Matt Hobbs
matthewdavidhobbs.bsky.social
Matt Hobbs
@matthewdavidhobbs.bsky.social
Director of Research at Prostate Cancer UK. Posting in a personal capacity but probably mainly about prostate cancer research possibly with some Everton, NFL, running or food and drink posts sprinkled in.
Reposted by Matt Hobbs
Can targeted SBRT help men with oligoprogressive #prostatecancer avoid chemotherapy for longer?

Dr Priyanka Patel, @alison-tree.bsky.social & team at the Royal Marsden publish results of the @prostateuk.bsky.social funded TRAP trial in @ijrobp.bsky.social

Grab a ☕ & read: doi.org/10.1016/j.ij...
March 18, 2025 at 6:31 PM
Reposted by Matt Hobbs
ICYMI last week, the NPCA's latest publication

"Are evidence-based guidelines translating into clinical practice? A national population-based study of the use of treatment intensification in metastatic hormone-sensitive prostate cancer (mHSPC) in England"

👉 www.ejcancer.com/action/showP...
March 14, 2025 at 11:04 AM
Reposted by Matt Hobbs
⚠️Do you or someone you know want to come and work with me and the fantastic @npca-natcan.bsky.social @natcan-news.bsky.social teams based @collegeofsurgeons.bsky.social? Our oncological clinical lead is the super @alison-tree.bsky.social 😁.

Interested? Apply here www.jobs.ac.uk/job/DMB374/c...
March 11, 2025 at 9:13 AM
Reposted by Matt Hobbs
Reposted by Matt Hobbs
TRAP trial results now out @ijrobp.bsky.social funded by @prostatecanceruk.bsky.social Men oligoprogressing on Abi/Enza for CRPC, nearly 40% progression-free 1 year after SBRT. No significant side effects due to radiotherapy.

www.sciencedirect.com/science/arti...
Stereotactic body radiotherapy for oligoprogressive disease in androgen suppressed prostate cancer: Primary endpoint analysis of the TRAP trial
Optimal management of oligoprogressive prostate cancer whilst on androgen receptor pathway inhibitors (ARPi) is not known. The **** trial tests the ro…
www.sciencedirect.com
March 10, 2025 at 8:43 AM
also flagging this @anzuptrials.bsky.social joint funding op for UK-Australian platform trials. Prostate cancer specifically called out. Happy for us (@prostateukprofs.bsky.social) to help if you want targeted intros to UK researchers www.nhmrc.gov.au/funding/find...
February 26, 2025 at 12:27 PM
Reposted by Matt Hobbs
Dr Neil Ryan's story is just one example of the incredible research opportunities our Starter Grant for Clinical Lecturers scheme offers.

With just 2 weeks left, apply by 5 March 2025 to receive up to £30K to fund your research 🌟

👉 ow.ly/GWKu50V1Soh

#HealthResearch #Grants
February 19, 2025 at 12:06 PM
Reposted by Matt Hobbs
PhD Position available in my lab. Interested in prostate cancer research and developing novel disease models to accelerate research impact then this is for you. Come and join of research community @nucancer.bsky.social
www.findaphd.com/phds/project...
PhD studentship in Prostate Cancer - Refining human prostate tissue culture techniques for better in vivo mimicry and therapeutic insights at Newcastle University on FindAPhD.com
PhD Project - PhD studentship in Prostate Cancer - Refining human prostate tissue culture techniques for better in vivo mimicry and therapeutic insights at Newcastle University, listed on FindAPhD.com
www.findaphd.com
January 30, 2025 at 4:26 PM
Reposted by Matt Hobbs
Are you a Clinical Lecturer looking to develop and strengthen your research career?

The @acmedsci.bsky.social Starter Grants provides £30k funding for up to 2 years.

Deadline: 5 March 2025.

Apply now 👇
prostatecanceruk.org/research/for...

#CareerDevelopment #ResearchFunding
Starter Grants for Clinical Lecturers
We are working with The Academy of Medical Sciences to support Clinical Lecturers who are looking to develop and strengthen their research careers.
prostatecanceruk.org
January 29, 2025 at 9:52 AM
Reposted by Matt Hobbs
Every week, I see a new study talking about this or that effect of GLP-1 receptor agonists like #ozempic. FINALLY, we have a study evaluating all the outcomes (good and bad) in one dataset. There are some... surprises. 🧵
January 22, 2025 at 9:33 PM
Reposted by Matt Hobbs
🏃 Flying start to #IP9ATLAS - first 5️⃣0️⃣ patients recruited!

🔎 Comparing regular MRI scans to standard of care in patients with prostate cancer on active surveillance

🎉 Thank you to our site teams Imperial College Healthcare NHST, Dartford and Gravesham NHST & Frimley Health NHSFT
January 15, 2025 at 1:46 PM
Reposted by Matt Hobbs
Great to see this @prostatecanceruk.bsky.social funded work published!

🥳 Congrats team @asharpmedonc.bsky.social & everyone from @icrlondon.bsky.social

#prostatecancer #research
🧬🧫🔬

This was particularly exciting for me as I was interviewed about the impact of the paper for radio #faceforradio
Could targeting the Heat Shock Factor 1 (HSF1) pathway be a new avenue for treating hormone therapy-resistant #prostatecancer?

@asharpmedonc.bsky.social and the team @icrlondon.bsky.social share their exciting new findings.

Grab a ☕and read: doi.org/10.1158/1078...
January 14, 2025 at 11:12 PM
Reposted by Matt Hobbs
I spy two amazing bluesky-less candidates for the @AACR board of directors. Please consider Johann de Bono @ICR_London @royalmarsdenNHS and Timothy Yap @MDAndersonNews.
www.aacr.org/professional...
Candidates for the AACR Board of Directors
Official candidates for the AACR election of Board of Directors, serving 2024-2027.
www.aacr.org
January 14, 2025 at 8:03 PM
Reposted by Matt Hobbs
Could targeting the Heat Shock Factor 1 (HSF1) pathway be a new avenue for treating hormone therapy-resistant #prostatecancer?

@asharpmedonc.bsky.social and the team @icrlondon.bsky.social share their exciting new findings.

Grab a ☕and read: doi.org/10.1158/1078...
January 14, 2025 at 4:45 PM
Reposted by Matt Hobbs
The National Prostate Cancer Audit State of the Nation Report 2024 has been published! It is available here www.npca.org.uk/reports/npca... alongside its appendix, methodology supplement and data tables.
NPCA State of the Nation Report 2024 - National Prostate Cancer Audit
The aim of the National Prostate Cancer Audit (NPCA) is to evaluate the patterns of care and outcomes for patients with prostate cancer in England and Wales, and to support services to improve the qua...
www.npca.org.uk
January 9, 2025 at 10:15 AM
Hi bluesky prostate folk. Quick question - does anyone know of any papers where a cohort has had both NCCN and CPG prognostic levels assigned/calculated to see how much overlap and outlying there is? Thinking specifically in the intermediate risk groups if that helps.
December 13, 2024 at 4:58 PM
Reposted by Matt Hobbs
My heart sank when I heard the news that Felix Feng has passed away. Felix was such a gentle and uplifting force for so many of us who work in the same field - and for anyone he touched. Although he has left us, his impact will be felt forever. ow.ly/Uc3H50TSBiC
I just helped save a life
You can save one, too. Donate now.
ow.ly
December 11, 2024 at 10:55 AM
Reposted by Matt Hobbs
Proud to see incredible work from @seedgeorge.bsky.social published - tracking PARP inhibitor resistance in prostate cancer in real-time through blood tests. Honored to contribute! @icrlondon.bsky.social 🧬 #medsky #science 🧪
Full paper: sciencedirect.com/science/article/pii/S1535610824004033
Elucidating acquired PARP inhibitor resistance in advanced prostate cancer
PARP inhibition (PARPi) has anti-tumor activity against castration-resistant prostate cancer (CRPC) with homologous recombination repair (HRR) defects…
sciencedirect.com
December 3, 2024 at 3:51 PM
Reposted by Matt Hobbs
Yesterday it was announced that the Research Impact Team @prostatecanceruk.bsky.social is going to become the Research Impact and Engagement Team!

My team will be expanding, so we'll have extra capacity to develop new ways to promote impact and engage with the research community

#excited
a man in a tie is making a funny face with his hands in the air and the words `` so excited ! ''
ALT: a man in a tie is making a funny face with his hands in the air and the words `` so excited ! ''
media.tenor.com
December 3, 2024 at 4:08 PM
Reposted by Matt Hobbs
We strongly suggest that academic publishers and other platforms that host research rapidly implement a Share to Bluesky button for their articles. Here's how:

docs.bsky.app/docs/advance...

#AcademicSky #HigherEd #Altmetrics
Action Intent Links | Bluesky
Authors, websites, and apps can use action intent links to implement "Share on Bluesky" buttons, or similar in-app actions. Logged-in users will be directed to the corresponding action view in the Blu...
docs.bsky.app
November 18, 2024 at 2:48 PM
Reposted by Matt Hobbs
🎨 In case anyone need…

The NIH BioArt Source is an awesome library of *free* professionally drawn illustrations for scientific presentations or figures. Downloadable in HD. Thank you NIH for this invaluable tool 🙏!

Check it out 👇
bioart.niaid.nih.gov
November 23, 2024 at 3:50 PM
Reposted by Matt Hobbs
🆕 Scientists have worked out a way to predict how long #ProstateCancer patients will respond to the PARP inhibitor drug olaparib, according to new research published in #CancerCell.

Read more ⤵️

www.icr.ac.uk/news-archive...
Scientists can predict how long prostate cancer patients will respond to olaparib
Scientists have worked out a way of predicting how long a prostate cancer patient will continue to respond to the PARP inhibitor drug, olaparib, according to new research published in the journal Canc...
www.icr.ac.uk
November 22, 2024 at 8:00 AM
Reposted by Matt Hobbs
Each week my team at Prostate Cancer UK update one of our research we fund webpages. This week the work of Dr George Seed, one of our Travel Prize Fellows, had a little makeover.

#prostatecancer #research

prostatecanceruk.org/research/res...
November 21, 2024 at 5:51 PM
Reposted by Matt Hobbs
Hypoxia-Associated Gene Signatures Are Not Prognostic in High-Risk Localized #ProstateCancer Undergoing ADT With Rad tx

Findings suggest variability in ADT’s hypoxia-modifying effects might undermine the biomarkers’ predictive utility.

@achoud72.bsky.social

www.redjournal.org/article/S036...
November 20, 2024 at 11:15 AM
Reposted by Matt Hobbs
"[Scotland] has detected no cases of cervical cancer in women born between 1988-1996 who were fully vaccinated against HPV between the ages of 12 and 13."

That's honestly so amazing.
HPV vaccine study finds zero cases of cervical cancer among women vaccinated before age 14
In a large Scottish study, no cases of cervical cancer were found among women who received HPV vaccines before they turned 14.
www.statnews.com
September 27, 2024 at 4:56 PM