Philipp Jent
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phips81.bsky.social
Philipp Jent
@phips81.bsky.social
1.1K followers 1.2K following 7 posts
Infectious Diseases physician in Switzerland - family man - travel addict. Head of IPC @ Inselspital Bern university hospital @unibern.bsky.social - editor http://antibiotika.insel.ch
(Banner pic = view from my living room 🙃)
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Reposted by Philipp Jent
ryanmarino.bsky.social
They’re forming a CDC workgroup to decide which line on this graph looks better and their answer may surprise you
Global infant mortality rate with and without vaccines Infant mortality rates measure the share of newborns who die before reaching their first birthday. They are shown here as the actual observed change in the global rate (in blue), and a hypothetical scenario if vaccinations hadn't been rolled out (in red). While both lines decline, the gap between them continues to widen, resulting in an almost 50% difference at 2024. Data source: Shattock et al. (2024). Contribution of vaccination to improved child survival: modelling 50 years of the Expanded Programme on Immunization. CC BY
June 25, 2025 at 3:11 PM
phips81.bsky.social
Introducing CNS PCR panels does not automatically translate to shorter empiric antibiotic / antiviral treatment durations. We investigated the effect, and emphasize the need to educate prescribers on negative predictive performance of tests in order to generate trust. #idsky

doi.org/10.1093/ofid...
Introducing a New Polymerase Chain Reaction Panel–Based Cerebrospinal Fluid Evaluation for Encephalitis and Meningitis: Does It Influence Empiric Treatment Duration, Length of Hospital Stay, and Patho...
Abstract. We analyzed the impact of a diagnostic meningitis/encephalitis polymerase chain reaction panel. Introducing the test resulted in no significantly
doi.org
May 27, 2025 at 10:54 AM
Reposted by Philipp Jent
absteward.bsky.social
The most anticipated RCT in ID
🔥SNAP RCT🔥The largest RCT 2 date in SA bactermia
N:1341
Cefazolin Vs ASPs ((flu)cloxacillin) for MSSA bacteremia
Cefazolin is non-inferior (90d mortality)& less AKI than ASPs
A practice-changer RCT that must change the guidelines
#ESCMIDGlobal #IDSky
April 12, 2025 at 3:09 PM
Reposted by Philipp Jent
absteward.bsky.social
🆕️✨️The largest study to date of patients with Bacteroides spp. bacteremia
Metronidazole 500mg q12h dosing was not associated with worse outcomes compared to metronidazole 500mgq8h
Metro:500mgq12h must be used for most types of infections #idsky #medsky #EMIMCC
www.sciencedirect.com/science/arti...
Clinical outcomes of a twice daily metronidazole dosing strategy for Bacteroides bloodstream infections
The optimal metronidazole dose for the treatment of Bacteroides spp. has not been well-defined.This study was a multicenter, retrospective chart revie…
www.sciencedirect.com
December 10, 2024 at 7:56 PM
phips81.bsky.social
I hate pandemic fear mongering. However, this article in science is convincing that human-to-human transmission of bovine #h5n1 #influenza might be around the corner

www.science.org/doi/10.1126/...
A single mutation in bovine influenza H5N1 hemagglutinin switches specificity to human receptors
In 2024, several human infections with highly pathogenic clade 2.3.4.4b bovine influenza H5N1 viruses in the United States raised concerns about their capability for bovine-to-human or even human-to-h...
www.science.org
December 7, 2024 at 4:32 PM
Reposted by Philipp Jent
isaacbogoch.bsky.social
A good read on how Rwanda tackled their Marburg virus outbreak:

"What happened in Rwanda is captured by Louis Pasteur’s famous aphorism that 'chance favours the prepared mind' or, as in this instance, the prepared response system."

tinyurl.com/8aavau7j by Wilmot James et al.
#IDSky #MedSky
November 25, 2024 at 12:38 PM
phips81.bsky.social
Waking up to winterwonderland
November 22, 2024 at 6:40 AM
Reposted by Philipp Jent
absteward.bsky.social
🔥In Case You Missed It🔥
Our NEW WikiGuidelines
A stellar cast of auth🌟rs
54 members , 12 countries
The Third WikiGuidelines
After OM,IE
Guidelines for the Prevention Diagnosis,and Management of Urinary Tract Infections in Pediatrics & Adults #idsky
#JAMANetworkOpen
jamanetwork.com/journals/jam...
November 15, 2024 at 11:51 PM