Carlos Santana Molina
@santanamolina.bsky.social
Protein evolution, phylogenetics, Tree of Life
PostDoc
PostDoc
Pinned
Chimeric origins and dynamic evolution of central carbon metabolism in eukaryotes
Nature Ecology & Evolution - Analysis of the eukaryotic gene repertoires mediating central carbon metabolism identifies ancestral contributions from Alphaproteobacteria, Asgardarchaeota and...
rdcu.be
Asgardarchaea & Alphaproteobacteria: key players for the assembly eukaryotic central carbon metabolism! Our new study reveals their gene contributions to glycolysis & TCA cycle, supporting synthrophic scenarios of eukaryogenesis.
rdcu.be/eb0aK
rdcu.be/eb0aK
Reposted by Carlos Santana Molina
Reposted by Carlos Santana Molina
Glad to share our paper out today @NatureEcoEvo: “Serial innovations by Asgard archaea shaped the DNA replication machinery of the early eukaryotic ancestor”. www.nature.com/articles/s41... #microsky #archaeasky
Serial innovations by Asgard archaea shaped the DNA replication machinery of the early eukaryotic ancestor - Nature Ecology & Evolution
Phylogenetic and biochemical analyses show a diversity of components of the DNA replication machinery in different Asgard archaea that contributed to the eukaryotic DNA replication machinery.
www.nature.com
October 21, 2025 at 3:06 PM
Glad to share our paper out today @NatureEcoEvo: “Serial innovations by Asgard archaea shaped the DNA replication machinery of the early eukaryotic ancestor”. www.nature.com/articles/s41... #microsky #archaeasky
Reposted by Carlos Santana Molina
There's a PhD position now available with me in Bath, on the evolution of symbiosis. www.findaphd.com/phds/project.... The supervisory team also includes @anja1.bsky.social @phil-donoghue.bsky.social and others. NB, this is open both to UK-based students *and* to international students :)
The genomic basis of symbiotic integration at University of Bath on FindAPhD.com
PhD Project - The genomic basis of symbiotic integration at University of Bath, listed on FindAPhD.com
www.findaphd.com
October 9, 2025 at 9:39 AM
There's a PhD position now available with me in Bath, on the evolution of symbiosis. www.findaphd.com/phds/project.... The supervisory team also includes @anja1.bsky.social @phil-donoghue.bsky.social and others. NB, this is open both to UK-based students *and* to international students :)
Reposted by Carlos Santana Molina
Very nice documentary about the origins of complex life with my PhD advisor Berend Snel @binfutrecht.bsky.social!
Hoe is al het complexe leven op aarde eigenlijk ontstaan?
Wat DNA uit slootwater ons vertelt over jouw onbekende voorouders | VPRO Tegenlicht
YouTube video by VPRO Tegenlicht
youtu.be
October 9, 2025 at 8:46 AM
Very nice documentary about the origins of complex life with my PhD advisor Berend Snel @binfutrecht.bsky.social!
Reposted by Carlos Santana Molina
Huang, @tweethinking.bsky.social, Sepang et al. use phylogenetic analyses to reveal that the Njordarchaeales and Panguiarchaeales constitute the new class Njordarchaeia within Asgard archaea.
🔗 doi.org/10.1093/molbev/msaf201
#evobio #molbio #archaea
🔗 doi.org/10.1093/molbev/msaf201
#evobio #molbio #archaea
Phylogenomic Analyses Reveal that Panguiarchaeum Is a Clade of Genome-Reduced Asgard Archaea Within the Njordarchaeia
Abstract. The Asgard archaea are a diverse archaeal phylum important for our understanding of cellular evolution because they include the lineage that gave
doi.org
September 8, 2025 at 4:50 PM
Huang, @tweethinking.bsky.social, Sepang et al. use phylogenetic analyses to reveal that the Njordarchaeales and Panguiarchaeales constitute the new class Njordarchaeia within Asgard archaea.
🔗 doi.org/10.1093/molbev/msaf201
#evobio #molbio #archaea
🔗 doi.org/10.1093/molbev/msaf201
#evobio #molbio #archaea
Reposted by Carlos Santana Molina
Happy to see our work published and glad to have contributed together with @maxraas.bsky.social ! Looking forward to all the projects that will come out of this work!
Excited to share our new paper in @cellreports.bsky.social that reshapes our understanding of chromosome organization's deep evolutionary roots! Our work dives into the origins of the machinery that structures our very genomes.
🔗: doi.org/10.1016/j.ce...
#Genomics #Evolution #CellBiology #LECA
🔗: doi.org/10.1016/j.ce...
#Genomics #Evolution #CellBiology #LECA
June 23, 2025 at 11:18 AM
Happy to see our work published and glad to have contributed together with @maxraas.bsky.social ! Looking forward to all the projects that will come out of this work!
Reposted by Carlos Santana Molina
(1/14) ¿Has probado alguna vez a trazar tu árbol genealógico? Es un ejercicio interesante para entender tus raíces, a pesar de que se complica cuantas más generaciones atrás intentas llegar…
Imagínate un árbol así, pero a escala de toda la vida en la Tierra. #HiloDivulgación
Imagínate un árbol así, pero a escala de toda la vida en la Tierra. #HiloDivulgación
June 16, 2025 at 9:57 AM
(1/14) ¿Has probado alguna vez a trazar tu árbol genealógico? Es un ejercicio interesante para entender tus raíces, a pesar de que se complica cuantas más generaciones atrás intentas llegar…
Imagínate un árbol así, pero a escala de toda la vida en la Tierra. #HiloDivulgación
Imagínate un árbol así, pero a escala de toda la vida en la Tierra. #HiloDivulgación
Reposted by Carlos Santana Molina
New vacancy in my team!
PhD student position on microbial genome evolution, focusing on the evolutionary principles underlying bacterial genome architecture.
Please repost and share with talented MSc students in #evobio, bioinformatics or related :)
www.uu.nl/en/organisat...
#MEvoSky #MicroSky
PhD student position on microbial genome evolution, focusing on the evolutionary principles underlying bacterial genome architecture.
Please repost and share with talented MSc students in #evobio, bioinformatics or related :)
www.uu.nl/en/organisat...
#MEvoSky #MicroSky
May 14, 2025 at 2:07 PM
New vacancy in my team!
PhD student position on microbial genome evolution, focusing on the evolutionary principles underlying bacterial genome architecture.
Please repost and share with talented MSc students in #evobio, bioinformatics or related :)
www.uu.nl/en/organisat...
#MEvoSky #MicroSky
PhD student position on microbial genome evolution, focusing on the evolutionary principles underlying bacterial genome architecture.
Please repost and share with talented MSc students in #evobio, bioinformatics or related :)
www.uu.nl/en/organisat...
#MEvoSky #MicroSky
Reposted by Carlos Santana Molina
#ESEB2025 Exciting symposium alert: (S50) Unravelling the origin of eukaryotes. 🦑🌴 With speakers Purificación López-García and Mark Field. We are looking forward to your abstract submissions! eseb2025.com/list-of-symp... @julianvosseberg.bsky.social
March 17, 2025 at 6:09 PM
#ESEB2025 Exciting symposium alert: (S50) Unravelling the origin of eukaryotes. 🦑🌴 With speakers Purificación López-García and Mark Field. We are looking forward to your abstract submissions! eseb2025.com/list-of-symp... @julianvosseberg.bsky.social
Reposted by Carlos Santana Molina
We got to tackle three major questions in biology. So if you are interested in...
A) The nature of LECA
B) The relevance of patchy proteins for cellular models
C) The trafficking machinery present in diplonemids
have we got a paper for you!
authors.elsevier.com/a/1km493QW8S...
#protistsonsky
A) The nature of LECA
B) The relevance of patchy proteins for cellular models
C) The trafficking machinery present in diplonemids
have we got a paper for you!
authors.elsevier.com/a/1km493QW8S...
#protistsonsky
authors.elsevier.com
March 16, 2025 at 9:50 PM
We got to tackle three major questions in biology. So if you are interested in...
A) The nature of LECA
B) The relevance of patchy proteins for cellular models
C) The trafficking machinery present in diplonemids
have we got a paper for you!
authors.elsevier.com/a/1km493QW8S...
#protistsonsky
A) The nature of LECA
B) The relevance of patchy proteins for cellular models
C) The trafficking machinery present in diplonemids
have we got a paper for you!
authors.elsevier.com/a/1km493QW8S...
#protistsonsky
Reposted by Carlos Santana Molina
John Archibald also wrote an accessible summary of the work here: www.nature.com/articles/s41...
Mosaic evolution of eukaryotic carbon metabolism - Nature Ecology & Evolution
A comparative genomic investigation of metabolism across the tree of life supports the hypothesis that syntrophy — metabolic exchange between symbiotic partners — had a key role in the evolution of eu...
www.nature.com
March 6, 2025 at 4:31 PM
John Archibald also wrote an accessible summary of the work here: www.nature.com/articles/s41...
Asgardarchaea & Alphaproteobacteria: key players for the assembly eukaryotic central carbon metabolism! Our new study reveals their gene contributions to glycolysis & TCA cycle, supporting synthrophic scenarios of eukaryogenesis.
rdcu.be/eb0aK
rdcu.be/eb0aK
Chimeric origins and dynamic evolution of central carbon metabolism in eukaryotes
Nature Ecology & Evolution - Analysis of the eukaryotic gene repertoires mediating central carbon metabolism identifies ancestral contributions from Alphaproteobacteria, Asgardarchaeota and...
rdcu.be
March 3, 2025 at 1:28 PM
Asgardarchaea & Alphaproteobacteria: key players for the assembly eukaryotic central carbon metabolism! Our new study reveals their gene contributions to glycolysis & TCA cycle, supporting synthrophic scenarios of eukaryogenesis.
rdcu.be/eb0aK
rdcu.be/eb0aK