Philip Ahern
@philipahern.bsky.social
Professional sceptic; never heard an uninteresting fact about T cells; I like microorganisms/microbiomes too.
Reposted by Philip Ahern
Populist Dems won. Moderate Dems won. We won in blue states. We won in purple states.
Maybe the take is that (a) people think Trump is out of control; and (b) people like Dems when we're taking a stand and fighting for what we believe in - as we have been for the last month.
Maybe the take is that (a) people think Trump is out of control; and (b) people like Dems when we're taking a stand and fighting for what we believe in - as we have been for the last month.
November 5, 2025 at 2:35 AM
Populist Dems won. Moderate Dems won. We won in blue states. We won in purple states.
Maybe the take is that (a) people think Trump is out of control; and (b) people like Dems when we're taking a stand and fighting for what we believe in - as we have been for the last month.
Maybe the take is that (a) people think Trump is out of control; and (b) people like Dems when we're taking a stand and fighting for what we believe in - as we have been for the last month.
Reposted by Philip Ahern
Happy to share new work from #theonlylabever, lead by the phenomenal @sltai.bsky.social - who developed a tool to study the biology of ILC3s, identifying their role in controlling CSF2-dependent myeloid cells. 🤗
@mucosalimmunol.bsky.social @societymucosalimm.bsky.social
OA: doi.org/10.1016/j.mu...
@mucosalimmunol.bsky.social @societymucosalimm.bsky.social
OA: doi.org/10.1016/j.mu...
October 15, 2025 at 5:11 AM
Happy to share new work from #theonlylabever, lead by the phenomenal @sltai.bsky.social - who developed a tool to study the biology of ILC3s, identifying their role in controlling CSF2-dependent myeloid cells. 🤗
@mucosalimmunol.bsky.social @societymucosalimm.bsky.social
OA: doi.org/10.1016/j.mu...
@mucosalimmunol.bsky.social @societymucosalimm.bsky.social
OA: doi.org/10.1016/j.mu...
I've noted for a long time a desire among many to try & write particular people out of the narrative of the history of Treg research. This review, by the one person everyone agrees is pivotal, provides an accurate assessment for those who don't know the field:
www.annualreviews.org/content/jour...
www.annualreviews.org/content/jour...
Naturally Arising CD4+ Regulatory T Cells for Immunologic Self-Tolerance and Negative Control of Immune Responses
▪ Abstract Naturally occurring CD4+ regulatory T cells, the majority of which express CD25, are engaged in dominant control of self-reactive T cells, contributing to the maintenance of immunologic sel...
www.annualreviews.org
October 7, 2025 at 3:04 PM
I've noted for a long time a desire among many to try & write particular people out of the narrative of the history of Treg research. This review, by the one person everyone agrees is pivotal, provides an accurate assessment for those who don't know the field:
www.annualreviews.org/content/jour...
www.annualreviews.org/content/jour...
Séamus Heaney was also uncontactable as he was sailing when he won for literature in '95
October 7, 2025 at 3:00 PM
Séamus Heaney was also uncontactable as he was sailing when he won for literature in '95
Anyone have any expertise/experience with interrogating SNP/InDel in a mouse genome using a reference genome. We have an alignment and are using Integrated Genomics Viewer, but are having trouble figuring some stuff out.
October 2, 2025 at 1:31 PM
Anyone have any expertise/experience with interrogating SNP/InDel in a mouse genome using a reference genome. We have an alignment and are using Integrated Genomics Viewer, but are having trouble figuring some stuff out.
Reposted by Philip Ahern
With deep gratitude, we thank Dr. Marc Jenkins for his decades of leadership, mentorship, and dedication to the Center for Immunology. The foundation he built will guide and inspire us for years to come.
August 25, 2025 at 12:06 PM
With deep gratitude, we thank Dr. Marc Jenkins for his decades of leadership, mentorship, and dedication to the Center for Immunology. The foundation he built will guide and inspire us for years to come.
Reposted by Philip Ahern
Gianna Hammer & I are thrilled to co-Chair the 64th @midwinter-immun.bsky.social Conference of Immunologists Jan. 24-27, 2026. Join us & an amazing lineup of speakers including Carla Rothlin as Dan Campbell memorial lecturer for some exciting science in lovely Asilomar, CA!
www.midwconfimmunol.org
www.midwconfimmunol.org
Midwinter Conference of Immunologists
The Midwinter Conference of Immunologists was founded in 1961 by a small group of Immunologists, among them Drs. Dan Campbell and Ray Owen. The goal of the Midwinter Conference is to provide a forum w...
www.midwconfimmunol.org
August 25, 2025 at 5:01 PM
Gianna Hammer & I are thrilled to co-Chair the 64th @midwinter-immun.bsky.social Conference of Immunologists Jan. 24-27, 2026. Join us & an amazing lineup of speakers including Carla Rothlin as Dan Campbell memorial lecturer for some exciting science in lovely Asilomar, CA!
www.midwconfimmunol.org
www.midwconfimmunol.org
Reposted by Philip Ahern
Ugh. So many businesses thrive only by amplifying insecurities and making us feel inadequate: Not good enough, not beautiful enough, not clean enough, not rich enough, not thin enough, not popular enough, not tech savvy enough. EFF THAT. Don’t buy what they’re selling. You’re wonderful as you are.
August 17, 2025 at 12:00 AM
Ugh. So many businesses thrive only by amplifying insecurities and making us feel inadequate: Not good enough, not beautiful enough, not clean enough, not rich enough, not thin enough, not popular enough, not tech savvy enough. EFF THAT. Don’t buy what they’re selling. You’re wonderful as you are.
Reposted by Philip Ahern
Studying ecoimmunology? 🌍🧬
Submit your work to Discovery Immunology’s new Ecoimmunology Special Collection, exploring how ecological factors shape immune responses in humans & animals.
📢 Editors: Dr Iris Mair & Prof Kathryn Else
🔗 https://bit.ly/4lZX3NM
##Ecoimmunology #Immunology
Submit your work to Discovery Immunology’s new Ecoimmunology Special Collection, exploring how ecological factors shape immune responses in humans & animals.
📢 Editors: Dr Iris Mair & Prof Kathryn Else
🔗 https://bit.ly/4lZX3NM
##Ecoimmunology #Immunology
August 2, 2025 at 12:45 PM
Studying ecoimmunology? 🌍🧬
Submit your work to Discovery Immunology’s new Ecoimmunology Special Collection, exploring how ecological factors shape immune responses in humans & animals.
📢 Editors: Dr Iris Mair & Prof Kathryn Else
🔗 https://bit.ly/4lZX3NM
##Ecoimmunology #Immunology
Submit your work to Discovery Immunology’s new Ecoimmunology Special Collection, exploring how ecological factors shape immune responses in humans & animals.
📢 Editors: Dr Iris Mair & Prof Kathryn Else
🔗 https://bit.ly/4lZX3NM
##Ecoimmunology #Immunology
Does anyone have any recommendations for a company/service that can sequence a mouse genome (B6 background) and provide analysis to a reference genome?
July 29, 2025 at 3:38 PM
Does anyone have any recommendations for a company/service that can sequence a mouse genome (B6 background) and provide analysis to a reference genome?
Reposted by Philip Ahern
🐭 How does microbial exposure shape mouse model outcomes?
A new Discovery Immunology study compares naturalization methods - co-housing, feralization, or both, and reveals distinct effects on gut immunity and microbiota.
🔗 https://bit.ly/44md5LQ
##Microbiome #Immunology
A new Discovery Immunology study compares naturalization methods - co-housing, feralization, or both, and reveals distinct effects on gut immunity and microbiota.
🔗 https://bit.ly/44md5LQ
##Microbiome #Immunology
July 17, 2025 at 11:50 AM
🐭 How does microbial exposure shape mouse model outcomes?
A new Discovery Immunology study compares naturalization methods - co-housing, feralization, or both, and reveals distinct effects on gut immunity and microbiota.
🔗 https://bit.ly/44md5LQ
##Microbiome #Immunology
A new Discovery Immunology study compares naturalization methods - co-housing, feralization, or both, and reveals distinct effects on gut immunity and microbiota.
🔗 https://bit.ly/44md5LQ
##Microbiome #Immunology
Reposted by Philip Ahern
Super excited to announce that MRC has funded a new Centre of Research Excellence in Exposome Immunology. Working together, Manchester and Oxford are going to tackle a major challenge of our times. For those who wonder what the Exposome is - see yesterday's posts! www.ukri.org/news/centre-...
Centre to study how exposome causes chronic inflammatory disease
A new Medical Research Council (MRC) centre will investigate how the environment interacts with our immune system to trigger chronic inflammatory diseases.
www.ukri.org
July 16, 2025 at 10:56 AM
Super excited to announce that MRC has funded a new Centre of Research Excellence in Exposome Immunology. Working together, Manchester and Oxford are going to tackle a major challenge of our times. For those who wonder what the Exposome is - see yesterday's posts! www.ukri.org/news/centre-...
Reposted by Philip Ahern
Writing a paper?
Join us tomorrow at 12:00 BST for a free webinar with OUP Publisher Rachel Moriarty & our very own EIC Simon Milling.
Essential tips on journal selection, peer review, and maximising impact.
Register here: https://bit.ly/44ARC1p
Join us tomorrow at 12:00 BST for a free webinar with OUP Publisher Rachel Moriarty & our very own EIC Simon Milling.
Essential tips on journal selection, peer review, and maximising impact.
Register here: https://bit.ly/44ARC1p
July 16, 2025 at 11:05 AM
Writing a paper?
Join us tomorrow at 12:00 BST for a free webinar with OUP Publisher Rachel Moriarty & our very own EIC Simon Milling.
Essential tips on journal selection, peer review, and maximising impact.
Register here: https://bit.ly/44ARC1p
Join us tomorrow at 12:00 BST for a free webinar with OUP Publisher Rachel Moriarty & our very own EIC Simon Milling.
Essential tips on journal selection, peer review, and maximising impact.
Register here: https://bit.ly/44ARC1p
Great piece re how to tackle reproducibility/fraud in science. Like many things in life, policing is a blunt tool, we should tackle the underlying causes of these issues.
academic.oup.com/jimmunol/art...
academic.oup.com/jimmunol/art...
The negative impacts of “impact”
Recent articles in several scientific journals highlight the troubling upsurge in retractions and data manipulation impacting the integrity of peer-reviewe
academic.oup.com
June 30, 2025 at 2:08 PM
Great piece re how to tackle reproducibility/fraud in science. Like many things in life, policing is a blunt tool, we should tackle the underlying causes of these issues.
academic.oup.com/jimmunol/art...
academic.oup.com/jimmunol/art...
Does anyone have DNA/ear biopsy from SJL (CD45.1) mice from Taconic or Charles River (originating from there, even if they've been in-house for a long time that's fine) that they can share? I don't have much reach here, would appreciate people sharing the post.
June 27, 2025 at 7:35 PM
Does anyone have DNA/ear biopsy from SJL (CD45.1) mice from Taconic or Charles River (originating from there, even if they've been in-house for a long time that's fine) that they can share? I don't have much reach here, would appreciate people sharing the post.
Reposted by Philip Ahern
New immunological discoveries deserve wide reach.
With read & publish deals, eligible authors can publish open access in Discovery Immunology for free! 🚀
Find out if you’re eligible here: bit.ly/4no9OTy
With read & publish deals, eligible authors can publish open access in Discovery Immunology for free! 🚀
Find out if you’re eligible here: bit.ly/4no9OTy
June 25, 2025 at 5:36 PM
New immunological discoveries deserve wide reach.
With read & publish deals, eligible authors can publish open access in Discovery Immunology for free! 🚀
Find out if you’re eligible here: bit.ly/4no9OTy
With read & publish deals, eligible authors can publish open access in Discovery Immunology for free! 🚀
Find out if you’re eligible here: bit.ly/4no9OTy
Reposted by Philip Ahern
Lawmakers in Congress should not be buying, trading, and owning individual stocks. Period.
It’s long past time to BAN Congressional stock trading.
It’s long past time to BAN Congressional stock trading.
June 13, 2025 at 9:13 PM
Lawmakers in Congress should not be buying, trading, and owning individual stocks. Period.
It’s long past time to BAN Congressional stock trading.
It’s long past time to BAN Congressional stock trading.
Reposted by Philip Ahern
📢 Final call! Submissions for the Re-discovering Myeloid Cells Special Collection close end of June 2025.
Share your latest insights into myeloid cell biology, function, and pathology. Don’t miss out!
🔗 https://bit.ly/43OULe9
Share your latest insights into myeloid cell biology, function, and pathology. Don’t miss out!
🔗 https://bit.ly/43OULe9
June 14, 2025 at 1:54 PM
📢 Final call! Submissions for the Re-discovering Myeloid Cells Special Collection close end of June 2025.
Share your latest insights into myeloid cell biology, function, and pathology. Don’t miss out!
🔗 https://bit.ly/43OULe9
Share your latest insights into myeloid cell biology, function, and pathology. Don’t miss out!
🔗 https://bit.ly/43OULe9
I thought this was really interesting. Somatic hypermutation can generate new specificities not present in the germline. Hard to quantify how prevalent such specificities are in the immune repertoire, but it would help prevent holes in the repertoire
www.cell.com/immunity/ful...
www.cell.com/immunity/ful...
Somatic hypermutation generates antibody specificities beyond the primary repertoire
Initial specificity is thought to be required for somatic hypermutation (SHM)-driven
antibody evolution. Zuo, Gautam, et al. demonstrate that non-cognate B cells can enter
germinal centers, undergo SH...
www.cell.com
June 13, 2025 at 1:00 AM
I thought this was really interesting. Somatic hypermutation can generate new specificities not present in the germline. Hard to quantify how prevalent such specificities are in the immune repertoire, but it would help prevent holes in the repertoire
www.cell.com/immunity/ful...
www.cell.com/immunity/ful...
Reposted by Philip Ahern
Excited to share that our study, on how T cells selectively sense foreign antigens with single-molecule sensitivity, is out! This work was led by the brilliant Will White, and done in collaboration with Jay Groves and David Baker @uwproteindesign.bsky.social
www.pnas.org/doi/10.1073/...
www.pnas.org/doi/10.1073/...
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
www.pnas.org
June 7, 2025 at 8:05 PM
Excited to share that our study, on how T cells selectively sense foreign antigens with single-molecule sensitivity, is out! This work was led by the brilliant Will White, and done in collaboration with Jay Groves and David Baker @uwproteindesign.bsky.social
www.pnas.org/doi/10.1073/...
www.pnas.org/doi/10.1073/...
Reposted by Philip Ahern
From bench to bedside, better models mean better arthritis therapies! 💡🧬
Explore this open access guide to standardizing murine arthritis scoring for clearer, comparable results.
Full article: https://bit.ly/4mEgigp
#InflammatoryArthritis #RheumatoidArthritis #AnimalModels #Immunology
Explore this open access guide to standardizing murine arthritis scoring for clearer, comparable results.
Full article: https://bit.ly/4mEgigp
#InflammatoryArthritis #RheumatoidArthritis #AnimalModels #Immunology
June 6, 2025 at 8:42 AM
From bench to bedside, better models mean better arthritis therapies! 💡🧬
Explore this open access guide to standardizing murine arthritis scoring for clearer, comparable results.
Full article: https://bit.ly/4mEgigp
#InflammatoryArthritis #RheumatoidArthritis #AnimalModels #Immunology
Explore this open access guide to standardizing murine arthritis scoring for clearer, comparable results.
Full article: https://bit.ly/4mEgigp
#InflammatoryArthritis #RheumatoidArthritis #AnimalModels #Immunology
Reposted by Philip Ahern
Discovery Immunology publishes sound science on novel immune mechanisms in humans and animals. We've published some great papers. Publishing here, with the British Society for Immunology @britsocimm.bsky.social also helps support the immunology community
@discovimmunol.bsky.social
@discovimmunol.bsky.social
Looking for a home for your immunology research? 🧬
Discovery Immunology publishes sound science on novel immune mechanisms in humans and animals - now welcoming veterinary immunology too! 🐾
🔗 Submit today: https://bit.ly/3WmPhl3
##Immunology #VeterinaryScience #OpenAccess
Discovery Immunology publishes sound science on novel immune mechanisms in humans and animals - now welcoming veterinary immunology too! 🐾
🔗 Submit today: https://bit.ly/3WmPhl3
##Immunology #VeterinaryScience #OpenAccess
June 3, 2025 at 7:57 AM
Discovery Immunology publishes sound science on novel immune mechanisms in humans and animals. We've published some great papers. Publishing here, with the British Society for Immunology @britsocimm.bsky.social also helps support the immunology community
@discovimmunol.bsky.social
@discovimmunol.bsky.social
Reposted by Philip Ahern
⏳ Final call! The Re-discovering Myeloid Cells collection closes for submissions at the end of this month.
Got research on monocytes, macrophages, or other myeloid cells? 🧬 Now’s the time to submit!
📢 Don’t miss out, submit today: https://bit.ly/4kLSs0L
#Immunology #MyeloidCells #Macrophages
Got research on monocytes, macrophages, or other myeloid cells? 🧬 Now’s the time to submit!
📢 Don’t miss out, submit today: https://bit.ly/4kLSs0L
#Immunology #MyeloidCells #Macrophages
June 3, 2025 at 9:00 AM
⏳ Final call! The Re-discovering Myeloid Cells collection closes for submissions at the end of this month.
Got research on monocytes, macrophages, or other myeloid cells? 🧬 Now’s the time to submit!
📢 Don’t miss out, submit today: https://bit.ly/4kLSs0L
#Immunology #MyeloidCells #Macrophages
Got research on monocytes, macrophages, or other myeloid cells? 🧬 Now’s the time to submit!
📢 Don’t miss out, submit today: https://bit.ly/4kLSs0L
#Immunology #MyeloidCells #Macrophages
Reposted by Philip Ahern
📢 Calling all immunology researchers! Submit your ground-breaking discoveries to Discovery Immunology - an Open Access journal by @britsocimm.bsky.social
Fast online publication, expert editorial board, and global visibility await! 🔬🌍
📝 Learn more: https://bit.ly/3TXQOgF
#Immunology
Fast online publication, expert editorial board, and global visibility await! 🔬🌍
📝 Learn more: https://bit.ly/3TXQOgF
#Immunology
May 29, 2025 at 3:39 PM
📢 Calling all immunology researchers! Submit your ground-breaking discoveries to Discovery Immunology - an Open Access journal by @britsocimm.bsky.social
Fast online publication, expert editorial board, and global visibility await! 🔬🌍
📝 Learn more: https://bit.ly/3TXQOgF
#Immunology
Fast online publication, expert editorial board, and global visibility await! 🔬🌍
📝 Learn more: https://bit.ly/3TXQOgF
#Immunology