Matt Hoare
@matthoare20.bsky.social
Assistant Professor of Hepatology at the University of Cambridge.
Honorary Consultant in Hepatology at Cambridge University Hospitals.
Honorary Consultant in Hepatology at Cambridge University Hospitals.
Reposted by Matt Hoare
🩺 Liver cancer cases could double by 2050
A new @thelancet.com Commission warns of 1.5M annual liver cancer cases by 2050 but says 60% are preventable through better HBV vaccination & alcohol reduction.
Prevention is possible. Action is urgent.
🔗 www.thelancet.com/journals/lan...
#SciComm 🧪
A new @thelancet.com Commission warns of 1.5M annual liver cancer cases by 2050 but says 60% are preventable through better HBV vaccination & alcohol reduction.
Prevention is possible. Action is urgent.
🔗 www.thelancet.com/journals/lan...
#SciComm 🧪
Reversing the rise of liver cancer
Imagine a future where the global incident cases of liver cancer almost doubles, rising
from 870 000 cases in 2022 to over 1·5 million in 2050. This scenario, and all the
attendant harms to health and...
www.thelancet.com
August 1, 2025 at 4:51 AM
🩺 Liver cancer cases could double by 2050
A new @thelancet.com Commission warns of 1.5M annual liver cancer cases by 2050 but says 60% are preventable through better HBV vaccination & alcohol reduction.
Prevention is possible. Action is urgent.
🔗 www.thelancet.com/journals/lan...
#SciComm 🧪
A new @thelancet.com Commission warns of 1.5M annual liver cancer cases by 2050 but says 60% are preventable through better HBV vaccination & alcohol reduction.
Prevention is possible. Action is urgent.
🔗 www.thelancet.com/journals/lan...
#SciComm 🧪
www.theguardian.com/society/2025...
Policy changes and enhanced early detection key to reducing death from HCC.
Policy changes and enhanced early detection key to reducing death from HCC.
Lifestyle changes and vaccination ‘could prevent most liver cancer cases’
Lancet Commission says three in five cases preventable with action on obesity, alcohol and hepatitis
www.theguardian.com
July 29, 2025 at 4:54 PM
www.theguardian.com/society/2025...
Policy changes and enhanced early detection key to reducing death from HCC.
Policy changes and enhanced early detection key to reducing death from HCC.
Reposted by Matt Hoare
Registrations for the Early Cancer Institute Annual Symposium 2025, focusing on the latest developments in early cancer research, are open!
📅 Thurs 9 October 2-6pm
📍 CRUK Cambridge Institute, CB2 0RE
Find out more and register ➡️ zurl.co/bH4wU
@cambridgebrc.bsky.social @cambridge-scm.bsky.social
📅 Thurs 9 October 2-6pm
📍 CRUK Cambridge Institute, CB2 0RE
Find out more and register ➡️ zurl.co/bH4wU
@cambridgebrc.bsky.social @cambridge-scm.bsky.social
July 25, 2025 at 9:00 AM
Registrations for the Early Cancer Institute Annual Symposium 2025, focusing on the latest developments in early cancer research, are open!
📅 Thurs 9 October 2-6pm
📍 CRUK Cambridge Institute, CB2 0RE
Find out more and register ➡️ zurl.co/bH4wU
@cambridgebrc.bsky.social @cambridge-scm.bsky.social
📅 Thurs 9 October 2-6pm
📍 CRUK Cambridge Institute, CB2 0RE
Find out more and register ➡️ zurl.co/bH4wU
@cambridgebrc.bsky.social @cambridge-scm.bsky.social
Great to be at the Bridgewater Hall in Manchester for the annual HCC-UK conference. Exciting day of great speakers.
March 27, 2025 at 2:39 PM
Great to be at the Bridgewater Hall in Manchester for the annual HCC-UK conference. Exciting day of great speakers.
Reposted by Matt Hoare
Excited to share our new preprint demonstrating somatic rescue mutations in a genetic liver disease! [1/12]
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Selection for somatic escape variants in SERPINA1 in the liver of patients with alpha-1 antitrypsin deficiency - Nature Genetics
The expansion of clones with distinct SERPINA1 somatic mutants in the livers of alpha-1 antitrypsin deficiency (A1AT) patients is consistent with convergent evolution. These variants interfere with th...
www.nature.com
March 12, 2025 at 5:29 PM
Excited to share our new preprint demonstrating somatic rescue mutations in a genetic liver disease! [1/12]
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Delighted to announce our new paper by Natalia Brzozowska published today, demonstrating somatic escape mutants from a deleterious germline disease.
rdcu.be/ecSNo
rdcu.be/ecSNo
Selection for somatic escape variants in SERPINA1 in the liver of patients with alpha-1 antitrypsin deficiency
Nature Genetics - The expansion of clones with distinct SERPINA1 somatic mutants in the livers of alpha-1 antitrypsin deficiency (A1AT) patients is consistent with convergent evolution. These...
rdcu.be
March 10, 2025 at 12:56 PM
Delighted to announce our new paper by Natalia Brzozowska published today, demonstrating somatic escape mutants from a deleterious germline disease.
rdcu.be/ecSNo
rdcu.be/ecSNo
Reposted by Matt Hoare
Delighted to have this work published today.
A superb collaboration with @matthoare20.bsky.social and @joechambers.bsky.social
www.nature.com/articles/s41...
A superb collaboration with @matthoare20.bsky.social and @joechambers.bsky.social
www.nature.com/articles/s41...
Selection for somatic escape variants in SERPINA1 in the liver of patients with alpha-1 antitrypsin deficiency - Nature Genetics
The expansion of clones with distinct SERPINA1 somatic mutants in the livers of alpha-1 antitrypsin deficiency (A1AT) patients is consistent with convergent evolution. These variants interfere with th...
www.nature.com
March 10, 2025 at 12:09 PM
Delighted to have this work published today.
A superb collaboration with @matthoare20.bsky.social and @joechambers.bsky.social
www.nature.com/articles/s41...
A superb collaboration with @matthoare20.bsky.social and @joechambers.bsky.social
www.nature.com/articles/s41...
Reposted by Matt Hoare
1/n
👩💻Research Assistant in Computational Biology
🧬analyse somatic mutations in #HCC
👨⚕️international collaboration with Dr Matt Hoare @matthoare20.bsky.social
🌍based at the Early Cancer Institute, University of Cambridge (UK)
🗓️apply by 31 March 2025 www.jobs.cam.ac.uk/job/50461/
👩💻Research Assistant in Computational Biology
🧬analyse somatic mutations in #HCC
👨⚕️international collaboration with Dr Matt Hoare @matthoare20.bsky.social
🌍based at the Early Cancer Institute, University of Cambridge (UK)
🗓️apply by 31 March 2025 www.jobs.cam.ac.uk/job/50461/
Research Assistant (Computational biology) (Fixed Term) - Job Opportunities - University of Cambridge
Research Assistant (Computational biology) (Fixed Term) in the Department of Oncology at the University of Cambridge.
www.jobs.cam.ac.uk
February 27, 2025 at 5:56 PM
1/n
👩💻Research Assistant in Computational Biology
🧬analyse somatic mutations in #HCC
👨⚕️international collaboration with Dr Matt Hoare @matthoare20.bsky.social
🌍based at the Early Cancer Institute, University of Cambridge (UK)
🗓️apply by 31 March 2025 www.jobs.cam.ac.uk/job/50461/
👩💻Research Assistant in Computational Biology
🧬analyse somatic mutations in #HCC
👨⚕️international collaboration with Dr Matt Hoare @matthoare20.bsky.social
🌍based at the Early Cancer Institute, University of Cambridge (UK)
🗓️apply by 31 March 2025 www.jobs.cam.ac.uk/job/50461/
🚨🚨Job Alert🚨🚨
Do you have skills in computational biology? Do you want to work on somatic mutations in #hcc?? Do you want to work in an international collaboration with @s-j-aitken.bsky.social? Come and join us in Cambridge!
🗓️ Closing date 31/Mar/2025
www.jobs.cam.ac.uk/job/50461/
Do you have skills in computational biology? Do you want to work on somatic mutations in #hcc?? Do you want to work in an international collaboration with @s-j-aitken.bsky.social? Come and join us in Cambridge!
🗓️ Closing date 31/Mar/2025
www.jobs.cam.ac.uk/job/50461/
Research Assistant (Computational biology) (Fixed Term) - Job Opportunities - University of Cambridge
Research Assistant (Computational biology) (Fixed Term) in the Department of Oncology at the University of Cambridge.
www.jobs.cam.ac.uk
February 25, 2025 at 12:46 PM
🚨🚨Job Alert🚨🚨
Do you have skills in computational biology? Do you want to work on somatic mutations in #hcc?? Do you want to work in an international collaboration with @s-j-aitken.bsky.social? Come and join us in Cambridge!
🗓️ Closing date 31/Mar/2025
www.jobs.cam.ac.uk/job/50461/
Do you have skills in computational biology? Do you want to work on somatic mutations in #hcc?? Do you want to work in an international collaboration with @s-j-aitken.bsky.social? Come and join us in Cambridge!
🗓️ Closing date 31/Mar/2025
www.jobs.cam.ac.uk/job/50461/
Many congratulations to Tom Bird and team from @cruk-si.bsky.social for the new paper on correlation between and human #HCC and murine models with specified oncogenic drivers. A landmark paper years in the making:
rdcu.be/eaxE2
rdcu.be/eaxE2
Human-correlated genetic models identify precision therapy for liver cancer
Nature - As proof of principle, an analysis using a suite of human-aligned immunocompetent mouse models of hepatocellular carcinoma identifies a promising therapeutic candidate, cladribine, which...
rdcu.be
February 19, 2025 at 5:38 PM
Many congratulations to Tom Bird and team from @cruk-si.bsky.social for the new paper on correlation between and human #HCC and murine models with specified oncogenic drivers. A landmark paper years in the making:
rdcu.be/eaxE2
rdcu.be/eaxE2
Reposted by Matt Hoare
📢 Job opportunities!
We're hiring a postdoctoral Research Associate (Fixed Term) in structural biology to join Professor Arthur Kaser's lab at #CITIID and study purine metabolism, autoimmunity, and inflammation.
Apply by 2 February: https://buff.ly/4jmVgkR
@uniofcam.bsky.social
We're hiring a postdoctoral Research Associate (Fixed Term) in structural biology to join Professor Arthur Kaser's lab at #CITIID and study purine metabolism, autoimmunity, and inflammation.
Apply by 2 February: https://buff.ly/4jmVgkR
@uniofcam.bsky.social
Post-doctoral Research Associate (Fixed Term) - Job Opportunities - University of Cambridge
Post-doctoral Research Associate (Fixed Term) in the Department of Medicine at the University of Cambridge.
buff.ly
January 24, 2025 at 11:30 AM
📢 Job opportunities!
We're hiring a postdoctoral Research Associate (Fixed Term) in structural biology to join Professor Arthur Kaser's lab at #CITIID and study purine metabolism, autoimmunity, and inflammation.
Apply by 2 February: https://buff.ly/4jmVgkR
@uniofcam.bsky.social
We're hiring a postdoctoral Research Associate (Fixed Term) in structural biology to join Professor Arthur Kaser's lab at #CITIID and study purine metabolism, autoimmunity, and inflammation.
Apply by 2 February: https://buff.ly/4jmVgkR
@uniofcam.bsky.social
Reposted by Matt Hoare
Join our next #MedicineAtTheCrick event on Thursday 13 March, where researchers and clinicians will explore tissue somatic evolution in ageing and disease.
The event will be hosted by @ciccarellilab.bsky.social and Ilaria Malanchi
www.eventbrite.co.uk/e/medicine-a...
The event will be hosted by @ciccarellilab.bsky.social and Ilaria Malanchi
www.eventbrite.co.uk/e/medicine-a...
Medicine at the Crick
The good, the bad, and the ugly: tissue somatic evolution in ageing and disease
www.eventbrite.co.uk
January 23, 2025 at 5:11 PM
Join our next #MedicineAtTheCrick event on Thursday 13 March, where researchers and clinicians will explore tissue somatic evolution in ageing and disease.
The event will be hosted by @ciccarellilab.bsky.social and Ilaria Malanchi
www.eventbrite.co.uk/e/medicine-a...
The event will be hosted by @ciccarellilab.bsky.social and Ilaria Malanchi
www.eventbrite.co.uk/e/medicine-a...
Reposted by Matt Hoare
Estimated burden of #MASLD and #MASH over the next 30 years.😮
Future is grim if we don't take active approach from all disciplines and angles, including policy change.
jamanetwork.com/journals/jam...
Future is grim if we don't take active approach from all disciplines and angles, including policy change.
jamanetwork.com/journals/jam...
Burden of Metabolic Dysfunction–Associated Steatotic Liver Disease, 2020 to 2050
This decision analytical modeling study estimates the burden of metabolic dysfunction–associated steatotic liver disease among US adults from 2020 to 2050.
jamanetwork.com
January 23, 2025 at 7:58 PM
Estimated burden of #MASLD and #MASH over the next 30 years.😮
Future is grim if we don't take active approach from all disciplines and angles, including policy change.
jamanetwork.com/journals/jam...
Future is grim if we don't take active approach from all disciplines and angles, including policy change.
jamanetwork.com/journals/jam...
Totally rocks, when you get a student onto a PhD fellowship!
someone is holding a fortune cookie that says " i love it when a plan comes together "
ALT: someone is holding a fortune cookie that says " i love it when a plan comes together "
media.tenor.com
January 7, 2025 at 6:00 PM
Totally rocks, when you get a student onto a PhD fellowship!
Reposted by Matt Hoare
A very rare position for an immunology professorship at Cambridge. Something to think about!
www.jobs.cam.ac.uk/job/49381/
www.jobs.cam.ac.uk/job/49381/
Associate Professor/Professor of Infection and/or Immunity - Job Opportunities - University of Cambridge
Associate Professor/Professor of Infection and/or Immunity in the Department of Pathology at the University of Cambridge.
www.jobs.cam.ac.uk
December 13, 2024 at 9:53 AM
A very rare position for an immunology professorship at Cambridge. Something to think about!
www.jobs.cam.ac.uk/job/49381/
www.jobs.cam.ac.uk/job/49381/
All medics and scientists interested in #HCC, the HCC-UK annual conference will be in Manchester on 27th-28th March 2025. Register now at:
hcc-uk.org.uk
hcc-uk.org.uk
HCC-UK
hcc-uk.org.uk
December 11, 2024 at 3:19 PM
All medics and scientists interested in #HCC, the HCC-UK annual conference will be in Manchester on 27th-28th March 2025. Register now at:
hcc-uk.org.uk
hcc-uk.org.uk
Reposted by Matt Hoare
Hello, #MedSky community! We’re excited to begin our Bluesky journey.
Here is a sampling of the trusted, influential, and essential information you can expect when you follow us:
Here is a sampling of the trusted, influential, and essential information you can expect when you follow us:
December 6, 2024 at 8:24 PM
Hello, #MedSky community! We’re excited to begin our Bluesky journey.
Here is a sampling of the trusted, influential, and essential information you can expect when you follow us:
Here is a sampling of the trusted, influential, and essential information you can expect when you follow us: