Nature Reviews Bioengineering, Published online: 17 November 2025; doi:10.1038/s44222-025-00386-3Artificial intelligence might reshape the approach to science, from generating concepts and hypotheses to designing experiments, analysing data and publishing findings. However, it might also introduce risks around data integrity, reproducibility, accountability and bias. Here we provide practical guidance on how to responsibly integrate artificial intelligence into the research pipeline.

Aqueous-hydrotrope hybrid liquid electrolyte solutions enable overcoming the electrochemical stability window and operational temperature limits of aqueous electrolyte solutions in secondary zinc-base...

Nature Nanotechnology, Published online: 17 November 2025; doi:10.1038/s41565-025-02060-6Aqueous-hydrotrope hybrid liquid electrolyte solutions enable overcoming the electrochemical stability window and operational temperature limits of aqueous electrolyte solutions in secondary zinc-based batteries, also improving the battery performance.

Nature Nanotechnology, Published online: 17 November 2025; doi:10.1038/s41565-025-02056-2Electron avalanche multiplication can enable an all-optical modulator controlled by single photons.

Nature Nanotechnology, Published online: 17 November 2025; doi:10.1038/s41565-025-02059-zMultielectron molecular CO2 reduction in acid is challenged by weak CO binding and competing hydrogen evolution. Here a methanol Faradaic efficiency of 62% is achieved in acid by tuning the microenvironment with cationic, hydrophobic and aerophilic layers.

Aqueous-hydrotrope hybrid liquid electrolyte solutions enable overcoming the electrochemical stability window and operational temperature limits of aqueous electrolyte solutions in secondary zinc-base...

Electron avalanche multiplication can enable an all-optical modulator controlled by single photons.

Multielectron molecular CO2 reduction in acid is challenged by weak CO binding and competing hydrogen evolution. Here a methanol Faradaic efficiency of 62% is achieved in acid by tuning the microenvir...

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Nature Nanotechnology, Published online: 14 November 2025; doi:10.1038/s41565-025-02077-xSingle-molecule tracking reveals nanoscale domains within fused-in-sarcoma condensates. These nanodomains migrate to the condensate surface during ageing, seeding amyotrophic lateral sclerosis-linked fibrils, a process accelerated by small-molecule drugs.

Single-molecule tracking reveals nanoscale domains within fused-in-sarcoma condensates. These nanodomains migrate to the condensate surface during ageing, seeding amyotrophic lateral sclerosis-linked ...

Nature Nanotechnology, Published online: 13 November 2025; doi:10.1038/s41565-025-02095-9Metal–organic frameworks are transitioning from laboratory curiosity to industrially viable materials driven by extensive community efforts to enhance their functionality and stability, and by breakthroughs in large-scale manufacturing.

Nature Nanotechnology, Published online: 13 November 2025; doi:10.1038/s41565-025-02051-7An optimized gold nanolayer drives record efficiency in perovskite triple-junction solar cells, bringing laboratory performance closer to theoretical limits.

Nature Nanotechnology, Published online: 12 November 2025; doi:10.1038/s41565-025-02047-3A two-step boost with tumour-specific lipids and untranslated regions ensures safe, precise and effective mRNA expression.

Nature Nanotechnology, Published online: 12 November 2025; doi:10.1038/s41565-025-02035-7The lively debate on nanotechnology that started 20 years ago spurred a collaborative effort between the private and public sectors that developed as the field was growing, leading to the creation of a regulatory framework that underpins today’s successful implementation of nanotechnology. Emerging technologies such as artificial intelligence should take notice.

Nature Nanotechnology, Published online: 11 November 2025; doi:10.1038/s41565-025-02052-6By unifying data from engineered β-barrel nanopores and supported by modelling, it is demonstrated that the lumen charge in a β-barrel nanopore governs rectification and voltage-driven gating, with applications in computing using nanofluidic synapses.

By unifying data from engineered β-barrel nanopores and supported by modelling, it is demonstrated that the lumen charge in a β-barrel nanopore governs rectification and voltage-driven gating, with ap...

Franklin was no victim in how the DNA double helix was solved. An overlooked letter and an unpublished news article, both written in 1953, reveal that she was an equal player.

Nature Nanotechnology, Published online: 07 November 2025; doi:10.1038/s41565-025-02044-6This work presents a degradable ionizable lipid, AMG1541, for mRNA vaccines that significantly enhances potency and enables similar protective immunity at doses 100-fold lower than current standards, while also reducing toxicity and improving clearance in vivo.

Nature Nanotechnology, Published online: 05 November 2025; doi:10.1038/s41565-025-02043-7Hong–Ou–Mandel experiments on a quantum photonic chip demonstrate on-chip quantum interference of indistinguishable single photons with visibilities exceeding 0.97 for two molecules separately coupled to two waveguides.

Nature Nanotechnology, Published online: 05 November 2025; doi:10.1038/s41565-025-02041-9Using supramolecular chemistry principles, thermodynamically metastable, yet kinetically stable, poly(disulfide)s with tunable mechanical properties can be recycled into crystalline monomers with quantitative yields and monomer purity >90%.

Nature Nanotechnology, Published online: 03 November 2025; doi:10.1038/s41565-025-02029-5A gallium-based, iron-embedded liquid metal catalyst enables reversible, magnetic-field-controlled switching between atomically dispersed and clustered iron states, achieving tunable production of CH₃OOH and CH₃COOH under ambient conditions.

Nature Nanotechnology, Published online: 31 October 2025; doi:10.1038/s41565-025-02046-4A ROS-chemotactic antioxidative nanoscavenger prevents acute thrombosis by protecting vascular endothelial cells from oxidative stress, while circumventing the bleeding risk associated with current clinical antithrombotic drugs.

Nature Nanotechnology, Published online: 30 October 2025; doi:10.1038/s41565-025-02006-yA gallium arsenide-based terahertz quantum cascade laser harnesses graphene plasmons and optical nonlinearity to push the laser emission into the elusive far-end of the terahertz region.