Ruben van Boxtel
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rubenvanboxtel.bsky.social
Ruben van Boxtel
@rubenvanboxtel.bsky.social
Somatic evolution in childhood cancer
Group leader @Prinses Máxima Center for Pediatric Oncology
and @Oncode Institute
Reposted by Ruben van Boxtel
Exciting news: Thanks to funding from KWF - Alpe d'HuZes, two new studies are underway! Ruben van Boxtel, Maarten Geurts and Friso Calkoen focus on predicting the effectiveness of CAR T-cell therapy for children with B-ALL. Jorik van Rijn explores new paths to develop CAR T-cell therapy for T-LBLL.
December 13, 2024 at 1:25 PM
Reposted by Ruben van Boxtel
**Clinical Cancer Genomics Conference**
First of an annual recurring series. It will be a very important meeting for the advance of clinical implementation of cancer genomics.

Proud to be part of it.

March 20th-21st 2025 in Amsterdam.

Registration open: www.ccg2025.eu
#CCG2025
December 9, 2024 at 3:33 PM
Reposted by Ruben van Boxtel
I'm pleased to share that I will be speaking at the Clinical Cancer Genomics meeting, taking place on the 20th-21st of March 2025 in Amsterdam. Register now to join me and discuss the latest developments with leading experts in the field: www.ccg2025.eu #CCG2025
December 9, 2024 at 7:46 AM
Reposted by Ruben van Boxtel
Spread the word! Registration for the "Mutations in Time and Space" conference is open. The meeting is all about the origins, patterns, and consequences of mutations across cells, individuals, populations, species. Abstract submission deadline is Jan 17th broadinstitute.swoogo.com/mits2025/597...
December 6, 2024 at 2:29 PM
Reposted by Ruben van Boxtel
Don't miss out. Two more weeks for abstract submission for the Clinical Cancer Genomics meeting #CCG2025. We have an exciting line-up of speakers! Come and join leading scientists and medical specialists in cancer genomics in Amsterdam on March 20 and 21.
December 3, 2024 at 8:08 AM
Reposted by Ruben van Boxtel
Science Magazine wrote a news article about our latest preprint, featuring @johnprensner.bsky.social @thomasmartinez.bsky.social Alan Saghatelian, Ji-Young Youn, Ami Bhatt, Jon Mudge, and more: www.science.org/content/arti...

Preprint: www.biorxiv.org/content/10.1...

🔎microproteins #darkproteome
‘Dark proteome’ survey reveals thousands of new human genes
Database confirms that overlooked segments of the genome code for a multitude of tiny proteins
www.science.org
November 26, 2024 at 1:46 PM
We are looking for a motivated Postdoctoral Researcher to work on cutting-edge computational genomics projects in our lab!
werkenbijprinsesmaximacentrum.nl/vacature/pos...
Postdoc Computational Genomics - Werken bij Prinses Maxima Centrum
The Position We are seeking a highly motivated computational biologist with a PhD in genomics, cancer biology, or related fields, ideally with experience in single-cell genomics and machine learning. ...
werkenbijprinsesmaximacentrum.nl
November 26, 2024 at 5:13 PM
Reposted by Ruben van Boxtel
Resharing here a recent X post. In this preprint, we introduce an improved version of NanoSeq, a duplex sequencing protocol with <5 errors per billion bp in single DNA molecules, and use it to study the somatic mutation landscape of oral epithelium in >1000 people. 1/ www.medrxiv.org/content/10.1...
Somatic mutation and selection at epidemiological scale
As we age, many tissues become colonised by microscopic clones carrying somatic driver mutations ([1][1]–[10][2]. Some of these clones represent a first step towards cancer whereas others may contribu...
www.medrxiv.org
November 20, 2024 at 2:28 PM
Reposted by Ruben van Boxtel
Join us for the Clinical Cancer Genomics Conference in Amsterdam in March 2025. #CCG2025
November 18, 2024 at 4:22 PM