Paige Arnold
paigearnold.bsky.social
Paige Arnold
@paigearnold.bsky.social
scientist in NYC📍postdoc in the Marraffini Lab at Rockefeller University | PhD in the Finley Lab at MSKCC | HHMI Hanna Gray Fellow
Reposted by Paige Arnold
🦠🧍‍♀️From bacterial to human immunity.

We report in @science.org the discovery of a human homolog of SIR2 antiphage proteins that participates in the TLR pathway of animal innate immunity.
Co-led wt @enzopoirier.bsky.social by D. Bonhomme and @hugovaysset.bsky.social

www.science.org/doi/10.1126/...
www.science.org
July 24, 2025 at 6:23 PM
Reposted by Paige Arnold
BREAKING: Scientists are staging a “science fair” in the lobby of a Congressional building to tell elected officials about the critical knowledge the US will lose because their research grants have been canceled.
July 8, 2025 at 3:31 PM
Reposted by Paige Arnold
A study from the #MarraffiniLab in @science.org shows that newly discovered weapons of bacterial self-defense take different approaches to achieving the same goal: preventing a virus from spreading through the bacterial population.

Learn more: bit.ly/4dvmBij
May 16, 2025 at 3:18 PM
Reposted by Paige Arnold
🦠🧫 @science.org Cat1 forms filament networks to degrade NAD+ during the type III CRISPR-Cas antiviral response | Science www.science.org/doi/10.1126/...
@christianfbaca.bsky.social @rockefelleruniv.bsky.social @hhmi.org @mskcancercenter.bsky.social
April 14, 2025 at 5:08 AM
Reposted by Paige Arnold
I'm excited to share our latest story from the
@lydiafinley.bsky.social lab, where we show that it's not just whether cells take up nutrients that matters, but how and where those metabolites are used. Out now in @naturemetabolism.bsky.social: rdcu.be/ejFTs 1/
Intracellular metabolic gradients dictate dependence on exogenous pyruvate
Nature Metabolism - Jackson et al. provide insight into how metabolic adaptations that accompany cell state transitions drive reliance on exogenous nutrient availability, focusing on pyruvate as a...
rdcu.be
April 28, 2025 at 2:28 PM
Reposted by Paige Arnold
✨🦟✨HOW DO MOSQUITOES HAVE SEX? ✨🦟✨

Join us for a wild journey into hidden female control, rapidly evolving stimulation devices, fierce species competition, and DEADLY MOSQUITOES!

www.biorxiv.org/content/10.1...
April 20, 2025 at 3:05 PM
I’m so excited for the start of the Aviram Lab!! Going to miss @naamaaviram.bsky.social in lab but at least she’s right across the street 🤞
March 4, 2025 at 10:56 AM
Reposted by Paige Arnold
Thrilled that my thesis work in @lydiafinley.bsky.social's lab is out in the world! We found that methotrexate targets a specific metabolic vulnerability in a particularly aggressive form of pediatric rhabdomyosarcoma. Thank you to everyone who contributed to this project over the years!
PAX3-FOXO1 drives targetable cell state-dependent metabolic vulnerabilities in rhabdomyosarcoma https://www.biorxiv.org/content/10.1101/2025.01.15.633227v1
January 20, 2025 at 4:45 PM
Reposted by Paige Arnold
Our latest preprint identifies (targetable!) metabolic programs intrinsic to different cancer cell states in rhabdomyosarcoma, out just in time for @katrinaparas.bsky.social's thesis defense tomorrow!
PAX3-FOXO1 drives targetable cell state-dependent metabolic vulnerabilities in rhabdomyosarcoma https://www.biorxiv.org/content/10.1101/2025.01.15.633227v1
January 20, 2025 at 4:20 PM
Reposted by Paige Arnold
HUGE congratulations to @paigearnold.bsky.social for being named a @hhmi.bsky.social Hanna Gray Fellow! A well-deserved recognition for all of your accomplishments and promise: I can't wait to see what you do next!!
New to 🦋 but beyond thrilled to share that I’m joining the new cohort of @hhmi.bsky.social #HannaGrayFellows! 🎉 I’m so excited to connect with this incredible community of scientists. Many thanks to HHMI for this opportunity and my mentors @lydiafinley.bsky.social and Luciano Marraffini!
Today we're thrilled to announce our 2024 #HannaGrayFellows! Please join us in welcoming and celebrating these outstanding early career scientists!
January 8, 2025 at 7:26 PM
New to 🦋 but beyond thrilled to share that I’m joining the new cohort of @hhmi.bsky.social #HannaGrayFellows! 🎉 I’m so excited to connect with this incredible community of scientists. Many thanks to HHMI for this opportunity and my mentors @lydiafinley.bsky.social and Luciano Marraffini!
Today we're thrilled to announce our 2024 #HannaGrayFellows! Please join us in welcoming and celebrating these outstanding early career scientists!
January 8, 2025 at 6:13 PM