Sahin Naqvi
@sahinnaqvi.bsky.social
Studying how transcription factor dosage is utilized in development and perturbed in disease. Faculty at Boston Children’s Hospital/Harvard Medical School. naqvilab.org
Excited to share the peer-reviewed version of our paper on predicting the chromatin response to TF dosage using transfer learning
www.cell.com/cell-genomic...
www.cell.com/cell-genomic...
Transfer learning reveals sequence determinants of the quantitative response to transcription factor dosage
Naqvi et al. reveal how DNA sequence determines the chromatin response to transcription
factor (TF) dosage changes. By combining deep learning and chemical genetics, they
uncover specific sequence fea...
www.cell.com
February 27, 2025 at 8:31 PM
Excited to share the peer-reviewed version of our paper on predicting the chromatin response to TF dosage using transfer learning
www.cell.com/cell-genomic...
www.cell.com/cell-genomic...
Reposted by Sahin Naqvi
Hello Bluesky friends! I am a #newPI starting at UC Irvine in April, interested in gene regulation and functional genomics in stem cell models of development (esp neural crest). We are hiring at all levels – please reach out/spread the word! sskimlab.org
Kim Lab at UC Irvine
Visit the post for more.
sskimlab.org
January 20, 2025 at 11:08 PM
Hello Bluesky friends! I am a #newPI starting at UC Irvine in April, interested in gene regulation and functional genomics in stem cell models of development (esp neural crest). We are hiring at all levels – please reach out/spread the word! sskimlab.org
Reposted by Sahin Naqvi
Our ChromBPNet preprint out!
www.biorxiv.org/content/10.1...
Huge congrats to Anusri! This was quite a slog (for both of us) but we r very proud of this one! It is a long read but worth it IMHO. Methods r in the supp. materials. Bluetorial coming soon below 1/
www.biorxiv.org/content/10.1...
Huge congrats to Anusri! This was quite a slog (for both of us) but we r very proud of this one! It is a long read but worth it IMHO. Methods r in the supp. materials. Bluetorial coming soon below 1/
December 25, 2024 at 11:48 PM
Our ChromBPNet preprint out!
www.biorxiv.org/content/10.1...
Huge congrats to Anusri! This was quite a slog (for both of us) but we r very proud of this one! It is a long read but worth it IMHO. Methods r in the supp. materials. Bluetorial coming soon below 1/
www.biorxiv.org/content/10.1...
Huge congrats to Anusri! This was quite a slog (for both of us) but we r very proud of this one! It is a long read but worth it IMHO. Methods r in the supp. materials. Bluetorial coming soon below 1/
Reposted by Sahin Naqvi
The latest from our group, led by Megan Ostrowski and @martyyang.bsky.social, is now published in final form (www.cell.com/cell/fulltex...! Many thanks to our excellent peer reviewers for suggesting several experiments (including CAF-1 perturbation) to really improve the study =) #epigenetics
The single-molecule accessibility landscape of newly replicated mammalian chromatin
By developing a long-read sequencing method to simultaneously map replication status
and protein-DNA contacts in cells, Ostrowski, Yang, et al. show that newly replicated
chromatin is enriched for unw...
www.cell.com
November 15, 2024 at 3:35 PM
The latest from our group, led by Megan Ostrowski and @martyyang.bsky.social, is now published in final form (www.cell.com/cell/fulltex...! Many thanks to our excellent peer reviewers for suggesting several experiments (including CAF-1 perturbation) to really improve the study =) #epigenetics
Exciting update: we have a lab website! naqvilab.org
Stay tuned for formal ads for research assistant and postdoc positions, but please reach out in the mean time if interested in joining!
Thanks to the Greene lab for the excellent lab website template
Stay tuned for formal ads for research assistant and postdoc positions, but please reach out in the mean time if interested in joining!
Thanks to the Greene lab for the excellent lab website template
Naqvi Lab
Quantitative principles of gene regulation in development and disease. Quantitative principles of gene regulation in development and disease.
naqvilab.org
January 31, 2024 at 4:28 AM
Exciting update: we have a lab website! naqvilab.org
Stay tuned for formal ads for research assistant and postdoc positions, but please reach out in the mean time if interested in joining!
Thanks to the Greene lab for the excellent lab website template
Stay tuned for formal ads for research assistant and postdoc positions, but please reach out in the mean time if interested in joining!
Thanks to the Greene lab for the excellent lab website template
Reposted by Sahin Naqvi
I'm delighted to release the first half of my new textbook in human genetics:
web.stanford.edu/group/pritch...
"An Owner's Guide to the Human Genome: an introduction to human population genetics, variation and disease"
web.stanford.edu/group/pritch...
"An Owner's Guide to the Human Genome: an introduction to human population genetics, variation and disease"
An Owner's Guide to the Human Genome
An Owner's Guide to the Human Genome
web.stanford.edu
October 1, 2023 at 10:53 PM
I'm delighted to release the first half of my new textbook in human genetics:
web.stanford.edu/group/pritch...
"An Owner's Guide to the Human Genome: an introduction to human population genetics, variation and disease"
web.stanford.edu/group/pritch...
"An Owner's Guide to the Human Genome: an introduction to human population genetics, variation and disease"
Excited to share that I will be starting my lab as faculty at Boston Children’s Hospital and Harvard Medical School
in July 2024! We will seek a quantitative understanding of gene expression control in development and resulting “tipping points” in disease. Please reach out if interested!
in July 2024! We will seek a quantitative understanding of gene expression control in development and resulting “tipping points” in disease. Please reach out if interested!
September 22, 2023 at 9:38 PM
Excited to share that I will be starting my lab as faculty at Boston Children’s Hospital and Harvard Medical School
in July 2024! We will seek a quantitative understanding of gene expression control in development and resulting “tipping points” in disease. Please reach out if interested!
in July 2024! We will seek a quantitative understanding of gene expression control in development and resulting “tipping points” in disease. Please reach out if interested!
Reposted by Sahin Naqvi
We're looking for a postdoc! Cool ERC-funded project digging into gene dosage variation with CRISPR+sc+computational methods. Dynamic environment at KTH / SciLifeLab Stockholm campus, plus interactions with our New York team. Apply or email for more info:
kth.varbi.com/se/what:job/...
kth.varbi.com/se/what:job/...
September 13, 2023 at 10:07 AM
We're looking for a postdoc! Cool ERC-funded project digging into gene dosage variation with CRISPR+sc+computational methods. Dynamic environment at KTH / SciLifeLab Stockholm campus, plus interactions with our New York team. Apply or email for more info:
kth.varbi.com/se/what:job/...
kth.varbi.com/se/what:job/...
Excited to present our recent work on TF dosage sensitivity (www.nature.com/articles/s41...) and a sneak peak at what’s in the pipeline at the Fragile Nucleosome series, tomorrow (Wed) 9 AM PST! Register here: generegulation.org/fragile-nucl...
Fragile Nucleosome – Gene Regulation – Teif Lab
generegulation.org
September 13, 2023 at 12:07 AM
Excited to present our recent work on TF dosage sensitivity (www.nature.com/articles/s41...) and a sneak peak at what’s in the pipeline at the Fragile Nucleosome series, tomorrow (Wed) 9 AM PST! Register here: generegulation.org/fragile-nucl...