@sfb1454.bsky.social
News from SFB1454 Metaflammation and Cellular Programming
www.sfb1454-metaflammation.de
www.sfb1454-metaflammation.de
🚀 Angelika Rambold presented her exciting research in our #SFB1454 seminar series mapping organelles dynamics during immune cell activation. Fascinating insights into cell dynamics! 🔬🧫 #CellBiology #Immunology #OrganelleDynamics
September 11, 2025 at 2:20 PM
🚀 Angelika Rambold presented her exciting research in our #SFB1454 seminar series mapping organelles dynamics during immune cell activation. Fascinating insights into cell dynamics! 🔬🧫 #CellBiology #Immunology #OrganelleDynamics
Great teamwork by the @wachtenlab.bsky.social tenlab.bsky.social @masslab.bsky.social in our #SFB1454! Congratulations to the whole team!
🚨 New in The EMBO Journal!
Loss of BBS8 disrupts ciliary Hedgehog signaling, switching adipocyte precursors into fibrogenic cells—remodeling adipose tissue before obesity begins.
🔬 #BBS #cilia @for5547.bsky.social @sfb1454.bsky.social @batenergy.bsky.social
📄 www.embopress.org/doi/full/10....
Loss of BBS8 disrupts ciliary Hedgehog signaling, switching adipocyte precursors into fibrogenic cells—remodeling adipose tissue before obesity begins.
🔬 #BBS #cilia @for5547.bsky.social @sfb1454.bsky.social @batenergy.bsky.social
📄 www.embopress.org/doi/full/10....
BBS8-dependent ciliary Hedgehog signaling governs cell fate in the white adipose tissue | The EMBO Journal
imageimageDisruption of ciliogenesis in Bardet-Biedl syndrome (BBS) leads to obesity and disrupted
adipogenesis. This study reveals that ciliary dysfunction in a mouse model of BBS
induces a a cell fa...
www.embopress.org
August 21, 2025 at 10:09 AM
Great teamwork by the @wachtenlab.bsky.social tenlab.bsky.social @masslab.bsky.social in our #SFB1454! Congratulations to the whole team!
Reposted
💡 Paper alert! We developed DEL-VPR, a potent blue-light photoswitch inducing gene expression in mammalian cells.
From basic research to antibody production, this tool offers precise & strong gene control. Teamwork with #Ningaloo
academic.oup.com/nar/article/...
#SyntheticBiology #Optogenetics
From basic research to antibody production, this tool offers precise & strong gene control. Teamwork with #Ningaloo
academic.oup.com/nar/article/...
#SyntheticBiology #Optogenetics
Potent optogenetic regulation of gene expression in mammalian cells for bioproduction and basic research
Abstract. Precise temporal and spatial control of gene expression greatly benefits the study of specific cellular circuits and activities. Compared to chem
academic.oup.com
June 30, 2025 at 4:54 PM
💡 Paper alert! We developed DEL-VPR, a potent blue-light photoswitch inducing gene expression in mammalian cells.
From basic research to antibody production, this tool offers precise & strong gene control. Teamwork with #Ningaloo
academic.oup.com/nar/article/...
#SyntheticBiology #Optogenetics
From basic research to antibody production, this tool offers precise & strong gene control. Teamwork with #Ningaloo
academic.oup.com/nar/article/...
#SyntheticBiology #Optogenetics
Interested in the "fifty shades of fat" - have a look at the german article in Spiegel online with contribution from our SFB @wachtenlab.bsky.social together with @batenergy.bsky.social www.spiegel.de/fitness/fitn...
(S+) Fitness: Fifty Shades of Fett – und nicht alle sind böse
Ganz wegtrainieren lässt es sich nie. Es kann gefährlich sein, aber auch sehr vorteilhaft: Fett ist fast überall in unserem Körper und kennt drei Farbtöne. Zehn Dinge, die Sie darüber bestimmt noch ni...
www.spiegel.de
June 25, 2025 at 3:01 PM
Interested in the "fifty shades of fat" - have a look at the german article in Spiegel online with contribution from our SFB @wachtenlab.bsky.social together with @batenergy.bsky.social www.spiegel.de/fitness/fitn...
Exciting new story in @nature.com by the @masslab.bsky.social together with SFB1454 PIs @wachtenlab.bsky.social @meissner-lab.bsky.social and others: Children born to obese mothers are at higher risk of metabolic disease—even with a healthy diet #macrophages
We are SO EXCITED to share our story @nature.com:
🧵1/
Maternal obesity reprograms fetal liver macrophages, triggering adult fatty liver disease in the offspring.
This study uncovers how Kupffer cells act as intergenerational messengers in metabolic disease.
👉 Read here: rdcu.be/erD3b
🧵1/
Maternal obesity reprograms fetal liver macrophages, triggering adult fatty liver disease in the offspring.
This study uncovers how Kupffer cells act as intergenerational messengers in metabolic disease.
👉 Read here: rdcu.be/erD3b
Kupffer cell programming by maternal obesity triggers fatty liver disease
Nature - In a mouse model, maternal obesity during pregnancy can lead to fatty liver disease in the offspring, driven by aberrant developmental programming of Kuppfer cells.
rdcu.be
June 19, 2025 at 5:16 AM
Exciting new story in @nature.com by the @masslab.bsky.social together with SFB1454 PIs @wachtenlab.bsky.social @meissner-lab.bsky.social and others: Children born to obese mothers are at higher risk of metabolic disease—even with a healthy diet #macrophages
Reposted
🥼 We’re looking for a #MSc student to work in our lab as part of their MSc thesis or internship on an interdisciplinary project @dzne.science, in Germany!
🧠 If you’re interested in #neuroinflammation and innate immune signalling in #alzheimersdisease, check out our ad👇
jobs.dzne.de/en/jobs/1014...
🧠 If you’re interested in #neuroinflammation and innate immune signalling in #alzheimersdisease, check out our ad👇
jobs.dzne.de/en/jobs/1014...
Master student (f/m/x) in the field of Neuroimmunology 1447/2025/6
jobs.dzne.de
June 2, 2025 at 5:17 AM
🥼 We’re looking for a #MSc student to work in our lab as part of their MSc thesis or internship on an interdisciplinary project @dzne.science, in Germany!
🧠 If you’re interested in #neuroinflammation and innate immune signalling in #alzheimersdisease, check out our ad👇
jobs.dzne.de/en/jobs/1014...
🧠 If you’re interested in #neuroinflammation and innate immune signalling in #alzheimersdisease, check out our ad👇
jobs.dzne.de/en/jobs/1014...
Reposted
Special issue Immunometabolism and Beyond: from Liver to Brain!
European Journal of Immunology
Article types: reviews and research articles
Submission deadline 1 November 2025
Thanks to Nadja, Matteo and Bin for this wonderful opportunity!
#immunometabolism #EJI #CRC1292 #CRC355 #CRC156 #FZI
European Journal of Immunology
Article types: reviews and research articles
Submission deadline 1 November 2025
Thanks to Nadja, Matteo and Bin for this wonderful opportunity!
#immunometabolism #EJI #CRC1292 #CRC355 #CRC156 #FZI
May 26, 2025 at 11:39 AM
Great to see research from our SFB featured at the Bardet-Biedl Syndrome Patient Days 2024! Fantastic discussions and engagement! #BBS #cilia #metaflammation
Fantastic discussions and interactions at the Bardet-Biedl Syndrome Patient Days 2024 — huge thanks to Helen for organizing such a meaningful event! #cilia #BBS @wachtenlab.bsky.social
May 25, 2025 at 2:13 PM
Great to see research from our SFB featured at the Bardet-Biedl Syndrome Patient Days 2024! Fantastic discussions and engagement! #BBS #cilia #metaflammation
👏 Huge congratulations to the @immunosens.bsky.social team!
Incredible news that @dfg.de will fund ImmunoSensation3 focusing on Immune Diversity.
Here’s to 7 more years of groundbreaking #immunology in #Bonn! 🧬🎉
#ImmunoSensation3 #ScienceFunding #Celebrate
Incredible news that @dfg.de will fund ImmunoSensation3 focusing on Immune Diversity.
Here’s to 7 more years of groundbreaking #immunology in #Bonn! 🧬🎉
#ImmunoSensation3 #ScienceFunding #Celebrate
Hurray! ImmunoSensation will go on! 🥳
The @dfg.de just announced that ImmunoSensation3, focussing on Immune Diversity will be funded!
Let us #celebrate 7 more years of #immunology in #Bonn 🎉
www.immunosensation.de/news/immunos...
The @dfg.de just announced that ImmunoSensation3, focussing on Immune Diversity will be funded!
Let us #celebrate 7 more years of #immunology in #Bonn 🎉
www.immunosensation.de/news/immunos...
Excellence Strategy Funds Bonn Cluster for Immune Research
The Bonn Cluster of Excellence ImmunoSensation will be funded for a further seven years as part of the Excellence Strategy of the German federal and state…
www.immunosensation.de
May 23, 2025 at 8:45 AM
👏 Huge congratulations to the @immunosens.bsky.social team!
Incredible news that @dfg.de will fund ImmunoSensation3 focusing on Immune Diversity.
Here’s to 7 more years of groundbreaking #immunology in #Bonn! 🧬🎉
#ImmunoSensation3 #ScienceFunding #Celebrate
Incredible news that @dfg.de will fund ImmunoSensation3 focusing on Immune Diversity.
Here’s to 7 more years of groundbreaking #immunology in #Bonn! 🧬🎉
#ImmunoSensation3 #ScienceFunding #Celebrate
Great to see PIs from @sfb1454.bsky.social contributing to Immunometabolism & beyond – from liver to brain!
A fantastic event full of inspiring talks and discussions. We're really happy to be part of it! 🙌 Thanks a lot for having us!
#immunometabolism #DFG
A fantastic event full of inspiring talks and discussions. We're really happy to be part of it! 🙌 Thanks a lot for having us!
#immunometabolism #DFG
Immunometabolism & beyond - from liver to brain.
A great success! Tx to all the speakers and participants for fantastic talks and good discussions! #immunometabolism #DFG #Universitätsmedizin Mainz
A great success! Tx to all the speakers and participants for fantastic talks and good discussions! #immunometabolism #DFG #Universitätsmedizin Mainz
May 22, 2025 at 12:21 PM
Great to see PIs from @sfb1454.bsky.social contributing to Immunometabolism & beyond – from liver to brain!
A fantastic event full of inspiring talks and discussions. We're really happy to be part of it! 🙌 Thanks a lot for having us!
#immunometabolism #DFG
A fantastic event full of inspiring talks and discussions. We're really happy to be part of it! 🙌 Thanks a lot for having us!
#immunometabolism #DFG
Reposted
Visit us at the Day of Immunology 2025!
This Saturday, April 26, you can see us at our tent at the Marktplatz in #Bonn and listen to the interesting talks at the Poststraße 26.
Visit our website for more information: www.immunosensation.de/events/day-o...
#dayofimmunology #science #immunology
This Saturday, April 26, you can see us at our tent at the Marktplatz in #Bonn and listen to the interesting talks at the Poststraße 26.
Visit our website for more information: www.immunosensation.de/events/day-o...
#dayofimmunology #science #immunology
April 25, 2025 at 5:46 AM
Visit us at the Day of Immunology 2025!
This Saturday, April 26, you can see us at our tent at the Marktplatz in #Bonn and listen to the interesting talks at the Poststraße 26.
Visit our website for more information: www.immunosensation.de/events/day-o...
#dayofimmunology #science #immunology
This Saturday, April 26, you can see us at our tent at the Marktplatz in #Bonn and listen to the interesting talks at the Poststraße 26.
Visit our website for more information: www.immunosensation.de/events/day-o...
#dayofimmunology #science #immunology
Reposted
🌍 We celebrate the international Day of Immunology!
Join us April 26 at the Marktplatz and P26 in #Bonn and check out our oversized organ models, discuss immunological topics with scientists, and perform interesting experiments.
#dayofimmunology #science #immunology #event
Join us April 26 at the Marktplatz and P26 in #Bonn and check out our oversized organ models, discuss immunological topics with scientists, and perform interesting experiments.
#dayofimmunology #science #immunology #event
April 16, 2025 at 8:46 AM
🌍 We celebrate the international Day of Immunology!
Join us April 26 at the Marktplatz and P26 in #Bonn and check out our oversized organ models, discuss immunological topics with scientists, and perform interesting experiments.
#dayofimmunology #science #immunology #event
Join us April 26 at the Marktplatz and P26 in #Bonn and check out our oversized organ models, discuss immunological topics with scientists, and perform interesting experiments.
#dayofimmunology #science #immunology #event
🚀 Exciting #SciComm in action! @masslab.bsky.social explores how our diet—especially micro- & nanoplastics—impacts the immune system 🦠🛡️ #Macrophages. A fantastic addition to our #Healthybition "what the health exhibition" at Museum Koenig, Bonn! Join us in bridging science & public awareness. 🔬✨
April 3, 2025 at 3:34 PM
🚀 Exciting #SciComm in action! @masslab.bsky.social explores how our diet—especially micro- & nanoplastics—impacts the immune system 🦠🛡️ #Macrophages. A fantastic addition to our #Healthybition "what the health exhibition" at Museum Koenig, Bonn! Join us in bridging science & public awareness. 🔬✨
Reposted
Applications are open for the 4th International School on Advanced Immunology!
Full board accommodation is covered by ImmunoSensation, with potential travel subsidies available (please note we do not cover full travel costs).
More information can be found under: www.advanced-immunology.net
Full board accommodation is covered by ImmunoSensation, with potential travel subsidies available (please note we do not cover full travel costs).
More information can be found under: www.advanced-immunology.net
March 27, 2025 at 10:09 AM
Applications are open for the 4th International School on Advanced Immunology!
Full board accommodation is covered by ImmunoSensation, with potential travel subsidies available (please note we do not cover full travel costs).
More information can be found under: www.advanced-immunology.net
Full board accommodation is covered by ImmunoSensation, with potential travel subsidies available (please note we do not cover full travel costs).
More information can be found under: www.advanced-immunology.net
New collaborative effort from our #metaflammation SFB1454 PIs headed by @masslab.bsky.social
1/ 🚨 New preprint alert! 🚨
Micro- and nanoplastics (MNPs) are everywhere, but what happens when they get inside us? Our latest study reveals how chronic plastic exposure affects macrophages and metabolism in a size-dependent manner. 🧵👇 www.researchsquare.com/article/rs-6...
Micro- and nanoplastics (MNPs) are everywhere, but what happens when they get inside us? Our latest study reveals how chronic plastic exposure affects macrophages and metabolism in a size-dependent manner. 🧵👇 www.researchsquare.com/article/rs-6...
Size-dependent plastic exposure disrupts macrophage function and tissue-specific metabolism
Plastic pollution is an emerging yet understudied environmental risk to the immune system. Once ingested, nano- and microplastic particles (MNPs) can translocate from the gut to internal organs, with ...
www.researchsquare.com
March 19, 2025 at 7:57 AM
New collaborative effort from our #metaflammation SFB1454 PIs headed by @masslab.bsky.social
Check out this great collaboration project from our #metaflammation SFB members!
We are thrilled to present our new story on #neonatal #liver #macrophages and how they crosstalk with #hepatocytes during this early stage of life
👇
👇
Kupffer cells control neonatal hepatic metabolism via Igf1 signaling https://www.biorxiv.org/content/10.1101/2025.02.19.638983v1
March 12, 2025 at 10:24 AM
Check out this great collaboration project from our #metaflammation SFB members!
*Job Opportunity*
Prof. Sven Burgdorf is seeking a Postdoc in Cellular Immunology and Metabolism as part of our SFB!
If you are passionate about #CellularImmunology and #Metaflammation find out more here:
www.uni-bonn.de/de/universit...
Prof. Sven Burgdorf is seeking a Postdoc in Cellular Immunology and Metabolism as part of our SFB!
If you are passionate about #CellularImmunology and #Metaflammation find out more here:
www.uni-bonn.de/de/universit...
Postdoc in cellular immunology and metabolism
Full time, temporary, EG 13, Reference number: 3.3/2025/13
www.uni-bonn.de
March 10, 2025 at 1:20 PM
*Job Opportunity*
Prof. Sven Burgdorf is seeking a Postdoc in Cellular Immunology and Metabolism as part of our SFB!
If you are passionate about #CellularImmunology and #Metaflammation find out more here:
www.uni-bonn.de/de/universit...
Prof. Sven Burgdorf is seeking a Postdoc in Cellular Immunology and Metabolism as part of our SFB!
If you are passionate about #CellularImmunology and #Metaflammation find out more here:
www.uni-bonn.de/de/universit...
*Job Opportunity*
Prof. Dominic Lemken is seeking a PhD candidate to research Consumer Behavior and Food Choices as part of our SFB!
If you are passionate about #ConsumerBehavior and #FoodEconomics find out more here:
www.uni-bonn.de/de/universit...
Prof. Dominic Lemken is seeking a PhD candidate to research Consumer Behavior and Food Choices as part of our SFB!
If you are passionate about #ConsumerBehavior and #FoodEconomics find out more here:
www.uni-bonn.de/de/universit...
www.uni-bonn.de
February 12, 2025 at 2:30 PM
*Job Opportunity*
Prof. Dominic Lemken is seeking a PhD candidate to research Consumer Behavior and Food Choices as part of our SFB!
If you are passionate about #ConsumerBehavior and #FoodEconomics find out more here:
www.uni-bonn.de/de/universit...
Prof. Dominic Lemken is seeking a PhD candidate to research Consumer Behavior and Food Choices as part of our SFB!
If you are passionate about #ConsumerBehavior and #FoodEconomics find out more here:
www.uni-bonn.de/de/universit...
Congratulations to the whole team! Exciting new data from the #SFB1454 - a must read for those interested in #metabolism in #microglia!
I am thrilled to share our latest article that has been published in @cp-immunity.bsky.social. We describe a new role for NLRP3 outside of its #inflammasome complex, where it can regulate microglial #metabolism & key metabolites that affect the epigenetic landscape(1)
www.cell.com/immunity/ful...
www.cell.com/immunity/ful...
NLRP3-mediated glutaminolysis controls microglial phagocytosis to promote Alzheimer’s disease progression
How NLRP3 impacts Alzheimer’s disease (AD) is unclear. McManus et al. find that NLRP3
is located at mitochondria where it regulates microglial metabolism. Depletion or
chronic pharmacological inhibiti...
www.cell.com
February 4, 2025 at 6:29 AM
Congratulations to the whole team! Exciting new data from the #SFB1454 - a must read for those interested in #metabolism in #microglia!
Kicking off the 2nd funding period of our SFB1454 on #metaflammation ! Lots of great discussions and visiting our #healthybition at the #museumkoenig in Bonn! Go and visit the exhibition until end of October 2025!
January 30, 2025 at 8:27 PM
Kicking off the 2nd funding period of our SFB1454 on #metaflammation ! Lots of great discussions and visiting our #healthybition at the #museumkoenig in Bonn! Go and visit the exhibition until end of October 2025!
Reposted
Decoding cilia signaling and function by the one and only @wachtenlab.bsky.social Thanks for delivering a fantastic #FEBS national lecture at the Norwegian bioscience society winter meeting.
January 25, 2025 at 3:24 PM
Decoding cilia signaling and function by the one and only @wachtenlab.bsky.social Thanks for delivering a fantastic #FEBS national lecture at the Norwegian bioscience society winter meeting.
Great conference organized by our colleagues - register if you are interested in #brownfat function and metabolism! Looking forward seeing you in Bonn!
We would like to welcome you to our second International Conference on Brown and Beige Fat
March 31st - April 02nd 2025
Top-class speakers, cutting edge research and respected experts will come together in beautiful Bonn.
Registration is open!
www.trr333.uni-bonn.de/batenergy-sy...
January 22, 2025 at 4:12 PM
Great conference organized by our colleagues - register if you are interested in #brownfat function and metabolism! Looking forward seeing you in Bonn!
Reposted
🚨 Job alert 🚨
1 PhD + 1 Technician
Our lab is looking for motivated candidates interested in understanding the impact of diets and lifestyle on tumor development, anti-tumor immunity and metastasis! Apply and join our team!
Info below 👇
1 PhD + 1 Technician
Our lab is looking for motivated candidates interested in understanding the impact of diets and lifestyle on tumor development, anti-tumor immunity and metastasis! Apply and join our team!
Info below 👇
January 14, 2025 at 7:28 PM
🚨 Job alert 🚨
1 PhD + 1 Technician
Our lab is looking for motivated candidates interested in understanding the impact of diets and lifestyle on tumor development, anti-tumor immunity and metastasis! Apply and join our team!
Info below 👇
1 PhD + 1 Technician
Our lab is looking for motivated candidates interested in understanding the impact of diets and lifestyle on tumor development, anti-tumor immunity and metastasis! Apply and join our team!
Info below 👇
Reposted
🚨 Open #position! The group of Christoph Wilhelm at the University Hospital Bonn is looking for a
Postdoctoral fellow (m/f/d) – metabolic and nutritional regulation of immunity
Application deadline is February 10!
Visit our website for more information.
#job #postdoc #science #immunology
Postdoctoral fellow (m/f/d) – metabolic and nutritional regulation of immunity
Application deadline is February 10!
Visit our website for more information.
#job #postdoc #science #immunology
January 15, 2025 at 6:54 AM
🚨 Open #position! The group of Christoph Wilhelm at the University Hospital Bonn is looking for a
Postdoctoral fellow (m/f/d) – metabolic and nutritional regulation of immunity
Application deadline is February 10!
Visit our website for more information.
#job #postdoc #science #immunology
Postdoctoral fellow (m/f/d) – metabolic and nutritional regulation of immunity
Application deadline is February 10!
Visit our website for more information.
#job #postdoc #science #immunology
Reposted
The EMBO Lab Sustainability Award recognizes pioneers of environmental #sustainability in #lifescience research. Individuals representing a group initiative can apply from now until 14 March 2025. www.embo.org/the-embo-com...
EMBO Lab Sustainability Award – The EMBO communities – EMBO
Recognizing pioneers of environmental sustainability in life science research
www.embo.org
January 15, 2025 at 2:38 PM
The EMBO Lab Sustainability Award recognizes pioneers of environmental #sustainability in #lifescience research. Individuals representing a group initiative can apply from now until 14 March 2025. www.embo.org/the-embo-com...