Roham Parsa
@rohamparsa.bsky.social
Group Leader at the Chan Zuckerberg Biohub New York. Adjunct Assistant Professor at The Rockefeller University. Immunologist with a passion for T cells!
parsalab.org
parsalab.org
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Roham Parsa
@rohamparsa.bsky.social
· Aug 29
Excited to share our new preprint! We studied how T cells are functionally & clonally shaped across organs over time. With the new TRACK mice, we genetically label recently activated T cells with tdTomato and track their migration across tissues. #immunology #science www.biorxiv.org/content/10.1...
Reposted by Roham Parsa
Just a few days left for scholarship and short talk submissions!
Science, snow, and exciting advances in fungal and immunology research🔬 🍄❄️Claim your spot! #KSFUNGALPATH26 www.keystonesymposia.org/conferences/...
Science, snow, and exciting advances in fungal and immunology research🔬 🍄❄️Claim your spot! #KSFUNGALPATH26 www.keystonesymposia.org/conferences/...
Fungal Pathogens: Emerging Threats and Future Challenges | Keystone Symposia
Join us at the Keystone Symposia on Fungal Pathogens: Emerging Threats and Future Challenges, January 2026, in Breckenridge, with field leaders!
www.keystonesymposia.org
September 12, 2025 at 9:56 PM
Just a few days left for scholarship and short talk submissions!
Science, snow, and exciting advances in fungal and immunology research🔬 🍄❄️Claim your spot! #KSFUNGALPATH26 www.keystonesymposia.org/conferences/...
Science, snow, and exciting advances in fungal and immunology research🔬 🍄❄️Claim your spot! #KSFUNGALPATH26 www.keystonesymposia.org/conferences/...
Excited to share our new preprint! We studied how T cells are functionally & clonally shaped across organs over time. With the new TRACK mice, we genetically label recently activated T cells with tdTomato and track their migration across tissues. #immunology #science www.biorxiv.org/content/10.1...
August 29, 2025 at 12:05 PM
Excited to share our new preprint! We studied how T cells are functionally & clonally shaped across organs over time. With the new TRACK mice, we genetically label recently activated T cells with tdTomato and track their migration across tissues. #immunology #science www.biorxiv.org/content/10.1...
Hi, we are looking for two motivated postdocs to join our group!
job-boards.greenhouse.io/chanzuckerbe...
job-boards.greenhouse.io/chanzuckerbe...
job-boards.greenhouse.io/chanzuckerbe...
job-boards.greenhouse.io/chanzuckerbe...
Research Scholar, T cell Tissue Adaptation and Residency (Parsa Group - Biohub NY)
New York, New York, United States
job-boards.greenhouse.io
April 7, 2025 at 10:36 PM
Hi, we are looking for two motivated postdocs to join our group!
job-boards.greenhouse.io/chanzuckerbe...
job-boards.greenhouse.io/chanzuckerbe...
job-boards.greenhouse.io/chanzuckerbe...
job-boards.greenhouse.io/chanzuckerbe...
Reposted by Roham Parsa
🚨New paper alert! 🚨 Our latest work in
@cp-immunity.bsky.social shows that Ark313, an evolved AAV variant enables in vivo genetic engineering of murine T cells! 🧵👇
sciencedirect.com/science/arti...
@cp-immunity.bsky.social shows that Ark313, an evolved AAV variant enables in vivo genetic engineering of murine T cells! 🧵👇
sciencedirect.com/science/arti...
In vivo engineering of murine T cells using the evolved adeno-associated virus variant Ark313
Genetic engineering of T cells in mouse models is essential for investigating immune mechanisms. We aimed to develop an approach to manipulate T cells…
sciencedirect.com
February 4, 2025 at 8:50 PM
🚨New paper alert! 🚨 Our latest work in
@cp-immunity.bsky.social shows that Ark313, an evolved AAV variant enables in vivo genetic engineering of murine T cells! 🧵👇
sciencedirect.com/science/arti...
@cp-immunity.bsky.social shows that Ark313, an evolved AAV variant enables in vivo genetic engineering of murine T cells! 🧵👇
sciencedirect.com/science/arti...
We're recruiting new Group Leaders and Platform Leaders at Chan Zuckerberg Biohub New York! Our mission: to decode and understand the language of the immune system to better detect and treat cancer, autoimmunity, and neurodegenerative diseases.
www.czbiohub.org/careers/?loc...
#newPI #ScienceJobs
www.czbiohub.org/careers/?loc...
#newPI #ScienceJobs
Career Opportunities at the CZ Biohub Network
Find job openings at the CZ Biohub Network.
www.czbiohub.org
January 17, 2025 at 1:47 AM
We're recruiting new Group Leaders and Platform Leaders at Chan Zuckerberg Biohub New York! Our mission: to decode and understand the language of the immune system to better detect and treat cancer, autoimmunity, and neurodegenerative diseases.
www.czbiohub.org/careers/?loc...
#newPI #ScienceJobs
www.czbiohub.org/careers/?loc...
#newPI #ScienceJobs
Reposted by Roham Parsa
I am excited to share our study showing how the immune system strikes a delicate balance between tolerating food and defending against helminth infections.
www.science.org/doi/10.1126/....
www.science.org/doi/10.1126/....
Identification of antigen-presenting cell–T cell interactions driving immune responses to food
The intestinal immune system must concomitantly tolerate food and commensals and protect against pathogens. Antigen-presenting cells (APCs) orchestrate these immune responses by presenting luminal ant...
www.science.org
December 21, 2024 at 2:09 AM
I am excited to share our study showing how the immune system strikes a delicate balance between tolerating food and defending against helminth infections.
www.science.org/doi/10.1126/....
www.science.org/doi/10.1126/....
Beautiful work from my talented friend @cicacanesso.bsky.social
#Immunology by First release now @science.org
Identification of APCs in the gut that promote Treg differentiation and how tolerance to food antigens is influenced by helminth infection
https://buff.ly/3DjNQ1e
By Maria Canesso, @danmucida.bsky.social , @victora.bsky.social and colleagues.
Identification of APCs in the gut that promote Treg differentiation and how tolerance to food antigens is influenced by helminth infection
https://buff.ly/3DjNQ1e
By Maria Canesso, @danmucida.bsky.social , @victora.bsky.social and colleagues.
December 20, 2024 at 12:16 PM
Beautiful work from my talented friend @cicacanesso.bsky.social
We are looking for a Research Assistant! Come and build a great science team with me! #STEMjobs #ImmunoSky
job-boards.greenhouse.io/chanzuckerbe...
job-boards.greenhouse.io/chanzuckerbe...
Research Associate - Parsa Group
New York, New York, United States
job-boards.greenhouse.io
December 17, 2024 at 2:40 PM
We are looking for a Research Assistant! Come and build a great science team with me! #STEMjobs #ImmunoSky
job-boards.greenhouse.io/chanzuckerbe...
job-boards.greenhouse.io/chanzuckerbe...
Reposted by Roham Parsa
Today we report that an engineered skin bacterium, swabbed gently on the head of a mouse, can unleash a potent antibody response against a pathogen. Could lead to topical vaccines that are applied in a cream. @djenetbousbaine.bsky.social led the charge... @natureportfolio.bsky.social 1/55
December 11, 2024 at 4:29 PM
Today we report that an engineered skin bacterium, swabbed gently on the head of a mouse, can unleash a potent antibody response against a pathogen. Could lead to topical vaccines that are applied in a cream. @djenetbousbaine.bsky.social led the charge... @natureportfolio.bsky.social 1/55
Mug competition with @cyrilpedia.bsky.social , gift to me from @danmucida.bsky.social lab, immunologists best friend
December 6, 2024 at 12:54 PM
Mug competition with @cyrilpedia.bsky.social , gift to me from @danmucida.bsky.social lab, immunologists best friend
Anyone knows where I can find some influenza PR8 proteins, specifically - M2, PB2 and PA… I’ll send you some top quality Swedish candy :)
November 30, 2024 at 3:15 AM
Anyone knows where I can find some influenza PR8 proteins, specifically - M2, PB2 and PA… I’ll send you some top quality Swedish candy :)
Great podcast! Everyone—graduate students, postdocs, and new PIs—should listen to this episode!
New Night Science Podcast episode! Stanford's Michael Fischbach talks about choosing a research problem, managing risks, and turning crises into opportunities; as discussed in his Cell paper "Problem choice and decision trees in science and engineering"
www.buzzsprout.com/1744020/epis...
www.buzzsprout.com/1744020/epis...
66 | Michael Fischbach and the scientific decision tree - Night Science
In this episode, Stanford professor Michael Fischbach discusses insights from his course on how to choose meaningful research problems. Highlights include:- Invest time in problem selection: Spend mor...
www.buzzsprout.com
November 29, 2024 at 4:04 PM
Great podcast! Everyone—graduate students, postdocs, and new PIs—should listen to this episode!
I’m looking for a postdoc to join my group here at Chan Zuckerberg Biohub NY! This position offers the chance to delve deeply into the dynamic and functional behavior of T cells, exploring how their fate decisions shape immune responses in health and disease.
More information at parsalab.science
More information at parsalab.science
The Parsa Laboratory at CZ Biohub New York
The Parsa laboratory investigates the functional and clonal dynamics of T cells during various immune responses. Using innovative genetic approaches, we will precisely track and analyze the behavior of polyclonal perturbation-specific T cells over time and space. We seek to uncover the rules governing the development of effector and memory T cells, ultimately enhancing our understanding of adaptive immunity and advancing therapies for various diseases, including cancer and autoimmunity.
parsalab.science
November 28, 2024 at 4:27 PM
I’m looking for a postdoc to join my group here at Chan Zuckerberg Biohub NY! This position offers the chance to delve deeply into the dynamic and functional behavior of T cells, exploring how their fate decisions shape immune responses in health and disease.
More information at parsalab.science
More information at parsalab.science
Reposted by Roham Parsa
PD-1 and CD73 on naive CD4+ T cells synergistically limit responses to self
www.nature.com/articles/s41...
www.nature.com/articles/s41...
November 22, 2024 at 3:49 PM
PD-1 and CD73 on naive CD4+ T cells synergistically limit responses to self
www.nature.com/articles/s41...
www.nature.com/articles/s41...
I’m very fascinated about this study showing stem cell-like effector CD4 T cells that can become the classic T helper subsets. In tumors, Tregs suppress these cells, blocking Th1 seeding and anti-tumor effects! Jenkins lab also recently described a similar CD4 phenotype with different implications.
Differentiation fate of a stem-like CD4 T cell controls immunity to cancer - Nature
A population of tumour-specific PD1+TCF1+ CD4 T cells in tumour-draining lymph nodes is capable of self-renewal and differentiation into CD4 effector cells, thereby controlling CD8 T cell activity.
www.nature.com
November 19, 2024 at 4:04 AM
I’m very fascinated about this study showing stem cell-like effector CD4 T cells that can become the classic T helper subsets. In tumors, Tregs suppress these cells, blocking Th1 seeding and anti-tumor effects! Jenkins lab also recently described a similar CD4 phenotype with different implications.
Reposted by Roham Parsa
Still thinking about gut biogeography.
Gut biogeography of the bacterial microbiota - Nature Reviews Microbiology
The gut microbiota has a strong impact on host physiology. In this Review, Mazmanian and colleagues describe the mechanisms that control the biogeography of bacteria in the gut and discuss the importa...
www.nature.com
November 16, 2024 at 3:51 PM
Still thinking about gut biogeography.
Reposted by Roham Parsa
Here is out first attempt to understand #TCR #repertoire in human tissues -Tissue determinants of the human T cell receptor repertoire Around 6 million T cells profiled at #single #cell #level www.biorxiv.org/content/10.1...
Tissue determinants of the human T cell receptor repertoire
98% of T cells reside in tissues, yet nearly all human T cell analyses are performed from peripheral blood. We single-cell sequenced 5.7 million T cells from ten donors’ autologous blood and tonsils a...
www.biorxiv.org
November 15, 2024 at 2:13 PM
Here is out first attempt to understand #TCR #repertoire in human tissues -Tissue determinants of the human T cell receptor repertoire Around 6 million T cells profiled at #single #cell #level www.biorxiv.org/content/10.1...