Nadine Hillock
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nadinehillock.bsky.social
Nadine Hillock
@nadinehillock.bsky.social
Public Health Pharmacist Researcher, University of Adelaide (#antimicrobialresistance #AMR #AMS #HTA #healthpolicy #pharmacoepidemiology #medsafety #healtheconomics), Salsa dancer, Kiwi 🇳🇿, Aussie 🇦🇺, Mum, Wife, PhD. #OneHealth
Reposted by Nadine Hillock
🌍 Symposium 4 - Emerging Threats & Novel Solutions

Explore new frontiers in #infection control and #vaccines with Andrew Stewardson and Christopher Blyth.
Innovation shaping tomorrow’s #health.
👉 Register now: antimicrobials.com.au
#Antimicrobials2026 #AMR #IDsky #Medsky #clinmicrosky
November 6, 2025 at 11:31 AM
Hardly any National Action Plans to address antimicrobial resistance include reducing antibiotic use as an explicit goal 🤯

Report shows only 3 countries had a significant reduction in sales after implementing their NAPs: Jordan, Sth Africa & Indonesia 👏👏
#AMR #NAP
doi.org/10.1017/ice....
September 20, 2025 at 4:20 AM
‘Pharma companies make money on a new drug by selling a lot or charging a lot - but with antimicrobials neither is possible.’ - Andrew Bowskill #AAMRNet.
Delinking funding from use is the only way to stimulate investment in new antimicrobials #MTPConnect #AMR #antimicrobials @drewabow.bsky.social
July 14, 2025 at 3:30 AM
Surveillance of antimicrobial use and resistance ‘in isolation is like counting raindrops in a thunderstorm’ - we need more investment in innovation and prevention of AMR. Dr Richard Alm
Speaking in Adelaide #MTPConnect #AAMRNet #AMR #PublicHealth #antimicrobials @carb-x.bsky.social
July 14, 2025 at 3:09 AM
Study highlights higher risk of multidrug-resistant pathogens in cancer patients: analysis of US data compared cancer outpatient cohort with non-cancer patients.
eg. 2-3x higher incidence of carbopenem-resistant P.aeruginosa #AMR #AMS
www.thelancet.com/journals/lan...
‪@thelancetoncol.bsky.social‬
Incidence and prevalence of antimicrobial resistance in outpatients with cancer: a multicentre, retrospective, cohort study
AMR proportions and IRRs for most key pathogens were up to three-times higher in isolates from outpatients with cancer than those without cancer, highlighting the need for enhanced surveillance, infec...
www.thelancet.com
June 9, 2025 at 11:33 PM
Tebipenem - a new oral carbapenem for complicated UTIs - efficacy data is good 😀

Marketing now the challenge - how to make it profitable for pharma but prevent overuse? 🤔

De-linked funding model needed!

#tebipenem #PIVOT-PO #antibiotic #de-linked #AMR #AMS

www.globenewswire.com/news-release...
Spero Therapeutics and GSK Announce PIVOT-PO Phase 3 Study for Tebipenem HBr Stopped Early for Efficacy Following Review by Independent Data Monitoring Committee
If approved, tebipenem HBr could be the first oral carbapenem antibiotic for US patients with complicated urinary tract infections (cUTIs) An estimated 2.9...
www.globenewswire.com
May 30, 2025 at 12:10 AM
Reposted by Nadine Hillock
Topical use of last-line antibiotics during surgery largely undocumented - potential focus for stewardship and improved governance. Australian surveillance data illustrates rifampicin use not uncommon.
doi.org/10.1017/ash....
Off-label use of intravenous rifampicin during surgery: analysis of Australian surveillance data and retrospective audit at a tertiary hospital | Antimicrobial Stewardship & Healthcare Epidemiolog...
Off-label use of intravenous rifampicin during surgery: analysis of Australian surveillance data and retrospective audit at a tertiary hospital - Volume 5 Issue 1
doi.org
April 24, 2025 at 11:38 AM
Reposted by Nadine Hillock
To celebrate #IDPharmacistsDay look out for the videos from AdPha.au pharmacists showcasing their contributions to Innovations in Infectious Diseases @adphaau.bsky.social @nadinehillock.bsky.social @sonkoning.bsky.social @leggwamy.bsky.social @sidpharm.bsky.social
May 21, 2025 at 10:50 PM
Reposted by Nadine Hillock
Analysis of over 208K Salmonella genomes find that #AMR varies by region, source, and serovar, with increases linked to poultry and environment. Antibiotic use, agriculture, and climate drive AMR, offering insights into global spread and evolution.
#OneHealth

www.nature.com/articles/s41...
A global atlas and drivers of antimicrobial resistance in Salmonella during 1900-2023 - Nature Communications
Salmonella is a major cause of foodborne disease worldwide. Authors created a Salmonella database and present a genetic atlas of antimicrobial resistance, identifying some socioeconomic and environmen...
www.nature.com
May 18, 2025 at 5:04 AM
Reposted by Nadine Hillock
This large multi-center study shows cancer patients are infected with #AMR bacteria at 1.2 to 3 times higher rates due to frequent hospital visits and antibiotic use. This highlights the need for better antibiotic #stewardship and surveillance in these patients.

www.thelancet.com/journals/lan...
Incidence and prevalence of antimicrobial resistance in outpatients with cancer: a multicentre, retrospective, cohort study
AMR proportions and IRRs for most key pathogens were up to three-times higher in isolates from outpatients with cancer than those without cancer, highlighting the need for enhanced surveillance, infec...
www.thelancet.com
May 4, 2025 at 5:59 AM
Reposted by Nadine Hillock
🧪 Antibiotics in our rivers: a global problem

A new study has found that 8,500 tonnes of antibiotics from human use end up in rivers every year. In 6 million km of rivers, levels are high enough to harm ecosystems or promote resistance.

🔗 doi.org/10.1093/pnas...

#SciComm #WaterQuality #AMR
Antibiotics in the global river system arising from human consumption
Abstract. The presence of antibiotics in surface waters poses risks to aquatic ecosystems and human health due to their toxicity and influence on antimicro
doi.org
May 12, 2025 at 4:28 AM
Interesting webinar coming up on antimicrobial clinical trials conducted after marketing
#antimicrobial #AMR #ID
@steventong.bsky.social #PatrickHarris @gardp.bsky.social

register.gotowebinar.com/register/755...
register.gotowebinar.com
May 9, 2025 at 12:13 AM
Sprinkles and washes ... the true extent of topical rifampicin use during surgery is unclear due to lack of documentation - a huge opportunity for stewardship and better governance
bit.ly/42nFmQT
Thanks to my co-authors Matt Rawlins and @edraby.bsky.social

#AMS #off-label #rifampicin #AMR #NAUSP
Off-label use of intravenous rifampicin during surgery: analysis of Australian surveillance data and retrospective audit at a tertiary hospital | Antimicrobial Stewardship & Healthcare Epidemiolog...
Off-label use of intravenous rifampicin during surgery: analysis of Australian surveillance data and retrospective audit at a tertiary hospital - Volume 5 Issue 1
bit.ly
April 23, 2025 at 7:27 AM
Price of pretomanid to drop by 25% to increase accessibility for patients with TB. Great example of how global public-private partnerships can increase access to antimicrobials while maintaining economic viability for manufacturing #TB #publichealth #antimicrobials

www.stoptb.org/news/global-...
Global Drug Facility Announces Another Big Price Drop: 25% Reduction in the Price of Pretomanid | Stop TB Partnership
www.stoptb.org
April 22, 2025 at 11:49 PM
Reposted by Nadine Hillock
Large study ties early-life antibiotic exposure to higher risk of asthma, allergies, other conditions

The authors of the observational study say the findings highlight the need for more judicious antibiotic prescribing in children under age 2.

www.cidrap.umn.edu/a...
April 18, 2025 at 4:44 PM
Deaths due to antimicrobial resistance are increasing, especially in children in South East Asia and Africa.

New study estimates 3 million kids died in 2022 globally due to AMR @cidrap.bsky.social #AMR #publichealth #mortality #antibioticresistance

www.cidrap.umn.edu/antimicrobia...
More than 3 million child deaths in 2022 linked to antimicrobial resistance
www.cidrap.umn.edu
April 15, 2025 at 12:24 AM
Reposted by Nadine Hillock
Go where the money is? No go where the AMR is.
Asia remains the epicenter of antimicrobial resistance, yet is underrepresented in clinical trials.
David Paterson’s keynote at #ESCMIDGlobal 2025 @escmid.bsky.social
underscores the urgency the need for urgent action 🙌
#AMR #ESCMIDGlobal2025
April 12, 2025 at 10:59 AM
Reposted by Nadine Hillock
The most anticipated RCT in ID
🔥SNAP RCT🔥The largest RCT 2 date in SA bactermia
N:1341
Cefazolin Vs ASPs ((flu)cloxacillin) for MSSA bacteremia
Cefazolin is non-inferior (90d mortality)& less AKI than ASPs
A practice-changer RCT that must change the guidelines
#ESCMIDGlobal #IDSky
April 12, 2025 at 3:09 PM
Reposted by Nadine Hillock
@steventong.bsky.social presents the results of the PSSA domain of the SNAP 🫰 trial - the worlds largest trial of staph aureus bacteremia - at #ESCMID2025

fluclox resulted in higher mortality and more AKI compared to penicillin for PSSA
April 12, 2025 at 2:45 PM
JAMA review of Staph aureus bacteraemia.
Empiric treatment should include MRSA cover in areas with rates >5% or in patients with risk MRSA risk factors
#SAB @jama.com @steventong.bsky.social
April 13, 2025 at 2:43 AM
Timely access to appropriate antimicrobials is essential for patient care, antimicrobial stewardship & minimising the risk of resistance - excellent summary of the issues here: amr.solutions/2025/04/07/y...

Thanks to @johnhrexmd.bsky.social for highlighting our paper

#AMR #AntibioticAccess #AMS 💊
You reach for the antibiotic ... and it's not there!
Dear All (with thanks to Louise for co-authoring and with a wonkish alert … settle in for the ride!), Today’s newsletter discusses the intersection of three themes around antibiotic access. Recall fir...
amr.solutions
April 7, 2025 at 11:47 PM
Reposted by Nadine Hillock
🔔 NEW in the Medical Journal of Australia

Shortages of benzathine benzylpenicillin G in Australia highlight the need for new sovereign manufacturing capability

✍️ Rosemary Wyber, Glenn Pearson and Laurens Manning

OPEN ACCESS www.mja.com.au/journal/2025...
March 20, 2025 at 10:00 PM