We are building upon this approach in my lab @bostonchildrens.bsky.social @harvardmed.bsky.social and are recruiting at all levels: if interested see naqvilab.org and reach out!

Relative to the preprint, we added enhancer reporter assays testing the effect of homotypic binding on SOX9 dosage response, as well as analyses of inferred nucleosome positioning as a function of TWIST1 dosage

Congrats Ryan!

Thanks Benoit! Likewise, I have been following your work on cardiac TFs for a while and look forward to the next iteration! Hope to run into you at a conference or elsewhere in the future

We’re also happy to hear any other questions and feedback from you and your lab - email may be easier. sahin dot naqvi at childrens dot harvard dot edu

Hi Benoit, thanks for pointing this out. In almost all of the cases (I think) you’re referring to, N (which we do provide) is so high that every comp. is p<2.2e-16, so we focused on the distribution of values instead. But we should have still indicated p-values. Will do in the accepted version.

Looking forward to being neighbors, Ryan!

Congratulations Vijay!