Dan
@ltdanpharm.bsky.social
Small-town Hospital Pharmacist interested in ID and Stewardship. Enjoying Colorado living. 🏔 Tennis fan 🎾.
Reposted by Dan
🔥🔥Just published 🔥🔥
ATS CAP guidelines 2025
Diagnosis and Management of Community-acquired Pneumonia. An Official American Thoracic Society Clinical Practice Guideline
Free access pdf #IDsky#EMIMCC
www.atsjournals.org/doi/10.1164/...
ATS CAP guidelines 2025
Diagnosis and Management of Community-acquired Pneumonia. An Official American Thoracic Society Clinical Practice Guideline
Free access pdf #IDsky#EMIMCC
www.atsjournals.org/doi/10.1164/...
Diagnosis and Management of Community-acquired Pneumonia. An Official American Thoracic Society Clinical Practice Guideline | American Journal of Respiratory and Critical Care Medicine | Articles in P...
www.atsjournals.org
July 20, 2025 at 6:45 AM
🔥🔥Just published 🔥🔥
ATS CAP guidelines 2025
Diagnosis and Management of Community-acquired Pneumonia. An Official American Thoracic Society Clinical Practice Guideline
Free access pdf #IDsky#EMIMCC
www.atsjournals.org/doi/10.1164/...
ATS CAP guidelines 2025
Diagnosis and Management of Community-acquired Pneumonia. An Official American Thoracic Society Clinical Practice Guideline
Free access pdf #IDsky#EMIMCC
www.atsjournals.org/doi/10.1164/...
Reposted by Dan
🆕💫 Viewpoint JAMA
Nitrites for Urinary Tract Infection—Time to Say Goodbye?
#idsky #EMIMCC #UTIsky
jamanetwork.com/journals/jam...
Nitrites for Urinary Tract Infection—Time to Say Goodbye?
#idsky #EMIMCC #UTIsky
jamanetwork.com/journals/jam...
Nitrites for Urinary Tract Infection
This Viewpoint examines the urinary nitrite test and questions its effectiveness and relevance in distinguishing between urinary tract infection and asymptomatic bacteriuria.
jamanetwork.com
May 5, 2025 at 8:46 PM
🆕💫 Viewpoint JAMA
Nitrites for Urinary Tract Infection—Time to Say Goodbye?
#idsky #EMIMCC #UTIsky
jamanetwork.com/journals/jam...
Nitrites for Urinary Tract Infection—Time to Say Goodbye?
#idsky #EMIMCC #UTIsky
jamanetwork.com/journals/jam...
Reposted by Dan
Follow us on Bluesky!
April 28, 2025 at 12:05 PM
Follow us on Bluesky!
I've always avoided Cephalexin for Osteomyelitis. But I attended a lecture this weekend and the speaker said they commonly use it for osteo/septic joint. Anyone else doing this? If so, 1g QID? TID? #IDSky
April 21, 2025 at 11:35 PM
I've always avoided Cephalexin for Osteomyelitis. But I attended a lecture this weekend and the speaker said they commonly use it for osteo/septic joint. Anyone else doing this? If so, 1g QID? TID? #IDSky
Anyone at HCA or another Meditech facility and able to share their CAP or Cellulitis order set? I'm trying to increase our use of the sets, but I think our build/layout is the problem... #IDSky
April 20, 2025 at 1:35 PM
Anyone at HCA or another Meditech facility and able to share their CAP or Cellulitis order set? I'm trying to increase our use of the sets, but I think our build/layout is the problem... #IDSky
Reposted by Dan
Vancomycin Taper trial presented by @dremilymcd.bsky.social #ESCMID2025. In people who get better by day 10 should we stop or give taper? Reduced recurrences by primary outcome timepoint but the KM suggests it may be just delaying rather than truly preventing recurrence? #IDSky
April 13, 2025 at 3:38 PM
Vancomycin Taper trial presented by @dremilymcd.bsky.social #ESCMID2025. In people who get better by day 10 should we stop or give taper? Reduced recurrences by primary outcome timepoint but the KM suggests it may be just delaying rather than truly preventing recurrence? #IDSky
Reposted by Dan
Thanks to @absteward.bsky.social for finding 2 RCTs of shorter (1 IM dose) vs. longer (3 weekly IM doses) of PCN for "Early Syphilis"! Added to the Shorter Is Better Table. 23 distinct conditions now reported in the table!
References at
www.bradspellberg.com/shorter-is-b...
References at
www.bradspellberg.com/shorter-is-b...
February 14, 2025 at 5:35 PM
Thanks to @absteward.bsky.social for finding 2 RCTs of shorter (1 IM dose) vs. longer (3 weekly IM doses) of PCN for "Early Syphilis"! Added to the Shorter Is Better Table. 23 distinct conditions now reported in the table!
References at
www.bradspellberg.com/shorter-is-b...
References at
www.bradspellberg.com/shorter-is-b...
Reposted by Dan
🔥A sneak peak on the upcoming IDSA guidelines for cUTI🔥
Public Comment: IDSA Guideline on Management and Treatment of Complicated Urinary Tract Infections
So it's still not published yet ! #idsky #medsky #utisky
www.idsociety.org/practice-gui...
Public Comment: IDSA Guideline on Management and Treatment of Complicated Urinary Tract Infections
So it's still not published yet ! #idsky #medsky #utisky
www.idsociety.org/practice-gui...
February 19, 2025 at 9:56 PM
🔥A sneak peak on the upcoming IDSA guidelines for cUTI🔥
Public Comment: IDSA Guideline on Management and Treatment of Complicated Urinary Tract Infections
So it's still not published yet ! #idsky #medsky #utisky
www.idsociety.org/practice-gui...
Public Comment: IDSA Guideline on Management and Treatment of Complicated Urinary Tract Infections
So it's still not published yet ! #idsky #medsky #utisky
www.idsociety.org/practice-gui...
Reposted by Dan
In patients with cUTI (including acute pyelonephritis) treated initially with parenteral therapy who are clinically improving,able to take oral medication,and for whom an effective oral option is available,we suggest transitioning to oral antibiotics rather than continuing IV Abx #idsky #EMIMCC
🔥A sneak peak on the upcoming IDSA guidelines for cUTI🔥
Public Comment: IDSA Guideline on Management and Treatment of Complicated Urinary Tract Infections
So it's still not published yet ! #idsky #medsky #utisky
www.idsociety.org/practice-gui...
Public Comment: IDSA Guideline on Management and Treatment of Complicated Urinary Tract Infections
So it's still not published yet ! #idsky #medsky #utisky
www.idsociety.org/practice-gui...
February 19, 2025 at 10:13 PM
Reposted by Dan
We are delighted to announce that we have begun to assemble a team for Bacteremia WikiGuideline.
Join us to create guidelines with the humility of uncertainty.
Join us to create guidelines with the humility of uncertainty.
Microsoft Forms
forms.office.com
February 10, 2025 at 1:15 AM
We are delighted to announce that we have begun to assemble a team for Bacteremia WikiGuideline.
Join us to create guidelines with the humility of uncertainty.
Join us to create guidelines with the humility of uncertainty.
For diabetic foot osteomyelitis, Amox/clav 875/125, do you typically go with BID or TID? Assuming the patient is not obese nor underweight. #IDSky
January 29, 2025 at 1:38 PM
For diabetic foot osteomyelitis, Amox/clav 875/125, do you typically go with BID or TID? Assuming the patient is not obese nor underweight. #IDSky
Reposted by Dan
ONE ANTIBIOTIC PK TABLE TO RULE THEM ALL
Absorption takes drug into blood from GI,
Vd spreads drug out to where bug calls home.
And after bacteria are doomed to die,
The drug’s eliminated on the porcelain throne
In the Land of Notion where this table doth lie…
#idSky #microsky #pharmsky #medsky
Absorption takes drug into blood from GI,
Vd spreads drug out to where bug calls home.
And after bacteria are doomed to die,
The drug’s eliminated on the porcelain throne
In the Land of Notion where this table doth lie…
#idSky #microsky #pharmsky #medsky
January 26, 2025 at 7:48 PM
Reposted by Dan
Well, it’s official folks. We’re on BlueSky full time. You want to interact with us? Do it here, don’t message on X/twitter.
Don’t want to interact with us? Perfectly understandable, continue to ignore us, probably the best thing for all concerned.
Don’t want to interact with us? Perfectly understandable, continue to ignore us, probably the best thing for all concerned.
January 21, 2025 at 6:56 PM
Well, it’s official folks. We’re on BlueSky full time. You want to interact with us? Do it here, don’t message on X/twitter.
Don’t want to interact with us? Perfectly understandable, continue to ignore us, probably the best thing for all concerned.
Don’t want to interact with us? Perfectly understandable, continue to ignore us, probably the best thing for all concerned.
Reposted by Dan
Though "Oral is the New IV" with antibiotics (h/t @bradspellberg.bsky.social), it's not always easy to convince reluctant inpatient clinicians -- especially (in my experience) surgeons, who want to treat "aggressively".
Interesting dynamic ...
blogs.jwatch.org/hiv-id-obser...
Interesting dynamic ...
blogs.jwatch.org/hiv-id-obser...
On the Inpatient ID Consult Service, Oral Antibiotics Have a Rocky Road to Acceptance
Having just completed a stint doing inpatient ID consults, I came away impressed with three things: Staph aureus remains the Ruler of Evil Invasive Pathogens in the hospital setting. You can “jinx” a ...
blogs.jwatch.org
January 3, 2025 at 6:53 PM
Though "Oral is the New IV" with antibiotics (h/t @bradspellberg.bsky.social), it's not always easy to convince reluctant inpatient clinicians -- especially (in my experience) surgeons, who want to treat "aggressively".
Interesting dynamic ...
blogs.jwatch.org/hiv-id-obser...
Interesting dynamic ...
blogs.jwatch.org/hiv-id-obser...
Reposted by Dan
🆕🔥Just published 🔥🆕
Updates on the Treatment of Drug-Susceptible and Drug-Resistant Tuberculosis(TB)
An Official ATS/CDC/ERS/IDSA Clinical Practice Guideline #idsky #TBsky
www.atsjournals.org/doi/full/10....
Updates on the Treatment of Drug-Susceptible and Drug-Resistant Tuberculosis(TB)
An Official ATS/CDC/ERS/IDSA Clinical Practice Guideline #idsky #TBsky
www.atsjournals.org/doi/full/10....
January 2, 2025 at 6:53 PM
🆕🔥Just published 🔥🆕
Updates on the Treatment of Drug-Susceptible and Drug-Resistant Tuberculosis(TB)
An Official ATS/CDC/ERS/IDSA Clinical Practice Guideline #idsky #TBsky
www.atsjournals.org/doi/full/10....
Updates on the Treatment of Drug-Susceptible and Drug-Resistant Tuberculosis(TB)
An Official ATS/CDC/ERS/IDSA Clinical Practice Guideline #idsky #TBsky
www.atsjournals.org/doi/full/10....
Remdesivir
Are most people doing 3 days for a non-covid admit diagnosis? If so (or if 5), are you continuing beyond discharge?
For covid admits, are you continuing beyond discharge in any patient populations?
Anyone using any specific restrictions beyond guideline (IDSA) recommendations? #IDSky
Are most people doing 3 days for a non-covid admit diagnosis? If so (or if 5), are you continuing beyond discharge?
For covid admits, are you continuing beyond discharge in any patient populations?
Anyone using any specific restrictions beyond guideline (IDSA) recommendations? #IDSky
January 1, 2025 at 2:03 AM
Remdesivir
Are most people doing 3 days for a non-covid admit diagnosis? If so (or if 5), are you continuing beyond discharge?
For covid admits, are you continuing beyond discharge in any patient populations?
Anyone using any specific restrictions beyond guideline (IDSA) recommendations? #IDSky
Are most people doing 3 days for a non-covid admit diagnosis? If so (or if 5), are you continuing beyond discharge?
For covid admits, are you continuing beyond discharge in any patient populations?
Anyone using any specific restrictions beyond guideline (IDSA) recommendations? #IDSky
Reposted by Dan
I have many thoughts! Let’s talk about Cefalexin use in bacteraemia!
A new year’s thread…
A new year’s thread…
December 30, 2024 at 11:14 PM
I have many thoughts! Let’s talk about Cefalexin use in bacteraemia!
A new year’s thread…
A new year’s thread…
Reposted by Dan
🆕🔥Clinical Insights #JAMAInternalMed
When Can a MRSA Nares Swab Guide Antibiotic Stewardship?
What the Nose Knows #idsky #medsky #AMSsky #EMIMCC
jamanetwork.com/journals/jam...
When Can a MRSA Nares Swab Guide Antibiotic Stewardship?
What the Nose Knows #idsky #medsky #AMSsky #EMIMCC
jamanetwork.com/journals/jam...
When Can a MRSA Nares Swab Guide Antibiotic Stewardship?
This Clinical Insights discusses how the methicillin-resistant Staphylococcus aureus (MRSA) nares swab may be used alongside disease prevalence and clinical factors to determine when MRSA coverage is ...
jamanetwork.com
December 9, 2024 at 4:21 PM
🆕🔥Clinical Insights #JAMAInternalMed
When Can a MRSA Nares Swab Guide Antibiotic Stewardship?
What the Nose Knows #idsky #medsky #AMSsky #EMIMCC
jamanetwork.com/journals/jam...
When Can a MRSA Nares Swab Guide Antibiotic Stewardship?
What the Nose Knows #idsky #medsky #AMSsky #EMIMCC
jamanetwork.com/journals/jam...
Reposted by Dan
🔥The ADAPT-Sepsis RCT🔥
Daily PCT-guided protocol 🔽 total antibiotic duration & had noninferior all-cause mortality compared with standard care.
No difference was found in total Abx duration between standard care & daily CRP-guided protocol
CRP failure #idsky #EMIMCC
jamanetwork.com/journals/jam...
Daily PCT-guided protocol 🔽 total antibiotic duration & had noninferior all-cause mortality compared with standard care.
No difference was found in total Abx duration between standard care & daily CRP-guided protocol
CRP failure #idsky #EMIMCC
jamanetwork.com/journals/jam...
Biomarker-Guided Antibiotic Duration for Patients With Suspected Sepsis
This clinical trial assessed whether treatment protocols for monitoring C-reactive protein or procalcitonin safely reduced the amount of time critically ill adults with suspected sepsis received antib...
jamanetwork.com
December 10, 2024 at 3:39 AM
🔥The ADAPT-Sepsis RCT🔥
Daily PCT-guided protocol 🔽 total antibiotic duration & had noninferior all-cause mortality compared with standard care.
No difference was found in total Abx duration between standard care & daily CRP-guided protocol
CRP failure #idsky #EMIMCC
jamanetwork.com/journals/jam...
Daily PCT-guided protocol 🔽 total antibiotic duration & had noninferior all-cause mortality compared with standard care.
No difference was found in total Abx duration between standard care & daily CRP-guided protocol
CRP failure #idsky #EMIMCC
jamanetwork.com/journals/jam...
www.clinicalmicrobiologyandinfection.com/article/S119...
Finally reviewed this one. @bradspellberg.bsky.social After reading this, do you trend or use CRP in any infection? Osteo?
Finally reviewed this one. @bradspellberg.bsky.social After reading this, do you trend or use CRP in any infection? Osteo?
DEFINE_ME
www.clinicalmicrobiologyandinfection.com
December 7, 2024 at 1:01 AM
www.clinicalmicrobiologyandinfection.com/article/S119...
Finally reviewed this one. @bradspellberg.bsky.social After reading this, do you trend or use CRP in any infection? Osteo?
Finally reviewed this one. @bradspellberg.bsky.social After reading this, do you trend or use CRP in any infection? Osteo?
Enterobacter cloacae complex. Ertapenem is suppressed from the culture. My lab tells me this is due to an FDA indication for use. Can anyone elaborate on this? #IDSky
December 2, 2024 at 5:10 PM
Enterobacter cloacae complex. Ertapenem is suppressed from the culture. My lab tells me this is due to an FDA indication for use. Can anyone elaborate on this? #IDSky
Reposted by Dan
December 1, 2024 at 5:17 PM
Reposted by Dan
For my inaugural post, Im proud to announce the publication of our Safer@Home care model. This is going to change how medicine is practiced. No need to admit pts "for IV antibiotics" anymore. Or just for IV diuresis in CHF. Or just for EtOH withdrawal. Etc.
jamanetwork.com/journals/jam...
jamanetwork.com/journals/jam...
Virtual Home Care for Patients With Acute Illness
This cohort study compares outcomes of patients receiving care in an outpatient, virtual, home-based acute care model with outcomes of patients receiving standard hospital care.
jamanetwork.com
November 30, 2024 at 9:24 PM
For my inaugural post, Im proud to announce the publication of our Safer@Home care model. This is going to change how medicine is practiced. No need to admit pts "for IV antibiotics" anymore. Or just for IV diuresis in CHF. Or just for EtOH withdrawal. Etc.
jamanetwork.com/journals/jam...
jamanetwork.com/journals/jam...