Mark Mandel
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markjmandel.bsky.social
Mark Mandel
@markjmandel.bsky.social
Bacterial geneticist focused on microbe-animal communication. Professor UW-Madison. Messages are my personal views.
Karen Visick starts out the morning at #ASMBiofilms with the Costerton Award Lecture! @microklv.bsky.social
November 11, 2025 at 4:20 PM
October baseball ❤️
October 12, 2025 at 12:10 AM
Another great @mmpconference.bsky.social wraps up… 👏 to organizers Jonathan Allen and Abby Kroken! @akroken.bsky.social
October 5, 2025 at 9:24 PM
The Computational Modeling in Biology Network (COMBINE 2025) workshop is being held at UW-Madison October 20-23. Great lineup of speakers and workshop leaders. Early registration through this Sunday. co.mbine.org/author/combi...
September 26, 2025 at 3:39 PM
Join us on Friday at noon for a great seminar from Tera Levin @teralevin.bsky.social! @uwmadisonmmi.bsky.social
September 24, 2025 at 5:08 PM
Are you a bacterial geneticist looking for a football player to root for this year? Obvious choice is LAC McConkey.

His name is Ladd McConkey and he plays for LAC. Went to microbiology powerhouse Georgia so that checks out.
September 4, 2025 at 8:07 PM
Gearing up for a fantastic Fall Seminar Series @uwmadisonmmi.bsky.social! Kickoff is this Friday with the Dr. Rod Welch Distinguished Lecture by Vic DiRita!
September 3, 2025 at 3:05 PM
Congratulations to Avery Imes and all of our collaborators on this cover & editor's spotlight article in #AEM! More details on the study in the preprint thread linked below. @asm.org bsky.app/profile/mark...
August 25, 2025 at 3:54 PM
Congratulations to Dr. Jacob Vander Griend on his successful PhD defense today! Really proud of all of your work on systems-level studies in Vibrio fischeri. @uwmadisonmdtp.bsky.social @uwmadisonmmi.bsky.social
August 12, 2025 at 2:39 AM
Beautiful night in Madison, Wisconsin.
July 7, 2025 at 1:05 AM
My lab is doing the hard work to prepare for a conference next month: taste testing to figure out if egg sandwiches should be served on English muffins or donuts.
May 20, 2025 at 3:07 PM
Great to have my former labmate and @uwmadisonmdtp.bsky.social alum Sarah Studer back in Madison. Of course we celebrated with Babcock Ice Cream!
April 12, 2025 at 1:06 AM
Join us for Friday's Noon seminar from Laurie Comstock on "Mobile Genetic Elements of Gut Bacteroidales: Phenotypes and Fitness"! @uwmadisonmmi.bsky.social
April 9, 2025 at 4:47 PM
Very excited for @benwolfe.bsky.social's seminar today in @uwbact.bsky.social, hosted by the @uwmadisonmdtp.bsky.social students!!
March 20, 2025 at 3:52 PM
With more mollusk genomes available, a new genome-based phylogeny is featured on the cover of Science. Paper from @sigwartae.bsky.social at www.science.org/doi/10.1126/... Cover photo by Magnus Lundgren.
February 28, 2025 at 12:47 PM
Today's @uwmadisonmmi.bsky.social seminar is from Luisa Cervantes-Barragan from Emory!
February 7, 2025 at 2:54 PM
Excited for our @uwmadisonmmi.bsky.social seminar this Friday at noon from @stallingslab.bsky.social on "Molecular pathogenesis of Mycobacteria"!
January 22, 2025 at 4:03 PM
Join us at noon today for the @uwmadisonmmi.bsky.social seminar from @jschoggins.bsky.social!
January 17, 2025 at 2:31 PM
Hmm… I don’t see one of the most exciting results in the thread above so adding again: The paper shows that the E. berryi isolates encode a Type VI secretion system and that those systems are functional in culture and during squid colonization.
January 15, 2025 at 1:56 PM
Overall, our work suggests that the Hummingbird bobtail squid (the bigger one!) is likely to be a valuable comparative model for mechanistic studies of symbiosis.
January 15, 2025 at 1:45 PM
Finally, early host responses to symbiosis including apoptosis and hemocyte migration are conserved in the Hummingbird bobtail.
January 15, 2025 at 1:45 PM
Bacterial mutants that fail to engage in flagellar motility, SYP biofilm, or produce the symbiotic luminescence had identical phenotypes in the Hummingbird bobtail as they have in the Hawaiian bobtail squid.
January 15, 2025 at 1:45 PM
Fluorescent protein-expressing strains revealed the crypt structure of the Hummingbird bobtail squid light organ, which strongly resembled that of the Hawaiian bobtail (3 crypts x 2 sides = 6 crypts per animal).
January 15, 2025 at 1:45 PM
We started by isolating symbionts from the Hummingbird bobtail squid, and found that like the Hawaiian host, there is strong specificity with only being colonized by Vibrio fischeri.
January 15, 2025 at 1:45 PM
Hector Burgos prepared a tome (!) of protocols on how to generate, compete, and analyze barcoded-deletions in Vibrio fischeri. Check it out if you'd like to apply these approaches! currentprotocols.onlinelibrary.wiley.com/doi/10.1002/...
December 9, 2024 at 3:09 PM