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RAPP OptoElectronic
@rappopto.bsky.social
RAPP OptoElectronic GmbH
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Outstanding work by the entire team - congratulations to all authors involved!

It’s great to see the precision and performance of the
@rappopto.bsky.social Caliburn ablation laser in action — the level of detail in those cuts is genuinely impressive.
Final version of our paper on ciliary metachronal waves out now in Science Advances! doi.org/10.1126/scia...

This is the main thesis work of my PhD student Rebecca Poon, who caught many #platnereis larvae and tirelessly ablated them with a laser. THREAD
October 20, 2025 at 11:48 AM
Beautiful pictures—thanks for sharing, @kasiagrochowska.bsky.social

Congratulations again on the new system. It's great to see that it's being put into action so quickly and successfully.

We look forward to more great pictures in the future ;)
The beauty of these images will never stop amazimg me. Hippocampal (CA1) neurons expressing an artificial cytoplasmic protein partially targeted to lysosomes (black dots).
September 4, 2025 at 11:26 AM
@rappopto.bsky.social was more than happy to support such an incredible meeting.
Grateful to have had the chance to connect to many old friends and to make new ones at the incredible "Bee and Fly Neuroethology Meeting" at the Harnack house of the @maxplanck.de in Berlin.
The energy around new discoveries and brilliant scientists was infectious, and inspiring.
September 1, 2025 at 11:16 AM
We're proud that the FRAP technology from @rappopto.bsky.social supported this discovery by enabling high-resolution analysis of condensate dynamics.

Congrats to the authors @annaleder.bsky.social and others of the Hiller Lab University of Basel
New paper alert! Stellar work by brilliant lead first author @annaleder.bsky.social together with project leader @masgu.bsky.social reveals a groundbreaking discovery: PDIA6 forms multi-chaperone condensates creating "folding factories" in the ER. www.nature.com/articles/s41...
August 22, 2025 at 12:06 PM
It was a splendid time with @kasiagrochowska.bsky.social and Long Yan from Florida Lifetime Imaging.

It’s been a great pleasure working together - thank you @kasiagrochowska.bsky.social and the team for the fruitful collaboration!

All the best for terrific data and exciting endeavors to come 🙌
Exciting week with calibration of the FLIM module!
August 18, 2025 at 7:37 AM
Wonderful work by @viji-draviam.bsky.social and team.
Congratulations on the publication!

We're honored to be cited in your work—exciting to see our contributions supporting cutting-edge research. Looking forward to following your continued discoveries!
August 6, 2025 at 6:44 PM
New insights: Muscles grow by splitting sarcomeres! 💥 Using our UGA-42 #photomanipulation, the authors showed sarcomeres divide under tension to stay functional during development.

Congrats to all authors on a beautiful scientific paper!
SARCOMERES divide! Mechanism how muscles grow while contracting - daughter sarcomeres appear everywhere. Seen live, registered on our cover. Pioneered by @clementrodier.bsky.social @friedrich-group.bsky.social Ian Estabrook @ibdm.bsky.social $ by @hfspo.bsky.social www.science.org/doi/10.1126/...
August 4, 2025 at 8:13 AM
A beautiful new paper about IP3 Uncaging with the UGA-42 system:

Endothelial cells pass signals by triggering receptors on neighbors—not through gap junctions.
A new way vessels stay in sync!

by Buckley, Zhang, Lee, Wilson & McCarron 2025 FASEB

faseb.onlinelibrary.wiley.com/doi/10.1096/...
faseb.onlinelibrary.wiley.com
July 24, 2025 at 7:32 AM
Did you miss the talk by @swarnck.bsky.social from @rappopto.bsky.social at the #laserworldofphotonics in Munich yesterday?

Visit him at the Chroma booth B2.446!
And talk #photomanipulation

Zain Ali, Georg Draude, Almut Bailly (all Chroma GmbH), Melissa (89North Inc.) & @swarnck.bsky.social
June 27, 2025 at 7:07 AM
Reposted by RAPP OptoElectronic
I'm thrilled to announce that I've been invited to give a talk on the #Biophotonics and Medical Applications Forum (B2.350) at #LASER World-of-Photonics in #Munich.
Come by on June 26, 2025, from 10:40 to 11:00 to hear about the "Latest Applications in Fast and Precise #Photomanipulation".
June 17, 2025 at 11:29 AM
Come say hello at our joint booth at #ELMI2025

There's some great coffee and beer to celebrate 25 years of @eurobioimaging.bsky.social

Just walk up the helix and grab yours.

We're happy to chat

Toptica
Chroma
@microscopy.confocalnl.com
@ultimeyes.bsky.social by CAIRN
&
@rappopto.bsky.social
June 5, 2025 at 6:48 AM
Reposted by RAPP OptoElectronic
Come say hello at our joint booth at #ELMI2025 — there's some great coffee and beer there to celebrate 25 years of #ELMI! Just walk up the helix and grab yours.

We're happy to chat.
ELMI @eulimi.bsky.social turns 25 next week – and we’re bringing cake (if the mouse leaves us any)...

See you at the 25th European Light Microscopy Initiative meeting at @embl.org w/ our friends Toptica, @microscopy.confocalnl.com, @ultimeyes.bsky.social by CAIRN GmbH, and Chroma Technology Corp.
June 4, 2025 at 2:34 PM
ELMI @eulimi.bsky.social turns 25 next week – and we’re bringing cake (if the mouse leaves us any)...

See you at the 25th European Light Microscopy Initiative meeting at @embl.org w/ our friends Toptica, @microscopy.confocalnl.com, @ultimeyes.bsky.social by CAIRN GmbH, and Chroma Technology Corp.
May 30, 2025 at 12:49 PM
Reposted by RAPP OptoElectronic
FRAP-in-SR for dynamic studies at 60nm resolution!! If you explore cell cycle, DNA damage or 53BP1, here are new tools for live-cell microscopy: a fruitful collaboration with @carlzeissstiftung.bsky.social for SIM2/diSIM and @rappopto.bsky.social for localised FRAP www.biorxiv.org/content/10.1...
FRAP-in-SR: Fluorescence recovery in the Super-Resolution regime reveals subcompartments of 53BP1 foci
We combine Lattice Structured Illumination Microscopy (diSIM/SIM2 with ~60 nm resolution), Lattice Light-sheet microscopy and Fluorescence Recovery After Photobleaching (FRAP) to explore 53BP1 dynamic...
www.biorxiv.org
May 8, 2025 at 2:00 PM
1/2
A stunning new paper from Deqing Kong & the Jörg Großhans lab dives deep into how cells change shape and reorganize during development. Their toolkit? Precision light from
@rappopto.bsky.social
And we’re thrilled our lasers played a key role.

www.cell.com/current-biol...
Synchronization in epithelial tissue morphogenesis
Richa et al. demonstrate that Tmc, a mechano-gated channel in vertebrate hearing, synchronizes cell dynamics in the epithelial amnioserosa of Drosophila embryos. Experimental data together with a data...
www.cell.com
May 8, 2025 at 7:31 AM
2/2 The study explores how localized Ca²⁺ signaling influences cellular dynamics using @rappopto.bsky.social 375 nm laser, and the Caliburn laser for microsurgical ablation of cell junctions - offering high spatial and temporal control.
Congrats to all authors involved.

www.cell.com/current-biol...
Synchronization in epithelial tissue morphogenesis
Richa et al. demonstrate that Tmc, a mechano-gated channel in vertebrate hearing, synchronizes cell dynamics in the epithelial amnioserosa of Drosophila embryos. Experimental data together with a data...
www.cell.com
May 8, 2025 at 7:30 AM
Welcome to our booth at #FOM2025

We are happy to talk to you about optical filters, laser illuminations, instrumentation for #photomanipulation, the openFrame microscope, and accessories.

Many thanks to Chroma Technology and 89North for hosting us.

Rapp OptoElectronic GmbH
Cairn Research LTd
April 15, 2025 at 6:50 AM
Our CEO @swarnck.bsky.social is experiencing the Chinese Cell Biology Community at #CSCB2025 in Zhuai.

He made new friends & e.g. saw the new Zeiss LSM Lightfield 4D.

Special thanks are due to our local partners & hosts Echo Li from Chroma Technologies and Siyuan Feng from Evident Scientific.
April 10, 2025 at 12:34 PM
Today, we were part of the Girls' and Boys' Day,
the “Girls' and Boys' Future Day”

A program to support stereotype-free career and study choices for all.

The pupils successfully completed the day with happiness and full of motivation, thanks to a great team @rappopto.bsky.social
April 3, 2025 at 12:28 PM
Our Applications Specialist Anja Zimmermann is on a tour with Jan Dolzer from our US-Partner Sutter Instrument @sutterinstrument.bsky.social.

On tour, Jan is giving a talk about "What is hidden under the noise" today at
@biodip.bsky.social
@crtd-tud.bsky.social
@cmcb-tud.bsky.social

👍👍
April 1, 2025 at 12:37 PM
#NWG2025 @neurowissg.bsky.social in Göttingen has started!

We are looking forward to talking to you.
Come by and take a look at our booth 39.
March 26, 2025 at 12:23 PM
@gerbi-gmb.de #TiM2025 in Münsingen is in full swing.

Iliya Stoev @kit.edu introducing #FLUCS photomanipulation to #TiM2025 participants.

We send our appreciation and thanks to Iliya, Britta Schroth-Diez @mpi-cbg.de, @mpi-cbg-lmf.bsky.social and Ines Höfer from Evident Scientific for support.
March 18, 2025 at 1:47 PM
Reposted by RAPP OptoElectronic
I'm thrilled to be presenting workshops on #FLUCS with our partners, Britta and Iliya. See you there!
Only 7 days left until #TiM2025! 🎉 We're super hyped! 🚀
Don't miss out – day tickets are still available! Grab yours now and join us for an unforgettable TiM! 🙌🔥
March 12, 2025 at 12:39 PM
Great preview of of our #FLUCS workshop next week #TIM2025 from @gerbi-gmb.de

Our CEO @swarnck.bsky.social and founder Gert Rapp as well as Simona Stelea are looking forward to meeting you there
Iliya Stoev showing us some impromptu FLUCS action on our new install from Rapp Optoelectronics, while prepping for a workshop with Rapp next week. Accompanied by our incoming tenure-track colleague Miha Modic
@paraspeckle.bsky.social and his student Jona Novljan
March 16, 2025 at 9:09 AM
The countdown is on! Just one day left until #TiM2025
@gerbi-gmb.de

Thanks to our great partners in the workshops, you have the chance to dive deeper into the #FLUCS universe #photomanipulation and experience the latest functionality to make your samples move as you want to.
March 16, 2025 at 9:03 AM