Patrick Pla
@patrickpla.bsky.social
Developmental biology, stem cells at Paris-Saclay Institute of Neuroscience https://neuropsi.cnrs.fr/en/homepage/
On-line textbook (French) https://bcgdevelop.fr/
Also historical fantasy author (French)
https://chroniqueurdelatour.wordpress.com/a-propos
On-line textbook (French) https://bcgdevelop.fr/
Also historical fantasy author (French)
https://chroniqueurdelatour.wordpress.com/a-propos
Pinned
Patrick Pla
@patrickpla.bsky.social
· Nov 10
Neuroinflammation as a cause of differential Müller cell regenerative responses to retinal injury
The neuroinflammatory microenvironment is pivotal in triggering retinal regeneration.
www.science.org
Hello Bluesky ! Happy to be there ! Here you can find our last article. How inflammation influences regenerative retinal capacities in #Xenopus at different stages and in the #mouse : www.science.org/doi/10.1126/...
Very interesting talk by Pradeep Das about stiffness of meristemal stem cells in Arabidopsis (nice to see some plants at this meeting !) #FSSCR2025
November 19, 2025 at 8:32 AM
Very interesting talk by Pradeep Das about stiffness of meristemal stem cells in Arabidopsis (nice to see some plants at this meeting !) #FSSCR2025
Beautiful and very clear talk by @maitrejl.bsky.social on the key role of surface tension increase during compaction of human embryos. #FSSCR2025
November 18, 2025 at 2:36 PM
Beautiful and very clear talk by @maitrejl.bsky.social on the key role of surface tension increase during compaction of human embryos. #FSSCR2025
Excellent talk by Eve Gazave from @stemdevevo.bsky.social on regional differences in regeneration capabilities in Platynereis dumerilii. #FSSCR2025
November 18, 2025 at 9:24 AM
Excellent talk by Eve Gazave from @stemdevevo.bsky.social on regional differences in regeneration capabilities in Platynereis dumerilii. #FSSCR2025
Very nice talk by Silvia Torchio from @frelab.bsky.social showing how ROS levels control cell fate decisions in intestinal organoids #FSSCR2025
November 18, 2025 at 8:45 AM
Very nice talk by Silvia Torchio from @frelab.bsky.social showing how ROS levels control cell fate decisions in intestinal organoids #FSSCR2025
We started the day with a very interesting talk by @zaycha.bsky.social about mechanisms of adult neural stem cells coordination during pregnancy when specific new neurons are produced that are sensible to pup odours #FSSCR2025
November 18, 2025 at 8:31 AM
We started the day with a very interesting talk by @zaycha.bsky.social about mechanisms of adult neural stem cells coordination during pregnancy when specific new neurons are produced that are sensible to pup odours #FSSCR2025
Great talk by Céline Vallot from @institutcurie.bsky.social on mapping epigenomes in tumors at single-cell level during #FSSCR2025 meeting.
November 17, 2025 at 2:35 PM
Great talk by Céline Vallot from @institutcurie.bsky.social on mapping epigenomes in tumors at single-cell level during #FSSCR2025 meeting.
Hans Clevers, a pioneer of organoids, who is speaking now, is at the top of my predictions for the next Nobel Prize in Medicine #FSSCR2025
November 17, 2025 at 1:09 PM
Hans Clevers, a pioneer of organoids, who is speaking now, is at the top of my predictions for the next Nobel Prize in Medicine #FSSCR2025
Great thought-provoking talk of Maria Elena Torres-Padilla at #FSSCR2025 . Replication timing is a major and often overlooked epigenetic feature and is a determinant of cell potency and cell fate.
November 17, 2025 at 12:58 PM
Great thought-provoking talk of Maria Elena Torres-Padilla at #FSSCR2025 . Replication timing is a major and often overlooked epigenetic feature and is a determinant of cell potency and cell fate.
Reposted by Patrick Pla
The 7th #FSSCR Annual Meeting is starting today!
Welcome to all of you.
✨🔬 Exciting #StemCell science ahead!
Lyon, Nov 17–19, 2025
Use the hashtag #FSSCR2025 😍
Full program here 🫵
coms.events/fsscr25/en/d...
Welcome to all of you.
✨🔬 Exciting #StemCell science ahead!
Lyon, Nov 17–19, 2025
Use the hashtag #FSSCR2025 😍
Full program here 🫵
coms.events/fsscr25/en/d...
November 17, 2025 at 10:01 AM
The 7th #FSSCR Annual Meeting is starting today!
Welcome to all of you.
✨🔬 Exciting #StemCell science ahead!
Lyon, Nov 17–19, 2025
Use the hashtag #FSSCR2025 😍
Full program here 🫵
coms.events/fsscr25/en/d...
Welcome to all of you.
✨🔬 Exciting #StemCell science ahead!
Lyon, Nov 17–19, 2025
Use the hashtag #FSSCR2025 😍
Full program here 🫵
coms.events/fsscr25/en/d...
Now we are able to analyze a dinosaur's fossilized vomit. What a great time to be alive !
110 million years ago, a spinosaur's dinner got the best of it. Turns out the dino's fossilized vomit contained a new species of filter-feeding pterosaur!
I came across this paper a few days ago on social media and had a blast covering it for @science.org: www.science.org/content/arti...
I came across this paper a few days ago on social media and had a blast covering it for @science.org: www.science.org/content/arti...
Fossil vomit contains new species of pterosaur from Brazil
Filter-feeding flying reptile was likely devoured by a dinosaur during the early Cretaceous
www.science.org
November 13, 2025 at 9:47 PM
Now we are able to analyze a dinosaur's fossilized vomit. What a great time to be alive !
Le tome 6 de ma saga du Chroniqueur de la Tour "1533-1536 : Les liens du sang" paraitra dans une semaine. Dans ce livre, vous verrez François Ier, jusque là tolérant, basculer clairement dans le camp anti-protestant (1/3)
November 9, 2025 at 10:43 AM
Le tome 6 de ma saga du Chroniqueur de la Tour "1533-1536 : Les liens du sang" paraitra dans une semaine. Dans ce livre, vous verrez François Ier, jusque là tolérant, basculer clairement dans le camp anti-protestant (1/3)
Un petit compte-rendu de lecture du livre "Jurassic Park et les Sciences" qui peut être un beau cadeau de Noël pour les passionnés de science et de science-fiction : planet-vie.ens.fr/parutions/ju...
Jurassic Park et les sciences
Ce livre adopte une démarche multidisciplinaire pour mettre en perspective le scénario de science-fiction imaginé d’abord sous forme de roman par Michael Crichton avant sa célèbre adaptation cinématog...
planet-vie.ens.fr
November 3, 2025 at 2:04 PM
Un petit compte-rendu de lecture du livre "Jurassic Park et les Sciences" qui peut être un beau cadeau de Noël pour les passionnés de science et de science-fiction : planet-vie.ens.fr/parutions/ju...
At one point we should ask ourselves : "What the Müller glia cells do NOT do in the retina ?"
Our latest paper is out! While the circadian photoentrainment circuit has been extensively studied, the mechanisms regulating its development remain poorly understood. Here we show that retinal Müller glia play a key role in this process. Check it out! www.sciencedirect.com/science/arti...
Retinal glia regulate development of the circadian photoentrainment circuit
Circadian photoentrainment depends on intrinsically photosensitive retinal ganglion cells (ipRGCs), which convey environmental light information to th…
www.sciencedirect.com
October 29, 2025 at 2:44 PM
At one point we should ask ourselves : "What the Müller glia cells do NOT do in the retina ?"
Reposted by Patrick Pla
Un petit compte-rendu de ma visite à Bourg-en-Bresse de mai dernier, vu sous l'angle de la Renaissance comme d'habitude. Une ville pas forcément dans le top des sites touristiques mais qui vaut le détour : www.youtube.com/watch?v=vlCy...
La France sous François Ier (Episode 17) : Bourg-en-Bresse
YouTube video by Chroniqueur de la Tour
www.youtube.com
October 19, 2025 at 7:59 AM
Un petit compte-rendu de ma visite à Bourg-en-Bresse de mai dernier, vu sous l'angle de la Renaissance comme d'habitude. Une ville pas forcément dans le top des sites touristiques mais qui vaut le détour : www.youtube.com/watch?v=vlCy...
This is a sad news. His pioneer cloning experiment has always been the starting point of my teaching about developmental genes. www.magd.cam.ac.uk/news/profess...
Professor Sir John Gurdon FRS (1933-2025) | Magdalene College
Magdalene College is deeply saddened to announce the death of Professor Sir John Gurdon FRS, who served as Master of the College from 1995 to 2002.
www.magd.cam.ac.uk
October 7, 2025 at 5:40 PM
This is a sad news. His pioneer cloning experiment has always been the starting point of my teaching about developmental genes. www.magd.cam.ac.uk/news/profess...
Reposted by Patrick Pla
La science est formelle: le prochain gouvernement aura une durée négative
October 6, 2025 at 8:47 AM
La science est formelle: le prochain gouvernement aura une durée négative
Evidemment, Paris, Berlin et Vienne sont trois petites villes provinciales sans intérêt touristique. Pourquoi donc maintenir des trains qui permettent de les relier en un "temps éveillé" qui est faible ? (irony inside)
Trains de nuit : les lignes Paris-Berlin et Paris-Vienne, qui sont une alternative à l’aérien pour les personnes soucieuses de leur bilan carbone, sont sacrifiées pour des raisons budgétaires. Le succès était pourtant au rendez-vous.
Billet de Damien Dole :
Billet de Damien Dole :
Trains de nuit : le gouvernement renonce à une énième promesse écologique et oublie Jean Castex sur le quai
En 2020, le Premier ministre d’alors relançait les wagons-lits et ce sera sous sa direction que la SNCF mettra fin aux lignes Paris-Berlin /Vienne. Avec la fin d’une subvention, l’Etat abandonne au passage une alternative bas carbone.
www.liberation.fr
September 29, 2025 at 8:32 PM
Evidemment, Paris, Berlin et Vienne sont trois petites villes provinciales sans intérêt touristique. Pourquoi donc maintenir des trains qui permettent de les relier en un "temps éveillé" qui est faible ? (irony inside)
Solidaires avec nos amis du @mnhn.fr ! Courage !
Argh, c'est une sale année pour le MNHN.... entre ça et la cyberattaque...
Des cambrioleurs dérobent pour 600 000 euros de pépites d’or au Muséum national d’Histoire naturelle de Paris
Le précieux métal a été volé au sein de la galerie de géologie et de minéralogie de l’institution, dans la nuit du 15 au 16 septembre. Une «perte inestimable» pour la recherche et le patrimoine, déplo...
www.liberation.fr
September 17, 2025 at 9:03 AM
Solidaires avec nos amis du @mnhn.fr ! Courage !
Reposted by Patrick Pla
Mouse (Mus musculus) 🐭 is the powerhouse of mammalian genetics, essential for studying embryogenesis, organ development and gene function using transgenic technologies. 📸 Image by Zhong Hua also featured on the cover of Developmental Biology textbook (11th edition) #ModelMonday
September 15, 2025 at 7:53 PM
Mouse (Mus musculus) 🐭 is the powerhouse of mammalian genetics, essential for studying embryogenesis, organ development and gene function using transgenic technologies. 📸 Image by Zhong Hua also featured on the cover of Developmental Biology textbook (11th edition) #ModelMonday
Il y a exactement 10 ans, j'écrivais "L’odeur de chair brûlée se propagea à travers toute la baie", la première phrase de la saga du Chroniqueur de la Tour.
Que d'aventures et de rencontres depuis, à la fois pour les personnages et pour moi !
Que d'aventures et de rencontres depuis, à la fois pour les personnages et pour moi !
September 13, 2025 at 8:47 AM
Il y a exactement 10 ans, j'écrivais "L’odeur de chair brûlée se propagea à travers toute la baie", la première phrase de la saga du Chroniqueur de la Tour.
Que d'aventures et de rencontres depuis, à la fois pour les personnages et pour moi !
Que d'aventures et de rencontres depuis, à la fois pour les personnages et pour moi !
So cute 🥰 !
Who knew such cuteness was lurking in the eastern Pacific abyssal zone? This is the bumpy snailfish, Careproctus colliculi n. sp., described by Gerringer et al. in Ichs & Herps., sequences now in GenBank. doi.org/10.1643/i202...
September 9, 2025 at 8:05 PM
So cute 🥰 !
'It is not birth, marriage or death, but gastrulation which is truly the most important time in your life' (Lewis Wolpert). Happy to celebrate today the 50th anniversary of my gastrulation !
September 9, 2025 at 5:23 AM
'It is not birth, marriage or death, but gastrulation which is truly the most important time in your life' (Lewis Wolpert). Happy to celebrate today the 50th anniversary of my gastrulation !
Reposted by Patrick Pla
New findings in Science suggest that rodents owe much of their evolutionary success to their thumb-nail (the first digit, D1), an adaptation that gave them dexterous hands for cracking seeds and nuts.
Learn more in this week's issue: https://scim.ag/46caVho
Learn more in this week's issue: https://scim.ag/46caVho
September 4, 2025 at 6:05 PM
New findings in Science suggest that rodents owe much of their evolutionary success to their thumb-nail (the first digit, D1), an adaptation that gave them dexterous hands for cracking seeds and nuts.
Learn more in this week's issue: https://scim.ag/46caVho
Learn more in this week's issue: https://scim.ag/46caVho