Nils Frank
@nilsfrank99.bsky.social
PhD student in the List-Lab (Max-Planck für Kohlenforschung) | Previously: MedChem Intern @Roche | MRes @University of Oxford (Ed Anderson-, Duarte-Group) | KIT Karlsruhe (BSc)
Reposted by Nils Frank
The combined power of halogen bonding and asymmetric counteranion-directed catalysis = XB-ACDC: pubs.acs.org/doi/10.1021/.... Thanks to @mertenlab.bsky.social for structure elucidation and to the List group for this beautiful cooperation! A perfect #RESOLV project! @solvationsci.bsky.social
Asymmetric Counteranion-Directed Halogen Bonding Catalysis
Halogen bonding has been established as a promising tool in organocatalysis. Asymmetric processes are nevertheless scarce, and their applications are limited to a few studies applying chiral halogen b...
pubs.acs.org
March 3, 2025 at 7:40 PM
The combined power of halogen bonding and asymmetric counteranion-directed catalysis = XB-ACDC: pubs.acs.org/doi/10.1021/.... Thanks to @mertenlab.bsky.social for structure elucidation and to the List group for this beautiful cooperation! A perfect #RESOLV project! @solvationsci.bsky.social
Reposted by Nils Frank
The global oil industry appears to be backing away from renewable energy and returning to its core business of extracting and refining fossil fuels. Many companies are looking to increase oil and gas production.
Chevron and BP cutting thousands of jobs
Oil industry is broadly looking to cut costs, increase oil and gas production and cut renewable investments
www.chemistryworld.com
March 2, 2025 at 4:01 PM
The global oil industry appears to be backing away from renewable energy and returning to its core business of extracting and refining fossil fuels. Many companies are looking to increase oil and gas production.
Excited to share our first steps into the world of furan chemistry — an underexplored but increasingly important heterocycle in the shift away from fossil-based chemicals.
We hope to offer a robust method achieving "Birch"-type and fully reduced furans. pubs.acs.org/doi/10.1021/...
We hope to offer a robust method achieving "Birch"-type and fully reduced furans. pubs.acs.org/doi/10.1021/...
Bro̷nsted Acid-Catalyzed Reduction of Furans
Bioderived furans play a pivotal role in advancing defossilized chemical pathways. The complete reduction of furans currently relies on impractical metal-catalyzed hydrogenations at high pressures and temperatures. In addition, the Birch reduction of unbiased furans to 2,5-dihydrofurans remains an unsolved synthetic challenge. Herein, we report a mild Bro̷nsted acid-catalyzed reduction of furans to 2,5-dihydro- and/or tetrahydrofuran derivatives using silanes as reducing agents. In particular, the first formal Birch reduction of furan itself is achieved. Mechanistic investigations reveal an intricate behavior of HFIP as the crucial solvent, preventing the intrinsic polymerization behavior of furans under acidic conditions and introducing additional driving force by specific product binding.
pubs.acs.org
February 19, 2025 at 6:09 PM
Excited to share our first steps into the world of furan chemistry — an underexplored but increasingly important heterocycle in the shift away from fossil-based chemicals.
We hope to offer a robust method achieving "Birch"-type and fully reduced furans. pubs.acs.org/doi/10.1021/...
We hope to offer a robust method achieving "Birch"-type and fully reduced furans. pubs.acs.org/doi/10.1021/...
Reposted by Nils Frank
