HillerLab
@hillerlab.bsky.social
Group of Prof Sebastian Hiller. Structural Biology Research Group. Unravelling Biomolecular Mechanisms. (run by students)
Excited to play a small role in this great paper: www.nature.com/articles/s41... by providing high quality purified chaperones by@masgu.bsky.social ! Huge congrats to first authors Tetiana Serdiuk and Yanick Fleischmann and the @picottilab.bsky.social and Roland Riek's lab for their work!
Alpha-synuclein interacts with regulators of ATP homeostasis in mitochondria - Nature Communications
Here, the authors show that physiological alpha-synuclein supports mitochondrial ATP homeostasis via interactions with ATP synthase and AK2, whereas its disease-linked mutants, truncated forms, and ag...
www.nature.com
August 18, 2025 at 2:11 PM
Excited to play a small role in this great paper: www.nature.com/articles/s41... by providing high quality purified chaperones by@masgu.bsky.social ! Huge congrats to first authors Tetiana Serdiuk and Yanick Fleischmann and the @picottilab.bsky.social and Roland Riek's lab for their work!
New paper alert! Stellar work by brilliant lead first author @annaleder.bsky.social together with project leader @masgu.bsky.social reveals a groundbreaking discovery: PDIA6 forms multi-chaperone condensates creating "folding factories" in the ER. www.nature.com/articles/s41...
August 11, 2025 at 9:10 AM
New paper alert! Stellar work by brilliant lead first author @annaleder.bsky.social together with project leader @masgu.bsky.social reveals a groundbreaking discovery: PDIA6 forms multi-chaperone condensates creating "folding factories" in the ER. www.nature.com/articles/s41...
Last day for our summer student Shreyan Datta, who has done great work during his one and a half months in our lab working on the Hsp70 functional cycle! If you are looking for a PhD student in the next few months, Shreyan Datta will be a great fit for any lab!
July 30, 2025 at 2:35 PM
Last day for our summer student Shreyan Datta, who has done great work during his one and a half months in our lab working on the Hsp70 functional cycle! If you are looking for a PhD student in the next few months, Shreyan Datta will be a great fit for any lab!
Congratulations to PhD student Marta and NMR Facility Manager Thomas for the publication of their great work on Photo-CIDNP in JACS ! pubs.acs.org/doi/full/10....
Predictions of Steady-State Photo-CIDNP Enhancement by Machine Learning
Photochemically induced dynamic nuclear polarization (photo-CIDNP) is a hyperpolarization method used to boost signal sensitivity in NMR spectroscopy. So far, there is no theory to predict the steady-...
pubs.acs.org
July 30, 2025 at 9:09 AM
Congratulations to PhD student Marta and NMR Facility Manager Thomas for the publication of their great work on Photo-CIDNP in JACS ! pubs.acs.org/doi/full/10....
Remember today !
Monday, June 16, 10 am EDT / 4 pm CEST, Second NexMR Webinar, Light-coupled NMR and photohyperpolarization for life sciences @nexmr.bsky.social free to register events.teams.microsoft.com/event/67fd26... #NMRchat #NMR 🧲
June 16, 2025 at 12:57 PM
Remember today !
Congratulations to @annaleder.bsky.social receiving the Shepherd price for her PhD work at today’s @biozentrum.unibas.ch symposium @biozentrum-phd.bsky.social . Stay tuned for the official paper release in the coming weeks.
June 12, 2025 at 12:40 PM
Congratulations to @annaleder.bsky.social receiving the Shepherd price for her PhD work at today’s @biozentrum.unibas.ch symposium @biozentrum-phd.bsky.social . Stay tuned for the official paper release in the coming weeks.
Reposted by HillerLab
Thrilled to share our new method in-cyclo NMR that lets us watch molecular machines in action — decoding molecular machine kinetics with atomic precision and exceptional time resolution in one go! 🚀 Check it out: doi.org/10.1038/s414... #NMR #StructuralBiology
June 2, 2025 at 9:16 AM
Thrilled to share our new method in-cyclo NMR that lets us watch molecular machines in action — decoding molecular machine kinetics with atomic precision and exceptional time resolution in one go! 🚀 Check it out: doi.org/10.1038/s414... #NMR #StructuralBiology
Introducing in-cyclo NMR, a breakthrough method led by first author @masgu.bsky.social at @biozentrum.unibas.ch! This method combines high-resolution NMR with ATP regeneration & phosphate removal to resolve kinetics & dynamics of molecular machines - all in one experiment! doi.org/10.1038/s414...
Mechanism of ATP hydrolysis in the Hsp70 BiP nucleotide-binding domain - Nature Communications
Mas et al introduce in-cyclo NMR to quantify all states and kinetic steps of Hsp70 chaperones ATPase cycle. In-cyclo NMR will enable studies of other molecular machines at an unprecedented level of de...
doi.org
June 2, 2025 at 8:41 AM
Introducing in-cyclo NMR, a breakthrough method led by first author @masgu.bsky.social at @biozentrum.unibas.ch! This method combines high-resolution NMR with ATP regeneration & phosphate removal to resolve kinetics & dynamics of molecular machines - all in one experiment! doi.org/10.1038/s414...
Great opportunity to hear how our Ph.D student Marta Stefanska brings light into NMR!
Monday, June 16, 10 am EDT / 4 pm CEST, Second NexMR Webinar, Light-coupled NMR and photohyperpolarization for life sciences @nexmr.bsky.social free to register events.teams.microsoft.com/event/67fd26... #NMRchat #NMR 🧲
May 22, 2025 at 5:55 PM
Great opportunity to hear how our Ph.D student Marta Stefanska brings light into NMR!
Tired of costly cloning software? Try IVA Prime: a free, game-changing tool for automated primer design in IVA cloning! Simplify complex cloning with one click, reduce errors, and save time. Visit www.ivaprime.com. doi.org/10.1093/nar/... collaboration with Prof. Javier Garcia Nafria
IVA Prime
www.ivaprime.com
May 6, 2025 at 12:06 PM
Tired of costly cloning software? Try IVA Prime: a free, game-changing tool for automated primer design in IVA cloning! Simplify complex cloning with one click, reduce errors, and save time. Visit www.ivaprime.com. doi.org/10.1093/nar/... collaboration with Prof. Javier Garcia Nafria
Reposted by HillerLab
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Great meeting so many inspiring colleagues and friends from the #NMR community at this year’s @enc-conference.org in Asilomar! I rarely travel to the US—trying to keep my carbon footprint low. But how big is the footprint of a #conference like ENC/ISMAR 2025? I analyzed the data. 🧵👇
Great meeting so many inspiring colleagues and friends from the #NMR community at this year’s @enc-conference.org in Asilomar! I rarely travel to the US—trying to keep my carbon footprint low. But how big is the footprint of a #conference like ENC/ISMAR 2025? I analyzed the data. 🧵👇
May 5, 2025 at 8:09 PM
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Great meeting so many inspiring colleagues and friends from the #NMR community at this year’s @enc-conference.org in Asilomar! I rarely travel to the US—trying to keep my carbon footprint low. But how big is the footprint of a #conference like ENC/ISMAR 2025? I analyzed the data. 🧵👇
Great meeting so many inspiring colleagues and friends from the #NMR community at this year’s @enc-conference.org in Asilomar! I rarely travel to the US—trying to keep my carbon footprint low. But how big is the footprint of a #conference like ENC/ISMAR 2025? I analyzed the data. 🧵👇
Amazing opportunity in the group of Prof. Nadinath Nillegoda. A great scientist and group leader!
WORK opportunity in Japan for a postdoctoral fellow for my friend Professor Nadinath Nillegoda’s Lab.
Please share and spread the word.
jobs.sciencecareers.org/job/672088/p...
Please share and spread the word.
jobs.sciencecareers.org/job/672088/p...
Postdoctoral Fellow for Professor Nadinath Nillegoda’s Lab - Tokyo (JP) job with Keio University Human Biology-Microbiome-Quantum Research Center (Bio2Q) | 672088
We are seeking a Postdoctoral Fellow with extensive experience in mouse and cell biology, molecular biology, cell/tissue imaging techniques.
jobs.sciencecareers.org
April 30, 2025 at 3:44 PM
Amazing opportunity in the group of Prof. Nadinath Nillegoda. A great scientist and group leader!
Check out our latest story on the cryoEM structure of the BAM-SurA holo insertase complex! Out in #ScienceAdvances (www.science.org/doi/full/10....)
April 17, 2025 at 7:29 PM
Check out our latest story on the cryoEM structure of the BAM-SurA holo insertase complex! Out in #ScienceAdvances (www.science.org/doi/full/10....)
Big week ahead for our lab! @annaleder.bsky.social presents at the 1.2 GHz inauguration in Zurich, and @masgu.bsky.social presents at @enc-conference.org (5:05pm PT) in Asilomar #ENCISMAR2025. They’ll share disruptive ideas on enzymology, molecular chaperones, LLPS, and ER biology. Don’t miss it!
April 6, 2025 at 12:29 AM
Big week ahead for our lab! @annaleder.bsky.social presents at the 1.2 GHz inauguration in Zurich, and @masgu.bsky.social presents at @enc-conference.org (5:05pm PT) in Asilomar #ENCISMAR2025. They’ll share disruptive ideas on enzymology, molecular chaperones, LLPS, and ER biology. Don’t miss it!