Reposted by Matt Patton
Hmmm. Anyone think we’ll now get the punditry class to engage in weeks long debate about the need for the right to moderate and move more to the center to improve its electoral chances? …Anyone??
November 5, 2025 at 1:55 AM
Hmmm. Anyone think we’ll now get the punditry class to engage in weeks long debate about the need for the right to moderate and move more to the center to improve its electoral chances? …Anyone??
Reposted by Matt Patton
@bmj.com Please look at PubPeer comments on an article you published last week. pubpeer.com/publications...
I think your research integrity dept shld act swiftly on this one, given clinical significance.
I'm aware of even more evidence of problems so let me know if this is not sufficient.
I think your research integrity dept shld act swiftly on this one, given clinical significance.
I'm aware of even more evidence of problems so let me know if this is not sufficient.
PubPeer - Prevention of acute myocardial infarction induced heart fail...
There are comments on PubPeer for publication: Prevention of acute myocardial infarction induced heart failure by intracoronary infusion of mesenchymal stem cells: phase 3 randomised clinical trial (P...
pubpeer.com
November 2, 2025 at 3:02 PM
@bmj.com Please look at PubPeer comments on an article you published last week. pubpeer.com/publications...
I think your research integrity dept shld act swiftly on this one, given clinical significance.
I'm aware of even more evidence of problems so let me know if this is not sufficient.
I think your research integrity dept shld act swiftly on this one, given clinical significance.
I'm aware of even more evidence of problems so let me know if this is not sufficient.
Reposted by Matt Patton
hopeless autism study still up in J Pers Med despite
promise to retract it www.medpagetoday.com/opinion/seco...
This is how @mdpiopenaccess.bsky.social pollutes the literature with junk
promise to retract it www.medpagetoday.com/opinion/seco...
This is how @mdpiopenaccess.bsky.social pollutes the literature with junk
Opinion | A Journal Promised to Retract a Flawed Autism Study. It's Still Online.
Junk science leaves an indelible mark
www.medpagetoday.com
November 2, 2025 at 7:52 AM
hopeless autism study still up in J Pers Med despite
promise to retract it www.medpagetoday.com/opinion/seco...
This is how @mdpiopenaccess.bsky.social pollutes the literature with junk
promise to retract it www.medpagetoday.com/opinion/seco...
This is how @mdpiopenaccess.bsky.social pollutes the literature with junk
Reposted by Matt Patton
Eye-opening work on heterogeneity among depression scales. Also, I’m a pluralist and everything, but … do we need 27 youth depression scales? Why have researchers not updated and further developed them? What does this say about the state of our field?
Great to see our content analysis of 27 Chinese youth depression scales finally out!
Following @eikofried.bsky.social excellent work on depression scales, we included 27 scales and quantified the heterogeneity by analyzing data from 12,000 youth who completed 4 of them.
Comments are welcome!
Following @eikofried.bsky.social excellent work on depression scales, we included 27 scales and quantified the heterogeneity by analyzing data from 12,000 youth who completed 4 of them.
Comments are welcome!
November 1, 2025 at 6:15 AM
Eye-opening work on heterogeneity among depression scales. Also, I’m a pluralist and everything, but … do we need 27 youth depression scales? Why have researchers not updated and further developed them? What does this say about the state of our field?
Reposted by Matt Patton
How do you suppose the global homicide rate has changed over the last quarter century? (Hint: Another example of good things happening in our seemingly depressing world.) data.worldbank.org/indicator/VC...
World Bank Open Data
Free and open access to global development data
data.worldbank.org
October 24, 2025 at 1:46 PM
How do you suppose the global homicide rate has changed over the last quarter century? (Hint: Another example of good things happening in our seemingly depressing world.) data.worldbank.org/indicator/VC...
Reposted by Matt Patton
Another example of institutional investigations conducted in secret, without a public report, for 'privacy reasons'.
Investigation found UBC researcher fabricated data, gave spinal patients 'false hope.' The public was not told.
www.cbc.ca/news/canada/...
Investigation found UBC researcher fabricated data, gave spinal patients 'false hope.' The public was not told.
www.cbc.ca/news/canada/...
False hope, fabricated data: No public notice after UBC uncovered serious misconduct in medical study | CBC News
A celebrated Vancouver researcher used fabricated data and hid evidence of infected wounds to falsely claim his patented skin treatment could heal years-old bed sores in a matter of weeks, according t...
www.cbc.ca
October 24, 2025 at 6:40 PM
Another example of institutional investigations conducted in secret, without a public report, for 'privacy reasons'.
Investigation found UBC researcher fabricated data, gave spinal patients 'false hope.' The public was not told.
www.cbc.ca/news/canada/...
Investigation found UBC researcher fabricated data, gave spinal patients 'false hope.' The public was not told.
www.cbc.ca/news/canada/...
Reposted by Matt Patton
#OAweek Support diamond #openaccess scholar-controlled journals, such as those listed at freejournals.org.
October 23, 2025 at 4:19 AM
#OAweek Support diamond #openaccess scholar-controlled journals, such as those listed at freejournals.org.
Reposted by Matt Patton
New 6-month depression RCT in n=65, serial Ketamine infusions as adjunctive care vs active placebo midazolam.
Ketamine did not outperform primary nor any of the secondary efficacy, cognitive, economic, or quality-of-life outcomes.
🧪 #psychiary #PsychSciSky
jamanetwork.com/journals/jam...
Ketamine did not outperform primary nor any of the secondary efficacy, cognitive, economic, or quality-of-life outcomes.
🧪 #psychiary #PsychSciSky
jamanetwork.com/journals/jam...
Serial Ketamine Infusions for Depression
This randomized clinical trial evaluates outcomes following adjunctive ketamine infusions vs midazolam for depression.
jamanetwork.com
October 23, 2025 at 8:11 AM
New 6-month depression RCT in n=65, serial Ketamine infusions as adjunctive care vs active placebo midazolam.
Ketamine did not outperform primary nor any of the secondary efficacy, cognitive, economic, or quality-of-life outcomes.
🧪 #psychiary #PsychSciSky
jamanetwork.com/journals/jam...
Ketamine did not outperform primary nor any of the secondary efficacy, cognitive, economic, or quality-of-life outcomes.
🧪 #psychiary #PsychSciSky
jamanetwork.com/journals/jam...
Reposted by Matt Patton
In a new Editorial, Historical Biology promotes preregistration, Registered Reports, @pci-regreports.bsky.social and PCI-Paleonotology, and a three year plan to move to open and FAIR data standards.
A forward-looking approach by @drmarkyoung.bsky.social.
www.tandfonline.com/doi/pdf/10.1...
A forward-looking approach by @drmarkyoung.bsky.social.
www.tandfonline.com/doi/pdf/10.1...
www.tandfonline.com
October 17, 2025 at 1:05 PM
In a new Editorial, Historical Biology promotes preregistration, Registered Reports, @pci-regreports.bsky.social and PCI-Paleonotology, and a three year plan to move to open and FAIR data standards.
A forward-looking approach by @drmarkyoung.bsky.social.
www.tandfonline.com/doi/pdf/10.1...
A forward-looking approach by @drmarkyoung.bsky.social.
www.tandfonline.com/doi/pdf/10.1...
1/n
I'm considering writing a paper with many authors & wanted to ask for feedback from people who have experience (e.g., manylabs).
Assume a core team of 25 authors, and then 500 people who participate in a delphi study who I want to give authorship specifically for the participation in delphi
I'm considering writing a paper with many authors & wanted to ask for feedback from people who have experience (e.g., manylabs).
Assume a core team of 25 authors, and then 500 people who participate in a delphi study who I want to give authorship specifically for the participation in delphi
October 22, 2025 at 11:40 AM
Reposted by Matt Patton
Tune in to find out:
- how to go from hallucinated cat pictures to hallucinated proteins
- whether @jacobtref.bsky.social can do photosynthesis
- whether we can make tiny protein straws for tardigrades to drink from
- how to go from hallucinated cat pictures to hallucinated proteins
- whether @jacobtref.bsky.social can do photosynthesis
- whether we can make tiny protein straws for tardigrades to drink from
New episode of Hard Drugs!
What if you could design a protein never seen in nature?
Scientists are using new AI tools like RFDiffusion, AlphaFold & ProteinMPNN to hallucinate novel proteins to solve problems nature hasn't.
@jacobtref.bsky.social & I talk about the art of protein design 🧑🎨
What if you could design a protein never seen in nature?
Scientists are using new AI tools like RFDiffusion, AlphaFold & ProteinMPNN to hallucinate novel proteins to solve problems nature hasn't.
@jacobtref.bsky.social & I talk about the art of protein design 🧑🎨
The art of protein design with AI
YouTube video by Works in Progress
www.youtube.com
October 17, 2025 at 10:30 PM
Tune in to find out:
- how to go from hallucinated cat pictures to hallucinated proteins
- whether @jacobtref.bsky.social can do photosynthesis
- whether we can make tiny protein straws for tardigrades to drink from
- how to go from hallucinated cat pictures to hallucinated proteins
- whether @jacobtref.bsky.social can do photosynthesis
- whether we can make tiny protein straws for tardigrades to drink from
Reposted by Matt Patton
New episode of Hard Drugs!
What if you could design a protein never seen in nature?
Scientists are using new AI tools like RFDiffusion, AlphaFold & ProteinMPNN to hallucinate novel proteins to solve problems nature hasn't.
@jacobtref.bsky.social & I talk about the art of protein design 🧑🎨
What if you could design a protein never seen in nature?
Scientists are using new AI tools like RFDiffusion, AlphaFold & ProteinMPNN to hallucinate novel proteins to solve problems nature hasn't.
@jacobtref.bsky.social & I talk about the art of protein design 🧑🎨
The art of protein design with AI
YouTube video by Works in Progress
www.youtube.com
October 15, 2025 at 3:08 PM
New episode of Hard Drugs!
What if you could design a protein never seen in nature?
Scientists are using new AI tools like RFDiffusion, AlphaFold & ProteinMPNN to hallucinate novel proteins to solve problems nature hasn't.
@jacobtref.bsky.social & I talk about the art of protein design 🧑🎨
What if you could design a protein never seen in nature?
Scientists are using new AI tools like RFDiffusion, AlphaFold & ProteinMPNN to hallucinate novel proteins to solve problems nature hasn't.
@jacobtref.bsky.social & I talk about the art of protein design 🧑🎨
Reposted by Matt Patton
In 2018, Charles Murray challenged me to a bet: "We will understand IQ genetically—I think most of the picture will have been filled in by 2025—there will still be blanks—but we’ll know basically what’s going on." It's now 2025, and I claim a win. I write about it in The Atlantic.
Your Genes Are Simply Not Enough to Explain How Smart You Are
Seven years ago, I took a bet with Charles Murray about whether we’d basically understand the genetics of intelligence by now.
www.theatlantic.com
October 13, 2025 at 1:33 PM
In 2018, Charles Murray challenged me to a bet: "We will understand IQ genetically—I think most of the picture will have been filled in by 2025—there will still be blanks—but we’ll know basically what’s going on." It's now 2025, and I claim a win. I write about it in The Atlantic.
Reposted by Matt Patton
New post!
• Transplants could be safer, without needing immunosuppressives
• AI models and a LOT of filtering created a new antibiotic
• Paper mills are rising
• A long acting antiviral for flu?
and more.
I've written another round up of news in biotech and medicine with @nikomccarty.bsky.social
• Transplants could be safer, without needing immunosuppressives
• AI models and a LOT of filtering created a new antibiotic
• Paper mills are rising
• A long acting antiviral for flu?
and more.
I've written another round up of news in biotech and medicine with @nikomccarty.bsky.social
What's new in biology: October 2025
Safer transplants, new antibiotics, the rise of paper mills, long-term flu protection, slowing down ageing, and more.
www.worksinprogress.news
October 2, 2025 at 5:12 PM
New post!
• Transplants could be safer, without needing immunosuppressives
• AI models and a LOT of filtering created a new antibiotic
• Paper mills are rising
• A long acting antiviral for flu?
and more.
I've written another round up of news in biotech and medicine with @nikomccarty.bsky.social
• Transplants could be safer, without needing immunosuppressives
• AI models and a LOT of filtering created a new antibiotic
• Paper mills are rising
• A long acting antiviral for flu?
and more.
I've written another round up of news in biotech and medicine with @nikomccarty.bsky.social
Reposted by Matt Patton
Excellent detailed intro paper on open scholarship in clinical psychology by some of my favourite authors on the topic, including @drlynam.bsky.social @dsbarra.bsky.social @jnfrltackett.bsky.social @aidangcw.bsky.social @jdmiller.bsky.social and others. Perfect paper to turn into an intro lecture!
The Open Science Movement and Clinical Psychology Training: Rigorous Science is Transparent Science: https://osf.io/s46wd
October 2, 2025 at 6:59 PM
Excellent detailed intro paper on open scholarship in clinical psychology by some of my favourite authors on the topic, including @drlynam.bsky.social @dsbarra.bsky.social @jnfrltackett.bsky.social @aidangcw.bsky.social @jdmiller.bsky.social and others. Perfect paper to turn into an intro lecture!
Reposted by Matt Patton
Reposted by Matt Patton
So a spurious correlation from an observational study is “gold standard science”, but testing vaccines in multiple RCTs with over 30,000 participants each is not?
September 23, 2025 at 2:01 PM
So a spurious correlation from an observational study is “gold standard science”, but testing vaccines in multiple RCTs with over 30,000 participants each is not?
Reposted by Matt Patton
Your regular reminder that measles vaccines are the most lifesaving childhood vaccine in the schedule, and save over a million lives globally per year.
ourworldindata.org/measles-vacc...
ourworldindata.org/measles-vacc...
Measles vaccines save millions of lives each year
Measles once killed millions every year. Vaccines changed this, preventing disease, long-term immune damage, and deadly outbreaks.
ourworldindata.org
September 18, 2025 at 10:09 PM
Your regular reminder that measles vaccines are the most lifesaving childhood vaccine in the schedule, and save over a million lives globally per year.
ourworldindata.org/measles-vacc...
ourworldindata.org/measles-vacc...
Reposted by Matt Patton
New podcast episode of HARD DRUGS!
A hundred years ago, insulin was scraped from pig pancreases.
Today, it’s made by bacteria in giant tanks.
In this episode, we cover 100 years of insulin … in 15 minutes!
A hundred years ago, insulin was scraped from pig pancreases.
Today, it’s made by bacteria in giant tanks.
In this episode, we cover 100 years of insulin … in 15 minutes!
100 years of insulin in 15 minutes
open.spotify.com
September 16, 2025 at 5:51 PM
New podcast episode of HARD DRUGS!
A hundred years ago, insulin was scraped from pig pancreases.
Today, it’s made by bacteria in giant tanks.
In this episode, we cover 100 years of insulin … in 15 minutes!
A hundred years ago, insulin was scraped from pig pancreases.
Today, it’s made by bacteria in giant tanks.
In this episode, we cover 100 years of insulin … in 15 minutes!
Reposted by Matt Patton
89 of my journal articles were used to train Meta’s AI. You can alert the lawyers handling the class action suit if your intellectual works were used as well at www.anthropiccopyrightsettlement.com.
September 8, 2025 at 1:15 PM
89 of my journal articles were used to train Meta’s AI. You can alert the lawyers handling the class action suit if your intellectual works were used as well at www.anthropiccopyrightsettlement.com.
Reposted by Matt Patton
Pleased to learn that my department will be changing the name of the "Dissertation Defense" to the "Dissertation War"
September 5, 2025 at 12:15 PM
Pleased to learn that my department will be changing the name of the "Dissertation Defense" to the "Dissertation War"
Reposted by Matt Patton
#metascience Do you know Turkish? Please have a look at this draft Turkish translation of CRediT and let us know if you have any comments/ possible disagreements contributorshipcollaboration.github.io/projects/tra... Thank you!
Turkish translation of CRediT
Turkish English Kavramsallaştırma Conceptualization Fikirler; araştırmanın genel hedef ve amaçlarının belirlenmesi ya da geliştirilmesi. Ideas; formulation or evolution of overarching research goals a...
contributorshipcollaboration.github.io
September 4, 2025 at 2:46 PM
#metascience Do you know Turkish? Please have a look at this draft Turkish translation of CRediT and let us know if you have any comments/ possible disagreements contributorshipcollaboration.github.io/projects/tra... Thank you!
Reposted by Matt Patton
NEW EPISODE of HARD DRUGS!
“5 hours is too long!” some of you said after our first episode. So our second episode is 20 minutes 🤭
@jacobtref.bsky.social and I explore the world of proteins: how proteins fold into complex shapes, why complexity matters, how crowded and dynamic a cell really is.
“5 hours is too long!” some of you said after our first episode. So our second episode is 20 minutes 🤭
@jacobtref.bsky.social and I explore the world of proteins: how proteins fold into complex shapes, why complexity matters, how crowded and dynamic a cell really is.
Proteins: Weird blobs that do important things
open.spotify.com
September 3, 2025 at 4:20 PM
NEW EPISODE of HARD DRUGS!
“5 hours is too long!” some of you said after our first episode. So our second episode is 20 minutes 🤭
@jacobtref.bsky.social and I explore the world of proteins: how proteins fold into complex shapes, why complexity matters, how crowded and dynamic a cell really is.
“5 hours is too long!” some of you said after our first episode. So our second episode is 20 minutes 🤭
@jacobtref.bsky.social and I explore the world of proteins: how proteins fold into complex shapes, why complexity matters, how crowded and dynamic a cell really is.