Gaurav Das
@neurodas.bsky.social
Scientist, Group leader, The Brain and Feeding Behavior Lab, NCCS, Pune. We study feeding, post-ingestive nutrient perception, interoception, and memories of past meals. Neurobiology and cell biology.
Reposted by Gaurav Das
Much of study of #brain–body interactions is focus on the #gut–brain axis.
The enteric nervous system is where a lot of this plays out, here a primer 👇
www.cell.com/current-biol...
The enteric nervous system is where a lot of this plays out, here a primer 👇
www.cell.com/current-biol...
The enteric nervous system
In this primer, David Linden and Keith Sharkey discuss the development and cellular
organization of the enteric nervous system, and its role in controlling gut motility
and immune and mucosal function...
www.cell.com
October 30, 2025 at 4:22 PM
Much of study of #brain–body interactions is focus on the #gut–brain axis.
The enteric nervous system is where a lot of this plays out, here a primer 👇
www.cell.com/current-biol...
The enteric nervous system is where a lot of this plays out, here a primer 👇
www.cell.com/current-biol...
Reposted by Gaurav Das
This great primer from our #brain–body special by @dulaclab.bsky.social explores the many ways in which the brain and the immune system interact in the diseased state.
🧠
www.cell.com/current-biol...
🧠
www.cell.com/current-biol...
Sickness and the brain
Zuri Sullivan and Catherine Dulac discuss the reciprocal communication between the
brain and the immune system in sickness behavior.
www.cell.com
October 30, 2025 at 4:15 PM
This great primer from our #brain–body special by @dulaclab.bsky.social explores the many ways in which the brain and the immune system interact in the diseased state.
🧠
www.cell.com/current-biol...
🧠
www.cell.com/current-biol...
Reposted by Gaurav Das
@senapati.bsky.social latest and greatest! Charly Treiber on board too. Over and out.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Visceral signaling of post-ingestive malaise directs memory updating in Drosophila
Consolidation is a time when labile memories transition to a stable form. Malaise learning in Drosophila reveals consolidation to also permit memory updating. Flies taught to associate one of two odor...
www.biorxiv.org
October 23, 2025 at 8:32 PM
@senapati.bsky.social latest and greatest! Charly Treiber on board too. Over and out.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Gaurav Das
doi.org/10.1126/scie...
This seems rad: overexpressing FruM in a set of proboscis-motorneuron-projecting neurons makes melanogaster males add food-sharing to their courtship repertoire.
It is fascinating to see evolutionary shifts in behavior be tied so concretely to shifts in brain development!
This seems rad: overexpressing FruM in a set of proboscis-motorneuron-projecting neurons makes melanogaster males add food-sharing to their courtship repertoire.
It is fascinating to see evolutionary shifts in behavior be tied so concretely to shifts in brain development!
Cross-species implementation of an innate courtship behavior by manipulation of the sex-determinant gene
In accepting a courting male, Drosophila subobscura females require nuptial gift giving in which a male gives regurgitated crop contents to her mouth to mouth. No similar behavior is found in D. melan...
doi.org
October 20, 2025 at 2:39 AM
doi.org/10.1126/scie...
This seems rad: overexpressing FruM in a set of proboscis-motorneuron-projecting neurons makes melanogaster males add food-sharing to their courtship repertoire.
It is fascinating to see evolutionary shifts in behavior be tied so concretely to shifts in brain development!
This seems rad: overexpressing FruM in a set of proboscis-motorneuron-projecting neurons makes melanogaster males add food-sharing to their courtship repertoire.
It is fascinating to see evolutionary shifts in behavior be tied so concretely to shifts in brain development!
This is a manuscript long time coming from our lab. Mainly Work of the first two authors, ably supported by the rest of us. Also a big shoutout to Meet Zandawala, our collaborator. We have presented this at so many forums over the last 3 years. Hope you all enjoy it. Thanks!
A gut-brain axis for aversive interoception drives innate and anticipatory emesis in Drosophila. https://www.biorxiv.org/content/10.1101/2025.10.01.679515v1
October 9, 2025 at 4:18 AM
This is a manuscript long time coming from our lab. Mainly Work of the first two authors, ably supported by the rest of us. Also a big shoutout to Meet Zandawala, our collaborator. We have presented this at so many forums over the last 3 years. Hope you all enjoy it. Thanks!
Reposted by Gaurav Das
Fungus on the brain. @deepanshund.bsky.social @aliciahidalgolab.bsky.social &co show that the #fungus Beauveria bassiana exploits the Toll-1 host response to activate the MyD88 inhibitor Sarm, enabling immune evasion and triggering #neurodegeneration in #Drosophila 🧪 @plosbiology.org plos.io/3EIxgZN
February 17, 2025 at 10:16 AM
Fungus on the brain. @deepanshund.bsky.social @aliciahidalgolab.bsky.social &co show that the #fungus Beauveria bassiana exploits the Toll-1 host response to activate the MyD88 inhibitor Sarm, enabling immune evasion and triggering #neurodegeneration in #Drosophila 🧪 @plosbiology.org plos.io/3EIxgZN
Reposted by Gaurav Das
Expert's Dilemma: the more specialized you become, the less open you are to creative solutions from other fields. But the more you explore other fields, the more you risk losing credibility in your home field.
Interdisciplinary work is still not really embraced by academia.
Interdisciplinary work is still not really embraced by academia.
January 5, 2025 at 4:46 PM
Expert's Dilemma: the more specialized you become, the less open you are to creative solutions from other fields. But the more you explore other fields, the more you risk losing credibility in your home field.
Interdisciplinary work is still not really embraced by academia.
Interdisciplinary work is still not really embraced by academia.
Reposted by Gaurav Das
“Velvet ants are among the most well-defended insects, wielding not just venom, but warning coloration and odor, an extremely tough exoskeleton and long stinger, and the ability to “scream” when provoked.”
#scicomm
#neuroskyence
#pain
#sensoryecology
www.sciencenews.org/article/velv...
🧪 🐝 🐙 🧠
#scicomm
#neuroskyence
#pain
#sensoryecology
www.sciencenews.org/article/velv...
🧪 🐝 🐙 🧠
Velvet ants have the Swiss Army knife of venoms
A velvet ant bite like “hot oil from the deep fryer” delivers an array of peptides that inflicts pain on insects and mammals alike.
www.sciencenews.org
January 6, 2025 at 10:22 PM
“Velvet ants are among the most well-defended insects, wielding not just venom, but warning coloration and odor, an extremely tough exoskeleton and long stinger, and the ability to “scream” when provoked.”
#scicomm
#neuroskyence
#pain
#sensoryecology
www.sciencenews.org/article/velv...
🧪 🐝 🐙 🧠
#scicomm
#neuroskyence
#pain
#sensoryecology
www.sciencenews.org/article/velv...
🧪 🐝 🐙 🧠
Reposted by Gaurav Das
We are pleased to report publication of the Drosophila circadian clock connectome in @naturecomms.bsky.social. Check out the final version for additional analyses not present in the preprint. @unrcabnr.bsky.social www.nature.com/articles/s41...
January 6, 2025 at 7:03 PM
We are pleased to report publication of the Drosophila circadian clock connectome in @naturecomms.bsky.social. Check out the final version for additional analyses not present in the preprint. @unrcabnr.bsky.social www.nature.com/articles/s41...
Reposted by Gaurav Das
Today in
@currentbiology.bsky.social: a Quick Guide to the wondrous and fascinating biology of the clonal raider ant: authors.elsevier.com/a/1kOXg3QW8S...
@currentbiology.bsky.social: a Quick Guide to the wondrous and fascinating biology of the clonal raider ant: authors.elsevier.com/a/1kOXg3QW8S...
January 6, 2025 at 5:27 PM
Today in
@currentbiology.bsky.social: a Quick Guide to the wondrous and fascinating biology of the clonal raider ant: authors.elsevier.com/a/1kOXg3QW8S...
@currentbiology.bsky.social: a Quick Guide to the wondrous and fascinating biology of the clonal raider ant: authors.elsevier.com/a/1kOXg3QW8S...
Now that I am back to work, remembering the year end travels. Shivamogga, Kolkata and Bishnupur.
January 5, 2025 at 2:03 PM
Now that I am back to work, remembering the year end travels. Shivamogga, Kolkata and Bishnupur.
Reposted by Gaurav Das
Someone shared this with me, and I think it's beautiful. That's what I wish for everyone I love and appreciate in this New Year 2025, that your life is filled with an abundance of real luxuries. ❤️
January 1, 2025 at 6:10 PM
Someone shared this with me, and I think it's beautiful. That's what I wish for everyone I love and appreciate in this New Year 2025, that your life is filled with an abundance of real luxuries. ❤️
Reposted by Gaurav Das
This study investigates the role of Caspar in regulating the number of primordial germ cells that form during Drosophila embryogenesis.
Caspar specifies primordial germ cell count and identity in Drosophila melanogaster
During Drosophila primordial germ cells (PGCs) specification, the centrosome and germplasm are subject to regulation, during the maternal zygotic transition, by Caspar/TER94-dependent degradative…
buff.ly
January 1, 2025 at 9:21 AM
This study investigates the role of Caspar in regulating the number of primordial germ cells that form during Drosophila embryogenesis.
Reposted by Gaurav Das
Effects of social isolation are conserved from flies to humans. Built a low cost robust, scalable Drosophila aggression & courtship evaluator. Used supervised Java-based machine learning. Specific dopaminergic neurons regulate aggression. Pavan Agrawal, Kasturba Medical College #EMBOneuropeptides
December 6, 2024 at 7:07 AM
Effects of social isolation are conserved from flies to humans. Built a low cost robust, scalable Drosophila aggression & courtship evaluator. Used supervised Java-based machine learning. Specific dopaminergic neurons regulate aggression. Pavan Agrawal, Kasturba Medical College #EMBOneuropeptides
Reposted by Gaurav Das
#Immunology by First release now @science.org
Identification of APCs in the gut that promote Treg differentiation and how tolerance to food antigens is influenced by helminth infection
https://buff.ly/3DjNQ1e
By Maria Canesso, @danmucida.bsky.social , @victora.bsky.social and colleagues.
Identification of APCs in the gut that promote Treg differentiation and how tolerance to food antigens is influenced by helminth infection
https://buff.ly/3DjNQ1e
By Maria Canesso, @danmucida.bsky.social , @victora.bsky.social and colleagues.
December 19, 2024 at 8:08 PM
#Immunology by First release now @science.org
Identification of APCs in the gut that promote Treg differentiation and how tolerance to food antigens is influenced by helminth infection
https://buff.ly/3DjNQ1e
By Maria Canesso, @danmucida.bsky.social , @victora.bsky.social and colleagues.
Identification of APCs in the gut that promote Treg differentiation and how tolerance to food antigens is influenced by helminth infection
https://buff.ly/3DjNQ1e
By Maria Canesso, @danmucida.bsky.social , @victora.bsky.social and colleagues.
Reposted by Gaurav Das
So sad to read this 😢
As someone working in 🇦🇷 for 10+ years I know that Argentine colleagues always had to face difficult and often unpredictable conditions. But the Milei government is dismantling Argentina's scientific system with unprecedented aggression - www.nature.com/articles/d41...
As someone working in 🇦🇷 for 10+ years I know that Argentine colleagues always had to face difficult and often unpredictable conditions. But the Milei government is dismantling Argentina's scientific system with unprecedented aggression - www.nature.com/articles/d41...
‘There will be nothing left’: researchers fear collapse of science in Argentina
One year into Javier Milei’s presidency, scientists are exiting the country in the face of big budget cuts.
www.nature.com
December 19, 2024 at 5:04 PM
So sad to read this 😢
As someone working in 🇦🇷 for 10+ years I know that Argentine colleagues always had to face difficult and often unpredictable conditions. But the Milei government is dismantling Argentina's scientific system with unprecedented aggression - www.nature.com/articles/d41...
As someone working in 🇦🇷 for 10+ years I know that Argentine colleagues always had to face difficult and often unpredictable conditions. But the Milei government is dismantling Argentina's scientific system with unprecedented aggression - www.nature.com/articles/d41...
Reposted by Gaurav Das
How are #phospholipids transferred within #mitochondria? A study in #Drosophila shows that SLMO transfers phosphatidylserine (PS) from the outer to the inner mitochondrial membrane, where it is converted into PE, so contributing to mitochondrial form & function 🧪 #PLOSBiology plos.io/4iHc9qg
December 18, 2024 at 2:17 PM
How are #phospholipids transferred within #mitochondria? A study in #Drosophila shows that SLMO transfers phosphatidylserine (PS) from the outer to the inner mitochondrial membrane, where it is converted into PE, so contributing to mitochondrial form & function 🧪 #PLOSBiology plos.io/4iHc9qg
A friend and an awesome mentor. Apply!
🎓 Looking for a new PhD student to investigate the neuronal and molecular basis of learning and memory in #Drosophila!
This is a competitive, but fully funded position. More info here: tinyurl.com/drosobrain 🧠 🪰
Deadline: 8th January 2025
#Neuroskyence
#Memory
#Neuroscience
#Dopamine
This is a competitive, but fully funded position. More info here: tinyurl.com/drosobrain 🧠 🪰
Deadline: 8th January 2025
#Neuroskyence
#Memory
#Neuroscience
#Dopamine
December 19, 2024 at 11:56 AM
A friend and an awesome mentor. Apply!
Reposted by Gaurav Das
🎓 Looking for a new PhD student to investigate the neuronal and molecular basis of learning and memory in #Drosophila!
This is a competitive, but fully funded position. More info here: tinyurl.com/drosobrain 🧠 🪰
Deadline: 8th January 2025
#Neuroskyence
#Memory
#Neuroscience
#Dopamine
This is a competitive, but fully funded position. More info here: tinyurl.com/drosobrain 🧠 🪰
Deadline: 8th January 2025
#Neuroskyence
#Memory
#Neuroscience
#Dopamine
December 18, 2024 at 5:58 PM
🎓 Looking for a new PhD student to investigate the neuronal and molecular basis of learning and memory in #Drosophila!
This is a competitive, but fully funded position. More info here: tinyurl.com/drosobrain 🧠 🪰
Deadline: 8th January 2025
#Neuroskyence
#Memory
#Neuroscience
#Dopamine
This is a competitive, but fully funded position. More info here: tinyurl.com/drosobrain 🧠 🪰
Deadline: 8th January 2025
#Neuroskyence
#Memory
#Neuroscience
#Dopamine
Reposted by Gaurav Das
Everyone is talking about #Ozempic #Wegovy which are agonists of the GLP-1 receptor. For more about this receptor and its physiological role, see the quickguide by Michael Krashes in our latest issue
www.cell.com/current-biol...
www.cell.com/current-biol...
Glucagon-like peptide-1 receptor
Michael Krashes discusses glucagon-like peptide-1 receptors, their physiological role
in glucose metabolism and the mode of action of their agonists that are used to treat
obesity and were later shown...
www.cell.com
December 3, 2024 at 7:38 PM
Everyone is talking about #Ozempic #Wegovy which are agonists of the GLP-1 receptor. For more about this receptor and its physiological role, see the quickguide by Michael Krashes in our latest issue
www.cell.com/current-biol...
www.cell.com/current-biol...