Oguz Kanca
@okanca.bsky.social
Assistant professor at Baylor College of Medicine, Drosophila enthusiast, tackling the conserved genome one gene at a time
Reposted by Oguz Kanca
📣New from @okanca.bsky.social & co
📄De novo variants in CDKL1 and CDKL2 are associated with neurodevelopmental symptoms
🧬🪰🧠
📄De novo variants in CDKL1 and CDKL2 are associated with neurodevelopmental symptoms
🧬🪰🧠
De novo variants in CDKL1 and CDKL2 are associated with neurodevelopmental symptoms
This study identifies de novo variants in CDKL1 and CDKL2 in individuals with neurodevelopmental
symptoms and seizures. Functional analysis in fruit flies provides compelling evidence
that these varia...
www.cell.com
March 14, 2025 at 2:49 PM
📣New from @okanca.bsky.social & co
📄De novo variants in CDKL1 and CDKL2 are associated with neurodevelopmental symptoms
🧬🪰🧠
📄De novo variants in CDKL1 and CDKL2 are associated with neurodevelopmental symptoms
🧬🪰🧠
We are excited to share our latest paper published today linking specific variants in CDKL2 and CDKL1 to a novel neurodevelopmental disorder.
www.bcm.edu/news/new-cdk...
www.bcm.edu/news/new-cdk...
New CDKL genes linked to neurodevelopmental disorders
CDKL5, one of the five members of the CDKL family of genes, is important for proper neurodevelopment and associated with seizures. However, the role the...
www.bcm.edu
March 14, 2025 at 11:55 PM
We are excited to share our latest paper published today linking specific variants in CDKL2 and CDKL1 to a novel neurodevelopmental disorder.
www.bcm.edu/news/new-cdk...
www.bcm.edu/news/new-cdk...
Look what I made! 🦋 With help from Scholar Goggler scholargoggler.com made by @morinryan.bsky.social.
Thanks @axelvisel.bsky.social for inspiration.
Thanks @axelvisel.bsky.social for inspiration.
November 21, 2024 at 4:42 PM
Look what I made! 🦋 With help from Scholar Goggler scholargoggler.com made by @morinryan.bsky.social.
Thanks @axelvisel.bsky.social for inspiration.
Thanks @axelvisel.bsky.social for inspiration.
Reposted by Oguz Kanca
Hello Bsky folks - here is a paper that we published earlier this year - great collaboration with the Bellen lab, Hyung-lok Chung, @okanca.bsky.social and others. Have a look if you're interested in Cdk8/19, mitochondria, Parkinsonism and Drosophila!
Liao, J. Z., Chung, H. L., Shih, C., Wong, K. K. L., ...., Sew, K., Bellen, H. J., Verheyen, E. M. (2024). Cdk8/CDK19 promotes mitochondrial fission through Drp1 phosphorylation and can phenotypically suppress pink1 deficiency in Drosophila. Nat Commun, 15(1):3326 www.nature.com/articles/s41...
Cdk8/CDK19 promotes mitochondrial fission through Drp1 phosphorylation and can phenotypically suppress pink1 deficiency in Drosophila - Nature Communications
Mitochondrial fission, performed by Drp1, is carefully regulated, particularly in neurons. Here, the authors examine Drosophila Cdk8/CDK19 function in mitochondrial fission and uncover a role phosphor...
www.nature.com
November 20, 2024 at 5:51 AM
Hello Bsky folks - here is a paper that we published earlier this year - great collaboration with the Bellen lab, Hyung-lok Chung, @okanca.bsky.social and others. Have a look if you're interested in Cdk8/19, mitochondria, Parkinsonism and Drosophila!
Reposted by Oguz Kanca
All these awesome starter packs are a great way to find folks to invite to conferences or seminars! I've met so many new people in the last few days 🪰🐸🪱🐭🐠
Check out the Animal models of disease one I made!
go.bsky.app/MhUwjSx
Check out the Animal models of disease one I made!
go.bsky.app/MhUwjSx
November 16, 2024 at 5:12 PM
All these awesome starter packs are a great way to find folks to invite to conferences or seminars! I've met so many new people in the last few days 🪰🐸🪱🐭🐠
Check out the Animal models of disease one I made!
go.bsky.app/MhUwjSx
Check out the Animal models of disease one I made!
go.bsky.app/MhUwjSx
Reposted by Oguz Kanca
I thought we could use a Drosophila starter pack, please let me know if you’d like to be added. (I think there is also a more general insect list out there somewhere that i cant find rn..) go.bsky.app/JGggkH3
November 12, 2024 at 11:42 PM
I thought we could use a Drosophila starter pack, please let me know if you’d like to be added. (I think there is also a more general insect list out there somewhere that i cant find rn..) go.bsky.app/JGggkH3