#NEWS: #BCMNeurosurgery's Dr. Ben Deneen recently received the inaugural Bert O'Malley Award for Outstanding Basic Research at this year's Dan L Duncan Comprehensive Cancer Center at @bcmhouston.bsky.social annual retreat.

"A functional perspective on astrocyte heterogeneity"
http://dlvr.it/TPML8T

Benjamin Deneen, Wookbong Kwon & @m-r-williamson.bsky.social
@cp-trendsneuro.bsky.social
#SfN2025

Please share or forward to anyone interested in joining our lab as a research assistant, details can be found via the link below

shorturl.at/x0cSs

Lest We Forget
N'oublions Jamais

In honor of Veterans Day, Dr. Timothy Porea shares how he uses his time in the U.S. Navy and military medicine to help current military students. Watch the interview with Dr. Porea on YouTube: https://bit.ly/4p6AUi0 Thank you to all veterans who support Baylor and the community. #VeteransDay

DNA replication is only half the story. Cells actually replicate their chromatin, ensuring that both the DNA sequences and the chromatin states are faithfully maintained to preserve cell identity and function after division. Here's a glimpse of how this process unfolds, courtesy of theCrux:

This week, that idea reached patients: Viral-mimicry priming + anti-PD-1 in relapsed/refractory NK/T-cell lymphoma delivered 47.6% complete responses, 66.7% ORR, and ~50% 2-year OS, even after prior PD-1 failure (Huang, Cancer Discovery 2025).

EZHIP has been puzzling us for years because of its incompletely understood role in pediatric brain tumors. Here we report new functions for EZHIP and that EZHIP is not only mutated in PFA ependymoma, but also in K27M+ HGGs with EGFR mutations.
actaneurocomms.biomedcentral.com/articles/10....

1/ Excited to share our new study with @brumbaugh-lab.bsky.social, out in @natbiotech.nature.com! P-bodies selectively sequester RNAs encoding cell fate regulators, often from the preceding developmental stage. Releasing these RNAs can drive changes in cell identity. 🧵 www.nature.com/articles/s41...

Scientists uncover nuclear droplets that link multiple #leukemias revealing new #therapeuticTarget.
@gandhardatar.bsky.social @sciencyelmira.bsky.social @goodell-lab.bsky.social @superscijew.bsky.social et al
@cellcellpress.bsky.social @bcmhouston.bsky.social www.bcm.edu/news/scienti...

(1/10) How do diverse leukemia mutations converge on the same molecular program? In #RibackLab first manuscript @cp-cell.bsky.social, collaboration with @goodell-lab.bsky.social shows that disparate mutations rewire shared protein networks to form nuclear condensates called C-bodies.

The November issue of Cancer Discovery @aacrjournals.bsky.social is online! The cover features work by Diwakar Davar, @overacrelab.bsky.social, et al. showing sucralose consumption ablates cancer immunotherapy response via microbiome disruption - read that & more: aacrjournals.org/cancerdiscov...

Our "mind captioning" paper is now published in Science Advances @science.org .
The method generates descriptive text of what we perceive and recall from brain activity — a linguistic interpretation of nonverbal mental content rather than language decoding.

doi.org/10.1126/scia...

Our latest collaboration with @rongfan8.bsky.social, spatial triomics to investigate myelin and cortical brain development, and demyelination, spearheaded by Leslie Kirby in our lab @ki.se and Di Zhang in Rong's lab! Check it out @nature.com

www.nature.com/articles/s41...

The Pathania lab will be moving to the Ludwig Institute in Oxford in early 2026. We'll be recruiting postdocs and research assistants soon, so keep an eye out for those job ads and reach out if you want to find out more about the science we have planned!

shorturl.at/thpyK