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Science in Seattle
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Your complete source for all the life science news and events in the Seattle area. Brought to you by the Science in the City program @stemcell.com.
Harnessing the muscle of one of the world’s fastest supercomputers, researchers at the @alleninstitute.org and their collaborators have built one of the largest and most detailed biophysically realistic brain simulations of an animal ever!

🐁 See the #MouseBrain simulation: https://bit.ly/47TFf2e
November 21, 2025 at 11:33 PM
🥰 A huge thank you to everyone who came out to make new connections and share ideas at our Seattle Life Sciences Networking Night earlier this month. And a very special thank you to our two speakers for the night: Dr. Emma Kuan and Sam Nutt.

We can’t wait to see you next time!

#SeattleScience
November 21, 2025 at 1:10 AM
OTC gene variants cause ornithine transcarbamylase deficiency, a rare X-chromosome-linked disorder that affects the body’s ability to clear ammonia.

Dr. Aimée Dudley's lab at the Pacific Northwest Research Institute isolated the genetic impact of each OTC variant using yeast: https://bit.ly/4ieTwKA
November 19, 2025 at 11:30 PM
🦠 The @isbscience.org Virtual Microbiome Symposium is on December 12, 2025! This virtual symposium will dive into the influence of gut microbial metabolites on human #physiology.

This event is perfect for everyone in academia, industry, and the clinic. Register now: https://bit.ly/4oe67iw
November 18, 2025 at 9:22 PM
A new $5.2 million grant from WRF will help develop a new clinical trials program between @fredhutch.org & @seattlechildrens.org .

The program, led by Dr. Folashade “Shade” Otegbeye, will focus on first-in-human clinical studies of brand-new therapeutics for rare cancers: https://bit.ly/3X2lteO
November 18, 2025 at 1:35 AM
🔬 Curious minds unite! Come down to Seattle Public Library SW Branch for the “Sunday Science Party” this Sunday from 2-3 PM.

This free, all-ages, hands-on event will help you and your family explore questions with local UW scientists: https://bit.ly/4oA7bOs
November 14, 2025 at 8:14 PM
Dr. Paul Thomas @pgtimmune.bsky.social is working to turn the “incredible potential” of the immune system into real-life diagnostic and therapeutic applications that will improve vaccination strategies and #CancerTreatments.

Check out his work at @fredhutch.org : https://bit.ly/4p3kmr0
November 14, 2025 at 1:11 AM
🙏 A huge thank you to everyone who joined us for From Bench to Breakthrough: Seattle Life Sciences Networking Night!

Your energy and enthusiasm made the night a success, and we can’t wait to see you at the next one!

#SeattleScience
November 13, 2025 at 2:55 AM
Researchers in the BRAIN Initiative Cell Atlas Network have unveiled their next endeavor: comprehensive and multimodal cell-type atlases of the developing human, mouse, and non-human primate brains.

Check out the work from the @alleninstitute.org and their colleagues: https://go.nature.com/4hT3yRj
November 11, 2025 at 1:13 AM
Von Willebrand factor (VWF) is key for clotting post-injury, but can have devastating effects when it causes thrombosis.

Dr. Gianluca Interlandi at @uwmedicine.bsky.social identified a ligand that binds to oxidized VWF molecules, preventing excessive clotting: https://bit.ly/47P8Usb
November 7, 2025 at 2:40 AM
🏆 The Washington Research Foundation has awarded a $5.2 million grant to @fredhutch.org and @seattlechildrens.org scientists to develop a program that enables clinical trials of innovative therapeutics.

Congratulations to Drs. Folashade Otegbeye and Mignon Loh: https://bit.ly/47F5yro
November 5, 2025 at 11:09 PM
In the largest study of its kind, published in Nature, @alleninstitute.org scientists discovered that our #TCells undergo profound and specific changes as we age.

These changes are a fundamental feature of healthy aging and will happen to all of us as we get older: https://bit.ly/47E2L1X
November 5, 2025 at 12:32 AM
The @alleninstitute.org announced the appointment of Dr. Susan Kaech as Executive Vice President for its Immunology moonshot: a major research initiative focused on decoding the immune system as the foundation for human health and disease.

Learn more about the project: https://bit.ly/43SKOLN
November 4, 2025 at 2:00 AM
👻 Happy Halloween!

Whether you’re brewing potions, sequencing spooky genomes, or just enjoying some candy corn, we hope your day is full of fun, fright, and a little scientific curiosity. 🧪
October 31, 2025 at 6:02 PM
🐸 Ever wonder how frogs help solve cancer mysteries?

At @fredhutch.org , Dr. Yasuhiro Arimura is using frog-egg extracts to understand chromatin like never before, revealing structures that could unlock new insights into cancer and cell division: https://bit.ly/3Jms9kH
October 31, 2025 at 1:20 AM
Stay ahead of Seattle's science scene!

Subscribe to the Science in Seattle newsletter for and never miss out on:
📰 The latest research news & publications
🎟️ Upcoming science events
💼 Local job listings

Be part of the community driving science forward: https://bit.ly/47vBnTF
October 29, 2025 at 6:16 PM
What if two #VaccineTechnologies—mRNA delivery and custom protein nanoparticles—could be combined, capturing the benefits of both?

That’s the idea behind a new study published by Grace Hendricks and the King Lab at @uwproteindesign.bsky.social : https://bit.ly/4nuPcrD
October 28, 2025 at 11:46 PM
📣 The International Academy of Digital Arts & Sciences has nominated the MICrONS Project, which began at @alleninstitute.org , for a prestigious Anthem Award!

The project is also nominated for a “People’s Choice” Community Voice Award. Help them win by voting before Oct. 30! https://bit.ly/47nMKNm
October 28, 2025 at 1:32 AM
Dr. Karel Svoboda from the @alleninstitute.org and Dr. Jay Shendure ( @jshendure.bsky.social ) from @uwmedicine.bsky.social have been elected to the National Academy of Medicine ( @nam.edu )!

Congratulations to both researchers on this prestigious honor: https://bit.ly/3JqLBg3
October 24, 2025 at 4:02 PM
We're at Cascadia 6.0!

👋 Swing by the UW SLU campus and say hi!
October 24, 2025 at 12:00 AM
The latest episode of the Lab Notes Podcast by the @alleninstitute.org explores how cells could be turned into living DNA recorders that chronicle their complete cellular histories. 📼

👂 Listen now! https://bit.ly/3WjPpm7

#CellTherapy #SciencePodcast
October 23, 2025 at 4:06 PM
🔎 New from the @jraslab.bsky.social at UW!

They used #Langerhans cells within the adult #zebrafish epidermis as a model to investigate roles of microtubules in immune cell tissue surveillance, phagocytosis, and directed migration.

🦓🐟 See it in @jcellsci.bsky.social : https://bit.ly/49fmQhf
October 22, 2025 at 10:50 PM
Dr. Heather Parsons has been awarded the Maudslien Endowed Chair in Breast Cancer Precision Oncology Research.

Dr. Parsons’ research at @fredhutch.org focuses on a type of cancer marker called circulating tumor DNA (#ctDNA) that can be detected in human blood.

🎈 Congrats! https://bit.ly/3LlEpST
October 21, 2025 at 4:46 PM
The DeForest lab (@coledeforest.bsky.social) at @uwiscrm.bsky.social took a big step towards creating smart, targeted therapies by designing proteins with autonomous decision-making capabilities.

📰 Article: https://bit.ly/4nQBFvj
📝 Abstract @natchembio.nature.com : https://go.nature.com/4hbTbaI
October 20, 2025 at 3:06 PM
🤩 Dr. Benjamin Freedman from @uwmedicine.bsky.social is leading a new grant to establish a core center dedicated to the development of polycystic kidney disease organoids and related in-a-dish technologies.

Congratulations! https://bit.ly/3J9YWco
October 17, 2025 at 8:55 PM