Morandi Research Group
@morandilab.bsky.social
Morandi Research Group @ETH Zurich - https://morandi.ethz.ch/
Now in its final version @jacs.acspublications.org ! pubs.acs.org/doi/10.1021/...
Congrats to @fruepp.bsky.social, Vasily Grebennikov, Mykola Avramenko, Marc-Olivier Ebert "Kinetic, Spectroscopic, and Computational Investigation of Oxidative Aminative Alkene Cleavage Reveals an N-Iodonium-Iminoiodinane Pathway" now @chemrxiv.org - chemrxiv.org/engage/chemr...
November 3, 2025 at 5:39 PM
Now in its final version @jacs.acspublications.org ! pubs.acs.org/doi/10.1021/...
Reposted by Morandi Research Group
It’s finally happening!🎉 The Reisenbauer Lab will open in February at ISTA (www.reisenbauerlab.com
).
We’re starting to build our team and are looking for enthusiastic scientists to join us.
I feel deeply grateful to my mentors, colleagues, and family for all their support. Excited for what’s next!
).
We’re starting to build our team and are looking for enthusiastic scientists to join us.
I feel deeply grateful to my mentors, colleagues, and family for all their support. Excited for what’s next!
Home | Reisenbauer Lab
The Reisenbauer Lab is a research group in biocatalysis and enzyme engineering at the IST Austria.
www.reisenbauerlab.com
October 24, 2025 at 11:43 AM
It’s finally happening!🎉 The Reisenbauer Lab will open in February at ISTA (www.reisenbauerlab.com
).
We’re starting to build our team and are looking for enthusiastic scientists to join us.
I feel deeply grateful to my mentors, colleagues, and family for all their support. Excited for what’s next!
).
We’re starting to build our team and are looking for enthusiastic scientists to join us.
I feel deeply grateful to my mentors, colleagues, and family for all their support. Excited for what’s next!
Congrats to Emilien, Maurus and Giorgia! Metal- and CO-Free Carbonylation of Alkyl Iodides @jacs.acspublications.org pubs.acs.org/doi/abs/10.1...
October 17, 2025 at 5:09 PM
Congrats to Emilien, Maurus and Giorgia! Metal- and CO-Free Carbonylation of Alkyl Iodides @jacs.acspublications.org pubs.acs.org/doi/abs/10.1...
Reposted by Morandi Research Group
Great to see this published!
In short, we introduced causal inference logic to test which of metal electronics, ancillary ligand sterics and metal coordination number (CN) directly affect the rate of reductive elimination at Pd(II) (and presumably other metals...)
1/
In short, we introduced causal inference logic to test which of metal electronics, ancillary ligand sterics and metal coordination number (CN) directly affect the rate of reductive elimination at Pd(II) (and presumably other metals...)
1/
Congrats to @mixalhsmpogdos.bsky.social, @sevenroediger.bsky.social, @fruepp.bsky.social, Nathalie, Patrick, Fabio and Jan on this epic study of C-N red. elim. in @jacs.acspublications.org - using causal inference, organometallics, electrochemistry, kinetics and DFT. pubs.acs.org/doi/full/10....
October 14, 2025 at 6:15 PM
Great to see this published!
In short, we introduced causal inference logic to test which of metal electronics, ancillary ligand sterics and metal coordination number (CN) directly affect the rate of reductive elimination at Pd(II) (and presumably other metals...)
1/
In short, we introduced causal inference logic to test which of metal electronics, ancillary ligand sterics and metal coordination number (CN) directly affect the rate of reductive elimination at Pd(II) (and presumably other metals...)
1/
Congrats Bence on this @orgsynth.bsky.social prep describing a scalable nitrogen insertion protocol. Thanks to the Dixon lab for checking. 10.15227/orgsyn.102.0465
October 14, 2025 at 11:27 AM
Congrats Bence on this @orgsynth.bsky.social prep describing a scalable nitrogen insertion protocol. Thanks to the Dixon lab for checking. 10.15227/orgsyn.102.0465
Congrats to Sooyeon Moon, Julia Reisenbauer, Ann-Sophie Paschke, Alessandro Scotto, Luca Terraneo, Niklas Brenner, as well as collaborators from Spirochem AG Quentin Lefebvre, Thomas Fessard for a continuous flow nitrogen atom insertion. @chemcomm.rsc.org @Innosuisse. pubs.rsc.org/en/content/a...
October 14, 2025 at 10:01 AM
Congrats to Sooyeon Moon, Julia Reisenbauer, Ann-Sophie Paschke, Alessandro Scotto, Luca Terraneo, Niklas Brenner, as well as collaborators from Spirochem AG Quentin Lefebvre, Thomas Fessard for a continuous flow nitrogen atom insertion. @chemcomm.rsc.org @Innosuisse. pubs.rsc.org/en/content/a...
Congrats to @mixalhsmpogdos.bsky.social, @sevenroediger.bsky.social, @fruepp.bsky.social, Nathalie, Patrick, Fabio and Jan on this epic study of C-N red. elim. in @jacs.acspublications.org - using causal inference, organometallics, electrochemistry, kinetics and DFT. pubs.acs.org/doi/full/10....
October 14, 2025 at 9:50 AM
Congrats to @mixalhsmpogdos.bsky.social, @sevenroediger.bsky.social, @fruepp.bsky.social, Nathalie, Patrick, Fabio and Jan on this epic study of C-N red. elim. in @jacs.acspublications.org - using causal inference, organometallics, electrochemistry, kinetics and DFT. pubs.acs.org/doi/full/10....
Congrats to Alberto and Patrick! @ethz.ch. youtu.be/NcMTOI25yb8?...
Recycling of organic pollutants: Nominated for the Spark Award
YouTube video by ETH News for Industry
youtu.be
October 14, 2025 at 9:34 AM
Congrats to Alberto and Patrick! @ethz.ch. youtu.be/NcMTOI25yb8?...
Congrats to @fruepp.bsky.social, Vasily Grebennikov, Mykola Avramenko, Marc-Olivier Ebert "Kinetic, Spectroscopic, and Computational Investigation of Oxidative Aminative Alkene Cleavage Reveals an N-Iodonium-Iminoiodinane Pathway" now @chemrxiv.org - chemrxiv.org/engage/chemr...
September 2, 2025 at 7:18 PM
Congrats to @fruepp.bsky.social, Vasily Grebennikov, Mykola Avramenko, Marc-Olivier Ebert "Kinetic, Spectroscopic, and Computational Investigation of Oxidative Aminative Alkene Cleavage Reveals an N-Iodonium-Iminoiodinane Pathway" now @chemrxiv.org - chemrxiv.org/engage/chemr...
Congrats to Ann-Sophie Paschke, @ybraegger.bsky.social, Bence Botlik, Erich Staudinger, @origreen.bsky.social! "Carbon-to-nitrogen atom swap enables direct access to benzimidazoles from drug-like indoles". www.nature.com/articles/s41.... @natchem.nature.com.
September 2, 2025 at 6:49 PM
Congrats to Ann-Sophie Paschke, @ybraegger.bsky.social, Bence Botlik, Erich Staudinger, @origreen.bsky.social! "Carbon-to-nitrogen atom swap enables direct access to benzimidazoles from drug-like indoles". www.nature.com/articles/s41.... @natchem.nature.com.
Reposted by Morandi Research Group
Their electrochemical Lindane destruction has so much potential. Just thinking about the Lindane scandal in Basel-Kleinhüningen, where it was mixed into the street concrete…
August 21, 2025 at 7:56 PM
Their electrochemical Lindane destruction has so much potential. Just thinking about the Lindane scandal in Basel-Kleinhüningen, where it was mixed into the street concrete…
Reposted by Morandi Research Group
Join us today to hear from Ann-Sophie Paschke and Stefanie Schiele from the @morandilab.bsky.social about their work on C-to-N atom swapping reactions!! Thanks to Karim for hosting and editing!
Link: youtu.be/D513hX1gOTg
@chemicalscience.rsc.org
doi.org/10.1039/D5SC...
Link: youtu.be/D513hX1gOTg
@chemicalscience.rsc.org
doi.org/10.1039/D5SC...
August 9, 2025 at 1:38 PM
Join us today to hear from Ann-Sophie Paschke and Stefanie Schiele from the @morandilab.bsky.social about their work on C-to-N atom swapping reactions!! Thanks to Karim for hosting and editing!
Link: youtu.be/D513hX1gOTg
@chemicalscience.rsc.org
doi.org/10.1039/D5SC...
Link: youtu.be/D513hX1gOTg
@chemicalscience.rsc.org
doi.org/10.1039/D5SC...
Congrats to Elliott, @hls111.bsky.social, Olivera, Patrick, Alexander and Daniel! Ligand Design Enables the Palladium-Catalyzed Intermolecular Carbochlorocarbonylation of Alkynes and Cyclopentenone Formation @jacs.acspublications.org pubs.acs.org/doi/full/10....
August 6, 2025 at 8:51 PM
Congrats to Elliott, @hls111.bsky.social, Olivera, Patrick, Alexander and Daniel! Ligand Design Enables the Palladium-Catalyzed Intermolecular Carbochlorocarbonylation of Alkynes and Cyclopentenone Formation @jacs.acspublications.org pubs.acs.org/doi/full/10....
Reposted by Morandi Research Group
Last day at #eucomc2025 starts with #plenary lecture @morandilab.bsky.social 🇨🇭 @ethz.ch introducing new concepts for atom and funcional transfer #Ni #organicsynthesis
July 10, 2025 at 7:28 AM
Last day at #eucomc2025 starts with #plenary lecture @morandilab.bsky.social 🇨🇭 @ethz.ch introducing new concepts for atom and funcional transfer #Ni #organicsynthesis
Congrats to Ann-Sophie Paschke, Eva Meeus, Florin and our collaborators from the pharmacy institute M. Masota and @nathalie-grob.bsky.social - Late-Stage Diversification of Peptides and Peptide Drugs through Nitrogen Atom Insertion | @ChemRxiv - go.shr.lc/44mL6Kg
July 4, 2025 at 11:10 AM
Congrats to Ann-Sophie Paschke, Eva Meeus, Florin and our collaborators from the pharmacy institute M. Masota and @nathalie-grob.bsky.social - Late-Stage Diversification of Peptides and Peptide Drugs through Nitrogen Atom Insertion | @ChemRxiv - go.shr.lc/44mL6Kg
Congrats to Tanner Jankins, Barnabé Berger, Françoise A. Aouane, Sergio Barbeira-Arán, Christophe Didier, Bettina Hürlimann and Claudius Zimmer: C–H Functionalization via Single Atom Metathesis of C–H and C–X Bonds @jacs.acspublications.org pubs.acs.org/doi/10.1021/...
June 18, 2025 at 2:05 PM
Congrats to Tanner Jankins, Barnabé Berger, Françoise A. Aouane, Sergio Barbeira-Arán, Christophe Didier, Bettina Hürlimann and Claudius Zimmer: C–H Functionalization via Single Atom Metathesis of C–H and C–X Bonds @jacs.acspublications.org pubs.acs.org/doi/10.1021/...
Congrats to Sooyeon Moon, Julia Reisenbauer, Ann-Sophie Paschke, Alessandro Scotto, Luca Terraneo, Niklas Brenner, as well as collaborators from Spirochem AG Quentin Lefebvre, Thomas Fessard for a continuous flow approach to nitrogen atom insertion. @Innosuisse. chemrxiv.org/engage/chemr...
Efficient Optimization and Synthesis of Diverse Azaarenes via Nitrogen Atom Insertion under Continuous Flow Conditions
We report the development of a continuous flow approach to nitrogen atom insertion. The setup is modular, enabling the rapid optimization of reaction conditions for a wide range of substrates. The mil...
chemrxiv.org
June 18, 2025 at 1:58 PM
Congrats to Sooyeon Moon, Julia Reisenbauer, Ann-Sophie Paschke, Alessandro Scotto, Luca Terraneo, Niklas Brenner, as well as collaborators from Spirochem AG Quentin Lefebvre, Thomas Fessard for a continuous flow approach to nitrogen atom insertion. @Innosuisse. chemrxiv.org/engage/chemr...
Congrats to Ann-Sophie Paschke, Stefanie Schiele, Camille Pinard, and Filippo Sandrini: Chemodivergent C-to-N atom swap pubs.rsc.org/en/content/a.... Please also check our other paper (10.26434/chemrxiv-2024-prwm8) as well Studer's work.
Chemodivergent C-to-N atom swap from benzofurans to benzisoxazoles and benzoxazoles
Facile derivatization of biologically active compounds without prefunctionalization expands the chemical space and accelerates the discovery of new molecules. Atom swap reactions have recently emerged...
pubs.rsc.org
June 18, 2025 at 1:44 PM
Congrats to Ann-Sophie Paschke, Stefanie Schiele, Camille Pinard, and Filippo Sandrini: Chemodivergent C-to-N atom swap pubs.rsc.org/en/content/a.... Please also check our other paper (10.26434/chemrxiv-2024-prwm8) as well Studer's work.
Reposted by Morandi Research Group
My lab at @ethzurich.bsky.social is looking for a motivated PhD student. We develop chemical tools for advanced fluorescence microscopy 🔬 and work at the interface of synthetic chemistry ⚗️ and protein engineering 🦠. Sharing with skilled Master students appreciated. More info at tinyurl.com/2dbjk5ty
April 8, 2025 at 8:06 AM
My lab at @ethzurich.bsky.social is looking for a motivated PhD student. We develop chemical tools for advanced fluorescence microscopy 🔬 and work at the interface of synthetic chemistry ⚗️ and protein engineering 🦠. Sharing with skilled Master students appreciated. More info at tinyurl.com/2dbjk5ty
Congrats to @mixalhsmpogdos.bsky.social, @sevenroediger.bsky.social, @fruepp.bsky.social, Patrick, Nathalie, Fabio on this epic study of the factors governing reductive elimination - using causal inference, organometallics, electrochemistry, kinetics and DFT
@chemrxiv.bsky.social go.shr.lc/4j8O5MM
@chemrxiv.bsky.social go.shr.lc/4j8O5MM
Metal Electronics Mediate Steric and Coordination Number Effects on Palladium (II) C–X Reductive Elimination
Reductive elimination is the key bond-forming elementary step in many transition metal catalyzed reactions relevant to the synthesis of pharmaceuticals, materials and fine chemicals. Metal electronics...
go.shr.lc
April 11, 2025 at 8:24 PM
Congrats to @mixalhsmpogdos.bsky.social, @sevenroediger.bsky.social, @fruepp.bsky.social, Patrick, Nathalie, Fabio on this epic study of the factors governing reductive elimination - using causal inference, organometallics, electrochemistry, kinetics and DFT
@chemrxiv.bsky.social go.shr.lc/4j8O5MM
@chemrxiv.bsky.social go.shr.lc/4j8O5MM
Many congrats to Emilien Le Saux for this new publication in @jacs.acspublications.org describing a catalytic approach to Transfer Iodination from Aryl Iodides to Nonactivated C(sp3)–H Bonds.
pubs.acs.org/doi/10.1021/...
pubs.acs.org/doi/10.1021/...
Palladium-Catalyzed Transfer Iodination from Aryl Iodides to Nonactivated C(sp3)–H Bonds
We report a new strategy for the catalytic iodination of nonactivated C(sp3)–H bonds. The method merges the concepts of shuttle and light-enabled palladium catalysis to employ aryl iodides as both hyd...
pubs.acs.org
April 8, 2025 at 1:03 PM
Many congrats to Emilien Le Saux for this new publication in @jacs.acspublications.org describing a catalytic approach to Transfer Iodination from Aryl Iodides to Nonactivated C(sp3)–H Bonds.
pubs.acs.org/doi/10.1021/...
pubs.acs.org/doi/10.1021/...
Reposted by Morandi Research Group
Our @snf-fns-ch.bsky.social research project "Hypervalent iodine reagents for peptide and protein modification and applications in chemical biology" has been accepted! 2 PhD and one postdoc positions are now open @lcsolab.bsky.social For more details to apply, See:
www.epfl.ch/labs/lcso/gr...
www.epfl.ch/labs/lcso/gr...
March 31, 2025 at 11:55 AM
Our @snf-fns-ch.bsky.social research project "Hypervalent iodine reagents for peptide and protein modification and applications in chemical biology" has been accepted! 2 PhD and one postdoc positions are now open @lcsolab.bsky.social For more details to apply, See:
www.epfl.ch/labs/lcso/gr...
www.epfl.ch/labs/lcso/gr...
Many Congrats to @ybraegger.bsky.social,
Ann-Sophie Paschke, Nima Nasiri, Bence Botlik
and Francesco Felician for this masterpiece! Oxidative amination by nitrogen atom insertion into carbon-carbon double bonds in Science, @ethzurich.bsky.social.
www.science.org/doi/10.1126/...
Ann-Sophie Paschke, Nima Nasiri, Bence Botlik
and Francesco Felician for this masterpiece! Oxidative amination by nitrogen atom insertion into carbon-carbon double bonds in Science, @ethzurich.bsky.social.
www.science.org/doi/10.1126/...
Oxidative amination by nitrogen atom insertion into carbon-carbon double bonds
The synthesis of nitrogen-containing molecules through carbon–nitrogen (C–N) bond formation is critical for the discovery and preparation of medicines, agrochemicals, and materials. Here, we report th...
www.science.org
March 7, 2025 at 8:50 AM
Many Congrats to @ybraegger.bsky.social,
Ann-Sophie Paschke, Nima Nasiri, Bence Botlik
and Francesco Felician for this masterpiece! Oxidative amination by nitrogen atom insertion into carbon-carbon double bonds in Science, @ethzurich.bsky.social.
www.science.org/doi/10.1126/...
Ann-Sophie Paschke, Nima Nasiri, Bence Botlik
and Francesco Felician for this masterpiece! Oxidative amination by nitrogen atom insertion into carbon-carbon double bonds in Science, @ethzurich.bsky.social.
www.science.org/doi/10.1126/...
Reposted by Morandi Research Group
Are you inspired by complex reaction mechanisms and organometallic chemistry? At the European Symposium on Organic Chemistry (@ESOC_ISC) in Copenhagen (www.esoc2025.com) Jennifer A. Love (
@jenlove.bsky.social
) and Bill Morandi (
@morandilab.bsky.social
) will share their latest results!
@jenlove.bsky.social
) and Bill Morandi (
@morandilab.bsky.social
) will share their latest results!
March 3, 2025 at 8:45 AM
Are you inspired by complex reaction mechanisms and organometallic chemistry? At the European Symposium on Organic Chemistry (@ESOC_ISC) in Copenhagen (www.esoc2025.com) Jennifer A. Love (
@jenlove.bsky.social
) and Bill Morandi (
@morandilab.bsky.social
) will share their latest results!
@jenlove.bsky.social
) and Bill Morandi (
@morandilab.bsky.social
) will share their latest results!
Congrats to @sevenroediger.bsky.social and team as well as Tanner Jankins and team for having their papers highlighted this month in OPRD items of interest to process chem 😀 pubs.acs.org/doi/10.1021/...
Some Items of Interest to Process R&D Chemists and Engineers
pubs.acs.org
February 20, 2025 at 8:26 PM
Congrats to @sevenroediger.bsky.social and team as well as Tanner Jankins and team for having their papers highlighted this month in OPRD items of interest to process chem 😀 pubs.acs.org/doi/10.1021/...