Nature Protocols, Published online: 09 January 2026; doi:10.1038/s41596-025-01286-xThis protocol covers the acoustics-based separation of biological particles such as viruses and single extracellular vesicles from biofluids, including plasma and saliva, with high purity.

Nature Reviews Materials, Published online: 08 January 2026; doi:10.1038/s41578-025-00874-3Nanoprinting is a powerful fabrication strategy for scalable, high-resolution optical metasurfaces made from a diverse range of materials. This Review surveys recent advances in printing precision, throughput and reconfigurable materials, highlighting the promise of nanoprinting for next-generation flat-optics manufacturing and advanced photonic systems.

A material that can switch its appearance, cephalopod-style, could have future applications in robotics or display technology.

Researchers are targeting dormant tumour cells that might explain why some cancers reappear long after successful treatment.

This cross-journal collection will consider submissions of research articles that highlight advances in nanomedicine aimed at overcoming cancer treatment ...

A model quantifies the environmental footprint of wearable health-care electronics and identifies strategies to reduce their environmental toll.

Nature - A century ago, physics had its Darwinian moment — a change in perspective that was as consequential for the physical sciences as the theory of evolution by natural selection was for biology.

Nature Nanotechnology, Published online: 30 December 2025; doi:10.1038/s41565-025-02074-0A tandem catalytic strategy is developed to convert polystyrene waste into a spectrum of aromatic intermediates and subsequently into a single dominant product, toluene. This tandem design enhances product selectivity and minimizes downstream separation costs.

Nature Nanotechnology, Published online: 30 December 2025; doi:10.1038/s41565-025-02062-4Application of Zn metal batteries is limited by high water activity in their electrolytes. Now, an aqueous–hydrotrope hybrid electrolyte is proposed that minimizes the water activity by confining water molecules in a hydrophilic–hydrophobic solvation sheath. This approach increases the electrochemical stability window and operating temperature range.

Nature Nanotechnology, Published online: 30 December 2025; doi:10.1038/s41565-025-02072-2The multielectron CO2 reduction reaction in acid with molecular cobalt phthalocyanine catalysts is challenged by weak CO binding and competing CO2 and hydrogen adsorption. Now, a cationic, hydrophobic and aerophilic layer is shown to regulate the microenvironment around the cobalt catalytic centres, enabling 62% methanol Faradaic efficiency in strong acid.

Nature Nanotechnology, Published online: 30 December 2025; doi:10.1038/s41565-025-02053-5This Review presents a nanotechnology-enabled approach to the molecular design of biomolecular condensates from synthetic phase-separating building blocks, with applications in drug delivery, catalysis, cell-free protein factories, sensors and 3D bioprinting.

Nature Nanotechnology, Published online: 29 December 2025; doi:10.1038/s41565-025-02093-xTechnological developments in reproductive medicine, driven by the convergence of micro-robotics and nanosensors, along with decision-making aided by artificial intelligence, are enabling precise manipulation, gamete selection, embryo assessment and personalized treatment. These disruptive advances could lead to fully automated in vitro fertilization workflows. However, clinical implementation will need to address various technical, biological and ethical challenges to ensure safer and more effective fertility solutions.

Nature Nanotechnology, Published online: 29 December 2025; doi:10.1038/s41565-025-02083-zAn ultrasmall particle adjuvant therapy reprogrammes the tumour microenvironment of a resistant melanoma to a pro-inflammatory state, enhances antitumour immunity and synergizes with immune checkpoint inhibitors to prolong survival in murine models.

Nature Nanotechnology, Published online: 29 December 2025; doi:10.1038/s41565-025-02082-0A virus-mimicking micelle selectively delivers drugs to diseased chondrocytes in osteoarthritis, significantly alleviating disease progression in mouse and sheep models.

Nature Nanotechnology, Published online: 26 December 2025; doi:10.1038/s41565-025-02039-3This Review highlights fundamental optical phenomena that have been redefined at the nanoscale by anisotropic polaritons, including anomalous cases of refraction, reflection and focusing.

Nature Nanotechnology, Published online: 26 December 2025; doi:10.1038/s41565-025-02068-yExciton propagation in CrSBr is strongly influenced by magnetic properties, particularly peaking at the Néel temperature. Its transport is not governed by classical diffusion but rather by an interaction with the spin degree of freedom, specifically through a magnon–exciton drag effect.

Nature Nanotechnology, Published online: 26 December 2025; doi:10.1038/s41565-025-02064-2A biohybrid chiral hydrogel combining cell-membrane-coated nanoparticles with a D-chiral matrix reduces tumour stemness via biochemical and biophysical regulation, boosting radioimmunotherapy and preventing postoperative glioblastoma recurrence.

Nature Nanotechnology, Published online: 24 December 2025; doi:10.1038/s41565-025-02080-2Engineered carbon nanotube sensors enable the detection of intracranial tumours in blood, identify low-abundance biomarkers and amplify cancer detection by capturing secreted factors from the entire tumour ecosystem for early-stage disease diagnosis.

Nature Nanotechnology, Published online: 23 December 2025; doi:10.1038/s41565-025-02098-6Companies are scaling up advanced recycling technologies that could expand capacity, but experts think policies that level the economic playing field are currently the bottleneck.

Nature Nanotechnology, Published online: 23 December 2025; doi:10.1038/s41565-025-02070-4A hand-rotation-powered, nanomaterial-enabled disinfection system generates reactive oxygen species that rapidly disinfect a wide range of pathogens by leveraging mechanically induced interfacial electric fields. This electricity-free operation, having high efficiency, safety and long-lasting microbial protection, offers a robust, portable solution for clean-water access in disaster situations and in environments where the electricity grid is unavailable.

Nature Nanotechnology, Published online: 23 December 2025; doi:10.1038/s41565-025-02094-wBy harnessing the hyperfine coupling to the hydrogen nuclear spin and a nearby 29Si nuclear spin, a T-centre in silicon forms a combined quantum register and a spin–photon interface that is operational in the telecommunications original band.

Nature Nanotechnology, Published online: 23 December 2025; doi:10.1038/s41565-025-02071-3A peptide-based PD-L1-targeted nanorobot disrupts cancer cell membranes via pH-responsive fibril formation, and enhances T cell infiltration and immune activation, inducing a potent anticancer response in animal models of colorectal cancer.

Nature Nanotechnology, Published online: 23 December 2025; doi:10.1038/s41565-025-02092-yA two-step doping strategy for preparing Nb-doped Ni-rich positive electrode active materials forms nanosized grains and enables reversible multiphase transitions, improving lithium-ion transport and high-power performance of Li-based batteries.