Mendelspod
mendelspod.bsky.social
Mendelspod
@mendelspod.bsky.social
A podcast covering your stories in biology since 2011
Reposted by Mendelspod
Wonderful thread about polio virus, the vaccines, and why we need to keep vaccinating.
My replies are perpetually full of anti-vaxxers these days telling me about polio vaccines.

Not shockingly, most of what they are saying is wrong. Luckily, I trained with Vincent Racaniello & he taught me a few things about poliovirus.

So let’s discuss the king of the Picornaviridae👇🏻
December 19, 2024 at 12:38 PM
Reposted by Mendelspod
This is fascinating! Congrats @brunetlab.bsky.social & colleagues! Cool findings on vascular/pericyte & meningeal/perivascular fibroblast cell types - important to exercise to keep those 🧠 blood vessels young and functional 🏃‍♀️🏋️‍♂️...but also what are the fibroblasts up to?!? 👀 🧪 #BBB #fibroblast
December 19, 2024 at 1:11 PM
Reposted by Mendelspod
Autopsies of 15 COVID-19 cases showed SARS-CoV-2 in multiple organs (lungs, heart, liver, etc.) even in non-immunocompromised individuals.

The virus mutated differently in each organ, supporting theories of viral reservoirs and rapid evolution.

onlinelibrary.wiley.com/doi/abs/10.1...
Multi‐Organ Spread and Intra‐Host Diversity of SARS‐CoV‐2 Support Viral Persistence, Adaptation, and a Mechanism That Increases Evolvability
Intra-host diversity is an intricate phenomenon related to immune evasion, antiviral resistance, and evolutionary leaps along transmission chains. SARS-CoV-2 intra-host variation has been well-eviden....
onlinelibrary.wiley.com
December 14, 2024 at 10:47 PM
Reposted by Mendelspod
Over 30 prominent scientists call for a ban on the creation of a "mirror cell"--a microbe made of molecules that are mirror images of their natural forms. It could cause a mind-boggling global disaster. Here's my story [gift link] 🧪https://nyti.ms/3OUCXp6
A ‘Second Tree of Life’ Could Wreak Havoc, Scientists Warn (Gift Article)
Research on so-called mirror cells, which defy fundamental properties of living organisms, should be prohibited as too dangerous, biologists said.
nyti.ms
December 12, 2024 at 8:04 PM
Genome Informatics in the Age of AI With Ben Busby
@dcgenomics.bsky.social at DNAnexus
Genome Informatics in the Age of AI With Ben Busby, DNAnexus
Today we begin a new series co-produced with GenomeWeb on the state of genome informatics. To do that, we’re joined by Ben Busby, principal scientist at DNAnexus.
www.mendelspod.com
December 12, 2024 at 6:00 PM
Reposted by Mendelspod
As an early riser I have been observing this for decades, but only recently learned that it’s the earths shadow. Mind blown.
Earth’s shadow over the Pacific Ocean.
December 7, 2024 at 4:04 PM
Reposted by Mendelspod
Bay Area Winery meetup was delightful! And this is not the last one of the year! More meetups coming up before the holidays 🧬✨
December 7, 2024 at 8:54 PM
Reposted by Mendelspod
WOW! @UCLAHealth hiring Associate Dean for Health AI Innovation & Strategy and Director, @UCLA Center for AI & Smart Health! Tenure-track and non- options available. Opportunity to shape and drive #AI vision and strategy. Apply soon! recruit.apo.ucla.edu/JPF10032
Associate Dean for Health AI Innovation & Strategy and Director, UCLA Center for AI & Smart Health (non-tenured track)
University of California, Los Angeles is hiring. Apply now!
recruit.apo.ucla.edu
December 4, 2024 at 2:25 AM
Reposted by Mendelspod
This is f-tastic
Our Big Fantastic Virus Database (BFVD) is now published NAR! It contains protein structure predictions of major viral clades, enhanced by petabase-scale homology search and it's explorable on the web.
🌐 bfvd.foldseek.com
💾 bfvd.steineggerlab.workers.dev
📄 academic.oup.com/nar/advance-...
December 4, 2024 at 2:43 AM
Reposted by Mendelspod
Re-reposting @scottehensley.bsky.social post, since this is the same mutation identified in the recent paper in Science from my colleagues at @scripps.edu.

As always, nature gets there first. The more chances we give the virus, the more chances it'll hit goal...

www.science.org/doi/10.1126/...
December 6, 2024 at 2:01 AM