious trend took hold in papers on drug safety monitoring. The number of articles published on an individual drug and its link to specific adverse even…
retractionwatch.com
September 16, 2025 at 9:36 PM
This is another wake-up call about what is happening with scientific literature, which is being flooded by template papers produced by paper mills. One example is the use of open-access databases like FAERS or NHANES, combined with analyses that rely on biased or incorrect methodologies.
What could be more cheerful than Arvo Pärt dancing on the morning of his 90th birthday? His birthday concert in Riga was also absolutely stunning. www.reddit.com/r/classicalm...
From the classicalmusic community on Reddit: Arvo Part Turns 90
Explore this post and more from the classicalmusic community
www.reddit.com
September 13, 2025 at 10:32 AM
What could be more cheerful than Arvo Pärt dancing on the morning of his 90th birthday? His birthday concert in Riga was also absolutely stunning. www.reddit.com/r/classicalm...
Reposted by Signe Mežinska
The Russians are showing the same disregard for marine wildlife as they do for human life, by dispatching an increasing number of non-ice class ships to sail on the Northern Sea Route. To prevent an environmental disaster, the Russian shadow fleet must be blocked.
A 20-year-old 'shadow fleet' oil tanker without ice-class is entering icy Arctic route
The Mires is 244 meter long and sails under the flag of Sierra Leone. “Ships of this kind are in danger of serious damage if they get in contact with sea ice,” says a professor in ice navigation.
www.thebarentsobserver.com
September 13, 2025 at 5:52 AM
The Russians are showing the same disregard for marine wildlife as they do for human life, by dispatching an increasing number of non-ice class ships to sail on the Northern Sea Route. To prevent an environmental disaster, the Russian shadow fleet must be blocked.
Reposted by Signe Mežinska
INSPECT-SR has launched today — a new tool for researchers to detect problematic randomized controlled trials.
🔗 Find out more here: www.cochrane.org/about-us/new...
#INSPECTSR #ClinicalTrials #EvidenceBasedMedicine #SystematicReviews #ResearchIntegrity
🔗 Find out more here: www.cochrane.org/about-us/new...
#INSPECTSR #ClinicalTrials #EvidenceBasedMedicine #SystematicReviews #ResearchIntegrity
September 8, 2025 at 1:49 PM
INSPECT-SR has launched today — a new tool for researchers to detect problematic randomized controlled trials.
🔗 Find out more here: www.cochrane.org/about-us/new...
#INSPECTSR #ClinicalTrials #EvidenceBasedMedicine #SystematicReviews #ResearchIntegrity
🔗 Find out more here: www.cochrane.org/about-us/new...
#INSPECTSR #ClinicalTrials #EvidenceBasedMedicine #SystematicReviews #ResearchIntegrity
Here we are: "This non-profit grassroots site identifies and verifies courses where ALL student work is done in person, offline, and on paper. " certifiedaifreeskillsandknowledge.org
Certified AI-Free Skills and Knowledge
The place to go to know whether they really know
certifiedaifreeskillsandknowledge.org
September 6, 2025 at 8:24 AM
Here we are: "This non-profit grassroots site identifies and verifies courses where ALL student work is done in person, offline, and on paper. " certifiedaifreeskillsandknowledge.org
Sunday mood. Great to be part of a gatherer nation.
August 24, 2025 at 2:45 PM
Sunday mood. Great to be part of a gatherer nation.
Reposted by Signe Mežinska
🌟 Want to become a #ResearchIntegrity trainer?
The next VIRT2UE Train-the-Trainers course still has a few spots open!
🧭 Learn to guide others in responsible research
📄 Flyer below
🔗 Register here 👉 www.xendens.nl/p/31/dienste...
The next VIRT2UE Train-the-Trainers course still has a few spots open!
🧭 Learn to guide others in responsible research
📄 Flyer below
🔗 Register here 👉 www.xendens.nl/p/31/dienste...
August 22, 2025 at 8:45 AM
🌟 Want to become a #ResearchIntegrity trainer?
The next VIRT2UE Train-the-Trainers course still has a few spots open!
🧭 Learn to guide others in responsible research
📄 Flyer below
🔗 Register here 👉 www.xendens.nl/p/31/dienste...
The next VIRT2UE Train-the-Trainers course still has a few spots open!
🧭 Learn to guide others in responsible research
📄 Flyer below
🔗 Register here 👉 www.xendens.nl/p/31/dienste...