Nature Reviews Chemistry, Published online: 04 April 2025; doi:10.1038/s41570-025-00705-7Hypoxic tumours present considerable challenges in cancer treatment owing to their specific chemistry, biology and physics, which leads to resistances to conventional therapies. This Review explores innovative strategies based on supramolecular chemistry to overcome these obstacles and discusses future research directions that might help translating supramolecular approaches to the clinics.

Surfaces are well known to be complex entities that are extremely difficult to study, and any phenomenon that is related to them is consequently challenging to approach. Moving from the bulk to the nanoscale adds a further layer of complexity to the problem. Because SERS relies on surfaces at the nanoscale, a rigor

Nature Reviews Bioengineering, Published online: 25 March 2025; doi:10.1038/s44222-025-00302-9Achieving effective collaboration in bioengineering is an art and a science. Here we outline strategies for building and sustaining interdisciplinary partnerships, and outline challenges, opportunities and funding options for establishing and strengthening collaborative research.