Nick Gladman
@nicholasgladman.bsky.social
Plant science and sorghum. https://www.sorghumbase.org/. Molecular biology, genetics, and genomics. USDA-ARS Scientist out of Cold Spring Harbor Laboratory. Posts don't necessarily reflect the positions of the USDA. Also chess.
Pinned
Nick Gladman
@nicholasgladman.bsky.social
· Nov 15
Hi there! I want to show you a cool feature on SorghumBase.org, a permanently-funded genomic and genetic database for people who work in the globally important crop sorghum.
You can search for gene models that have germplasm with disruptive SNPs and quickly order them from seed repositories. 🧵
You can search for gene models that have germplasm with disruptive SNPs and quickly order them from seed repositories. 🧵
Another fun chess position from a practice game. White was already losing, but is now lost after bxc5. Black has a single superior move to win material and infiltrate into white's position. What is it and what's the follow up?
Nominating @rasmansa.bsky.social to solve.
Nominating @rasmansa.bsky.social to solve.
January 21, 2026 at 3:16 AM
Another fun chess position from a practice game. White was already losing, but is now lost after bxc5. Black has a single superior move to win material and infiltrate into white's position. What is it and what's the follow up?
Nominating @rasmansa.bsky.social to solve.
Nominating @rasmansa.bsky.social to solve.
Reposted by Nick Gladman
Preprints of pandemic potential - new historical piece from me on the history of bioRxiv/medRxiv, their role in the pandemic, and the way forward. 1/n journals.asm.org/doi/10.1128/...
January 12, 2026 at 2:33 PM
Preprints of pandemic potential - new historical piece from me on the history of bioRxiv/medRxiv, their role in the pandemic, and the way forward. 1/n journals.asm.org/doi/10.1128/...
Wait, am I the only person who takes conference notes in markdown format on Visual Studio Code?
January 10, 2026 at 5:31 PM
Wait, am I the only person who takes conference notes in markdown format on Visual Studio Code?
I'll be at PAG33 running a USDA database workshop! Come say hi if you're in San Diego. And be sure to check out our plant comparative genomics database: GramenePlants.
www.gramene.org
www.gramene.org
January 8, 2026 at 2:10 PM
I'll be at PAG33 running a USDA database workshop! Come say hi if you're in San Diego. And be sure to check out our plant comparative genomics database: GramenePlants.
www.gramene.org
www.gramene.org
More online chess during the holiday. White was in a worse position, but is now completely lost. What is the only correct move for black to win material?
January 3, 2026 at 1:01 AM
More online chess during the holiday. White was in a worse position, but is now completely lost. What is the only correct move for black to win material?
More tactics in my adventures to discover some new openings. Opponent misplayed, but I missed the mate in 8 (with best play from black)! What is the best move for white in this position and why?
December 31, 2025 at 3:13 AM
More tactics in my adventures to discover some new openings. Opponent misplayed, but I missed the mate in 8 (with best play from black)! What is the best move for white in this position and why?
Can you swindle this chess position for white in one of my old blitz games? I was way down until black blundered. Oh, and, like me, you only have 25 seconds to find the win.
December 29, 2025 at 2:49 AM
Can you swindle this chess position for white in one of my old blitz games? I was way down until black blundered. Oh, and, like me, you only have 25 seconds to find the win.
Reposted by Nick Gladman
I’m from Whoville, and I say kill the Grinch!
December 25, 2025 at 10:29 PM
I’m from Whoville, and I say kill the Grinch!
Reposted by Nick Gladman
White to play and win by force.
December 26, 2025 at 1:57 AM
White to play and win by force.
Merry Christmas, y'all.
December 26, 2025 at 12:55 AM
Merry Christmas, y'all.
I count myself blessed to have participated in Hanukkah celebrations with people I care about.
Also, I can't believe I never had latkes until this year. A superior potato dish!
Everything was delicious, but current ranking:
Applesauce > applesauce + sour cream > sour cream.
Also, I can't believe I never had latkes until this year. A superior potato dish!
Everything was delicious, but current ranking:
Applesauce > applesauce + sour cream > sour cream.
December 22, 2025 at 2:33 AM
I count myself blessed to have participated in Hanukkah celebrations with people I care about.
Also, I can't believe I never had latkes until this year. A superior potato dish!
Everything was delicious, but current ranking:
Applesauce > applesauce + sour cream > sour cream.
Also, I can't believe I never had latkes until this year. A superior potato dish!
Everything was delicious, but current ranking:
Applesauce > applesauce + sour cream > sour cream.
Reposted by Nick Gladman
absolutely losing it at my 14yo's biology homework
December 15, 2025 at 2:02 AM
absolutely losing it at my 14yo's biology homework
Reposted by Nick Gladman
the thing that really bothers me is my kid saying that he doesn't want to know the real answer because if he puts information down that wasn't what he was taught, it will be graded as incorrect.
December 15, 2025 at 3:06 AM
the thing that really bothers me is my kid saying that he doesn't want to know the real answer because if he puts information down that wasn't what he was taught, it will be graded as incorrect.
Ask your Home Depot representative if methyl groups are right for you.
It's a real issue. This guy fell into a whole pool of methyl groups
December 15, 2025 at 2:13 AM
Ask your Home Depot representative if methyl groups are right for you.
Wait, am I the only one who keeps all their baking recipes as individual markdown files and then stores them on a public GitHub repo?
December 14, 2025 at 8:04 PM
Wait, am I the only one who keeps all their baking recipes as individual markdown files and then stores them on a public GitHub repo?
Consuming media as a parent is more different than I even anticipated--and I expected a BIG shift. E.g., watching season 5 episode 1 of Stranger Things hits waaay harder than when I saw season 1 episode 1 when it premiered.
November 28, 2025 at 3:30 AM
Consuming media as a parent is more different than I even anticipated--and I expected a BIG shift. E.g., watching season 5 episode 1 of Stranger Things hits waaay harder than when I saw season 1 episode 1 when it premiered.
Just spending a Tuesday night trying to troubleshoot a cool new genomic R package...as anyone would.
November 26, 2025 at 2:09 AM
Just spending a Tuesday night trying to troubleshoot a cool new genomic R package...as anyone would.
Sports media has been working toward these poisonous outcomes for years, well before online gambling was legal. It started with talking about odds lines and culminating in the creation of their own betting platforms. The money was well worth the very obvious negative consequences that would result.
Some of this is as old as gambling itself.
But when you institutionalize a gambling culture, you get more of it.
$DKNG $PENN $MGM $CZR $FLUT
But when you institutionalize a gambling culture, you get more of it.
$DKNG $PENN $MGM $CZR $FLUT
Jesus Christ.
November 15, 2025 at 4:03 PM
Sports media has been working toward these poisonous outcomes for years, well before online gambling was legal. It started with talking about odds lines and culminating in the creation of their own betting platforms. The money was well worth the very obvious negative consequences that would result.
James Watson has died.
James Watson, Co-Discoverer of the Structure of DNA, Is Dead at 97
www.nytimes.com
November 7, 2025 at 8:15 PM
James Watson has died.
I ran across another nice attacking chess puzzle today. Really highlights the tandem lesson of an under-defended king and the coordination of a pawn storm supported by pieces.
White missed better defensive moves and now black to move and be crushing.
White missed better defensive moves and now black to move and be crushing.
November 7, 2025 at 6:45 PM
I ran across another nice attacking chess puzzle today. Really highlights the tandem lesson of an under-defended king and the coordination of a pawn storm supported by pieces.
White missed better defensive moves and now black to move and be crushing.
White missed better defensive moves and now black to move and be crushing.
Another fun chess puzzle I ran across tonight. This seems like an endgame blunder that I would make in time trouble; a fun little maneuver for black to be winning.
November 3, 2025 at 2:21 AM
Another fun chess puzzle I ran across tonight. This seems like an endgame blunder that I would make in time trouble; a fun little maneuver for black to be winning.
Reposted by Nick Gladman
Reposted by Nick Gladman
Few people outside North Carolina have heard of Paul Newby, the chief justice of the state’s Supreme Court.
But Newby has had a huge impact on America and his state. He’s done this with the goal of delivering what he’s called “biblical justice, equal justice, for all.”
THREAD 👇
But Newby has had a huge impact on America and his state. He’s done this with the goal of delivering what he’s called “biblical justice, equal justice, for all.”
THREAD 👇
October 30, 2025 at 12:54 PM
Few people outside North Carolina have heard of Paul Newby, the chief justice of the state’s Supreme Court.
But Newby has had a huge impact on America and his state. He’s done this with the goal of delivering what he’s called “biblical justice, equal justice, for all.”
THREAD 👇
But Newby has had a huge impact on America and his state. He’s done this with the goal of delivering what he’s called “biblical justice, equal justice, for all.”
THREAD 👇
Found this old post from the @uwmadison.bsky.social Genetics Department. I honestly think my interview session with Barry Ganetzky got me their grad program. I really enjoyed my time and experiences with Barry, whom I hope is enjoying his retirement in a warm, sunny place.
October 26, 2025 at 2:08 AM
Found this old post from the @uwmadison.bsky.social Genetics Department. I honestly think my interview session with Barry Ganetzky got me their grad program. I really enjoyed my time and experiences with Barry, whom I hope is enjoying his retirement in a warm, sunny place.