Charles Vaske
@seavaske.com
Genomics, bioinformatics, diagnostics, cancer, housing, and transit. Слава Україні https://orcid.org/0000-0001-8151-6612
Reposted by Charles Vaske
Science takes a village. Thanks to everyone who has mentored a scientist, and all those awesome mentees.
Our TUBI program has been exposing students to childhood cancer research for seven years. Thanks to gifts from Dragon Master Initiative and @ucscscience.bsky.social Degree Defining Experiences, 80 new undergrads joining the network, becoming scientists and advocates 👏🏽👏🏿👏 news.ucsc.edu/2026/02/expa...
February 5, 2026 at 6:02 PM
Science takes a village. Thanks to everyone who has mentored a scientist, and all those awesome mentees.
Reposted by Charles Vaske
Suburban observers say ICE has only been more aggressive since Homan: “I think they’re getting angry that we’re winning and the country is rallying around us. We’re so organized and we act with such integrity. They don’t want to admit they feel threatened by us.”
share.google/ei9giIFLsuEJ...
share.google/ei9giIFLsuEJ...
Pursued by federal agents, suburban ICE observers remain resolved
After a frightening pursuit by federal agents, suburban ICE observers say fear hasn’t stopped them from protecting their communities.
share.google
February 4, 2026 at 3:34 PM
Suburban observers say ICE has only been more aggressive since Homan: “I think they’re getting angry that we’re winning and the country is rallying around us. We’re so organized and we act with such integrity. They don’t want to admit they feel threatened by us.”
share.google/ei9giIFLsuEJ...
share.google/ei9giIFLsuEJ...
Reposted by Charles Vaske
Trump walks out to journalists and says that Putin promised not to strike “Kyiv or other cities” for a week.
At the same time, russia is bombing several Ukrainian cities.
An apartment building is on fire in Kyiv right now. Explosions shake Kharkiv.
At the same time, russia is bombing several Ukrainian cities.
An apartment building is on fire in Kyiv right now. Explosions shake Kharkiv.
February 3, 2026 at 12:38 AM
Trump walks out to journalists and says that Putin promised not to strike “Kyiv or other cities” for a week.
At the same time, russia is bombing several Ukrainian cities.
An apartment building is on fire in Kyiv right now. Explosions shake Kharkiv.
At the same time, russia is bombing several Ukrainian cities.
An apartment building is on fire in Kyiv right now. Explosions shake Kharkiv.
Reposted by Charles Vaske
Despite being curable, tuberculosis remains one of the world’s deadliest infectious diseases—and it’s making a comeback. Explore the factors driving the TB resurgence. Addressing TB isn’t just about treatment—it’s about recognizing the warning signs before it's too late. youtu.be/QNslmoWEdqo
Tuberculosis Resurgence A Growing Threat
YouTube video by American Society for Microbiology
youtu.be
February 2, 2026 at 11:55 PM
Despite being curable, tuberculosis remains one of the world’s deadliest infectious diseases—and it’s making a comeback. Explore the factors driving the TB resurgence. Addressing TB isn’t just about treatment—it’s about recognizing the warning signs before it's too late. youtu.be/QNslmoWEdqo
Reposted by Charles Vaske
Max has been providing consistently important reporting on the state of science and the scientific workforce under the Trump administration. It's hard to see this as anything other than a reprisal for coverage that has been factual (not flattering).
I'm at the Willard Hotel where I've been denied entry and kicked out of the Reclaiming Science event with NIH director Bhattacharya & other top agency leaders.
@jocelynkaiser.bsky.social and I registered for the event months ago yet were told capacity was full, even as they let in dozens of others.
@jocelynkaiser.bsky.social and I registered for the event months ago yet were told capacity was full, even as they let in dozens of others.
January 31, 2026 at 3:30 AM
Max has been providing consistently important reporting on the state of science and the scientific workforce under the Trump administration. It's hard to see this as anything other than a reprisal for coverage that has been factual (not flattering).
Reposted by Charles Vaske
In a new paper, we introduce Metient, a new method to reconstruct the migration history of metastatic clones, and learn cancer-type specific patterns of metastatic spread, from bulk or single-cell sequencing data.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Inferring cancer type-specific patterns of metastatic spread using Metient - Nature Methods
Metient is a statistical framework that infers patterns of metastatic spread and reconstructs cancer migration histories.
www.nature.com
January 29, 2026 at 5:46 PM
In a new paper, we introduce Metient, a new method to reconstruct the migration history of metastatic clones, and learn cancer-type specific patterns of metastatic spread, from bulk or single-cell sequencing data.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Charles Vaske
just shipped mviz 1.5 - now with mermaid support!
add it your claude code with `npx add-skill matsonj/mviz`
or
embedded it in your app with `npm i mviz`
github.com/matsonj/mviz
add it your claude code with `npx add-skill matsonj/mviz`
or
embedded it in your app with `npm i mviz`
github.com/matsonj/mviz
GitHub - matsonj/mviz: A chart & report builder designed for use by AI.
A chart & report builder designed for use by AI. Contribute to matsonj/mviz development by creating an account on GitHub.
github.com
January 29, 2026 at 2:59 AM
just shipped mviz 1.5 - now with mermaid support!
add it your claude code with `npx add-skill matsonj/mviz`
or
embedded it in your app with `npm i mviz`
github.com/matsonj/mviz
add it your claude code with `npx add-skill matsonj/mviz`
or
embedded it in your app with `npm i mviz`
github.com/matsonj/mviz
Reposted by Charles Vaske
I love this idea: duckdb.org/community_ex.... It translates dplyr syntax _inside_ of duckdb so you can mix it with regular SQL
dplyr
DuckDB Community Extensions R dplyr pipeline syntax support for DuckDB - transpiles dplyr verbs to SQL
duckdb.org
January 27, 2026 at 7:08 PM
I love this idea: duckdb.org/community_ex.... It translates dplyr syntax _inside_ of duckdb so you can mix it with regular SQL
Reposted by Charles Vaske
NEW: An audit of routinely updated CDC public databases found that 46% of these databases stopped publishing updates in 2025. The authors warn that these health data gaps could impact public health guidance and trust. Read now: https://bit.ly/4qN25j4
January 27, 2026 at 5:15 PM
NEW: An audit of routinely updated CDC public databases found that 46% of these databases stopped publishing updates in 2025. The authors warn that these health data gaps could impact public health guidance and trust. Read now: https://bit.ly/4qN25j4
Fantasy Author: I invented the palantir as a cautionary device to show that those with great power can use technology to deceive those of good will
Worker at company named Palantir: my labor is being used to enable WHAT?!
Worker at company named Palantir: my labor is being used to enable WHAT?!
Palantir employees are pressing company leadership over its work for ICE in internal company Slacks obtained by @wired.com
"In my opinion ICE are the bad guys. I am not proud that the company I enjoy so much working for is part of this."
Scoop from @makenakelly.bsky.social
"In my opinion ICE are the bad guys. I am not proud that the company I enjoy so much working for is part of this."
Scoop from @makenakelly.bsky.social
Palantir Defends Work With ICE to Staff Following Killing of Alex Pretti
“In my opinion ICE are the bad guys. I am not proud that the company I enjoy so much working for is part of this,” one worker wrote on Slack.
www.wired.com
January 26, 2026 at 11:15 PM
Fantasy Author: I invented the palantir as a cautionary device to show that those with great power can use technology to deceive those of good will
Worker at company named Palantir: my labor is being used to enable WHAT?!
Worker at company named Palantir: my labor is being used to enable WHAT?!
Reposted by Charles Vaske
"I do believe that West Europeans are shocked because they don't understand what Trump is doing, and East Europeans, we are scared because we do."--Ivan Krastev
Trump’s New World Disorder with Adam Tooze and Ivan Krastev | The Weekly Show with Jon Stewart
YouTube video by The Weekly Show with Jon Stewart
www.youtube.com
January 26, 2026 at 4:15 AM
"I do believe that West Europeans are shocked because they don't understand what Trump is doing, and East Europeans, we are scared because we do."--Ivan Krastev
Reposted by Charles Vaske
Protesters chanting "We're not cold, we're not afraid, Minne[apolis/sota] taught us to be brave" in Boston tonight outside Government Center station.
January 25, 2026 at 1:06 AM
Protesters chanting "We're not cold, we're not afraid, Minne[apolis/sota] taught us to be brave" in Boston tonight outside Government Center station.
Reposted by Charles Vaske
Reposted by Charles Vaske
Hawaii governor Josh Green takes on RFKJr over vaccines. "Green said the Trump administration has laid a foundation of distrust, and 'now you’re seeing the terrible outcomes.'"
www.westhawaiitoday.com/2026/01/22/h...
www.westhawaiitoday.com/2026/01/22/h...
Gov. Green blasts federal misinformation as measles cases surge in U.S. - West Hawaii Today
Gov. Green blasts federal misinformation as measles cases surge in U.S. – Hawaii News | West Hawaii Today
www.westhawaiitoday.com
January 24, 2026 at 2:25 AM
Hawaii governor Josh Green takes on RFKJr over vaccines. "Green said the Trump administration has laid a foundation of distrust, and 'now you’re seeing the terrible outcomes.'"
www.westhawaiitoday.com/2026/01/22/h...
www.westhawaiitoday.com/2026/01/22/h...
The US's massive clean energy manufacturing boom is being cancelled. If the US wants to catch up, US manufacturing needs to have the scale to compete on the global stage. We need more action to avert the worst climate disasters.
www.canarymedia.com/articles/cle...
www.canarymedia.com/articles/cle...
January 23, 2026 at 5:30 PM
The US's massive clean energy manufacturing boom is being cancelled. If the US wants to catch up, US manufacturing needs to have the scale to compete on the global stage. We need more action to avert the worst climate disasters.
www.canarymedia.com/articles/cle...
www.canarymedia.com/articles/cle...
Reposted by Charles Vaske
And just like that, the US has left the World Health Organization.
Link goes to the official announcement—lies pretending to justify a decision that will kill countless numbers—from people too stupid to even include a proper twittercard.
www.hhs.gov/press-room/u...
Link goes to the official announcement—lies pretending to justify a decision that will kill countless numbers—from people too stupid to even include a proper twittercard.
www.hhs.gov/press-room/u...
January 23, 2026 at 3:05 AM
And just like that, the US has left the World Health Organization.
Link goes to the official announcement—lies pretending to justify a decision that will kill countless numbers—from people too stupid to even include a proper twittercard.
www.hhs.gov/press-room/u...
Link goes to the official announcement—lies pretending to justify a decision that will kill countless numbers—from people too stupid to even include a proper twittercard.
www.hhs.gov/press-room/u...
Reposted by Charles Vaske
Who wore it better?
Cow Tools!
We have lived alongside cows for nearly 10,000 years.
We breed them and exploit them
It is now, only now, that we have discovered THEY CAN USE TOOLS
Here I describe our study
(paper) www.sciencedirect.com/science/arti... in @currentbiology.bsky.social
with @auersperga.bsky.social
We have lived alongside cows for nearly 10,000 years.
We breed them and exploit them
It is now, only now, that we have discovered THEY CAN USE TOOLS
Here I describe our study
(paper) www.sciencedirect.com/science/arti... in @currentbiology.bsky.social
with @auersperga.bsky.social
January 19, 2026 at 8:01 PM
Who wore it better?
Reposted by Charles Vaske
Back in 2022, we warned that letting Ru get away with anachronistic conquest would unleash other conquests but it did not cross my mind for one second that the US would be the potential perpetrator and its allies the potential victims!
January 18, 2026 at 5:54 PM
Back in 2022, we warned that letting Ru get away with anachronistic conquest would unleash other conquests but it did not cross my mind for one second that the US would be the potential perpetrator and its allies the potential victims!
Reposted by Charles Vaske
As far as I can tell, @billmckibben.bsky.social is the only writer with any real reach who is discussing the liberatory potential of distributed solar power. I'd like that subject to get a lot more air time.
Solar as Solidarity
It's not just for saving planets any more
billmckibben.substack.com
January 15, 2026 at 9:41 PM
As far as I can tell, @billmckibben.bsky.social is the only writer with any real reach who is discussing the liberatory potential of distributed solar power. I'd like that subject to get a lot more air time.
Reposted by Charles Vaske
Thanks to the authors for sharing all components of this beautiful mouse embryo spatial transcriptomics data from cell gene counts to per-molecule coordinates: www.ahajournals.org/doi/full/10....
So I vibe coded an app to explore the 3D subcellular transcript organization: jef.works/CellCarto-Mo...
So I vibe coded an app to explore the 3D subcellular transcript organization: jef.works/CellCarto-Mo...
January 15, 2026 at 7:45 PM
Thanks to the authors for sharing all components of this beautiful mouse embryo spatial transcriptomics data from cell gene counts to per-molecule coordinates: www.ahajournals.org/doi/full/10....
So I vibe coded an app to explore the 3D subcellular transcript organization: jef.works/CellCarto-Mo...
So I vibe coded an app to explore the 3D subcellular transcript organization: jef.works/CellCarto-Mo...
Reposted by Charles Vaske
This reminded me of an unbiasedness example. Coin has Pr(heads)=p. If your first flip is tails, stop (N=1). If your first flip is heads, flip it a million times. The only unbiased estimate of p is to use the first flip only, ignoring 1 million flips even if you have them. That feels…problematic.
January 9, 2026 at 2:36 PM
This reminded me of an unbiasedness example. Coin has Pr(heads)=p. If your first flip is tails, stop (N=1). If your first flip is heads, flip it a million times. The only unbiased estimate of p is to use the first flip only, ignoring 1 million flips even if you have them. That feels…problematic.
Reposted by Charles Vaske
Enjoyed seeing this wholesome guy just noping all of Fox's leading questions. It was like
Q:Don't you thinks she was wrong?
A: No obviously ICE was wrong
Q: What about the people who shouldn't be here?
A: Obviously they should be here
Q: Anything el--
A: I have a bell!
Q:Don't you thinks she was wrong?
A: No obviously ICE was wrong
Q: What about the people who shouldn't be here?
A: Obviously they should be here
Q: Anything el--
A: I have a bell!
Hannity has a Fox reporter in Minneapolis talk to a random protester walking through the city who goes on to spit bars for 2 minutes
January 10, 2026 at 4:06 AM
Enjoyed seeing this wholesome guy just noping all of Fox's leading questions. It was like
Q:Don't you thinks she was wrong?
A: No obviously ICE was wrong
Q: What about the people who shouldn't be here?
A: Obviously they should be here
Q: Anything el--
A: I have a bell!
Q:Don't you thinks she was wrong?
A: No obviously ICE was wrong
Q: What about the people who shouldn't be here?
A: Obviously they should be here
Q: Anything el--
A: I have a bell!
Reposted by Charles Vaske
Timberwolves hold a moment of silence for Renee Nicole Good
January 9, 2026 at 1:04 AM
Timberwolves hold a moment of silence for Renee Nicole Good
2025 is the year where "my ignorance is better than your knowledge" took over far too much of the zeitgeist. Time to reassert that reality exists, and that reality is a higher power than personal taste.
The healthiest thing for me to do right now is to fight ignorance and I'm taking the kid gloves off.
January 7, 2026 at 7:20 PM
2025 is the year where "my ignorance is better than your knowledge" took over far too much of the zeitgeist. Time to reassert that reality exists, and that reality is a higher power than personal taste.
Reposted by Charles Vaske
In 2026, we can’t take the easy path by giving in to despair. We have to keep doing something to be ready for the moment the right combination of events align and we can see a better future.
January 3, 2026 at 10:30 PM
In 2026, we can’t take the easy path by giving in to despair. We have to keep doing something to be ready for the moment the right combination of events align and we can see a better future.