Science in Seattle
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Your complete source for all the life science news and events in the Seattle area. Brought to you by the Science in the City program @stemcell.com.
Researchers in the BRAIN Initiative Cell Atlas Network have unveiled their next endeavor: comprehensive and multimodal cell-type atlases of the developing human, mouse, and non-human primate brains.
Check out the work from the @alleninstitute.org and their colleagues: https://go.nature.com/4hT3yRj
Check out the work from the @alleninstitute.org and their colleagues: https://go.nature.com/4hT3yRj
November 11, 2025 at 1:13 AM
Researchers in the BRAIN Initiative Cell Atlas Network have unveiled their next endeavor: comprehensive and multimodal cell-type atlases of the developing human, mouse, and non-human primate brains.
Check out the work from the @alleninstitute.org and their colleagues: https://go.nature.com/4hT3yRj
Check out the work from the @alleninstitute.org and their colleagues: https://go.nature.com/4hT3yRj
Reposted by Science in Seattle
Join us for a special @varianteffect.bsky.social Fireside Chat on Jan 6th, 2026 (9-10am Pacific) w/ @maitreya.bsky.social (@uwgenome.bsky.social) & @mehurles.bsky.social (@sangerinstitute.bsky.social)
Visit www.varianteffect.org/event/firesi...
for more info and to add this event to your calendar
Visit www.varianteffect.org/event/firesi...
for more info and to add this event to your calendar
November 10, 2025 at 2:30 PM
Join us for a special @varianteffect.bsky.social Fireside Chat on Jan 6th, 2026 (9-10am Pacific) w/ @maitreya.bsky.social (@uwgenome.bsky.social) & @mehurles.bsky.social (@sangerinstitute.bsky.social)
Visit www.varianteffect.org/event/firesi...
for more info and to add this event to your calendar
Visit www.varianteffect.org/event/firesi...
for more info and to add this event to your calendar
Von Willebrand factor (VWF) is key for clotting post-injury, but can have devastating effects when it causes thrombosis.
Dr. Gianluca Interlandi at @uwmedicine.bsky.social identified a ligand that binds to oxidized VWF molecules, preventing excessive clotting: https://bit.ly/47P8Usb
Dr. Gianluca Interlandi at @uwmedicine.bsky.social identified a ligand that binds to oxidized VWF molecules, preventing excessive clotting: https://bit.ly/47P8Usb
November 7, 2025 at 2:40 AM
Von Willebrand factor (VWF) is key for clotting post-injury, but can have devastating effects when it causes thrombosis.
Dr. Gianluca Interlandi at @uwmedicine.bsky.social identified a ligand that binds to oxidized VWF molecules, preventing excessive clotting: https://bit.ly/47P8Usb
Dr. Gianluca Interlandi at @uwmedicine.bsky.social identified a ligand that binds to oxidized VWF molecules, preventing excessive clotting: https://bit.ly/47P8Usb
🏆 The Washington Research Foundation has awarded a $5.2 million grant to @fredhutch.org and @seattlechildrens.org scientists to develop a program that enables clinical trials of innovative therapeutics.
Congratulations to Drs. Folashade Otegbeye and Mignon Loh: https://bit.ly/47F5yro
Congratulations to Drs. Folashade Otegbeye and Mignon Loh: https://bit.ly/47F5yro
November 5, 2025 at 11:09 PM
🏆 The Washington Research Foundation has awarded a $5.2 million grant to @fredhutch.org and @seattlechildrens.org scientists to develop a program that enables clinical trials of innovative therapeutics.
Congratulations to Drs. Folashade Otegbeye and Mignon Loh: https://bit.ly/47F5yro
Congratulations to Drs. Folashade Otegbeye and Mignon Loh: https://bit.ly/47F5yro
In the largest study of its kind, published in Nature, @alleninstitute.org scientists discovered that our #TCells undergo profound and specific changes as we age.
These changes are a fundamental feature of healthy aging and will happen to all of us as we get older: https://bit.ly/47E2L1X
These changes are a fundamental feature of healthy aging and will happen to all of us as we get older: https://bit.ly/47E2L1X
November 5, 2025 at 12:32 AM
In the largest study of its kind, published in Nature, @alleninstitute.org scientists discovered that our #TCells undergo profound and specific changes as we age.
These changes are a fundamental feature of healthy aging and will happen to all of us as we get older: https://bit.ly/47E2L1X
These changes are a fundamental feature of healthy aging and will happen to all of us as we get older: https://bit.ly/47E2L1X
The @alleninstitute.org announced the appointment of Dr. Susan Kaech as Executive Vice President for its Immunology moonshot: a major research initiative focused on decoding the immune system as the foundation for human health and disease.
Learn more about the project: https://bit.ly/43SKOLN
Learn more about the project: https://bit.ly/43SKOLN
November 4, 2025 at 2:00 AM
The @alleninstitute.org announced the appointment of Dr. Susan Kaech as Executive Vice President for its Immunology moonshot: a major research initiative focused on decoding the immune system as the foundation for human health and disease.
Learn more about the project: https://bit.ly/43SKOLN
Learn more about the project: https://bit.ly/43SKOLN
Reposted by Science in Seattle
When creativity is a value, you know the Halloween costumes will never disappoint #AtAllenInstitute!
Check out all of the fabulous costumes on our Flickr: https://flickr.com/photos/allen_institute/albums/72177720330002316/
#HappyHalloween
Check out all of the fabulous costumes on our Flickr: https://flickr.com/photos/allen_institute/albums/72177720330002316/
#HappyHalloween
October 31, 2025 at 7:51 PM
When creativity is a value, you know the Halloween costumes will never disappoint #AtAllenInstitute!
Check out all of the fabulous costumes on our Flickr: https://flickr.com/photos/allen_institute/albums/72177720330002316/
#HappyHalloween
Check out all of the fabulous costumes on our Flickr: https://flickr.com/photos/allen_institute/albums/72177720330002316/
#HappyHalloween
👻 Happy Halloween!
Whether you’re brewing potions, sequencing spooky genomes, or just enjoying some candy corn, we hope your day is full of fun, fright, and a little scientific curiosity. 🧪
Whether you’re brewing potions, sequencing spooky genomes, or just enjoying some candy corn, we hope your day is full of fun, fright, and a little scientific curiosity. 🧪
October 31, 2025 at 6:02 PM
👻 Happy Halloween!
Whether you’re brewing potions, sequencing spooky genomes, or just enjoying some candy corn, we hope your day is full of fun, fright, and a little scientific curiosity. 🧪
Whether you’re brewing potions, sequencing spooky genomes, or just enjoying some candy corn, we hope your day is full of fun, fright, and a little scientific curiosity. 🧪
🐸 Ever wonder how frogs help solve cancer mysteries?
At @fredhutch.org , Dr. Yasuhiro Arimura is using frog-egg extracts to understand chromatin like never before, revealing structures that could unlock new insights into cancer and cell division: https://bit.ly/3Jms9kH
At @fredhutch.org , Dr. Yasuhiro Arimura is using frog-egg extracts to understand chromatin like never before, revealing structures that could unlock new insights into cancer and cell division: https://bit.ly/3Jms9kH
October 31, 2025 at 1:20 AM
🐸 Ever wonder how frogs help solve cancer mysteries?
At @fredhutch.org , Dr. Yasuhiro Arimura is using frog-egg extracts to understand chromatin like never before, revealing structures that could unlock new insights into cancer and cell division: https://bit.ly/3Jms9kH
At @fredhutch.org , Dr. Yasuhiro Arimura is using frog-egg extracts to understand chromatin like never before, revealing structures that could unlock new insights into cancer and cell division: https://bit.ly/3Jms9kH
Stay ahead of Seattle's science scene!
Subscribe to the Science in Seattle newsletter for and never miss out on:
📰 The latest research news & publications
🎟️ Upcoming science events
💼 Local job listings
Be part of the community driving science forward: https://bit.ly/47vBnTF
Subscribe to the Science in Seattle newsletter for and never miss out on:
📰 The latest research news & publications
🎟️ Upcoming science events
💼 Local job listings
Be part of the community driving science forward: https://bit.ly/47vBnTF
October 29, 2025 at 6:16 PM
Stay ahead of Seattle's science scene!
Subscribe to the Science in Seattle newsletter for and never miss out on:
📰 The latest research news & publications
🎟️ Upcoming science events
💼 Local job listings
Be part of the community driving science forward: https://bit.ly/47vBnTF
Subscribe to the Science in Seattle newsletter for and never miss out on:
📰 The latest research news & publications
🎟️ Upcoming science events
💼 Local job listings
Be part of the community driving science forward: https://bit.ly/47vBnTF
What if two #VaccineTechnologies—mRNA delivery and custom protein nanoparticles—could be combined, capturing the benefits of both?
That’s the idea behind a new study published by Grace Hendricks and the King Lab at @uwproteindesign.bsky.social : https://bit.ly/4nuPcrD
That’s the idea behind a new study published by Grace Hendricks and the King Lab at @uwproteindesign.bsky.social : https://bit.ly/4nuPcrD
October 28, 2025 at 11:46 PM
What if two #VaccineTechnologies—mRNA delivery and custom protein nanoparticles—could be combined, capturing the benefits of both?
That’s the idea behind a new study published by Grace Hendricks and the King Lab at @uwproteindesign.bsky.social : https://bit.ly/4nuPcrD
That’s the idea behind a new study published by Grace Hendricks and the King Lab at @uwproteindesign.bsky.social : https://bit.ly/4nuPcrD
📣 The International Academy of Digital Arts & Sciences has nominated the MICrONS Project, which began at @alleninstitute.org , for a prestigious Anthem Award!
The project is also nominated for a “People’s Choice” Community Voice Award. Help them win by voting before Oct. 30! https://bit.ly/47nMKNm
The project is also nominated for a “People’s Choice” Community Voice Award. Help them win by voting before Oct. 30! https://bit.ly/47nMKNm
October 28, 2025 at 1:32 AM
📣 The International Academy of Digital Arts & Sciences has nominated the MICrONS Project, which began at @alleninstitute.org , for a prestigious Anthem Award!
The project is also nominated for a “People’s Choice” Community Voice Award. Help them win by voting before Oct. 30! https://bit.ly/47nMKNm
The project is also nominated for a “People’s Choice” Community Voice Award. Help them win by voting before Oct. 30! https://bit.ly/47nMKNm
Reposted by Science in Seattle
Dr. @yarimura.bsky.social brings frogs back to Fred Hutch after a long absence to study the structure of DNA-linked molecular complexes that change during the cell cycle and malfunction in cancer and other diseases. bit.ly/3J8S5Ae
Frogs help Fred Hutch find the shape of small things
Frogs have made significant contributions to Fred Hutch science over the years as a model organism that shares much of our biology, but they've been absent from the menagerie for about two decades. Dr...
bit.ly
October 27, 2025 at 9:33 PM
Dr. @yarimura.bsky.social brings frogs back to Fred Hutch after a long absence to study the structure of DNA-linked molecular complexes that change during the cell cycle and malfunction in cancer and other diseases. bit.ly/3J8S5Ae
Dr. Karel Svoboda from the @alleninstitute.org and Dr. Jay Shendure ( @jshendure.bsky.social ) from @uwmedicine.bsky.social have been elected to the National Academy of Medicine ( @nam.edu )!
Congratulations to both researchers on this prestigious honor: https://bit.ly/3JqLBg3
Congratulations to both researchers on this prestigious honor: https://bit.ly/3JqLBg3
October 24, 2025 at 4:02 PM
Dr. Karel Svoboda from the @alleninstitute.org and Dr. Jay Shendure ( @jshendure.bsky.social ) from @uwmedicine.bsky.social have been elected to the National Academy of Medicine ( @nam.edu )!
Congratulations to both researchers on this prestigious honor: https://bit.ly/3JqLBg3
Congratulations to both researchers on this prestigious honor: https://bit.ly/3JqLBg3
We're at Cascadia 6.0!
👋 Swing by the UW SLU campus and say hi!
👋 Swing by the UW SLU campus and say hi!
October 24, 2025 at 12:00 AM
We're at Cascadia 6.0!
👋 Swing by the UW SLU campus and say hi!
👋 Swing by the UW SLU campus and say hi!
The latest episode of the Lab Notes Podcast by the @alleninstitute.org explores how cells could be turned into living DNA recorders that chronicle their complete cellular histories. 📼
👂 Listen now! https://bit.ly/3WjPpm7
#CellTherapy #SciencePodcast
👂 Listen now! https://bit.ly/3WjPpm7
#CellTherapy #SciencePodcast
October 23, 2025 at 4:06 PM
The latest episode of the Lab Notes Podcast by the @alleninstitute.org explores how cells could be turned into living DNA recorders that chronicle their complete cellular histories. 📼
👂 Listen now! https://bit.ly/3WjPpm7
#CellTherapy #SciencePodcast
👂 Listen now! https://bit.ly/3WjPpm7
#CellTherapy #SciencePodcast
🔎 New from the @jraslab.bsky.social at UW!
They used #Langerhans cells within the adult #zebrafish epidermis as a model to investigate roles of microtubules in immune cell tissue surveillance, phagocytosis, and directed migration.
🦓🐟 See it in @jcellsci.bsky.social : https://bit.ly/49fmQhf
They used #Langerhans cells within the adult #zebrafish epidermis as a model to investigate roles of microtubules in immune cell tissue surveillance, phagocytosis, and directed migration.
🦓🐟 See it in @jcellsci.bsky.social : https://bit.ly/49fmQhf
October 22, 2025 at 10:50 PM
🔎 New from the @jraslab.bsky.social at UW!
They used #Langerhans cells within the adult #zebrafish epidermis as a model to investigate roles of microtubules in immune cell tissue surveillance, phagocytosis, and directed migration.
🦓🐟 See it in @jcellsci.bsky.social : https://bit.ly/49fmQhf
They used #Langerhans cells within the adult #zebrafish epidermis as a model to investigate roles of microtubules in immune cell tissue surveillance, phagocytosis, and directed migration.
🦓🐟 See it in @jcellsci.bsky.social : https://bit.ly/49fmQhf
Reposted by Science in Seattle
Registration is now open! The Seventh Seattle Symposium in Biostatistics is online Nov 22-25 from 8:30 a.m. - 1 p.m. PST daily. Topics explore the role causal inference in biomedical research. Check out keynote speakers, daily session topics, and more: www.biostat.washington.edu/seattlesympo...
October 14, 2025 at 5:59 PM
Registration is now open! The Seventh Seattle Symposium in Biostatistics is online Nov 22-25 from 8:30 a.m. - 1 p.m. PST daily. Topics explore the role causal inference in biomedical research. Check out keynote speakers, daily session topics, and more: www.biostat.washington.edu/seattlesympo...
Dr. Heather Parsons has been awarded the Maudslien Endowed Chair in Breast Cancer Precision Oncology Research.
Dr. Parsons’ research at @fredhutch.org focuses on a type of cancer marker called circulating tumor DNA (#ctDNA) that can be detected in human blood.
🎈 Congrats! https://bit.ly/3LlEpST
Dr. Parsons’ research at @fredhutch.org focuses on a type of cancer marker called circulating tumor DNA (#ctDNA) that can be detected in human blood.
🎈 Congrats! https://bit.ly/3LlEpST
October 21, 2025 at 4:46 PM
Dr. Heather Parsons has been awarded the Maudslien Endowed Chair in Breast Cancer Precision Oncology Research.
Dr. Parsons’ research at @fredhutch.org focuses on a type of cancer marker called circulating tumor DNA (#ctDNA) that can be detected in human blood.
🎈 Congrats! https://bit.ly/3LlEpST
Dr. Parsons’ research at @fredhutch.org focuses on a type of cancer marker called circulating tumor DNA (#ctDNA) that can be detected in human blood.
🎈 Congrats! https://bit.ly/3LlEpST
Reposted by Science in Seattle
Congratulations to Karel Svoboda and @jshendure.bsky.social on their election to the National Academy of Medicine (@nam.edu)! Election to the Academy is one of the highest honors in health and medicine. #NAMmtg
More on their journeys to this achievement: alleninstitute.org/news/karel-s...
More on their journeys to this achievement: alleninstitute.org/news/karel-s...
Karel Svoboda and Jay Shendure elected to National Academy of Medicine
The honor recognizes leaders who have demonstrated outstanding achievement and made lasting contributions to the advancement of the medical sciences, health care, and public health
alleninstitute.org
October 20, 2025 at 7:15 PM
Congratulations to Karel Svoboda and @jshendure.bsky.social on their election to the National Academy of Medicine (@nam.edu)! Election to the Academy is one of the highest honors in health and medicine. #NAMmtg
More on their journeys to this achievement: alleninstitute.org/news/karel-s...
More on their journeys to this achievement: alleninstitute.org/news/karel-s...
The DeForest lab (@coledeforest.bsky.social) at @uwiscrm.bsky.social took a big step towards creating smart, targeted therapies by designing proteins with autonomous decision-making capabilities.
📰 Article: https://bit.ly/4nQBFvj
📝 Abstract @natchembio.nature.com : https://go.nature.com/4hbTbaI
📰 Article: https://bit.ly/4nQBFvj
📝 Abstract @natchembio.nature.com : https://go.nature.com/4hbTbaI
October 20, 2025 at 3:06 PM
The DeForest lab (@coledeforest.bsky.social) at @uwiscrm.bsky.social took a big step towards creating smart, targeted therapies by designing proteins with autonomous decision-making capabilities.
📰 Article: https://bit.ly/4nQBFvj
📝 Abstract @natchembio.nature.com : https://go.nature.com/4hbTbaI
📰 Article: https://bit.ly/4nQBFvj
📝 Abstract @natchembio.nature.com : https://go.nature.com/4hbTbaI
🤩 Dr. Benjamin Freedman from @uwmedicine.bsky.social is leading a new grant to establish a core center dedicated to the development of polycystic kidney disease organoids and related in-a-dish technologies.
Congratulations! https://bit.ly/3J9YWco
Congratulations! https://bit.ly/3J9YWco
October 17, 2025 at 8:55 PM
🤩 Dr. Benjamin Freedman from @uwmedicine.bsky.social is leading a new grant to establish a core center dedicated to the development of polycystic kidney disease organoids and related in-a-dish technologies.
Congratulations! https://bit.ly/3J9YWco
Congratulations! https://bit.ly/3J9YWco
Mutations that give certain cells an evolutionary advantage may help explain why men are more likely than women and smokers are more likely than nonsmokers to develop #BladderCancer, according to a study by the Risques lab at @uwmedicine.bsky.social.
Learn more: https://bit.ly/3Jd8Nye
Learn more: https://bit.ly/3Jd8Nye
October 17, 2025 at 5:04 PM
Mutations that give certain cells an evolutionary advantage may help explain why men are more likely than women and smokers are more likely than nonsmokers to develop #BladderCancer, according to a study by the Risques lab at @uwmedicine.bsky.social.
Learn more: https://bit.ly/3Jd8Nye
Learn more: https://bit.ly/3Jd8Nye
In a scientific first, researchers at the @alleninstitute.org successfully designed a new gene therapy that reversed symptoms related to SYNGAP1-related disorders (SRD) in mice.
These are a class of brain disorders that can lead to severe and debilitating symptoms: https://bit.ly/47rylAU
These are a class of brain disorders that can lead to severe and debilitating symptoms: https://bit.ly/47rylAU
October 15, 2025 at 10:47 PM
In a scientific first, researchers at the @alleninstitute.org successfully designed a new gene therapy that reversed symptoms related to SYNGAP1-related disorders (SRD) in mice.
These are a class of brain disorders that can lead to severe and debilitating symptoms: https://bit.ly/47rylAU
These are a class of brain disorders that can lead to severe and debilitating symptoms: https://bit.ly/47rylAU
Reposted by Science in Seattle
These cells could be a fresh target for treating Alzheimer's disease and memory conditions associated with PTSD
go.nature.com/4789FvR
go.nature.com/4789FvR
How emotional memories are engraved on the brain, with surprising helper cells
Astrocytes have a more active role in stabilizing memories than once thought.
go.nature.com
October 15, 2025 at 3:30 PM
These cells could be a fresh target for treating Alzheimer's disease and memory conditions associated with PTSD
go.nature.com/4789FvR
go.nature.com/4789FvR