Rhett Rautsaw
@reptilerhett.bsky.social
All views are my own
Field Applications Bioinformatic Support (FABS) Scientist @pacbio.bsky.social
PostDoc: Tasmanian Devils @wsupullman.bsky.social & @usouthflorida.bsky.social
PhD: 🐍 venom evolution @SnakeLabClemson
Field Applications Bioinformatic Support (FABS) Scientist @pacbio.bsky.social
PostDoc: Tasmanian Devils @wsupullman.bsky.social & @usouthflorida.bsky.social
PhD: 🐍 venom evolution @SnakeLabClemson
Reposted by Rhett Rautsaw
Jeremy Schmutz at HudsonAlpha is the last talk of the @pacbio.bsky.social workshop at #PAG33 to talk about the cornucopia of genomics PacBio provides including beta testing results from SPRQ-Nx reusable SMRT Cells.
January 12, 2026 at 10:38 PM
Jeremy Schmutz at HudsonAlpha is the last talk of the @pacbio.bsky.social workshop at #PAG33 to talk about the cornucopia of genomics PacBio provides including beta testing results from SPRQ-Nx reusable SMRT Cells.
Christine Queitsch is up at @pacbio.bsky.social workshop at #PAG33 to talk about Fiber-Seq in Maize to look at chromatin accessibility, protein occupancy, and nucleosome positioning from a single HiFi experiment along with your long read sequencing data. @epicypher.bsky.social
January 12, 2026 at 10:22 PM
Christine Queitsch is up at @pacbio.bsky.social workshop at #PAG33 to talk about Fiber-Seq in Maize to look at chromatin accessibility, protein occupancy, and nucleosome positioning from a single HiFi experiment along with your long read sequencing data. @epicypher.bsky.social
Reposted by Rhett Rautsaw
Christine Queitsch walks us through Fiber-Seq in maize which is greatly increasing our understanding of the regulatory landscape of maize.
January 12, 2026 at 10:18 PM
Christine Queitsch walks us through Fiber-Seq in maize which is greatly increasing our understanding of the regulatory landscape of maize.
Brooke Peterson-Burch up next at @pacbio.bsky.social Workshop at #PAG33 to talk about gene prediction in crops using Kinnex Iso-Seq.
January 12, 2026 at 10:01 PM
Brooke Peterson-Burch up next at @pacbio.bsky.social Workshop at #PAG33 to talk about gene prediction in crops using Kinnex Iso-Seq.
Sheina Sim is up now @pacbio.bsky.social workshop at #PAG33 to talk about CiFi and multiomic holistic genomes in fruit flies.
January 12, 2026 at 9:43 PM
Sheina Sim is up now @pacbio.bsky.social workshop at #PAG33 to talk about CiFi and multiomic holistic genomes in fruit flies.
Reposted by Rhett Rautsaw
See how Kendall Lee at HAIB and Veil Genomics is advancing Polyploid Genomics in blueberries using HiFi sequencing. A single Revio cell produces enough data for a high-quality assembly of a single blueberry, or low pass data on 12 individuals for population scale studies.
#PacBio #PAG33 #Revio
#PacBio #PAG33 #Revio
January 12, 2026 at 9:32 PM
Kendall Lee from Veil Genomics is here! Time to learn about Long Read Low Pass sequencing along with some CiFi of Blueberries! 🫐 #PAG33 @pacbio.bsky.social
January 12, 2026 at 9:26 PM
Kendall Lee from Veil Genomics is here! Time to learn about Long Read Low Pass sequencing along with some CiFi of Blueberries! 🫐 #PAG33 @pacbio.bsky.social
The room is filling up! If you’re not here you’re missing out on exciting updates on Kinnex Iso-Seq, Fiber-Seq chromatin accessibility, CiFi for HiFi based HiC scaffolding, and Low-Pass population sequencing. @pacbio.bsky.social @epicypher.bsky.social #PAG33
January 12, 2026 at 9:19 PM
The room is filling up! If you’re not here you’re missing out on exciting updates on Kinnex Iso-Seq, Fiber-Seq chromatin accessibility, CiFi for HiFi based HiC scaffolding, and Low-Pass population sequencing. @pacbio.bsky.social @epicypher.bsky.social #PAG33
Jake is starting us off to tell us about the latest updates from @pacbio.bsky.social including SPRQ-Nx to drop costs with reusable SMRT Cells. #PAG33
January 12, 2026 at 9:06 PM
Jake is starting us off to tell us about the latest updates from @pacbio.bsky.social including SPRQ-Nx to drop costs with reusable SMRT Cells. #PAG33
PacBio workshop happening now at #PAG33. @pacbio.bsky.social. Come to learn more about multiomics and everything you can do with HiFi sequencing. #TheresHiFiForThat
Come join us!
Come join us!
January 12, 2026 at 8:57 PM
PacBio workshop happening now at #PAG33. @pacbio.bsky.social. Come to learn more about multiomics and everything you can do with HiFi sequencing. #TheresHiFiForThat
Come join us!
Come join us!
Reposted by Rhett Rautsaw
Team Animal seems to be winning this round 🐱🌱!
Swing by Booth 219 at PAG 2026 to cast your vote in the ultimate Plant vs. Animal showdown, see live demonstrations of our Vega sequencing system, and meet the PacBio experts behind the science.
#PacBio #PAG33 #Vega #AnimalGenomics #PlantGenomics
Swing by Booth 219 at PAG 2026 to cast your vote in the ultimate Plant vs. Animal showdown, see live demonstrations of our Vega sequencing system, and meet the PacBio experts behind the science.
#PacBio #PAG33 #Vega #AnimalGenomics #PlantGenomics
January 12, 2026 at 5:18 PM
Team Animal seems to be winning this round 🐱🌱!
Swing by Booth 219 at PAG 2026 to cast your vote in the ultimate Plant vs. Animal showdown, see live demonstrations of our Vega sequencing system, and meet the PacBio experts behind the science.
#PacBio #PAG33 #Vega #AnimalGenomics #PlantGenomics
Swing by Booth 219 at PAG 2026 to cast your vote in the ultimate Plant vs. Animal showdown, see live demonstrations of our Vega sequencing system, and meet the PacBio experts behind the science.
#PacBio #PAG33 #Vega #AnimalGenomics #PlantGenomics
I’ll at #PAG33 with @pacbio.bsky.social. Don’t forget to stop by the booth or setup a meeting with us to talk about how PacBio HiFi sequencing can enhance your research!
bit.ly/4aLRhg4
bit.ly/4aLRhg4
January 8, 2026 at 12:22 AM
I’ll at #PAG33 with @pacbio.bsky.social. Don’t forget to stop by the booth or setup a meeting with us to talk about how PacBio HiFi sequencing can enhance your research!
bit.ly/4aLRhg4
bit.ly/4aLRhg4
Reposted by Rhett Rautsaw
Excited to share our final accepted version of the CiFi method out today: www.nature.com/articles/s41...
December 8, 2025 at 5:54 PM
Excited to share our final accepted version of the CiFi method out today: www.nature.com/articles/s41...
Reposted by Rhett Rautsaw
Countdown starts now.
The genomics series we’ve all been waiting for – a #PacBio original series.
Trailer’s out.
Premiere’s coming.
Add it to your watchlist 👇
🔗 bit.ly/4oLrOXu
The genomics series we’ve all been waiting for – a #PacBio original series.
Trailer’s out.
Premiere’s coming.
Add it to your watchlist 👇
🔗 bit.ly/4oLrOXu
December 4, 2025 at 6:30 PM
Countdown starts now.
The genomics series we’ve all been waiting for – a #PacBio original series.
Trailer’s out.
Premiere’s coming.
Add it to your watchlist 👇
🔗 bit.ly/4oLrOXu
The genomics series we’ve all been waiting for – a #PacBio original series.
Trailer’s out.
Premiere’s coming.
Add it to your watchlist 👇
🔗 bit.ly/4oLrOXu
Reposted by Rhett Rautsaw
Annual Mabel with a Lego PacBio Sequencer. This time the Vega, but we also have the Revio and Sequel Lego edition.
November 22, 2025 at 10:37 PM
Annual Mabel with a Lego PacBio Sequencer. This time the Vega, but we also have the Revio and Sequel Lego edition.
Reposted by Rhett Rautsaw
Long-read genome sequencing is new first-tier generic test in diagnostics of rare diseases
So satisfying to see a long journey end in best-possible diagnostic test for patients with rare diseases @radboudumc.bsky.social.
www.radboudumc.nl/en/news-item...
(1/n)
So satisfying to see a long journey end in best-possible diagnostic test for patients with rare diseases @radboudumc.bsky.social.
www.radboudumc.nl/en/news-item...
(1/n)
World first: Radboudumc pioneers new genetic test in clinical practice - New test is faster, more efficient, and provides more diagnoses for rare diseases
17 November 2025
www.radboudumc.nl
November 17, 2025 at 8:29 AM
Long-read genome sequencing is new first-tier generic test in diagnostics of rare diseases
So satisfying to see a long journey end in best-possible diagnostic test for patients with rare diseases @radboudumc.bsky.social.
www.radboudumc.nl/en/news-item...
(1/n)
So satisfying to see a long journey end in best-possible diagnostic test for patients with rare diseases @radboudumc.bsky.social.
www.radboudumc.nl/en/news-item...
(1/n)
Reposted by Rhett Rautsaw
SPRQ-Nx is coming to #Revio next year. It is expected to reduce whole genome sequencing costs by up to 40% to $300–$350 per genome or lower at scale.
#PacBio #ASHG25 #HiFisequencing #ASHG
#PacBio #ASHG25 #HiFisequencing #ASHG
October 17, 2025 at 4:36 PM
SPRQ-Nx is coming to #Revio next year. It is expected to reduce whole genome sequencing costs by up to 40% to $300–$350 per genome or lower at scale.
#PacBio #ASHG25 #HiFisequencing #ASHG
#PacBio #ASHG25 #HiFisequencing #ASHG
Reposted by Rhett Rautsaw
The #PacBioBlockParty is in full swing 🎉 Guests are rolling in, the music’s on, and the fun’s just getting started! Virtual darts, bowling, food, a live DJ, and more await. Let’s celebrate together!
#ASHG25 #PacBio #ASHG
#ASHG25 #PacBio #ASHG
October 16, 2025 at 1:26 AM
The #PacBioBlockParty is in full swing 🎉 Guests are rolling in, the music’s on, and the fun’s just getting started! Virtual darts, bowling, food, a live DJ, and more await. Let’s celebrate together!
#ASHG25 #PacBio #ASHG
#ASHG25 #PacBio #ASHG
Reposted by Rhett Rautsaw
Short reads…who needs em? Start bringing ALL your NGS projects into the long read era with cheaper sequencing, simultaneous methylation, greater insights, and more answers to your biological questions. PacBio’s got you covered.
October 15, 2025 at 12:27 AM
Short reads…who needs em? Start bringing ALL your NGS projects into the long read era with cheaper sequencing, simultaneous methylation, greater insights, and more answers to your biological questions. PacBio’s got you covered.
Reposted by Rhett Rautsaw
Just in: #PacBio HiFi long-read sequencing is powering the National Institute on Aging’s Long Life Family Study.
Up to 7,800 genomes and epigenomes will be sequenced on Revio systems to uncover rare variants, methylation patterns, and other factors linked to healthy aging.
🔗 bit.ly/3IUDdFo
Up to 7,800 genomes and epigenomes will be sequenced on Revio systems to uncover rare variants, methylation patterns, and other factors linked to healthy aging.
🔗 bit.ly/3IUDdFo
October 8, 2025 at 3:02 PM
Just in: #PacBio HiFi long-read sequencing is powering the National Institute on Aging’s Long Life Family Study.
Up to 7,800 genomes and epigenomes will be sequenced on Revio systems to uncover rare variants, methylation patterns, and other factors linked to healthy aging.
🔗 bit.ly/3IUDdFo
Up to 7,800 genomes and epigenomes will be sequenced on Revio systems to uncover rare variants, methylation patterns, and other factors linked to healthy aging.
🔗 bit.ly/3IUDdFo
Reposted by Rhett Rautsaw
I'm heading to Boston for #ASHG25 tomorrow, let me know if you'd like to chat about using HiFi sequencing for mitochondrial analyses, pharmacogenomics, or anything else!
ICYMI, also happy to discuss our new Aardvark tool for benchmarking :)
ICYMI, also happy to discuss our new Aardvark tool for benchmarking :)
I'm excited to share our pre-print about a new variant benchmarking tool we've been working on for the past few months!
Aardvark: Sifting through differences in a mound of variants
GitHub: github.com/PacificBiosc...
Some highlights in this thread:
1/N
Aardvark: Sifting through differences in a mound of variants
GitHub: github.com/PacificBiosc...
Some highlights in this thread:
1/N
October 13, 2025 at 1:48 PM
I'm heading to Boston for #ASHG25 tomorrow, let me know if you'd like to chat about using HiFi sequencing for mitochondrial analyses, pharmacogenomics, or anything else!
ICYMI, also happy to discuss our new Aardvark tool for benchmarking :)
ICYMI, also happy to discuss our new Aardvark tool for benchmarking :)