Mark Mandel
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markjmandel.bsky.social
Mark Mandel
@markjmandel.bsky.social
Bacterial geneticist focused on microbe-animal communication. Professor UW-Madison. Messages are my personal views.
Congratulations to Drew Hryckowian! @a-hryckowian.bsky.social
🎉 Big congratulations to Dr. Andrew Hryckowian on receiving the Vilas Faculty Early-Career Investigator Award! His groundbreaking work on the gut microbiome is shaping the future of infectious disease research.
mmi.wisc.edu/dr-andrew-hr...
November 7, 2025 at 11:00 PM
Reposted by Mark Mandel
Join us Friday as our series features our very own Dr. Sung Chul Park from the Keller Lab!
November 4, 2025 at 9:54 PM
Reposted by Mark Mandel
We are really proud of this report from our 3 colloquia convened by the AAM and supported by the Moore Foundation. A few experts even said they would use it as their introductory textbook for this area. Please check it out!
asm.org ASM @asm.org · 11d
How did life begin, and why does it matter? Scientists are tracing early microbial life–from LUCA to multicellularity–to unlock insights for biotech, climate science and even space exploration. Read the article: asm.org/articles/202...
Early Microbial Evolution | ASM.org
How did life begin, and why does it matter? Scientists are tracing early microbial life—from LUCA to multicellularity—to unlock insights for biotech, climate science and even space exploration.
asm.org
October 30, 2025 at 3:14 PM
Reposted by Mark Mandel
🔬 Applications are now open!

Join MBL’s world-renowned Advanced Research Training Courses, where scientists from around the globe come together to explore new ideas, master cutting-edge techniques, and become part of a dynamic network.

➡️Apply today: go.mbl.edu/courses
Course Offerings | Marine Biological Laboratory
go.mbl.edu
October 28, 2025 at 6:08 PM
Reposted by Mark Mandel
📢 MMI Seminar Series
Friday, Oct. 31 | 1520 MSB
“Regulation of Type 1 Interferon Receptor Signaling”
Dr. Jan Rehwinkel, Oxford University
October 28, 2025 at 4:58 PM
Reposted by Mark Mandel
👇👇👇 come to #mmpc2026 for the science, stay for the Minnesota Microbiology shirts (iykyk)
Mark your calendars! #mmpc2026 The 2026 Midwest Microbial Pathogenesis Conference will be take place September 25-27, 2026 at the University of Minnesota! We are excited to welcome keynote speaker Dr. Andy Camilli. Give us a follow and watch for important information here ➡️ mmpc2026.umn.edu
Midwest Microbial Pathogenesis Conference | Midwest Microbial Pathogenesis Conference 2026
mmpc2026.umn.edu
October 23, 2025 at 11:02 PM
Reposted by Mark Mandel
UMN's Department of Microbiology and Immunology is hiring! Come be our colleague in the Twin Cities! Searches are open for Virology and Fungal Biology (links below).

Virology: hr.myu.umn.edu/jobs/ext/365...
Fungal Biology/Medical Mycology: hr.myu.umn.edu/jobs/ext/365...
October 26, 2025 at 7:40 PM
Reposted by Mark Mandel
R.I.P Hamilton Smith, 1978 Nobel Laureate for the discovery of type II restriction-modification systems (HindII).
October 26, 2025 at 6:54 PM
Reposted by Mark Mandel
Heyyyy we desperately need more archaeologists to volunteer to answer questions from students via video chat through @skypeascientist.bsky.social.

We have 80 unmatched teams. We’ve already matched 650 😵‍💫

If you know any archaeologists, please send them here www.skypeascientist.com/sign-up.html
Sign Up
Skype a Scientist gives you the opportunity to connect with students and the public around the world. ​
www.skypeascientist.com
October 24, 2025 at 1:11 AM
Reposted by Mark Mandel
@joann-trejo.bsky.social, @marymunson4.bsky.social and I have a commentary in @natcellbio.nature.com on recent attacks on DEI in biomedical research: "If scientific research, especially biomedical research, is meant to serve everyone, then it requires that everyone has an opportunity to participate"
Scaling back DEI programmes and the loss of scientific talent
Nature Cell Biology - Programmes that support diversity, equity and inclusion (DEI) in science are under attack in the USA. Data indicate that diversity in the scientific workforce increases...
www.nature.com
October 23, 2025 at 4:36 PM
Reposted by Mark Mandel
Our lab's first paper is out! Led by Jordan Ort, we developed NextClade datasets that enable rapid H5 clade assignment via NextClade. We deployed these during the start of the H5 cattle outbreak, and we finally published the paper in Virus Evolution academic.oup.com/ve/article/1...
Development of avian influenza A(H5) virus datasets for Nextclade enables rapid and accurate clade assignment
Abstract. The 2022 panzootic of highly pathogenic avian influenza (HPAI) A(H5) viruses has led to unprecedented transmission to multiple mammalian species.
academic.oup.com
October 15, 2025 at 3:44 PM
Reposted by Mark Mandel
For ASBMB 2026, each meeting day will have a "theme" organized by session chairs. "Is anyone there?" covers biological communication and interactions across the molecular, cellular, and organismal scales. Eric Betzig will be the keynote and sessions will be lead by Phil Cole and Graham Johnson.
Eric Betzig headlines the #ASBMB26 Deep Dive "Is anyone there? Information transfer in biology from proteins to organisms," exploring how life senses signals & changes the responses of individual proteins or the behaviors of whole animals.
ow.ly/G9jL50X9xLS
#MakeItPossible
October 21, 2025 at 2:28 PM
Reposted by Mark Mandel
New biology: stink bugs inoculate their eggs with a fungus that protects them from parasitoids

www.sciencemagazinedigital.org/sciencemagaz...
Science Magazine - Defensive fungal symbiosis on insect hindlegs
Tympanal organs have repeatedly evolved in diverse insects and were thought to be required for auditory perception (1).
www.sciencemagazinedigital.org
October 17, 2025 at 11:35 AM
Reposted by Mark Mandel
Interested in bacterial sensing, signaling and regulation? Come join us in January at the GRC in sunny California! www.grc.org/sensory-tran...
2026 Sensory Transduction in Microorganisms Conference GRC
The 2026 Gordon Research Conference on Sensory Transduction in Microorganisms will be held in Ventura, California. Apply today to reserve your spot.
www.grc.org
October 15, 2025 at 7:32 AM
Reposted by Mark Mandel
Phages evolve fast, or do they?
In oysters, some stay identical for years.
With >1,200 phages & 600 Vibrio genomes, we reveal long-term stability and new mobile elements.
Proud of this collaborative work across our teams (Roscoff-UdeM and @epcrocha.bsky.social www.biorxiv.org/cgi/content/...
Ecological constraints foster both extreme viral-host lineage stability and mobile element diversity in a marine community
Phages are typically viewed as very rapidly evolving biological entities. Little is known, however, about whether and how phages can establish long-term genetic stability. We addressed this eco-evolut...
www.biorxiv.org
October 12, 2025 at 9:16 PM
October baseball ❤️
October 12, 2025 at 12:10 AM
Reposted by Mark Mandel
Glad to share a collaboration with Yicen Lin's group at Kunming University of Science and Technology published in ISME Journal

Synergistic biodegradation of polyethylene by experimentally evolved bacterial biofilms
academic.oup.com/ismej/advanc...

#MicrobiomeEcology at #LeidenBiology
October 9, 2025 at 6:54 AM
Reposted by Mark Mandel
We're hiring! Check out our ad and please re-post or forward to interested #Microbiology parties: apply.interfolio.com/174783
Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio
apply.interfolio.com
October 7, 2025 at 4:10 PM
Reposted by Mark Mandel
OIST is seeking up to four tenure-track or tenured faculty in Ecology, Environmental Science, Earth Science, and Oceanography. Application deadline: Oct 15. Please share. Thx!
www.oist.jp/careers/facu...
October 7, 2025 at 10:01 AM
Reposted by Mark Mandel
Important piece from Sarah Stanley at Berkeley on new NIH definitions that can be construed to arbitrarily halt research that is both safe and important to public health and future cures www.statnews.com/2025/10/06/g... via @statnews.com
The NIH ordered me to stop my ‘dangerous’ gain-of-function research. It isn’t dangerous at all
Safe gain-of-function research is necessary to identify new treatments for diseases like for tuberculosis — but the NIH has imposed unfounded stops.
www.statnews.com
October 6, 2025 at 12:15 PM
Reposted by Mark Mandel
UChicago Microbiology is searching for tenured or tenure-track faculty working in host-pathogens interactions, viral and bacterial pathogenesis, and emerging infectious diseases. Come join our vibrant Department! microbiology.uchicago.edu
Apply here apply.interfolio.com/174404
Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio
apply.interfolio.com
October 5, 2025 at 12:03 PM
Another great @mmpconference.bsky.social wraps up… 👏 to organizers Jonathan Allen and Abby Kroken! @akroken.bsky.social
October 5, 2025 at 9:24 PM
Reposted by Mark Mandel
www.biorxiv.org/content/10.1...
Great story in collaboration with @pierremarcdelaux.bsky.social and @jeanmichelane.bsky.social groups. EPP1 story continues after many years of collaborations with Pierre-Marc and Jean-Michel!!!
EPP1 is an ancestral component of the plant Common Symbiosis Pathway
The success of plants on land has been enabled by mutualistic intracellular associations with microbes for 450 million years (Delaux and Schornack 2021). Because of their intracellular nature, the est...
www.biorxiv.org
October 2, 2025 at 8:11 PM