Paula Navarro
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navarropaula.bsky.social
Paula Navarro
@navarropaula.bsky.social
Cryo-electron tomography all the time. #teamtomo
Assistant Professor at DMF-UNIL,Switzerland
https://wp.unil.ch/navarrolab/
Pinned
🚨👉 Please check our recent work on bacterial cell division. In situ Cryo-ET reveals the cellular function of the penicillin binding protein 1b supported by AFM, live-cell imaging, in silico AlphaFold proteome screen and TIRFM. Hope you enjoy the read! #teamtomo #cryo-ET ❄️🔬🐎 big thanks to the team!
The aPBP-type cell wall synthase PBP1b plays a specialized role in fortifying the Escherichia coli division site against osmotic rupture https://www.biorxiv.org/content/10.1101/2025.04.02.646830v1
Reposted by Paula Navarro
Thrilled to share that the final piece of my PhD work is now on bioRxiv! biorxiv.org/content/10.1... With support from @nvidia and the @NSF, we used AlphaFold to screen 1.6M+ protein pairs, revealing thousands of potential novel PPIs. All data can be viewed at predictomes.org/hp
Proteome-wide in silico screening for human protein-protein interactions
Protein-protein interactions (PPIs) drive virtually all biological processes, yet most PPIs have not been identified and even more remain structurally unresolved. We developed a two-step computational...
biorxiv.org
November 12, 2025 at 9:26 PM
Reposted by Paula Navarro
And that’s a wrap on the Great Wall Symposium 2025!
Roll on 2027, venue to be confirmed shortly …
September 17, 2025 at 6:29 PM
Reposted by Paula Navarro
We are hiring a Postdoc in membrane protein cryo-EM at the University of Georgia. Looking for candidates with expertise in membrane protein purification and biochemistry. Fully funded for up to 5 years. Join us in Athens, GA. Apply: camilo.perez@uga.edu
August 21, 2025 at 2:26 PM
So happy to have contributed to this beautiful study led by PetrPelech! A combined theory–experiment effort based on our in situ cryo-ET data, revealing how stress-mediated growth shapes E. coli division site morphogenesis. #teamtomo 🌐 🦠🔬❄️🐎
👉📄 doi.org/10.1073/pnas...
Stress-mediated growth determines Escherichia coli division site morphogenesis | PNAS
In order to proliferate, bacteria must remodel their cell wall at the division site. The division process is driven by the enzymatic activity of pe...
doi.org
July 15, 2025 at 3:58 PM
Reposted by Paula Navarro
🚨New preprint!🚨 #teamtomo
We expanded Surface Morphometrics to quantify membrane thickness from cryo-ET—revealing local variation across organelles.

Led by the lab’s first grad student, @mmedina300kv.bsky.social (defending Monday! 🍾) w/ @attychang.bsky.social @hamid13r.bsky.social & @tomo.science
Surface morphometrics reveals local membrane thickness variation in organellar subcompartments https://www.biorxiv.org/content/10.1101/2025.04.30.651574v1
May 1, 2025 at 7:42 PM
Reposted by Paula Navarro
We are looking for a postdoctoral fellow to join us to explore telomerase regulation by histones. Please get in touch if this may interest you.
Excellent opportunity available for a motivated #postdoc to join @kellythd-nguyen.bsky.social’s group investigating the roles of histones in regulating telomerase using a multi-disciplinary approach.
More details: www.nature.com/naturecareer...
Apply by 04 MAY
#PostdocJobs #ScienceJobs
April 16, 2025 at 5:25 PM
Reposted by Paula Navarro
Join the Blokesch lab (@EPFL) as a postdoc in Molecular Microbiology 🤩
Study Vibrio cholerae defense systems (phage/plasmid) in a dynamic, collaborative environment in Lausanne close to Lake Geneva in 🇨🇭!
Please visit my lab's webpage for details about the position and how to formally apply.
April 25, 2025 at 4:15 PM
Reposted by Paula Navarro
After years parked at a Polara, I’m excited to share that my PhD work is finally out! We figured out why imaging at liquid helium temperatures wasn’t working—and how to fix it.
🔗 www.pnas.org/doi/10.1073/...
Reducing the effects of radiation damage in cryo-EM using liquid helium temperatures | PNAS
The physical limit in determining the atomic structure of biological molecules is radiation damage. In electron cryomicroscopy, there have been num...
www.pnas.org
April 23, 2025 at 4:23 AM
Reposted by Paula Navarro
Parmi les nouveaux #subsides de #recherche financés par le @snf-fns-ch.bsky.social 2️⃣3️⃣ projets de la #FBM (UNIL-CHUV-Unisanté) ont été retenus.

Découvrez les nouvelles et nouveaux #récipiendaireswww.unil.ch/news/1744125...
👏 Félicitations 👏

@unil.bsky.social #chuv #unisanté
Subsides de recherche financés par le FNS: nouvelles et nouveaux récipiendaires UNIL-CHUV-Unisanté
Parmi les nouveaux subsides de recherche financés par le FNS, 23 projets de la FBM (UNIL-CHUV-Unisanté) ont été retenus.
www.unil.ch
April 11, 2025 at 6:30 AM
Reposted by Paula Navarro
Our work on HIV-1 matrix, led by James Stacey and @dhrebik.bsky.social, is in this week's @nature.com. Extended explanatory video from @margotriggi.bsky.social.

www.nature.com/articles/s41...
April 4, 2025 at 1:03 PM
Reposted by Paula Navarro
The aPBP-type cell wall synthase PBP1b plays a specialized role in fortifying the Escherichia coli division site against osmotic rupture www.biorxiv.org/content/10.1101/2025.04.02.646830v1 #cryoem
April 3, 2025 at 7:10 AM
🚨👉 Please check our recent work on bacterial cell division. In situ Cryo-ET reveals the cellular function of the penicillin binding protein 1b supported by AFM, live-cell imaging, in silico AlphaFold proteome screen and TIRFM. Hope you enjoy the read! #teamtomo #cryo-ET ❄️🔬🐎 big thanks to the team!
The aPBP-type cell wall synthase PBP1b plays a specialized role in fortifying the Escherichia coli division site against osmotic rupture https://www.biorxiv.org/content/10.1101/2025.04.02.646830v1
April 3, 2025 at 9:08 AM
Double the grants, double the money, double the impact! Huge thanks to our amazing teams -proof that scientific power couples thrive in inclusive, diverse and open-minded institutions. And the real winner? Science, of course!🏆🔬Grateful beyond words! ❄️🐎 @dmf-unil.bsky.social @snsf-ch.bsky.social
April 1, 2025 at 10:35 AM
Reposted by Paula Navarro
Asgard archaea have actin - but what about microtubules? Where do they come from? 🧐 Our new paper www.cell.com/cell/fulltex... by @xujwet.bsky.social & @florianwollweber.bsky.social, in collaboration with the Schleper & Wieczorek labs, describes tiny Asgard microtubules! #TeamTomo #ArchaeaSky 1/6
March 21, 2025 at 3:16 PM
Reposted by Paula Navarro
WE GOT THE COVER!!!
In a new Science study, cryo–electron tomography captures the in-cell architecture of the mitochondrial respiratory chain, illuminating how the coordinated action of molecular machines drives life’s fundamental energy conversion.

Learn more in this week's issue: scim.ag/3FA3Ygq
March 20, 2025 at 7:16 PM
Hello bluesky community! Happy to be finally here ;)🐎
March 8, 2025 at 6:49 PM